J J Halperin

Summary

Affiliation: Morristown Memorial Hospital
Country: USA

Publications

  1. doi request reprint Nervous system Lyme disease
    John J Halperin
    Department of Neurosciences, Atlantic Neuroscience Institute and Overlook Hospital, Summit, NJ 07902, USA
    Infect Dis Clin North Am 22:261-74, vi. 2008
  2. ncbi request reprint Prolonged Lyme disease treatment: enough is enough
    John J Halperin
    Neurology 70:986-7. 2008
  3. doi request reprint A tale of two spirochetes: lyme disease and syphilis
    John J Halperin
    Department of Neurology, Madison Avenue, Mount Sinai School of Medicine, NY, USA
    Neurol Clin 28:277-91. 2010
  4. doi request reprint Nervous system Lyme disease, chronic Lyme disease, and none of the above
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, Summit, NJ, USA
    Acta Neurol Belg 116:1-6. 2016
  5. doi request reprint Nervous System Lyme Disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, 99 Beauvoir Avenue, Summit, NJ 07902, USA Sidney Kimmel Medical College of Thomas Jefferson University, 132 South, 10th Street, Philadelphia, PA 19107, USA Electronic address
    Clin Lab Med 35:779-95. 2015
  6. doi request reprint Nervous system Lyme disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, 99 Beauvoir Avenue, Summit, NJ 07902, USA Department of Neurology and Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA Electronic address
    Infect Dis Clin North Am 29:241-53. 2015
  7. doi request reprint Nervous system Lyme disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, Summit, NJ, USA Electronic address
    Handb Clin Neurol 121:1473-83. 2014
  8. doi request reprint Lyme disease: a multisystem infection that affects the nervous system
    John J Halperin
    Overlook Medical Center, Department of Neurosciences, 99 Beauvoir Ave, Summit, NJ 07902, USA
    Continuum (Minneap Minn) 18:1338-50. 2012
  9. doi request reprint Common misconceptions about Lyme disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, Atlantic Health System, Summit, NJ 07902, USA
    Am J Med 126:264.e1-7. 2013
  10. doi request reprint Nervous system lyme disease: is there a controversy?
    John J Halperin
    Department of Neurosciences, Overlook Hospital and Atlantic Neuroscience Institute, Summit, New Jersey 07902, USA
    Semin Neurol 31:317-24. 2011

Detail Information

Publications20

  1. doi request reprint Nervous system Lyme disease
    John J Halperin
    Department of Neurosciences, Atlantic Neuroscience Institute and Overlook Hospital, Summit, NJ 07902, USA
    Infect Dis Clin North Am 22:261-74, vi. 2008
    ..In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit...
  2. ncbi request reprint Prolonged Lyme disease treatment: enough is enough
    John J Halperin
    Neurology 70:986-7. 2008
  3. doi request reprint A tale of two spirochetes: lyme disease and syphilis
    John J Halperin
    Department of Neurology, Madison Avenue, Mount Sinai School of Medicine, NY, USA
    Neurol Clin 28:277-91. 2010
    ....
  4. doi request reprint Nervous system Lyme disease, chronic Lyme disease, and none of the above
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, Summit, NJ, USA
    Acta Neurol Belg 116:1-6. 2016
    ..burgdorferi infection, is inappropriate and unfortunate, leading not only to unneeded treatment and its associated complications, but also to missed opportunities for more appropriate management of patients' often disabling symptoms. ..
  5. doi request reprint Nervous System Lyme Disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, 99 Beauvoir Avenue, Summit, NJ 07902, USA Sidney Kimmel Medical College of Thomas Jefferson University, 132 South, 10th Street, Philadelphia, PA 19107, USA Electronic address
    Clin Lab Med 35:779-95. 2015
    ..Most cases of neuroborreliosis can be cured with oral doxycycline; parenteral regimens should be reserved for patients with particularly severe disease. ..
  6. doi request reprint Nervous system Lyme disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, 99 Beauvoir Avenue, Summit, NJ 07902, USA Department of Neurology and Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA Electronic address
    Infect Dis Clin North Am 29:241-53. 2015
    ..Severe cases may require parenteral treatment. The fatigue and cognitive symptoms seen in some patients with extra-neurological disease are neither evidence of CNS infection nor specific to Lyme disease. ..
  7. doi request reprint Nervous system Lyme disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, Summit, NJ, USA Electronic address
    Handb Clin Neurol 121:1473-83. 2014
    ..Treatment should usually be for 2 to at most 4 weeks. Longer treatment adds no therapeutic benefit but does add substantial risk. ..
  8. doi request reprint Lyme disease: a multisystem infection that affects the nervous system
    John J Halperin
    Overlook Medical Center, Department of Neurosciences, 99 Beauvoir Ave, Summit, NJ 07902, USA
    Continuum (Minneap Minn) 18:1338-50. 2012
    ..This article will enable the reader to diagnose and treat nervous system Lyme disease appropriately...
  9. doi request reprint Common misconceptions about Lyme disease
    John J Halperin
    Department of Neurosciences, Overlook Medical Center, Atlantic Health System, Summit, NJ 07902, USA
    Am J Med 126:264.e1-7. 2013
    ..In this article we review the principal misconceptions, discussing their origins and the best currently available scientific evidence related to each one...
  10. doi request reprint Nervous system lyme disease: is there a controversy?
    John J Halperin
    Department of Neurosciences, Overlook Hospital and Atlantic Neuroscience Institute, Summit, New Jersey 07902, USA
    Semin Neurol 31:317-24. 2011
    ..For some (cerebral vasculitis with stroke, optic neuritis) a few case reports suggest a rare possible causal link...
  11. ncbi request reprint Neurologic manifestations of lyme disease
    John J Halperin
    Department of Neurosciences, Overlook Hospital and Atlantic Health, 99 Beauvoir Avenue, Summit, NJ 07902, USA
    Curr Infect Dis Rep 13:360-6. 2011
    ..When present as part of Lyme disease, they do not require additional or different treatment...
  12. doi request reprint Nervous system Lyme disease
    J J Halperin
    Atlantic Neuroscience Institute, Summit, New Jersey, USA
    J R Coll Physicians Edinb 40:248-55. 2010
    ..Treatment with any of several standard regimens of oral or parenteral antimicrobials is highly effective. Prolonged treatment beyond four weeks is rarely if ever warranted, and carries significant risk...
  13. ncbi request reprint Diagnosis and treatment of the neuromuscular manifestations of lyme disease
    John J Halperin
    John J Halperin, MD Atlantic Neuroscience Institute and New York University School of Medicine, Overlook Hospital, 99 Beauvoir Avenue, Summit, NJ 07902, USA
    Curr Treat Options Neurol 9:93-100. 2007
    ..This may be equally valid in patients infected with the strains prevalent in the United States, but this remains to be established...
  14. ncbi request reprint Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology
    J J Halperin
    Department of Neurosciences, Overlook Hospital, NYU School of Medicine, Summit, NJ, USA
    Neurology 69:91-102. 2007
    ..Three questions were addressed: 1) Which antimicrobial agents are effective? 2) Are different regimens preferred for different manifestations of nervous system Lyme disease? 3) What duration of therapy is needed?..
  15. ncbi request reprint Nervous system Lyme disease
    J J Halperin
    Department of Neurology, North Shore University Hospital, Manhasset, NY 11030, USA
    J Neurol Sci 153:182-91. 1998
    ..Oral treatment with doxycycline has been shown to be effective in meningitis. In more serious cases two to four week courses of parenteral ceffriaxone or cefotaxime are effective in the vast majority of patients...
  16. ncbi request reprint Is neuroborreliosis a medical emergency?
    John J Halperin
    NYU School of Medicine, Great Neck, NY, USA
    Neurocrit Care 4:260-6. 2006
    ..Knowing when to consider this spirochetosis in the differential diagnosis requires an understanding of its true clinical spectrum, and of an appropriate diagnostic and therapeutic approach...
  17. ncbi request reprint Central nervous system Lyme disease
    John J Halperin
    Department of Neurology, North Shore University Hospital, Manhasset, NY 11030, USA
    Curr Neurol Neurosci Rep 5:446-52. 2005
    ..Several well-performed studies have clearly shown that prolonged antimicrobial treatment of "post-Lyme disease" is ineffective. Diagnosis and treatment of Lyme disease continue to improve...
  18. ncbi request reprint Lyme disease and the peripheral nervous system
    John J Halperin
    Department of Neurology, North Shore University Hospital, 300 Community Drive, Manhasset, New York 11030, USA
    Muscle Nerve 28:133-43. 2003
    ..The mechanism underlying these neuropathies remains unclear, although interactions between anti-Borrelia antibodies and several peripheral nerve constituent molecules raise intriguing possibilities...
  19. ncbi request reprint Nervous system lyme disease: diagnosis and treatment
    John J Halperin
    Department of Neurosciences, Atlantic Neuroscience Institute, Summit, NJ, USA
    Rev Neurol Dis 6:4-12. 2009
    ..Long-term antibiotic treatment does not provide any additional lasting improvement, but it is frequently associated with significant morbidity...
  20. doi request reprint Oral doxycycline for neuroborreliosis
    Gary P Wormser
    Lancet Neurol 7:665-6. 2008