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| J J HalperinSummaryAffiliation: Morristown Memorial Hospital Country: USA Publications
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Publications
Nervous system Lyme diseaseJohn J Halperin
Department of Neurosciences, Atlantic Neuroscience Institute and Overlook Hospital, Summit, NJ 07902, USA
Infect Dis Clin North Am 22:261-74, vi. 2008..In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit...
Prolonged Lyme disease treatment: enough is enoughJohn J Halperin
Neurology 70:986-7. 2008
A tale of two spirochetes: lyme disease and syphilisJohn J Halperin
Department of Neurology, Madison Avenue, Mount Sinai School of Medicine, NY, USA
Neurol Clin 28:277-91. 2010....
Common misconceptions about Lyme diseaseJohn J Halperin
Department of Neurosciences, Overlook Medical Center, Atlantic Health System, Summit, NJ 07902, USA
Am J Med 126:264.e1-7. 2013..In this article we review the principal misconceptions, discussing their origins and the best currently available scientific evidence related to each one...
Lyme disease: a multisystem infection that affects the nervous systemJohn J Halperin
Overlook Medical Center, Department of Neurosciences, 99 Beauvoir Ave, Summit, NJ 07902, USA
Continuum (Minneap Minn) 18:1338-50. 2012..This article will enable the reader to diagnose and treat nervous system Lyme disease appropriately...
Nervous system lyme disease: is there a controversy?John J Halperin
Department of Neurosciences, Overlook Hospital and Atlantic Neuroscience Institute, Summit, New Jersey 07902, USA
Semin Neurol 31:317-24. 2011..For some (cerebral vasculitis with stroke, optic neuritis) a few case reports suggest a rare possible causal link...
Neurologic manifestations of lyme diseaseJohn J Halperin
Department of Neurosciences, Overlook Hospital and Atlantic Health, 99 Beauvoir Avenue, Summit, NJ 07902, USA
Curr Infect Dis Rep 13:360-6. 2011..When present as part of Lyme disease, they do not require additional or different treatment...
Diagnosis and treatment of the neuromuscular manifestations of lyme diseaseJohn J Halperin
John J Halperin, MD Atlantic Neuroscience Institute and New York University School of Medicine, Overlook Hospital, 99 Beauvoir Avenue, Summit, NJ 07902, USA
Curr Treat Options Neurol 9:93-100. 2007..This may be equally valid in patients infected with the strains prevalent in the United States, but this remains to be established...
Nervous system Lyme diseaseJ J Halperin
Atlantic Neuroscience Institute, Summit, New Jersey, USA
J R Coll Physicians Edinb 40:248-55. 2010..Treatment with any of several standard regimens of oral or parenteral antimicrobials is highly effective. Prolonged treatment beyond four weeks is rarely if ever warranted, and carries significant risk...
Nervous system Lyme diseaseJ J Halperin
Department of Neurology, North Shore University Hospital, Manhasset, NY 11030, USA
J Neurol Sci 153:182-91. 1998..Oral treatment with doxycycline has been shown to be effective in meningitis. In more serious cases two to four week courses of parenteral ceffriaxone or cefotaxime are effective in the vast majority of patients...
Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of NeurologyJ J Halperin
Department of Neurosciences, Overlook Hospital, NYU School of Medicine, Summit, NJ, USA
Neurology 69:91-102. 2007..Three questions were addressed: 1) Which antimicrobial agents are effective? 2) Are different regimens preferred for different manifestations of nervous system Lyme disease? 3) What duration of therapy is needed?..
Is neuroborreliosis a medical emergency?John J Halperin
NYU School of Medicine, Great Neck, NY, USA
Neurocrit Care 4:260-6. 2006..Knowing when to consider this spirochetosis in the differential diagnosis requires an understanding of its true clinical spectrum, and of an appropriate diagnostic and therapeutic approach...
Nervous system lyme disease: diagnosis and treatmentJohn J Halperin
Department of Neurosciences, Atlantic Neuroscience Institute, Summit, NJ, USA
Rev Neurol Dis 6:4-12. 2009..Long-term antibiotic treatment does not provide any additional lasting improvement, but it is frequently associated with significant morbidity...
Central nervous system Lyme diseaseJohn J Halperin
Department of Neurology, North Shore University Hospital, Manhasset, NY 11030, USA
Curr Neurol Neurosci Rep 5:446-52. 2005..Several well-performed studies have clearly shown that prolonged antimicrobial treatment of "post-Lyme disease" is ineffective. Diagnosis and treatment of Lyme disease continue to improve...
Lyme disease and the peripheral nervous systemJohn J Halperin
Department of Neurology, North Shore University Hospital, 300 Community Drive, Manhasset, New York 11030, USA
Muscle Nerve 28:133-43. 2003..The mechanism underlying these neuropathies remains unclear, although interactions between anti-Borrelia antibodies and several peripheral nerve constituent molecules raise intriguing possibilities...
Oral doxycycline for neuroborreliosisGary P Wormser
Lancet Neurol 7:665-6. 2008
