Nana O Wilson

Summary

Affiliation: Morehouse School of Medicine
Country: USA

Publications

  1. pmc Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria
    Nana O Wilson
    Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
    PLoS ONE 8:e60898. 2013
  2. pmc Pregnancy outcomes among patients with sickle cell disease at Korle-Bu Teaching Hospital, Accra, Ghana: retrospective cohort study
    Nana O Wilson
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, GA 30310, USA
    Am J Trop Med Hyg 86:936-42. 2012
  3. pmc Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India
    Vidhan Jain
    Regional Medical Research Center for Tribals ICMR, Nagpur Road, Garha, 482003 Jabalpur, Madhya Pradesh, India
    Malar J 10:383. 2011
  4. pmc Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India
    Vidhan Jain
    National Institute of Malaria Research ICMR, Jabalpur, India
    Malar J 7:83. 2008
  5. pmc Detection of Plasmodium falciparum histidine-rich protein II in saliva of malaria patients
    Nana O Wilson
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 78:733-5. 2008
  6. pmc Intermittent preventive treatment with sulfadoxine-pyrimethamine against malaria and anemia in pregnant women
    Nana O Wilson
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 85:12-21. 2011
  7. pmc CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications
    Mingli Liu
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Cytokine Growth Factor Rev 22:121-30. 2011
  8. pmc Soluble factors from Plasmodium falciparum-infected erythrocytes induce apoptosis in human brain vascular endothelial and neuroglia cells
    Nana O Wilson
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
    Mol Biochem Parasitol 162:172-6. 2008
  9. ncbi Neuregulin-1 attenuates mortality associated with experimental cerebral malaria
    Wesley Solomon
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, USA
    J Neuroinflammation 11:9. 2014
  10. pmc Potential serological biomarkers of cerebral malaria
    Naomi W Lucchi
    Atlanta Research and Education Foundation, Decatur, GA, USA
    Dis Markers 31:327-35. 2011

Collaborators

Detail Information

Publications17

  1. pmc Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria
    Nana O Wilson
    Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
    PLoS ONE 8:e60898. 2013
    ..05. Thus, adjunctively reducing CXCL10 levels and inflammation by atorvastatin treatment during anti-malarial therapy may represent a novel approach to treating CM patients...
  2. pmc Pregnancy outcomes among patients with sickle cell disease at Korle-Bu Teaching Hospital, Accra, Ghana: retrospective cohort study
    Nana O Wilson
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, GA 30310, USA
    Am J Trop Med Hyg 86:936-42. 2012
    ..Improved maternal and fetal outcomes in Ghanaian women with SCD can be achieved through effective intervention by health care providers with thorough knowledge about predisposing factors toward adverse outcomes...
  3. pmc Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India
    Vidhan Jain
    Regional Medical Research Center for Tribals ICMR, Nagpur Road, Garha, 482003 Jabalpur, Madhya Pradesh, India
    Malar J 10:383. 2011
    ....
  4. pmc Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India
    Vidhan Jain
    National Institute of Malaria Research ICMR, Jabalpur, India
    Malar J 7:83. 2008
    ....
  5. pmc Detection of Plasmodium falciparum histidine-rich protein II in saliva of malaria patients
    Nana O Wilson
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 78:733-5. 2008
    ..The specificity was 100% with no false positive for both plasma and saliva when compared with blood smear. Thus, rapid detection of PfHRP II antigen in saliva may be a useful non-invasive and cost-effective malaria diagnostic technique...
  6. pmc Intermittent preventive treatment with sulfadoxine-pyrimethamine against malaria and anemia in pregnant women
    Nana O Wilson
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 85:12-21. 2011
    ..18, 95% confidence interval = 0.08-0.37) and anemia (odds ratio = 0.20, 95% confidence interval = 0.12-0.34) remained significant. The recommended IPTp-SP regimen is useful in preventing malaria and anemia among pregnant women in Ghana...
  7. pmc CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications
    Mingli Liu
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Cytokine Growth Factor Rev 22:121-30. 2011
    ..The potential utilization of CXCL10 as a therapeutic target for infectious diseases is discussed...
  8. pmc Soluble factors from Plasmodium falciparum-infected erythrocytes induce apoptosis in human brain vascular endothelial and neuroglia cells
    Nana O Wilson
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
    Mol Biochem Parasitol 162:172-6. 2008
    ....
  9. ncbi Neuregulin-1 attenuates mortality associated with experimental cerebral malaria
    Wesley Solomon
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, USA
    J Neuroinflammation 11:9. 2014
    ....
  10. pmc Potential serological biomarkers of cerebral malaria
    Naomi W Lucchi
    Atlanta Research and Education Foundation, Decatur, GA, USA
    Dis Markers 31:327-35. 2011
    ..This search revealed a paucity of usable biomarkers for CM management. We propose three main areas in which researchers can attempt to identify CM biomarkers: 1) early biomarkers, 2) diagnostic biomarkers and 3) prognostic biomarkers...
  11. pmc STAT3 regulates MMP3 in heme-induced endothelial cell apoptosis
    Mingli Liu
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia, USA
    PLoS ONE 8:e71366. 2013
    ....
  12. pmc Elevated IL-1α and CXCL10 serum levels occur in patients with homozygous sickle cell disease and a history of acute splenic sequestration
    Adel Driss
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, USA
    Dis Markers 32:295-300. 2012
    ..These observations are consistent with acute splenic sequestration having a distinct phenotype which may be helpful in predicting those at risk of this complication and suggest that the mechanism of these differences merit further study...
  13. pmc Plasma interleukin-1beta concentration is associated with stroke in sickle cell disease
    Kwaku Asare
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    Cytokine 49:39-44. 2010
    ..This result demonstrates a strong association of systemic inflammation with stroke development in HbSS via moderately increased plasma IL-1beta concentration, which is furthermore associated with a decreased likelihood of stroke in HbSS...
  14. pmc Genetic polymorphisms linked to susceptibility to malaria
    Adel Driss
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia, USA
    Malar J 10:271. 2011
    ....
  15. pmc CXCL4 and CXCL10 predict risk of fatal cerebral malaria
    Nana O Wilson
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia 30310, USA
    Dis Markers 30:39-49. 2011
    ..0001) with an area under the curve (AUC)=1. These results suggest that CXCL4 and CXCL10 play a prominent role in pathogenesis of CM associated death and may be used as functional or surrogate biomarkers for predicting CM severity...
  16. pmc Plasmodium berghei ANKA infection increases Foxp3, IL-10 and IL-2 in CXCL-10 deficient C57BL/6 mice
    Bismark Y Sarfo
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Drive, South West, Atlanta Georgia, GA 30310, USA
    Malar J 10:69. 2011
    ..Interleukin-2 (IL-2), a pro-inflammatory cytokine implicated in malaria pathogenesis has also been shown to be a key regulator of Foxp3. However the role of Foxp3 in resistant murine CM is not well understood...
  17. pmc Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children
    Henry B Armah
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia, USA
    Malar J 6:147. 2007
    ..Identification of prognostic markers that can predict CM severity will enable development of better intervention...