Research Topics
Genomes and Genes | Jacqueline M HibbertSummaryAffiliation: Morehouse School of Medicine Country: USA Publications
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Publications
Proinflammatory cytokines and the hypermetabolism of children with sickle cell diseaseJacqueline M Hibbert
Microbiology Biochemistry Immunology Pediatrics, Morehouse School of Medicine, 720 Westview Drive, S W, Atlanta, Georgia 30310 1495, USA
Exp Biol Med (Maywood) 230:68-74. 2005....
Erythropoiesis and myocardial energy requirements contribute to the hypermetabolism of childhood sickle cell anemiaJacqueline M Hibbert
Department of Biochemistry, Morehouse School of Medicine, Atlanta, GA, USA
J Pediatr Gastroenterol Nutr 43:680-7. 2006..We hypothesized that an elevated hemoglobin synthesis rate (SynHb) and myocardial oxygen consumption (MVO2) contribute to the excess protein and energy metabolism reported in children with sickle cell anemia...
Plasma BDNF and PDGF-AA levels are associated with high TCD velocity and stroke in children with sickle cell anemiaHyacinth I Hyacinth
Genomics and Hemoglobinopathies Training Program, Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA, USA
Cytokine 60:302-8. 2012..Stroke incidence and high TCD velocity were associated with elevated BDNF and PDGF-AA. These findings suggest a role for BDNF and PDGF-AA in the patho-physiological mechanism of cerebrovascular disease in SCA...
Elevated IL-1α and CXCL10 serum levels occur in patients with homozygous sickle cell disease and a history of acute splenic sequestrationAdel Driss
Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, USA
Dis Markers 32:295-300. 2012..These observations are consistent with acute splenic sequestration having a distinct phenotype which may be helpful in predicting those at risk of this complication and suggest that the mechanism of these differences merit further study...
Pregnancy outcomes among patients with sickle cell disease at Korle-Bu Teaching Hospital, Accra, Ghana: retrospective cohort studyNana O Wilson
Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, GA 30310, USA
Am J Trop Med Hyg 86:936-42. 2012..Improved maternal and fetal outcomes in Ghanaian women with SCD can be achieved through effective intervention by health care providers with thorough knowledge about predisposing factors toward adverse outcomes...
Plasma interleukin-1beta concentration is associated with stroke in sickle cell diseaseKwaku Asare
Morehouse School of Medicine, Atlanta, GA 30310, USA
Cytokine 49:39-44. 2010..This result demonstrates a strong association of systemic inflammation with stroke development in HbSS via moderately increased plasma IL-1beta concentration, which is furthermore associated with a decreased likelihood of stroke in HbSS...
C-reactive protein and interleukin-6 are decreased in transgenic sickle cell mice fed a high protein dietDavid R Archer
Emory University School of Medicine and the Aflac Cancer Center and Blood Disorders Service, Atlanta, GA 30322, USA
J Nutr 138:1148-52. 2008..Dietary L-arginine availability was investigated as a possible mechanism for increased nitric oxide production and consequent reduced inflammation...
Heme mediated STAT3 activation in severe malariaMingli Liu
Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
PLoS ONE 7:e34280. 2012..We therefore tested the hypothesis that these factors share common signaling pathways and may be mutually regulated...
Genetic polymorphisms linked to susceptibility to malariaAdel Driss
Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia, USA
Malar J 10:271. 2011....
CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implicationsMingli Liu
Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
Cytokine Growth Factor Rev 22:121-30. 2011..The potential utilization of CXCL10 as a therapeutic target for infectious diseases is discussed...
