Research Topics
| David A J MooreSummaryCountry: USA Publications
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Detail Information
Publications
La cuerda dulce--a tolerability and acceptability study of a novel approach to specimen collection for diagnosis of paediatric pulmonary tuberculosisFelicia Chow
Asociación Benéfica Proyectos en Informática, Salud, Medicina, y Agricultura AB PRISMA, Lima, Peru
BMC Infect Dis 6:67. 2006....- Infrequent MODS TB culture cross-contamination in a high-burden resource-poor settingDavid A J Moore
Department of Infectious Diseases and Immunity, Imperial College London Wellcome Centre for Clinical Tropical Medicine, W12 0NN London, UK
Diagn Microbiol Infect Dis 56:35-43. 2006..Low rates of cross-contamination are achievable in mycobacterial laboratories in resource-poor settings even when a large proportion of samples are infectious and highly sensitive liquid culture-based diagnostics such as MODS are used... - Microscopic-observation drug-susceptibility assay for the diagnosis of TBDavid A J Moore
Department of Infectious Diseases and Immunity and the Wellcome Centre for Clinical Tropical Medicine, Imperial College London, Faculty of Medicine Hammersmith Campus, London, United Kingdom
N Engl J Med 355:1539-50. 2006.... - Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmissionA Roderick Escombe
Department of Infectious Diseases and Immunity, Imperial College London, UK
PLoS Med 6:e43. 2009..We evaluated the efficacy of upper-room ultraviolet (UV) lights and negative air ionization for preventing airborne TB transmission using a guinea pig air-sampling model to measure the TB infectiousness of ward air... - The infectiousness of tuberculosis patients coinfected with HIVA Roderick Escombe
Department of Infectious Diseases and Immunity, Imperial College London, United Kingdom
PLoS Med 5:e188. 2008..Recently we recreated this model in Lima, Perú, and in this paper we report the use of molecular fingerprinting to investigate patient infectiousness in the current era of HIV infection and multidrug-resistant (MDR) TB... - The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling modelA Roderick Escombe
Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom
Clin Infect Dis 44:1349-57. 2007..We created an in vivo air sampling model to study airborne transmission of tuberculosis from patients coinfected with human immunodeficiency virus (HIV) and to evaluate environmental control measures... - Solar disinfection of MODS mycobacterial cultures in resource-poor settingsRuvandhi Nathavitharana
Department of Infectious Diseases and Immunity and Wellcome Centre for Clinical Tropical Medicine, Faculty of Medicine, Imperial College London, London, United Kingdom
PLoS ONE 2:e1100. 2007..We investigated the use of a simple solar cooker for the sterilization of mycobacterial broth cultures from the microscopic observation drug susceptibility assay (MODS)... - Alternative methods of diagnosing drug resistance--what can they do for me?David A J Moore
Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Infect Dis 204:S1110-9. 2011..We review the bewildering array of choices facing TB program directors and attempt to provide objective information to help in deciding what tools may be best suited to different environments... - Natural ventilation for the prevention of airborne contagionA Roderick Escombe
Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom
PLoS Med 4:e68. 2007..Natural ventilation may offer a low-cost alternative. Our objective was to investigate the rates, determinants, and effects of natural ventilation in health care settings... - Improved diagnosis of pleural tuberculosis using the microscopic- observation drug-susceptibility techniqueMarco Tovar
Departamento de Microbiologia, Facultad de Ciencias, Universidad Peruana Cayetano Heredia, Lima, Peru
Clin Infect Dis 46:909-12. 2008..51%; time to diagnosis, 11 days vs. 24 days; P < .001). The MODS technique is inexpensive, allows drug-susceptibility testing, and is a considerably improved diagnostic method for pleural tuberculosis... 
Improved recovery of Mycobacterium tuberculosis from children using the microscopic observation drug susceptibility methodRichard A Oberhelman
Department of Tropical Medicine, Tulane School of Public Health and Tropical Medicine, 1440 Canal St, SL 29, New Orleans, Louisiana 70112, USA
Pediatrics 118:e100-6. 2006....- Recent tuberculosis advances in Latin AmericaTom Pelly
A. B. PRISMA, Lima, Peru
Curr Opin Infect Dis 17:397-403. 2004..The need for rapid, affordable tests for tuberculosis diagnosis, and for easy drug sensitivity testing is also evident. Finally, improving treatment success is achievable even in the resource poor setting... - Microscopic observation drug susceptibility assay, a rapid, reliable diagnostic test for multidrug-resistant tuberculosis suitable for use in resource-poor settingsDavid A J Moore
Laboratorio de Investigación de Enfermedades Infecciosas, Universidad Peruana Cayetano Heredia, San Martin de Porras, Lima, Peru
J Clin Microbiol 42:4432-7. 2004..A comprehensive prospective evaluation of MODS is under way in Perú, and independent validation in nonresearch laboratories should be undertaken at the earliest opportunity... - Diagnosis of smear-negative tuberculosis in people with HIV/AIDSDavid A J Moore
Lancet 370:1033-4. 2007 - Diagnosis of sputum-scarce HIV-associated pulmonary tuberculosis in Lima, PeruDaniel Vargas
, Salud, Medicina, y Agricultura, Lima, Peru
Lancet 365:150-2. 2005..03). These preliminary data suggest that the string test is safe and effective for retrieval of useful clinical specimens for diagnosis of pulmonary tuberculosis, and is at least as sensitive as sputum induction... - Tuberculosis in the developing world: recent advances in diagnosis with special consideration of extensively drug-resistant tuberculosisLouis Grandjean
Department of Paediatric Infectious Diseases, St Mary s Hospital Campus, UK
Curr Opin Infect Dis 21:454-61. 2008.... - Inter- and intra-assay reproducibility of microplate Alamar blue assay results for isoniazid, rifampicin, ethambutol, streptomycin, ciprofloxacin, and capreomycin drug susceptibility testing of Mycobacterium tuberculosisBrian Leonard
Laboratorio de Investigación de Enfermedades Infecciosas, Facultad de Ciencias y Filosofia, Universidad Peruana Cayetano Heredia, Av Honorio Delgado No 430, San Martin de Porras, Lima 31, Peru
J Clin Microbiol 46:3526-9. 2008..Between 1.2 and 8.5% of paired MICs differed by more than one twofold dilution, resulting in discordant susceptible-resistant designations at frequencies between 0.6% (rifampin) and 18.9% (ethambutol)... - Postmortem findings and opportunistic infections in HIV-positive patients from a public hospital in PeruDominique Eza
Departamento de Laboratorio y Anatomía Patológica, Hospital Nacional Dos de Mayo, Parque Historia de la Medicina Peruana s n, Altura de Cuadra 13 Avenida Grau, Lima 1, Peru
Pathol Res Pract 202:767-75. 2006.... - Future prospects for the MODS assay in multidrug-resistant tuberculosis diagnosisDavid A J Moore
Future Microbiol 2:97-101. 2007 - Does traditional medicine use hamper efforts at tuberculosis control in urban Peru?Clarissa C Oeser
Asociacion Benefica PRISMA, Lima, Peru
Am J Trop Med Hyg 73:571-5. 2005..01). We thus found no evidence that use of traditional remedies has an appreciable effect on diagnostic delay in Lima... - High rates of tuberculosis in end-stage renal failure: the impact of international migrationDavid A J Moore
Dept. of Infectious Diseases, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London W12 0NN, UK
Emerg Infect Dis 8:77-8. 2002..We recommend enhanced vigilance and screening of such patients, both to reduce illness and death and to prevent nosocomial spread of TB among susceptible persons...