David A J Moore

Summary

Country: USA

Publications

  1. pmc La cuerda dulce--a tolerability and acceptability study of a novel approach to specimen collection for diagnosis of paediatric pulmonary tuberculosis
    Felicia Chow
    Asociación Benéfica Proyectos en Informática, Salud, Medicina, y Agricultura AB PRISMA, Lima, Peru
    BMC Infect Dis 6:67. 2006
  2. pmc Infrequent MODS TB culture cross-contamination in a high-burden resource-poor setting
    David A J Moore
    Department of Infectious Diseases and Immunity, Imperial College London Wellcome Centre for Clinical Tropical Medicine, W12 0NN London, UK
    Diagn Microbiol Infect Dis 56:35-43. 2006
  3. pmc Microscopic-observation drug-susceptibility assay for the diagnosis of TB
    David A J Moore
    Department of Infectious Diseases and Immunity and the Wellcome Centre for Clinical Tropical Medicine, Imperial College London, Faculty of Medicine Hammersmith Campus, London, United Kingdom
    N Engl J Med 355:1539-50. 2006
  4. pmc Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmission
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, UK
    PLoS Med 6:e43. 2009
  5. pmc The infectiousness of tuberculosis patients coinfected with HIV
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, United Kingdom
    PLoS Med 5:e188. 2008
  6. pmc The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom
    Clin Infect Dis 44:1349-57. 2007
  7. pmc Solar disinfection of MODS mycobacterial cultures in resource-poor settings
    Ruvandhi Nathavitharana
    Department of Infectious Diseases and Immunity and Wellcome Centre for Clinical Tropical Medicine, Faculty of Medicine, Imperial College London, London, United Kingdom
    PLoS ONE 2:e1100. 2007
  8. doi request reprint Transmission of Multidrug-Resistant and Drug-Susceptible Tuberculosis within Households: A Prospective Cohort Study
    Louis Grandjean
    Wellcome Centre for Clinical Tropical Medicine, Imperial College London, London, United Kingdom Universidad Peruana Cayetano Heredia, Lima, Peru TB Centre, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Med 12:e1001843; discussion e1001843. 2015
  9. doi request reprint The Association between Mycobacterium Tuberculosis Genotype and Drug Resistance in Peru
    Louis Grandjean
    Wellcome Centre for Clinical Tropical Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London, United Kingdom London School of Hygiene and Tropical Medicine, TB Centre and Department of Clinical Research, Keppel St, London, United Kingdom Laboratorio de Investigacion y Desarrollo, Universidad Peruana Cayetano Heredia, San Martin de Porres, Lima, Peru
    PLoS ONE 10:e0126271. 2015
  10. pmc Alternative methods of diagnosing drug resistance--what can they do for me?
    David A J Moore
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 204:S1110-9. 2011

Collaborators

Detail Information

Publications26

  1. pmc La cuerda dulce--a tolerability and acceptability study of a novel approach to specimen collection for diagnosis of paediatric pulmonary tuberculosis
    Felicia Chow
    Asociación Benéfica Proyectos en Informática, Salud, Medicina, y Agricultura AB PRISMA, Lima, Peru
    BMC Infect Dis 6:67. 2006
    ....
  2. pmc Infrequent MODS TB culture cross-contamination in a high-burden resource-poor setting
    David A J Moore
    Department of Infectious Diseases and Immunity, Imperial College London Wellcome Centre for Clinical Tropical Medicine, W12 0NN London, UK
    Diagn Microbiol Infect Dis 56:35-43. 2006
    ..Low rates of cross-contamination are achievable in mycobacterial laboratories in resource-poor settings even when a large proportion of samples are infectious and highly sensitive liquid culture-based diagnostics such as MODS are used...
  3. pmc Microscopic-observation drug-susceptibility assay for the diagnosis of TB
    David A J Moore
    Department of Infectious Diseases and Immunity and the Wellcome Centre for Clinical Tropical Medicine, Imperial College London, Faculty of Medicine Hammersmith Campus, London, United Kingdom
    N Engl J Med 355:1539-50. 2006
    ....
  4. pmc Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmission
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, UK
    PLoS Med 6:e43. 2009
    ..We evaluated the efficacy of upper-room ultraviolet (UV) lights and negative air ionization for preventing airborne TB transmission using a guinea pig air-sampling model to measure the TB infectiousness of ward air...
  5. pmc The infectiousness of tuberculosis patients coinfected with HIV
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, United Kingdom
    PLoS Med 5:e188. 2008
    ..Recently we recreated this model in Lima, Perú, and in this paper we report the use of molecular fingerprinting to investigate patient infectiousness in the current era of HIV infection and multidrug-resistant (MDR) TB...
  6. pmc The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom
    Clin Infect Dis 44:1349-57. 2007
    ..We created an in vivo air sampling model to study airborne transmission of tuberculosis from patients coinfected with human immunodeficiency virus (HIV) and to evaluate environmental control measures...
  7. pmc Solar disinfection of MODS mycobacterial cultures in resource-poor settings
    Ruvandhi Nathavitharana
    Department of Infectious Diseases and Immunity and Wellcome Centre for Clinical Tropical Medicine, Faculty of Medicine, Imperial College London, London, United Kingdom
    PLoS ONE 2:e1100. 2007
    ..We investigated the use of a simple solar cooker for the sterilization of mycobacterial broth cultures from the microscopic observation drug susceptibility assay (MODS)...
  8. doi request reprint Transmission of Multidrug-Resistant and Drug-Susceptible Tuberculosis within Households: A Prospective Cohort Study
    Louis Grandjean
    Wellcome Centre for Clinical Tropical Medicine, Imperial College London, London, United Kingdom Universidad Peruana Cayetano Heredia, Lima, Peru TB Centre, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Med 12:e1001843; discussion e1001843. 2015
    ..To estimate the relative fitness of drug-resistant tuberculosis cases, we compared the incidence of tuberculosis disease among the household contacts of MDRTB index patients to that among the contacts of drug-susceptible index patients...
  9. doi request reprint The Association between Mycobacterium Tuberculosis Genotype and Drug Resistance in Peru
    Louis Grandjean
    Wellcome Centre for Clinical Tropical Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London, United Kingdom London School of Hygiene and Tropical Medicine, TB Centre and Department of Clinical Research, Keppel St, London, United Kingdom Laboratorio de Investigacion y Desarrollo, Universidad Peruana Cayetano Heredia, San Martin de Porres, Lima, Peru
    PLoS ONE 10:e0126271. 2015
    ....
  10. pmc Alternative methods of diagnosing drug resistance--what can they do for me?
    David A J Moore
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 204:S1110-9. 2011
    ..We review the bewildering array of choices facing TB program directors and attempt to provide objective information to help in deciding what tools may be best suited to different environments...
  11. doi request reprint Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance
    Daniela E Kirwan
    Department of Medical Microbiology, St George s Hospital, London, United Kingdom Infectious Diseases and Immunity, Imperial College London, London, United Kingdom
    J Clin Microbiol 54:185-9. 2016
    ..Despite its lower sensitivity than that of other methods, its faster results and simultaneous DST are advantageous in resource-poor settings, supporting the incorporation of MODS into diagnostic algorithms for extrapulmonary TB. ..
  12. pmc A field evaluation of the Hardy TB MODS Kit™ for the rapid phenotypic diagnosis of tuberculosis and multi-drug resistant tuberculosis
    Laura Martin
    Laboratorio de Investigación en Enfermedades Infecciosas, Universidad Peruana Cayetano Heredia, Lima, Peru Wellcome Centre for Clinical Tropical Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom
    PLoS ONE 9:e107258. 2014
    ..Here we report the results from a large-scale field evaluation of the MODS kit in a government service laboratory...
  13. doi request reprint Reaching out to take on TB in Somalia
    David A J Moore
    London School of Hygiene and Tropical Medicine TB Centre, London, WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 108:4-5. 2014
    ..In the extremely challenging environment of Somalia, multiple partners are making headway though collaboration and innovation...
  14. pmc Natural ventilation for the prevention of airborne contagion
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom
    PLoS Med 4:e68. 2007
    ..Natural ventilation may offer a low-cost alternative. Our objective was to investigate the rates, determinants, and effects of natural ventilation in health care settings...
  15. pmc Improved diagnosis of pleural tuberculosis using the microscopic- observation drug-susceptibility technique
    Marco Tovar
    Departamento de Microbiologia, Facultad de Ciencias, Universidad Peruana Cayetano Heredia, Lima, Peru
    Clin Infect Dis 46:909-12. 2008
    ..51%; time to diagnosis, 11 days vs. 24 days; P < .001). The MODS technique is inexpensive, allows drug-susceptibility testing, and is a considerably improved diagnostic method for pleural tuberculosis...
  16. ncbi request reprint Diagnosis of smear-negative tuberculosis in people with HIV/AIDS
    David A J Moore
    Lancet 370:1033-4. 2007
  17. pmc Recent tuberculosis advances in Latin America
    Tom Pelly
    A B PRISMA, Lima, Peru
    Curr Opin Infect Dis 17:397-403. 2004
    ..Tuberculosis kills more people than any other infection. Despite advances in diagnostic methods and greater understanding of the reasons for treatment failure, tuberculosis remains common throughout Latin America...
  18. pmc Microscopic observation drug susceptibility assay, a rapid, reliable diagnostic test for multidrug-resistant tuberculosis suitable for use in resource-poor settings
    David A J Moore
    Laboratorio de Investigación de Enfermedades Infecciosas, Universidad Peruana Cayetano Heredia, San Martin de Porras, Lima, Peru
    J Clin Microbiol 42:4432-7. 2004
    ..A comprehensive prospective evaluation of MODS is under way in Perú, and independent validation in nonresearch laboratories should be undertaken at the earliest opportunity...
  19. pmc Diagnosis of sputum-scarce HIV-associated pulmonary tuberculosis in Lima, Peru
    Daniel Vargas
    Asociación Benéfica Proyectos en Informática, Salud, Medicina, y Agricultura, Lima, Peru
    Lancet 365:150-2. 2005
    ..03). These preliminary data suggest that the string test is safe and effective for retrieval of useful clinical specimens for diagnosis of pulmonary tuberculosis, and is at least as sensitive as sputum induction...
  20. ncbi request reprint Improved recovery of Mycobacterium tuberculosis from children using the microscopic observation drug susceptibility method
    Richard A Oberhelman
    Department of Tropical Medicine, Tulane School of Public Health and Tropical Medicine, 1440 Canal St, SL 29, New Orleans, Louisiana 70112, USA
    Pediatrics 118:e100-6. 2006
    ....
  21. pmc Postmortem findings and opportunistic infections in HIV-positive patients from a public hospital in Peru
    Dominique Eza
    Departamento de Laboratorio y Anatomía Patológica, Hospital Nacional Dos de Mayo, Parque Historia de la Medicina Peruana s n, Altura de Cuadra 13 Avenida Grau, Lima 1, Peru
    Pathol Res Pract 202:767-75. 2006
    ....
  22. ncbi request reprint Does traditional medicine use hamper efforts at tuberculosis control in urban Peru?
    Clarissa C Oeser
    Asociacion Benefica PRISMA, Lima, Peru
    Am J Trop Med Hyg 73:571-5. 2005
    ..01). We thus found no evidence that use of traditional remedies has an appreciable effect on diagnostic delay in Lima...
  23. ncbi request reprint Future prospects for the MODS assay in multidrug-resistant tuberculosis diagnosis
    David A J Moore
    Future Microbiol 2:97-101. 2007
  24. pmc Tuberculosis in the developing world: recent advances in diagnosis with special consideration of extensively drug-resistant tuberculosis
    Louis Grandjean
    Department of Paediatric Infectious Diseases, St Mary s Hospital Campus, UK
    Curr Opin Infect Dis 21:454-61. 2008
    ....
  25. pmc Inter- and intra-assay reproducibility of microplate Alamar blue assay results for isoniazid, rifampicin, ethambutol, streptomycin, ciprofloxacin, and capreomycin drug susceptibility testing of Mycobacterium tuberculosis
    Brian Leonard
    Laboratorio de Investigación de Enfermedades Infecciosas, Facultad de Ciencias y Filosofia, Universidad Peruana Cayetano Heredia, Av Honorio Delgado No 430, San Martin de Porras, Lima 31, Peru
    J Clin Microbiol 46:3526-9. 2008
    ..Between 1.2 and 8.5% of paired MICs differed by more than one twofold dilution, resulting in discordant susceptible-resistant designations at frequencies between 0.6% (rifampin) and 18.9% (ethambutol)...
  26. pmc High rates of tuberculosis in end-stage renal failure: the impact of international migration
    David A J Moore
    Dept of Infectious Diseases, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London W12 0NN, UK
    Emerg Infect Dis 8:77-8. 2002
    ..We recommend enhanced vigilance and screening of such patients, both to reduce illness and death and to prevent nosocomial spread of TB among susceptible persons...