Andrew J Wilson

Summary

Affiliation: Montefiore Medical Center
Country: USA

Publications

  1. ncbi Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction
    Andrew J Wilson
    Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA
    Cancer Res 70:609-20. 2010
  2. ncbi Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    Cancer Res 62:6006-10. 2002
  3. ncbi TR3/Nur77 in colon cancer cell apoptosis
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    Cancer Res 63:5401-7. 2003
  4. ncbi HDAC4 promotes growth of colon cancer cells via repression of p21
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, NY 10467, USA
    Mol Biol Cell 19:4062-75. 2008
  5. ncbi Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis
    John M Mariadason
    Montefiore Medical Cente, Albert Einstein Cancer Center, Bronx, New Yorrk 10467, USA
    Gastroenterology 128:1081-8. 2005
  6. ncbi The intrinsic mitochondrial membrane potential (Deltapsim) is associated with steady-state mitochondrial activity and the extent to which colonic epithelial cells undergo butyrate-mediated growth arrest and apoptosis
    Barbara G Heerdt
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA
    Cancer Res 63:6311-9. 2003
  7. ncbi PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab
    Minaxi Jhawer
    Department of Oncology, Montefiore Medical Center, Albert Einstein Cancer Center, Bronx, NY 10467, USA
    Cancer Res 68:1953-61. 2008
  8. ncbi Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    J Biol Chem 281:13548-58. 2006
  9. ncbi Intestinal epithelial-specific PTEN inactivation results in tumor formation
    Do Sun Byun
    Montefiore Medical Center, Albert Einstein Cancer Center, Bronx, New York, USA
    Am J Physiol Gastrointest Liver Physiol 301:G856-64. 2011
  10. ncbi Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin
    John M Mariadason
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    Cancer Res 63:8791-812. 2003

Collaborators

Detail Information

Publications14

  1. ncbi Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction
    Andrew J Wilson
    Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA
    Cancer Res 70:609-20. 2010
    ..Our findings link HDACi-induced apoptosis to activation of a Spl/Sp3-mediated response that involves derepression of a transcriptional network basally repressed in colon cancer...
  2. ncbi Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    Cancer Res 62:6006-10. 2002
    ..We have described a novel approach for evaluating the effects of chemopreventive agents on the expression of a gene critical in colonic tumorigenesis...
  3. ncbi TR3/Nur77 in colon cancer cell apoptosis
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    Cancer Res 63:5401-7. 2003
    ..Therefore, TR3 translocation from the nucleus may initiate the apoptotic cascade in colon cancer cells by stimulating other cytosolic proapoptotic molecules to associate with mitochondria...
  4. ncbi HDAC4 promotes growth of colon cancer cells via repression of p21
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, NY 10467, USA
    Mol Biol Cell 19:4062-75. 2008
    ..These studies identify HDAC4 as a novel regulator of colon cell proliferation through repression of p21...
  5. ncbi Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis
    John M Mariadason
    Montefiore Medical Cente, Albert Einstein Cancer Center, Bronx, New Yorrk 10467, USA
    Gastroenterology 128:1081-8. 2005
    ..To define the genetic reprogramming that drives intestinal epithelial cell maturation along the crypt-villus axis, enterocytes were sequentially isolated from the villus tip to the crypts of mouse small intestine...
  6. ncbi The intrinsic mitochondrial membrane potential (Deltapsim) is associated with steady-state mitochondrial activity and the extent to which colonic epithelial cells undergo butyrate-mediated growth arrest and apoptosis
    Barbara G Heerdt
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA
    Cancer Res 63:6311-9. 2003
    ....
  7. ncbi PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab
    Minaxi Jhawer
    Department of Oncology, Montefiore Medical Center, Albert Einstein Cancer Center, Bronx, NY 10467, USA
    Cancer Res 68:1953-61. 2008
    ..A priori screening of colon tumors for PTEN expression status and PIK3CA and Ras/BRAF mutation status could help stratify patients likely to benefit from this therapy...
  8. ncbi Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
    Andrew J Wilson
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    J Biol Chem 281:13548-58. 2006
    ....
  9. ncbi Intestinal epithelial-specific PTEN inactivation results in tumor formation
    Do Sun Byun
    Montefiore Medical Center, Albert Einstein Cancer Center, Bronx, New York, USA
    Am J Physiol Gastrointest Liver Physiol 301:G856-64. 2011
    ....
  10. ncbi Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin
    John M Mariadason
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA
    Cancer Res 63:8791-812. 2003
    ....
  11. ncbi Environment-gene interactions in intestinal cancer
    Leonard H Augenlicht
    Department of Oncology, Albert Einstein Cancer Center, Montefiore Hospital, 111 East 210th Street, Bronx, NY 10467, USA
    Eur J Cancer Prev 11:S12-7. 2002
    ..This renders the cells competent to efficiently utilize factors in the intestinal lumen in normal metabolic and signaling pathways that contribute to homeostasis...
  12. ncbi Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors
    Hafid Alazzouzi
    Molecular Oncology and Aging Group, Molecular Biology and Biochemistry Research Center (CIBBIM, Valle Hebron Hospital Research Institute, Barcelona, Spain
    Cancer Res 65:10170-3. 2005
    ....
  13. ncbi Directed denaturation: room temperature and stoichiometric unfolding of cytochrome C by a metalloporphyrin dimer
    Andrew J Wilson
    Department of Chemistry, P.O. Box 208107, 225 Prospect Street, Yale University, New Haven, CT 06520-8107, USA
    J Am Chem Soc 125:4420-1. 2003
    ....
  14. ncbi Abnormal KCNQ1 trafficking influences disease pathogenesis in hereditary long QT syndromes (LQT1)
    Andrew J Wilson
    BHF Laboratories and Department of Medicine, University College London, 5 University Street, London, WC1E 6JJ, UK
    Cardiovasc Res 67:476-86. 2005
    ..CONCLUSIONS: Our data revealed that channel trafficking may contribute to the pathogenesis of LQT1...