Sharon R Silbiger

Summary

Affiliation: Montefiore Medical Center
Country: USA

Publications

  1. ncbi request reprint The role of gender in the progression of renal disease
    Sharon R Silbiger
    Department of Medicine, Division of Nephrology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA
    Adv Ren Replace Ther 10:3-14. 2003
  2. doi request reprint Gender and human chronic renal disease
    Sharon Silbiger
    Division of Nephrology, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, New York 10467, USA
    Gend Med 5:S3-S10. 2008
  3. doi request reprint Raging hormones: gender and renal disease
    Sharon R Silbiger
    Department of Medicine, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Kidney Int 79:382-4. 2011
  4. ncbi request reprint Effects of sex on renal structure
    Joel Neugarten
    Renal Division, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA
    Nephron 90:139-44. 2002
  5. doi request reprint Raloxifene, a selective estrogen receptor modulator, is renoprotective: a post-hoc analysis
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, USA
    Kidney Int 79:241-9. 2011
  6. ncbi request reprint Estradiol upregulates mesangial cell MMP-2 activity via the transcription factor AP-2
    Michael Guccione
    Division of Nephrology, Department of Medicine, Montefiore Medical Center, and the Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Am J Physiol Renal Physiol 282:F164-9. 2002
  7. ncbi request reprint Estradiol reverses TGF-beta1-induced mesangial cell apoptosis by a casein kinase 2-dependent mechanism
    Olivia Negulescu
    Division of Nephrology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Kidney Int 62:1989-98. 2002
  8. ncbi request reprint Estradiol reverses renal injury in Alb/TGF-beta1 transgenic mice
    Joel Blush
    Division of Nephrology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Kidney Int 66:2148-54. 2004

Collaborators

Detail Information

Publications8

  1. ncbi request reprint The role of gender in the progression of renal disease
    Sharon R Silbiger
    Department of Medicine, Division of Nephrology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA
    Adv Ren Replace Ther 10:3-14. 2003
    ..Further investigation into the contribution of gender to renal disease progression may aid us in developing strategies for slowing this pathological process...
  2. doi request reprint Gender and human chronic renal disease
    Sharon Silbiger
    Division of Nephrology, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, New York 10467, USA
    Gend Med 5:S3-S10. 2008
    ..Hormonal manipulation by male or female castration also changes the course of renal disease progression, suggesting direct effects of sex hormones in influencing the course of these maladies...
  3. doi request reprint Raging hormones: gender and renal disease
    Sharon R Silbiger
    Department of Medicine, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Kidney Int 79:382-4. 2011
    ..Doublier and colleagues explore the direct effects of sex hormones on podocyte viability in the ╬▒-estrogen receptor knockout (╬▒ERKO) mouse. They report that testosterone induces, and estradiol inhibits, podocyte damage in this model...
  4. ncbi request reprint Effects of sex on renal structure
    Joel Neugarten
    Renal Division, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA
    Nephron 90:139-44. 2002
    ..Elucidation of the mechanisms responsible for the observed effects of sex on the progression of chronic renal disease requires knowledge of the effects of sex on renal structure...
  5. doi request reprint Raloxifene, a selective estrogen receptor modulator, is renoprotective: a post-hoc analysis
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, USA
    Kidney Int 79:241-9. 2011
    ..Thus, treatment with raloxifene was safe and renoprotective. Clinical trials of raloxifene in post-menopausal women with kidney disease designed to look at kidney outcomes are needed to confirm these findings...
  6. ncbi request reprint Estradiol upregulates mesangial cell MMP-2 activity via the transcription factor AP-2
    Michael Guccione
    Division of Nephrology, Department of Medicine, Montefiore Medical Center, and the Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Am J Physiol Renal Physiol 282:F164-9. 2002
    ..Stimulation of metalloproteinase activity by estradiol may contribute to the protective effect of female gender on renal disease progression...
  7. ncbi request reprint Estradiol reverses TGF-beta1-induced mesangial cell apoptosis by a casein kinase 2-dependent mechanism
    Olivia Negulescu
    Division of Nephrology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Kidney Int 62:1989-98. 2002
    ..We hypothesized that estradiol would reverse TGF-beta1-induced mesangial cell apoptosis by antagonizing the stimulatory effects of TGF-beta1 on casein kinase 2 activity, thereby preventing p53 activation...
  8. ncbi request reprint Estradiol reverses renal injury in Alb/TGF-beta1 transgenic mice
    Joel Blush
    Division of Nephrology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Kidney Int 66:2148-54. 2004
    ..We hypothesized that the ability of estradiol to reverse the effects of TGF-beta underlies gender dimorphism in the progression of chronic renal disease...