Khlebnikov A, Schepetkin I, Kishkentaeva A, Shaimerdenova Z, Atazhanova G, Adekenov S, et al. Inhibition of T Cell Receptor Activation by Semi-Synthetic Sesquiterpene Lactone Derivatives and Molecular Modeling of Their Interaction with Glutathione and Tyrosine Kinase ZAP-70. Molecules. 2019;24: pubmed publisher
..We suggest that natural and/or semi-synthetic SLs with an α -methylene- γ -lactone moiety can specifically target GSH and the kinase site of ZAP-70 and inhibit the initial phases of TCR activation. ..
Utegenova G, Pallister K, Kushnarenko S, Ozek G, Ozek T, Abidkulova K, et al. Chemical Composition and Antibacterial Activity of Essential Oils from Ferula L. Species against Methicillin-Resistant Staphylococcus aureus. Molecules. 2018;23: pubmed publisher
..Overall, these results suggest that the EOs from F. ovina could have potential for use as alternative remedies for the treatment of infectious diseases caused by MRSA. ..
Kouakou K, Schepetkin I, Jun S, Kirpotina L, Yapi A, Khramova D, et al. Immunomodulatory activity of polysaccharides isolated from Clerodendrum splendens: beneficial effects in experimental autoimmune encephalomyelitis. BMC Complement Altern Med. 2013;13:149 pubmed publisher
..However, little is known about the high-molecular weight active components conferring therapeutic properties to these extracts...