John Costerton

Summary

Affiliation: Montana State University
Country: USA

Publications

  1. ncbi request reprint The influence of fluid shear and AICI3 on the material properties of Pseudomonas aeruginosa PAO1 and Desulfovibrio sp. EX265 biofilms
    P Stoodley
    Center for Biofilm Engineering, 366 EPS Bldg Montana State University, Bozeman, MT 59717, USA
    Water Sci Technol 43:113-20. 2001
  2. ncbi request reprint Cystic fibrosis pathogenesis and the role of biofilms in persistent infection
    J W Costerton
    Center for Biofilm Engineering, Montana State University, Bozeman, MT 59717 3980, USA
    Trends Microbiol 9:50-2. 2001
  3. ncbi request reprint Biofilms as complex differentiated communities
    P Stoodley
    Center for Biofilm Engineering, Montana State University, Bozeman 59717, USA
    Annu Rev Microbiol 56:187-209. 2002
  4. pmc The application of biofilm science to the study and control of chronic bacterial infections
    William Costerton
    Center for Biofilm Engineering, Montana State University, Bozeman, Montana 59717 3980, USA
    J Clin Invest 112:1466-77. 2003
  5. pmc Morphological and metabolic responses to starvation by the dissimilatory metal-reducing bacterium Shewanella alga BrY
    F Caccavo
    Center for Biofilm Engineering, Montana State University, Bozeman 59717, USA
    Appl Environ Microbiol 62:4678-82. 1996
  6. ncbi request reprint Can laboratory reference strains mirror "real-world" pathogenesis?
    C A Fux
    Center for Biofilm Engineering, Montana State University, 366 EPS Building P O Box 173980, Bozeman, MT 59717, USA
    Trends Microbiol 13:58-63. 2005
  7. ncbi request reprint Antibiotic resistance of bacteria in biofilms
    P S Stewart
    Center for Biofilm Engineering and Department of Chemical Engineering, Montana State University, Bozeman, MT 59717 3980, USA
    Lancet 358:135-8. 2001
  8. pmc Growth and detachment of cell clusters from mature mixed-species biofilms
    P Stoodley
    Civil Engineering, Montana State University Bozeman, Bozeman, Montana 59717 3980, USA
    Appl Environ Microbiol 67:5608-13. 2001
  9. pmc Ultrasonically controlled release of ciprofloxacin from self-assembled coatings on poly(2-hydroxyethyl methacrylate) hydrogels for Pseudomonas aeruginosa biofilm prevention
    P Norris
    Center for Biofilm Engineering, 366 EPS Building, Montana State University Bozeman, 59717, USA
    Antimicrob Agents Chemother 49:4272-9. 2005
  10. pmc Gene expression in Pseudomonas aeruginosa: evidence of iron override effects on quorum sensing and biofilm-specific gene regulation
    N Bollinger
    Center for Biofilm Engineering, Montana State University, Bozeman, Montana 59717, USA
    J Bacteriol 183:1990-6. 2001

Research Grants

Collaborators

Detail Information

Publications15

  1. ncbi request reprint The influence of fluid shear and AICI3 on the material properties of Pseudomonas aeruginosa PAO1 and Desulfovibrio sp. EX265 biofilms
    P Stoodley
    Center for Biofilm Engineering, 366 EPS Bldg Montana State University, Bozeman, MT 59717, USA
    Water Sci Technol 43:113-20. 2001
    ....
  2. ncbi request reprint Cystic fibrosis pathogenesis and the role of biofilms in persistent infection
    J W Costerton
    Center for Biofilm Engineering, Montana State University, Bozeman, MT 59717 3980, USA
    Trends Microbiol 9:50-2. 2001
    ..These unequivocal data establish this chronic infection of compromised hosts as the archetypal biofilm infection, which is both refractory to antibiotic therapy and barely affected by host defenses...
  3. ncbi request reprint Biofilms as complex differentiated communities
    P Stoodley
    Center for Biofilm Engineering, Montana State University, Bozeman 59717, USA
    Annu Rev Microbiol 56:187-209. 2002
    ..In a holistic sense both biofilm and planktonic phenotypes may be viewed as integrated components of prokaryote life...
  4. pmc The application of biofilm science to the study and control of chronic bacterial infections
    William Costerton
    Center for Biofilm Engineering, Montana State University, Bozeman, Montana 59717 3980, USA
    J Clin Invest 112:1466-77. 2003
    ..We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science and engineering to the clinical management of infectious diseases...
  5. pmc Morphological and metabolic responses to starvation by the dissimilatory metal-reducing bacterium Shewanella alga BrY
    F Caccavo
    Center for Biofilm Engineering, Montana State University, Bozeman 59717, USA
    Appl Environ Microbiol 62:4678-82. 1996
    ..Microbially reduced subsurface materials reduced CrO(4)2-. Starvation of dissimilatory metal-reducing bacteria may provide a means of delivering this metabolism to contaminated subsurface environments for in situ bioremediation...
  6. ncbi request reprint Can laboratory reference strains mirror "real-world" pathogenesis?
    C A Fux
    Center for Biofilm Engineering, Montana State University, 366 EPS Building P O Box 173980, Bozeman, MT 59717, USA
    Trends Microbiol 13:58-63. 2005
    ..It appears that no bacterial strain can truly represent its species. For DNA microarray and proteomic studies, this limitation might be overcome by the summation of individual genomes to produce a species-specific virtual supragenome...
  7. ncbi request reprint Antibiotic resistance of bacteria in biofilms
    P S Stewart
    Center for Biofilm Engineering and Department of Chemical Engineering, Montana State University, Bozeman, MT 59717 3980, USA
    Lancet 358:135-8. 2001
    ..In biofilms, resistance seems to depend on multicellular strategies. We summarise the features of biofilm infections, review emerging mechanisms of resistance, and discuss potential therapies...
  8. pmc Growth and detachment of cell clusters from mature mixed-species biofilms
    P Stoodley
    Civil Engineering, Montana State University Bozeman, Bozeman, Montana 59717 3980, USA
    Appl Environ Microbiol 67:5608-13. 2001
    ..These results have significance in the establishment of an infectious dose and public health risk assessment...
  9. pmc Ultrasonically controlled release of ciprofloxacin from self-assembled coatings on poly(2-hydroxyethyl methacrylate) hydrogels for Pseudomonas aeruginosa biofilm prevention
    P Norris
    Center for Biofilm Engineering, 366 EPS Building, Montana State University Bozeman, 59717, USA
    Antimicrob Agents Chemother 49:4272-9. 2005
    ..The results of these studies may ultimately facilitate the future development of medical devices sensitive to external ultrasonic impulses and capable of treating or preventing biofilm growth via "on-demand" drug release...
  10. pmc Gene expression in Pseudomonas aeruginosa: evidence of iron override effects on quorum sensing and biofilm-specific gene regulation
    N Bollinger
    Center for Biofilm Engineering, Montana State University, Bozeman, Montana 59717, USA
    J Bacteriol 183:1990-6. 2001
    ....
  11. pmc Influence of hydrodynamics and cell signaling on the structure and behavior of Pseudomonas aeruginosa biofilms
    B Purevdorj
    Center for Biofilm Engineering, Montana State University Bozeman, Bozeman, Montana 59717 3980, USA
    Appl Environ Microbiol 68:4457-64. 2002
    ....
  12. pmc Human leukocytes adhere to, penetrate, and respond to Staphylococcus aureus biofilms
    Jeff G Leid
    Department of Cell Biology and Neuroscience, Center for Biofilm Engineering, Montana State University, Bozeman, Montana 59717, USA
    Infect Immun 70:6339-45. 2002
    ..We demonstrate here that under conditions mimicking physiological shear, leukocytes attach, penetrate, and produce cytokines in response to maturing and fully matured S. aureus biofilm...
  13. ncbi request reprint Survival strategies of infectious biofilms
    C A Fux
    Center for Biofilm Engineering, Montana State University, 366 EPS Building P O Box 173980, Bozeman, MT 59717, USA
    Trends Microbiol 13:34-40. 2005
    ..Advances in characterizing the role of stress response genes, quorum sensing and phase variation in stationary-phase planktonic cultures have shed new light on tolerance mechanisms within biofilm communities...
  14. ncbi request reprint Immunology of Staphylococcal biofilm infections in the eye: new tools to study biofilm endophthalmitis
    Jeff G Leid
    Center for Biofilm Engineering, Montana State University, Bozeman, Montana, USA
    DNA Cell Biol 21:405-13. 2002
    ..Additionally, this review highlights some relevant biofilm-immune system interactions and outlines a new in vivo mouse model to explore biofilm-related infections in endophthalmitis...
  15. ncbi request reprint A new procedure allowing the complete removal and prevention of hemodialysis biofilms
    Karine Marion
    Faculte de Pharmacie, EA 3090, Laboratoire de Microbiologie, Lyon, France
    Blood Purif 23:339-48. 2005
    ..The procedure led to the complete detachment of the biomass, both in vitro and in the reality situation. The aim of this procedure is to replace or complete the usual disinfection methods for medical devices...

Research Grants4

  1. Control of Biofilms by Natural Products
    John Costerton; Fiscal Year: 2001
    ..proposed commercial application: not available ..
  2. Control of Biofilms by Natural Products
    John Costerton; Fiscal Year: 2004
    ..The potential market penetration for potent biofilm inhibitors is exemplified by the sheer number of cases in which biofilms cause medical problems. ..
  3. Microbial Biofilms: Systems Biology Affecting Humans and the Environment
    John Costerton; Fiscal Year: 2005
    ..abstract_text> ..