Research Topics
Genomes and Genes | John BerminghamSummaryAffiliation: Montana State University Country: USA Publications
Research Grants
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Detail Information
Publications
Modification of representational difference analysis applied to the isolation of forskolin-regulated genes from Schwann cellsJ R Bermingham
McLaughlin Research Institute, Great Falls, Montana 59405, USA
J Neurosci Res 63:516-24. 2001..The genes that we have identified, including MKP3, a regulator of ERK signaling, and the sphingosine-1-phosphate receptor edg3/lp(B3), may play important roles in mediating Schwann cell differentiation...
Identification of genes that are downregulated in the absence of the POU domain transcription factor pou3f1 (Oct-6, Tst-1, SCIP) in sciatic nerveJohn R Bermingham
McLaughlin Research Institute, Great Falls, Montana 59405, USA
J Neurosci 22:10217-31. 2002..Our results suggest that pou3f1 functions to activate gene expression in the differentiation of myelinating Schwann cells...
Organization and expression of the SLC36 cluster of amino acid transporter genesJohn R Bermingham
McLaughlin Research Institute, 1520 23rd Street South, Great Falls, Montana 59405, USA
Mamm Genome 15:114-25. 2004..SLC36A2 is a candidate gene for 5q-myelodysplastic syndrome, on the basis of its chromosomal location and its expression in bone...
The claw paw mutation reveals a role for Lgi4 in peripheral nerve developmentJohn R Bermingham
McLaughlin Research Institute, 1520 23rd Street South, Great Falls, Montana 59405, USA
Nat Neurosci 9:76-84. 2006..Thus, the abnormalities observed in clp mice are attributable to the loss of Lgi4 function, and they identify Lgi4 as a new component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation...
Research Grants
- Genetic Control of Schwann Cell DifferentiationJohn Bermingham; Fiscal Year: 2009..By understanding how the Lgi4 protein controls Schwann cell development, we will establish new avenues for the treatment of myelin disorders and nerve injury. ..
- Genetic Control of Schwann Cell DifferentiationJohn Bermingham; Fiscal Year: 2007..By understanding how the Lgi4 protein controls Schwann cell development, we will establish new avenues for the treatment of myelin disorders and nerve injury. ..
- GENETIC CONTROL OF SCHWANN CELL MYELINATIONJohn Bermingham; Fiscal Year: 2005..In the fourth Specific Aim, it is proposed to study postnatal functions of Oct-6 in peripheral myelination using mice that lack the gene only in Schwann cells. ..
- Genetic Control of Schwann Cell DifferentiationJOHN RUTLEDGE BERMINGHAM; Fiscal Year: 2011..By understanding how the Lgi4 protein controls Schwann cell development, we will establish new avenues for the treatment of myelin disorders and nerve injury. ..
