Affiliation: Monogram Biosciences
- EGFR over-expression and activation in high HER2, ER negative breast cancer cell line induces trastuzumab resistanceRajiv Dua
Oncology, Monogram Biosciences, 345 Oyster Point Blvd, South San Francisco, CA, USA
Breast Cancer Res Treat 122:685-97. 2010....
- Detection of hepatocyte growth factor (HGF) ligand-c-MET receptor activation in formalin-fixed paraffin embedded specimens by a novel proximity assayRajiv Dua
Research and Development, Oncology, Monogram Biosciences Inc, South San Francisco, California, United States of America
PLoS ONE 6:e15932. 2011..This report describes a novel approach for the detection and quantification of ligand-receptor interactions that can be widely applied to measure receptor activation in FFPE preclinical models and archived FFPE human tissue specimens...
- A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissueYining Shi
Departments of Research and Development, Clinical Research, and Operations, Monogram Biosciences Inc, 345 Oyster Point Boulevard, South San Francisco, CA 94080, USA
Diagn Mol Pathol 18:11-21. 2009..The continuous measure of HER2 protein levels over a broad dynamic range, and the novel HER2 homodimer measure, are presently being assessed as predictive markers for responses to targeted HER2 therapy...