JULIE MENNELLA

Summary

Affiliation: Monell Chemical Senses Center
Country: USA

Publications

  1. pmc Sweet and sour preferences during childhood: role of early experiences
    Djin Gie Liem
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Dev Psychobiol 41:388-95. 2002
  2. pmc Chemosensory factors influencing alcohol perception, preferences, and consumption
    Alexander A Bachmanov
    Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104 3308, USA
    Alcohol Clin Exp Res 27:220-31. 2003
  3. pmc The bad taste of medicines: overview of basic research on bitter taste
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Clin Ther 35:1225-46. 2013
  4. pmc Sensitive period in flavor learning: effects of duration of exposure to formula flavors on food likes during infancy
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Clin Nutr 31:1022-5. 2012
  5. pmc Complementary foods and flavor experiences: setting the foundation
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Ann Nutr Metab 60:40-50. 2012
  6. pmc Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market St, Philadelphia, PA 19104, USA
    BMC Genet 11:60. 2010
  7. ncbi Infant feeding practices and early flavor experiences in Mexican infants: an intra-cultural study
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    J Am Diet Assoc 105:908-15. 2005
  8. pmc Children's hedonic responses to the odors of alcoholic beverages: a window to emotions
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Alcohol 42:249-60. 2008
  9. pmc Genetic and environmental determinants of bitter perception and sweet preferences
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Pediatrics 115:e216-22. 2005
  10. pmc Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Addiction 105:666-75. 2010

Research Grants

Detail Information

Publications51

  1. pmc Sweet and sour preferences during childhood: role of early experiences
    Djin Gie Liem
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Dev Psychobiol 41:388-95. 2002
    ..These data illustrate the wide variety of experiential factors that can influence flavor preferences during childhood...
  2. pmc Chemosensory factors influencing alcohol perception, preferences, and consumption
    Alexander A Bachmanov
    Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104 3308, USA
    Alcohol Clin Exp Res 27:220-31. 2003
    ..Bachmanov and Michael Tordoff); and (6) Human genetic variation in taste: connections with alcohol sensation and intake (Valerie B. Duffy and Linda M. Bartoshuk). The symposium concluded with a general discussion...
  3. pmc The bad taste of medicines: overview of basic research on bitter taste
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Clin Ther 35:1225-46. 2013
    ..Encapsulation of the medicine in pill or tablet form, an effective method for adults to avoid the unpleasant taste, is problematic for children. Many children cannot or will not swallow solid dose forms...
  4. pmc Sensitive period in flavor learning: effects of duration of exposure to formula flavors on food likes during infancy
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Clin Nutr 31:1022-5. 2012
    ..This study aimed to determine the effects of duration of exposure during the sensitive period on a food containing an exemplar of the savory flavor...
  5. pmc Complementary foods and flavor experiences: setting the foundation
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Ann Nutr Metab 60:40-50. 2012
    ..Introducing children repeatedly to individual as well as a variety of fruits and vegetables, both within and between meals, might help them be more accepting of fruits and vegetables, which is difficult to enhance beyond toddlerhood...
  6. pmc Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market St, Philadelphia, PA 19104, USA
    BMC Genet 11:60. 2010
    ..The purpose of this study was to investigate the effect of TAS2R38 haplotypes and age on human bitter taste perception...
  7. ncbi Infant feeding practices and early flavor experiences in Mexican infants: an intra-cultural study
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    J Am Diet Assoc 105:908-15. 2005
    ..We hypothesized that, despite the culinary diversity within Mexico, there would be similar patterns in the types of flavors and foods eaten by mothers and fed to infants...
  8. pmc Children's hedonic responses to the odors of alcoholic beverages: a window to emotions
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Alcohol 42:249-60. 2008
    ..Whether children who associate the odor of alcohol with such emotional contexts display a trajectory toward or against using alcohol to escape remains unknown...
  9. pmc Genetic and environmental determinants of bitter perception and sweet preferences
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Pediatrics 115:e216-22. 2005
    ....
  10. pmc Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Addiction 105:666-75. 2010
    ..Design Between- and within-subject experimental study...
  11. pmc Breastfeeding and smoking: short-term effects on infant feeding and sleep
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market St, Philadelphia, PA 19104 3308, USA
    Pediatrics 120:497-502. 2007
    ..The present experimental study was designed to determine how breastfeeding from a mother who smokes affects infants in the short-term...
  12. pmc Variety is the spice of life: strategies for promoting fruit and vegetable acceptance during infancy
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, United States
    Physiol Behav 94:29-38. 2008
    ....
  13. pmc Evaluation of the Monell forced-choice, paired-comparison tracking procedure for determining sweet taste preferences across the lifespan
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
    Chem Senses 36:345-55. 2011
    ..Although a single series will yield useful information about age-related differences in taste preferences, the 2-series version should be considered when differences in race/ethnicity are of interest...
  14. pmc The timing and duration of a sensitive period in human flavor learning: a randomized trial
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Am J Clin Nutr 93:1019-24. 2011
    ..By using the response to protein hydrolysate formula (PHF) as a model system, we discovered the existence of a sensitive period, before 4 mo, when exposure determines the hedonic tone to flavors...
  15. pmc Breast pumping and lactational state exert differential effects on ethanol pharmacokinetics
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Alcohol 44:141-8. 2010
    ....
  16. pmc Sleep disturbances after acute exposure to alcohol in mothers' milk
    J A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Alcohol 25:153-8. 2001
    ....
  17. pmc Prenatal and postnatal flavor learning by human infants
    J A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Pediatrics 107:E88. 2001
    ..The present study tested the hypothesis that experience with a flavor in amniotic fluid or breast milk modifies the infants' acceptance and enjoyment of similarly flavored foods at weaning...
  18. pmc Regulation of milk intake after exposure to alcohol in mothers' milk
    J A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104 3308, USA
    Alcohol Clin Exp Res 25:590-3. 2001
    ..Because breastfed infants are clearly capable of regulating milk intake, the present study tested the hypothesis that infants would compensate for the diminished milk intake if their mothers then refrained from drinking alcohol...
  19. pmc Differential growth patterns among healthy infants fed protein hydrolysate or cow-milk formulas
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Pediatrics 127:110-8. 2011
    ..In this randomized study, we examined whether healthy infants fed an extensively protein hydrolysate formula (PHF) would differ in feeding behavior and growth from those fed cow-milk formula (CMF)...
  20. pmc Optimizing oral medications for children
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104, USA
    Clin Ther 30:2120-32. 2008
    ..The unpalatable flavor of the medicine can thwart the benefits of even the most powerful of drugs. Failure to consume medication may do the child harm and can even be life-threatening...
  21. pmc Early milk feeding influences taste acceptance and liking during infancy
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA, USA
    Am J Clin Nutr 90:780S-788S. 2009
    ..We identified a model system that exploits the inherent taste variation in early feedings to investigate food preference development...
  22. pmc Breastfeeding and prolactin levels in lactating women with a family history of alcoholism
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Pediatrics 125:e1162-70. 2010
    ....
  23. pmc Acute alcohol consumption disrupts the hormonal milieu of lactating women
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, Pennsylvania 19104 3308, USA
    J Clin Endocrinol Metab 90:1979-85. 2005
    ..In the short term, mothers may be more relaxed, but the hormonal milieu underlying lactational performance is disrupted, and, in turn, the infant's milk supply is diminished...
  24. pmc Biphasic effects of moderate drinking on prolactin during lactation
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104 3308, USA
    Alcohol Clin Exp Res 32:1899-908. 2008
    ..Contrary to the popular lore that encourages women to drink alcohol as an aid to lactation, we previously showed that alcohol consumption disrupted lactational performance and the hormonal milieu of the lactating mother in the short term...
  25. pmc Short-term effects of alcohol consumption on the hormonal milieu and mood states in nulliparous women
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
    Alcohol 38:29-36. 2006
    ....
  26. ncbi Children's hedonic response to the smell of alcohol: effects of parental drinking habits
    J A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Alcohol Clin Exp Res 24:1167-71. 2000
    ..The present study focused on older children (3.8-6.0 years) to determine whether their hedonic response to the odor of alcohol was related to the drinking habits of their parents...
  27. pmc Flavor experiences during formula feeding are related to preferences during childhood
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Early Hum Dev 68:71-82. 2002
    ..These data are consistent with the hypothesis that flavor experiences influence subsequent flavor preferences even several years following the early experience...
  28. pmc Understanding the origin of flavor preferences
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Chem Senses 30:i242-3. 2005
  29. ncbi Feeding Infants and Toddlers Study: the types of foods fed to Hispanic infants and toddlers
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
    J Am Diet Assoc 106:S96-106. 2006
    ....
  30. pmc Flavor programming during infancy
    Julie A Mennella
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Pediatrics 113:840-5. 2004
    ..The present experimental study was motivated by clinical observations that early experience with formulas establishes subsequent preferences...
  31. pmc Vegetable acceptance by infants: effects of formula flavors
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Early Hum Dev 82:463-8. 2006
    ..01) when compared to those infants who were feeding milk-based formulas, a finding that further supports the hypothesis that mother-child dynamics surrounding early feeding impacts upon mothers' perception of their children's temperament...
  32. pmc Modification of bitter taste in children
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Dev Psychobiol 43:120-7. 2003
    ..However, based on sodium's differential ability to inhibit bitterness, as has been shown here with children and adults, clearly each drug of interest must be evaluated separately...
  33. pmc Children's hedonic judgments of cigarette smoke odor: effects of parental smoking and maternal mood
    Catherine A Forestell
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Psychol Addict Behav 19:423-32. 2005
    ..These findings suggest that some early learning about cigarette smoke odor is based on sensory experiences at home and anchors it to the emotional context in which their mothers smoke...
  34. pmc Psychophysical dissection of genotype effects on human bitter perception
    Julie A Mennella
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Chem Senses 36:161-7. 2011
    ..Human PROP sensitivity is determined by the combination of each of these 3 polymorphisms within the TAS2R38 gene...
  35. pmc Flavor perception in human infants: development and functional significance
    Gary K Beauchamp
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Digestion 83:1-6. 2011
    ..The flavor of a food determines its acceptability and modulates intake. It is thus critical to understand the factors that influence flavor preferences in humans...
  36. pmc Heightened sour preferences during childhood
    Djin Gie Liem
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Chem Senses 28:173-80. 2003
    ..Further research is needed to unfold the relationship between the level of sour taste preferred and the actual consumption of sour-tasting foods and flavors in children...
  37. pmc Obese women have lower monosodium glutamate taste sensitivity and prefer higher concentrations than do normal-weight women
    M Yanina Pepino
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Obesity (Silver Spring) 18:959-65. 2010
    ..Taken together, these data suggest that body weight is related to some components of umami taste and that different mechanisms are involved in the perception of threshold and suprathreshold MSG concentrations...
  38. pmc Advice given to women in Argentina about breast-feeding and the use of alcohol
    M Yanina Pepino
    Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104 3308, USA
    Rev Panam Salud Publica 16:408-14. 2004
    ..To explore the types of advice that women in Argentina received from health professionals, family members, and friends about drinking alcoholic beverages and about alcohol usage during pregnancy and lactation...
  39. doi Early flavor learning and its impact on later feeding behavior
    Gary K Beauchamp
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    J Pediatr Gastroenterol Nutr 48:S25-30. 2009
    ....
  40. pmc Lactational state modifies alcohol pharmacokinetics in women
    Marta Yanina Pepino
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Alcohol Clin Exp Res 31:909-18. 2007
    ..Given the physiological adaptations of the digestive system during lactation, the present study tested the hypothesis that lactation alters alcohol pharmacokinetics...
  41. pmc Factors contributing to individual differences in sucrose preference
    M Yanina Pepino
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Chem Senses 30:i319-20. 2005
  42. pmc Sucrose-induced analgesia is related to sweet preferences in children but not adults
    M Yanina Pepino
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104 3308, USA
    Pain 119:210-8. 2005
    ..The role that dietary habits and individual differences contribute to the preferences for sweet taste and its physiological consequences in children is an important area for future research...
  43. pmc Avoidance of hydrolyzed casein by mice
    Kristin L Field
    Monell Chemical Senses Center, Philadelphia, PA, 19104, USA
    Physiol Behav 93:189-99. 2008
    ..Our study suggests that mice may be a useful model for understanding the mechanisms of HC rejection...
  44. pmc Effects of cigarette smoking and family history of alcoholism on sweet taste perception and food cravings in women
    Marta Yanina Pepino
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Alcohol Clin Exp Res 31:1891-9. 2007
    ....
  45. pmc Early determinants of fruit and vegetable acceptance
    Catherine A Forestell
    Monell Chemical Senses Center, 3500 Market St, Philadelphia, PA 19104 3308, USA
    Pediatrics 120:1247-54. 2007
    ..Our goal was to evaluate the effects of breastfeeding and dietary experiences on acceptance of a fruit and a green vegetable by 4- to 8-month-old infants...
  46. pmc Similarities in food cravings and mood states between obese women and women who smoke tobacco
    M Yanina Pepino
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA
    Obesity (Silver Spring) 17:1158-63. 2009
    ....
  47. pmc Protein hydrolysates are avoided by herbivores but not by omnivores in two-choice preference tests
    Kristin L Field
    Monell Chemical Senses Center, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 4:e4126. 2009
    ..Recent, but taxonomically limited, evidence suggests that other animals also avoid consuming HC when alternatives exist...
  48. pmc Evaluating the prevalence of olfactory dysfunction in a pediatric population
    Pamela Dalton
    Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104, USA
    Ann N Y Acad Sci 1170:537-42. 2009
    ..The challenges confronted in studying this clinical population as well as extrapolation to larger populations will be discussed...
  49. ncbi Effects of breastfeeding chemosignals on the human menstrual cycle
    Suma Jacob
    The Institute for Mind and Biology, The University of Chicago, Chicago, IL 60637, USA
    Hum Reprod 19:422-9. 2004
    ..To date, there has not been an investigation to determine whether lactating women and their infants influence the ovarian function of other women with whom they interact...
  50. ncbi Social chemosignals from breastfeeding women increase sexual motivation
    Natasha A Spencer
    The Institute for Mind and Biology, The University of Chicago, Chicago, IL 60637, USA
    Horm Behav 46:362-70. 2004
    ....
  51. pmc The International society for developmental psychobiology 39th annual meeting symposium: Alcohol and development: beyond fetal alcohol syndrome
    Juan Carlos Molina
    Department of Psychology, Binghamton University, PO Box 6000, Binghamton, NY 13902 6000, USA
    Dev Psychobiol 49:227-42. 2007
    ..The studies under discussion indicate that, within each stage in development, we can trace alcohol-related experiences capable of determining or modulating alcohol seeking and intake patterns...

Research Grants21

  1. ALCOHOL EFFECT ON HUMAN LACTATION AND INFANT BEHAVIOR
    JULIE MENNELLA; Fiscal Year: 2007
    ..AIM 3: To explore the role of early experiences with ethanol in mothers' milk and the emotional context of such experiences, on the recognition of, and preference for, the sensory properties of ethanol ..
  2. MODEL FOR SENSITIVE PERIODS IN EARLY FLAVOR LEARNING
    JULIE MENNELLA; Fiscal Year: 2007
    ....
  3. MODEL FOR SENSITIVE PERIODS IN EARLY FLAVOR LEARNING
    JULIE MENNELLA; Fiscal Year: 2003
    ....
  4. ALCOHOL EFFECT ON HUMAN LACTATION AND INFANT BEHAVIOR
    JULIE MENNELLA; Fiscal Year: 2001
    ..These studies will have important ramifications for our understanding of issues relating to women's health during lactation and the effects of early experience with alcohol on infant nutrition, development and later preferences. ..
  5. MODEL FOR SENSITIVE PERIODS IN EARLY FLAVOR LEARNING
    Julie A Mennella; Fiscal Year: 2010
    ..abstract_text> ..