Detail Information
Publications
High level expression of proteins using sequences from the ferritin heavy chain gene locusHolly L Prentice
Momenta Pharmaceuticals, Inc, Cambridge, MA 02142, United States
J Biotechnol 128:50-60. 2007..The ferritin HC vector was able to generate cell lines with significantly higher expression levels than those under the control of the viral promoters...
Improving performance of mammalian cells in fed-batch processes through "bioreactor evolution"Holly L Prentice
Biogen Idec, Inc, 14 Cambridge Center, Cambridge, Massachusetts 02142, USA
Biotechnol Prog 23:458-64. 2007..These increases were obtained without any appreciable impact on product quality, demonstrating the usefulness of this simple approach to improve the performance of recombinant cell lines...
