R E Davis

Summary

Affiliation: MitoKor Inc
Country: USA

Publications

  1. pmc Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease
    R E Davis
    MitoKor, 11494 Sorrento Valley Road, San Diego, CA 92121, USA
    Proc Natl Acad Sci U S A 94:4526-31. 1997
  2. ncbi request reprint A novel mitochondrial DNA-like sequence in the human nuclear genome
    C Herrnstadt
    MitoKor, San Diego, California, 92121, USA
    Genomics 60:67-77. 1999
  3. ncbi request reprint Use of cytoplasmic hybrid cell lines for elucidating the role of mitochondrial dysfunction in Alzheimer's disease and Parkinson's disease
    S S Ghosh
    MitoKor, San Diego, California 92121, USA
    Ann N Y Acad Sci 893:176-91. 1999

Detail Information

Publications3

  1. pmc Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease
    R E Davis
    MitoKor, 11494 Sorrento Valley Road, San Diego, CA 92121, USA
    Proc Natl Acad Sci U S A 94:4526-31. 1997
    ..We suggest that specific point mutations in the CO1 and CO2 genes cause the CO defect in AD. A CO defect may represent a primary etiologic event, directly participating in a cascade of events that results in AD...
  2. ncbi request reprint A novel mitochondrial DNA-like sequence in the human nuclear genome
    C Herrnstadt
    MitoKor, San Diego, California, 92121, USA
    Genomics 60:67-77. 1999
    ....
  3. ncbi request reprint Use of cytoplasmic hybrid cell lines for elucidating the role of mitochondrial dysfunction in Alzheimer's disease and Parkinson's disease
    S S Ghosh
    MitoKor, San Diego, California 92121, USA
    Ann N Y Acad Sci 893:176-91. 1999
    ..These data suggest that the transfer of a mtDNA defect from disease donor platelets is the likely cause of the cybrid biochemical phenotype, and highlight the potential value of these cell lines as cellular disease models...