Patricia A Connolly

Summary

Affiliation: MiraVista Diagnostics
Country: USA

Publications

  1. pmc Detection of histoplasma antigen by a quantitative enzyme immunoassay
    Patricia A Connolly
    MiraVista Diagnostics, 4444 Decatur Blvd, Indianapolis, IN 46241, USA
    Clin Vaccine Immunol 14:1587-91. 2007
  2. pmc Blastomyces dermatitidis antigen detection by quantitative enzyme immunoassay
    Patricia Connolly
    MiraVista Diagnostics, Indianapolis, Indiana, USA
    Clin Vaccine Immunol 19:53-6. 2012
  3. doi request reprint Development of a Highly Sensitive and Specific Blastomycosis Antibody Enzyme Immunoassay Using Blastomyces dermatitidis Surface Protein BAD-1
    Sarah M Richer
    MiraVista Diagnostics, Indianapolis, Indiana, USA
    Clin Vaccine Immunol 21:143-6. 2014
  4. pmc Detection of Histoplasma capsulatum antigenuria by ultrafiltration of samples with false-negative results
    Lindsey Egan
    MiraVista Diagnostics, 4444 Decatur Blvd, Suite 300, Indianapolis, IN 46241, USA
    Clin Vaccine Immunol 15:726-8. 2008
  5. doi request reprint A multicenter evaluation of tests for diagnosis of histoplasmosis
    Chadi A Hage
    Pulmonary Critical Care Medicine, Richard L Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202, USA
    Clin Infect Dis 53:448-54. 2011
  6. pmc Pathogenic differences between North American and Latin American strains of Histoplasma capsulatum var. capsulatum in experimentally infected mice
    Michelle M Durkin
    MiraVista Diagnostics MiraBella Technologies, 4444 Decatur Blvd, Suite 300, Indianapolis, IN 46241, USA
    J Clin Microbiol 42:4370-3. 2004
  7. ncbi request reprint Antifungal therapy for central nervous system histoplasmosis, using a newly developed intracranial model of infection
    Ross R Haynes
    Histoplasmosis Reference Laboratory, Department of Medicine, Indiana University School of Medicine, 1001 W 10th Street, OPW 430, Indianapolis, IN 46202 2879, USA
    J Infect Dis 185:1830-2. 2002
  8. ncbi request reprint Urine polymerase chain reaction is not as sensitive as urine antigen for the diagnosis of disseminated histoplasmosis
    Yi Wei Tang
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Diagn Microbiol Infect Dis 54:283-7. 2006
  9. pmc Production of extracellular proteolytic activity by Histoplasma capsulatum grown in Histoplasma-macrophage medium is limited to restriction fragment length polymorphism class 1 isolates
    Robert Zarnowski
    Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, WI 53706, USA
    Diagn Microbiol Infect Dis 59:39-47. 2007

Collaborators

Detail Information

Publications9

  1. pmc Detection of histoplasma antigen by a quantitative enzyme immunoassay
    Patricia A Connolly
    MiraVista Diagnostics, 4444 Decatur Blvd, Indianapolis, IN 46241, USA
    Clin Vaccine Immunol 14:1587-91. 2007
    ..Sensitivity, specificity, and interassay precision are excellent in the new third-generation quantitative Histoplasma antigen immunoassay...
  2. pmc Blastomyces dermatitidis antigen detection by quantitative enzyme immunoassay
    Patricia Connolly
    MiraVista Diagnostics, Indianapolis, Indiana, USA
    Clin Vaccine Immunol 19:53-6. 2012
    ..Pretreatment increased the sensitivity for detection of antigenemia. Differentiation of histoplasmosis and blastomycosis is not possible by antigen detection...
  3. doi request reprint Development of a Highly Sensitive and Specific Blastomycosis Antibody Enzyme Immunoassay Using Blastomyces dermatitidis Surface Protein BAD-1
    Sarah M Richer
    MiraVista Diagnostics, Indianapolis, Indiana, USA
    Clin Vaccine Immunol 21:143-6. 2014
    ..This assay has the potential to aid in the diagnosis of blastomycosis. ..
  4. pmc Detection of Histoplasma capsulatum antigenuria by ultrafiltration of samples with false-negative results
    Lindsey Egan
    MiraVista Diagnostics, 4444 Decatur Blvd, Suite 300, Indianapolis, IN 46241, USA
    Clin Vaccine Immunol 15:726-8. 2008
    ..Antigen was detected following ultrafiltration in 73.8% of falsely negative specimens versus 2% of controls. Ultrafiltration improved sensitivity with a small reduction in specificity...
  5. doi request reprint A multicenter evaluation of tests for diagnosis of histoplasmosis
    Chadi A Hage
    Pulmonary Critical Care Medicine, Richard L Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202, USA
    Clin Infect Dis 53:448-54. 2011
    ..The goal of this study was to determine the sensitivity of the current antigen assay in different categories of histoplasmosis...
  6. pmc Pathogenic differences between North American and Latin American strains of Histoplasma capsulatum var. capsulatum in experimentally infected mice
    Michelle M Durkin
    MiraVista Diagnostics MiraBella Technologies, 4444 Decatur Blvd, Suite 300, Indianapolis, IN 46241, USA
    J Clin Microbiol 42:4370-3. 2004
    ..Mortality was higher with Latin American strains, and lung pathology showed large necrotizing granuloma with prominent neutrophilic infiltration. Chronic disease was unique to the North American strain...
  7. ncbi request reprint Antifungal therapy for central nervous system histoplasmosis, using a newly developed intracranial model of infection
    Ross R Haynes
    Histoplasmosis Reference Laboratory, Department of Medicine, Indiana University School of Medicine, 1001 W 10th Street, OPW 430, Indianapolis, IN 46202 2879, USA
    J Infect Dis 185:1830-2. 2002
    ..The hypothesis that amphotericin B-fluconazole combination therapy would be superior to amphotericin B monotherapy for treatment of CNS histoplasmosis was not supported by this study...
  8. ncbi request reprint Urine polymerase chain reaction is not as sensitive as urine antigen for the diagnosis of disseminated histoplasmosis
    Yi Wei Tang
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Diagn Microbiol Infect Dis 54:283-7. 2006
    ..Thus, positive PCR results in urine specimens correlate with positive culture results, but not with antigenuria. The low sensitivity of this PCR assay in urine limits its use in the diagnosis of disseminated histoplasmosis...
  9. pmc Production of extracellular proteolytic activity by Histoplasma capsulatum grown in Histoplasma-macrophage medium is limited to restriction fragment length polymorphism class 1 isolates
    Robert Zarnowski
    Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, WI 53706, USA
    Diagn Microbiol Infect Dis 59:39-47. 2007
    ..Overall, the feature of extracellular proteolytic activity production enables a convenient and unequivocal identification of RFLP class 1 isolates and, thereby, can be used in H. capsulatum strain differentiation and typing...