Mark D Spritzer
Affiliation: Middlebury College
Spritzer M, Fox E, Larsen G, Batson C, Wagner B, Maher J. Testosterone influences spatial strategy preferences among adult male rats. Horm Behav. 2013;63:800-12 pubmed publisher
..For this experiment, all groups seemed to use a combination of place and cued-response strategies. Overall, the results indicate that the effects of testosterone on spatial strategy preference are dose dependent and task dependent. ..
Spritzer M, Curtis M, DeLoach J, Maher J, Shulman L. Sexual interactions with unfamiliar females reduce hippocampal neurogenesis among adult male rats. Neuroscience. 2016;318:143-56 pubmed publisher
..In combination, these results indicate that interactions with unfamiliar females reduce adult neurogenesis and the effect is stronger for sexual interactions than for social interactions. ..
Wagner B, Braddick V, Batson C, Cullen B, Miller L, Spritzer M. Effects of testosterone dose on spatial memory among castrated adult male rats. Psychoneuroendocrinology. 2018;89:120-130 pubmed publisher
..Testosterone replacement restored spatial memory among castrated male rats on both behavioral tasks, but there was a complex dose-response relationship; therefore, the therapeutic value of testosterone is likely sensitive to dose. ..
Spritzer M, Ibler E, Inglis W, Curtis M. Testosterone and social isolation influence adult neurogenesis in the dentate gyrus of male rats. Neuroscience. 2011;195:180-90 pubmed publisher
..This suggests that normal circulating levels of testosterone may buffer against the neurogenesis-impairing effects of isolation, whereas high doses of testosterone do not. ..
Spritzer M, Panning A, Engelman S, Prince W, Casler A, Georgakas J, et al
. Seasonal and sex differences in cell proliferation, neurogenesis, and cell death within the dentate gyrus of adult wild-caught meadow voles. Neuroscience. 2017;360:155-165 pubmed publisher
..Overall, these results suggest higher levels of neuronal turn-over during the non-breeding season relative to the breeding season, possibly due to seasonal changes in sex steroids. ..