James H O'Keefe

Summary

Affiliation: Mid America Heart Institute
Country: USA

Publications

  1. ncbi request reprint Atorvastatin reduces remnant lipoproteins and small, dense low-density lipoproteins regardless of the baseline lipid pattern
    James H O'Keefe
    Mid America Heart Institute, St Luke s Hospital, 4401 Wornall Road, Suite 2000, Kansas City, MO 64111
    Prev Cardiol 7:154-60. 2004
  2. pmc Testing the performance of the ENRICHD Social Support Instrument in cardiac patients
    Joseph Vaglio
    Mid America Heart Institute at St Lukes Hospital, Kansas City, MO, USA
    Health Qual Life Outcomes 2:24. 2004
  3. pmc Primary and secondary prevention of cardiovascular diseases: a practical evidence-based approach
    James H O'Keefe
    Mid America Heart Institute and University of Missouri Kansas City, Missouri, USA
    Mayo Clin Proc 84:741-57. 2009
  4. doi request reprint Achieving hunter-gatherer fitness in the 21(st) century: back to the future
    James H O'Keefe
    Mid America Heart Institute University of Missouri Kansas City, Kansas City, MO 64111, USA
    Am J Med 123:1082-6. 2010
  5. ncbi request reprint Cardiovascular disease resulting from a diet and lifestyle at odds with our Paleolithic genome: how to become a 21st-century hunter-gatherer
    James H O'Keefe
    Mid America Heart Institute, Cardiovascular Consultants, Kansas City, MO 64111, USA
    Mayo Clin Proc 79:101-8. 2004
  6. doi request reprint The gravity of JUPITER (Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin)
    James H O'Keefe
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, MO 64111, USA
    Postgrad Med 121:113-8. 2009
  7. doi request reprint Organic fitness: physical activity consistent with our hunter-gatherer heritage
    James H O'Keefe
    Mid America Heart Institute University of Missouri Kansas City, MO, USA
    Phys Sportsmed 38:11-8. 2010
  8. ncbi request reprint Dietary strategies for the prevention & treatment of metabolic syndrome
    James H O'Keefe
    Mid America Heart Institute University of Missouri Kansas City, USA
    Mo Med 107:406-9. 2010
  9. doi request reprint Exercise like a hunter-gatherer: a prescription for organic physical fitness
    James H O'Keefe
    Mid America Heart and Vascular Institute University of Missouri, Kansas City, MO 64108, USA
    Prog Cardiovasc Dis 53:471-9. 2011
  10. ncbi request reprint Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal
    James H O'Keefe
    Mid America Heart Institute, Cardiovascular Consultants, Kansas City, Missouri 64111, USA
    J Am Coll Cardiol 43:2142-6. 2004

Collaborators

Detail Information

Publications114 found, 100 shown here

  1. ncbi request reprint Atorvastatin reduces remnant lipoproteins and small, dense low-density lipoproteins regardless of the baseline lipid pattern
    James H O'Keefe
    Mid America Heart Institute, St Luke s Hospital, 4401 Wornall Road, Suite 2000, Kansas City, MO 64111
    Prev Cardiol 7:154-60. 2004
    ..Increased attention should be paid to absolute concentrations of LDL subfraction cholesterol, which may be a more sensitive indicator of coronary heart disease risk than total LDL or an LDL pattern...
  2. pmc Testing the performance of the ENRICHD Social Support Instrument in cardiac patients
    Joseph Vaglio
    Mid America Heart Institute at St Lukes Hospital, Kansas City, MO, USA
    Health Qual Life Outcomes 2:24. 2004
    ..Validity and reliability of the ESSI, however, has not been formally tested in patients undergoing percutaneous coronary intervention (PCI)...
  3. pmc Primary and secondary prevention of cardiovascular diseases: a practical evidence-based approach
    James H O'Keefe
    Mid America Heart Institute and University of Missouri Kansas City, Missouri, USA
    Mayo Clin Proc 84:741-57. 2009
    ..Specific CV risk factors and optimal therapies for primary and secondary prevention are discussed...
  4. doi request reprint Achieving hunter-gatherer fitness in the 21(st) century: back to the future
    James H O'Keefe
    Mid America Heart Institute University of Missouri Kansas City, Kansas City, MO 64111, USA
    Am J Med 123:1082-6. 2010
    ..Suggestions for exercise mode, duration, intensity, and frequency are outlined with a focus on realigning our daily physical activities with the archetype that is encoded within our genome...
  5. ncbi request reprint Cardiovascular disease resulting from a diet and lifestyle at odds with our Paleolithic genome: how to become a 21st-century hunter-gatherer
    James H O'Keefe
    Mid America Heart Institute, Cardiovascular Consultants, Kansas City, MO 64111, USA
    Mayo Clin Proc 79:101-8. 2004
    ..This review outlines the essence of our hunter-gatherer genetic legacy and suggests practical steps to re-align our modern milieu with our ancient genome in an effort to improve cardiovascular health...
  6. doi request reprint The gravity of JUPITER (Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin)
    James H O'Keefe
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, MO 64111, USA
    Postgrad Med 121:113-8. 2009
    ..Simvastatin, at the 80-mg daily dose, is more toxic to muscles and liver than other statins at their highest dose, and thus should be used with caution...
  7. doi request reprint Organic fitness: physical activity consistent with our hunter-gatherer heritage
    James H O'Keefe
    Mid America Heart Institute University of Missouri Kansas City, MO, USA
    Phys Sportsmed 38:11-8. 2010
    ..In a sedentary individual, this type of daily physical activity should help confer the robust vigorous health that enabled our ancestors to survive and thrive as hunter-gatherers in the wild...
  8. ncbi request reprint Dietary strategies for the prevention & treatment of metabolic syndrome
    James H O'Keefe
    Mid America Heart Institute University of Missouri Kansas City, USA
    Mo Med 107:406-9. 2010
    ....
  9. doi request reprint Exercise like a hunter-gatherer: a prescription for organic physical fitness
    James H O'Keefe
    Mid America Heart and Vascular Institute University of Missouri, Kansas City, MO 64108, USA
    Prog Cardiovasc Dis 53:471-9. 2011
    ..In a typical inactive person, this type of daily physical activity will optimize gene expression and help to confer the robust health that was enjoyed by hunter-gatherers in the wild...
  10. ncbi request reprint Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal
    James H O'Keefe
    Mid America Heart Institute, Cardiovascular Consultants, Kansas City, Missouri 64111, USA
    J Am Coll Cardiol 43:2142-6. 2004
    ..No major safety concerns have surfaced in studies that lowered LDL to this range of 50 to 70 mg/dl. The current guidelines setting the target LDL at 100 to 115 mg/dl may lead to substantial undertreatment in high-risk individuals...
  11. doi request reprint Dietary strategies for improving post-prandial glucose, lipids, inflammation, and cardiovascular health
    James H O'Keefe
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, Missouri, USA
    J Am Coll Cardiol 51:249-55. 2008
    ..This anti-inflammatory diet should be considered for the primary and secondary prevention of coronary artery disease and diabetes...
  12. ncbi request reprint The renin-angiotensin-aldosterone system as a target in coronary disease
    James H O'Keefe
    Cardiovascular Consultants, Mid America Heart Institute, Suite 2000, 4320 Wornall Road, Kansas City, MO 64111, USA
    Curr Atheroscler Rep 5:124-30. 2003
    ..Aldosterone receptor blockers appear to provide additive benefit when used in conjunction with either an ACE inhibitor or an angiotensin receptor blocker...
  13. ncbi request reprint Alcohol and cardiovascular health: the razor-sharp double-edged sword
    James H O'Keefe
    Mid America Heart Institute, University of Missouri, Kansas City, Missouri, USA
    J Am Coll Cardiol 50:1009-14. 2007
    ..Alcohol should not be universally prescribed for health enhancement to nondrinking individuals owing to the lack of randomized outcome data and the potential for problem drinking...
  14. ncbi request reprint Postprandial hyperglycemia/hyperlipidemia (postprandial dysmetabolism) is a cardiovascular risk factor
    James H O'Keefe
    University of Missouri Kansas City, Kansas City, Missouri, USA
    Am J Cardiol 100:899-904. 2007
    ..Diet, exercise, and various pharmacologic agents can improve postprandial dysmetabolism. Using these strategies may help improve the prognosis for patients with diabetes mellitus and/or coronary heart disease...
  15. ncbi request reprint Eplerenone improves prognosis in postmyocardial infarction diabetic patients with heart failure: results from EPHESUS
    J H O'Keefe
    University of Missouri Kansas City School of Medicine, Mid America Heart Institute, St Luke s Hospital, Kansas City, MO 64111, USA
    Diabetes Obes Metab 10:492-7. 2008
    ..We retrospectively evaluated the effect of eplerenone vs. placebo in a subset of 1483 diabetic patients with LVSD and signs of CHF following AMI...
  16. ncbi request reprint Effect of chronic right ventricular apical pacing on left ventricular function
    James H O'Keefe
    Mid America Heart Institute, Kansas City, Missouri 64111, USA
    Am J Cardiol 95:771-3. 2005
    ....
  17. doi request reprint Cardiometabolic abnormalities in current National Football League players
    Michael A Selden
    University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    Am J Cardiol 103:969-71. 2009
    ..004; 100% vs 32%, p <0.001, and 95% vs 36%, p <0.001 respectively). In conclusion, cardiometabolic syndrome and its individual components were noted in current NFL players, particularly linemen...
  18. doi request reprint Elevated alanine aminotransferase in current national football league players: correlation with cardiometabolic syndrome markers, obesity, and insulin resistance
    Michael A Selden
    University of Missouri Kansas City School of Medicine, Saint Luke s Hospital of Kansas City, and Mid America Heart Institute, Kansas City, MO, USA
    South Med J 102:1003-6. 2009
    ....
  19. ncbi request reprint Comparison of outcomes among moderate alcohol drinkers before acute myocardial infarction to effect of continued versus discontinuing alcohol intake after the infarct
    Maia D Carter
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, Missouri, USA
    Am J Cardiol 105:1651-4. 2010
    ..In conclusion, these data suggest that there are no adverse effects for moderate drinkers to continue consuming alcohol and that they may have better physical functioning compared to those who quit drinking after an AMI...
  20. ncbi request reprint Clinical utility of coronary calcium scoring after nonischemic myocardial perfusion imaging
    Randall C Thompson
    Cardiovascular Consultants PC, 4330 Wornall Road, Suite 2000, Kansas City, MO 64111, USA
    J Nucl Cardiol 12:392-400. 2005
    ..Coronary artery calcium (CAC) scoring is increasingly being used after myocardial perfusion imaging (MPI) to detect preclinical coronary artery disease (CAD). However, there are few data to support this approach...
  21. ncbi request reprint Coffee and tea: perks for health and longevity?
    Salman K Bhatti
    aSaint Luke s Mid America Heart Institute and University of Missouri Kansas City, Kansas City, Missouri bJohn Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans cDepartment of Preventive Medicine, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Curr Opin Clin Nutr Metab Care 16:688-97. 2013
    ..The purpose of this review is to assess the health effects of chronic tea and/or coffee consumption...
  22. ncbi request reprint Coronary calcium screening in asymptomatic patients as a guide to risk factor modification and stress myocardial perfusion imaging
    Kevin W Moser
    Cardiovascular Consultants, Mid America Heart Institute, Saint Luke s Hospital, Kansas City, MO 64111, USA
    J Nucl Cardiol 10:590-8. 2003
    ....
  23. ncbi request reprint Effects of omega-3 fatty acids on resting heart rate, heart rate recovery after exercise, and heart rate variability in men with healed myocardial infarctions and depressed ejection fractions
    James H O'Keefe
    Mid America Heart Institute, Saint Luke s Hospital, Kansas City, Missouri, USA
    Am J Cardiol 97:1127-30. 2006
    ..These changes are consistent with an increase in vagal activity and may in part explain the observed decrease in risk for sudden cardiac death seen with omega-3 fatty acid supplementation...
  24. doi request reprint Dobutamine-induced chest pain does not predict ischemic findings on myocardial perfusion imaging
    John H Lee
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, Missouri, USA
    J Nucl Cardiol 15:526-9. 2008
    ..The purpose of this study is to explore the correlation between dobutamine-induced chest pain and evidence of ischemia on myocardial perfusion imaging (MPI)...
  25. doi request reprint Comparison of cardiovascular and metabolic risk factors in professional baseball players versus professional football players
    John H Helzberg
    Saint Luke s Hospital of Kansas City, University of Missouri Kansas City School of Medicine, Missouri, USA
    Am J Cardiol 106:664-7. 2010
    ....
  26. ncbi request reprint The rationale and indications for angiotensin receptor blockers in heart failure
    Kevin A Bybee
    Mid America Heart Institute, Kansas City, MO 64111, USA
    Heart Fail Clin 2:81-8. 2006
  27. ncbi request reprint Coronary artery disease prognosis and C-reactive protein levels improve in proportion to percent lowering of low-density lipoprotein
    James H O'Keefe
    Mid America Heart Institute, Kansas City, Missouri, USA
    Am J Cardiol 98:135-9. 2006
    ..Therefore, intensive LDL cholesterol reduction to levels of 30 to 70 mg/dl should be pursued in subjects with or at high risk for coronary artery disease...
  28. pmc Relation between red blood cell omega-3 fatty acid index and bleeding during acute myocardial infarction
    Adam C Salisbury
    Saint Luke s Mid America Heart and Vascular Institute, Kansas City, Missouri, USA
    Am J Cardiol 109:13-8. 2012
    ....
  29. ncbi request reprint Cumulative clinical trial data on atorvastatin for reducing cardiovascular events: the clinical impact of atorvastatin
    Kevin A Bybee
    Saint Luke s Mid America Heart Institute and University of Missouri Kansas City, Kansas City, MO, USA
    Curr Med Res Opin 24:1217-29. 2008
    ....
  30. pmc Predictors of omega-3 index in patients with acute myocardial infarction
    Adam C Salisbury
    Department of Cardiovascular Diseases, Saint Luke s Mid America Heart and Vascular Institute, Kansas City, MO 64111, USA
    Mayo Clin Proc 86:626-32. 2011
    ....
  31. pmc Strategies for optimizing glycemic control and cardiovascular prognosis in patients with type 2 diabetes mellitus
    James H O'Keefe
    Mid America Heart and Vascular Institute and University of Missouri Kansas City, Kansas City, MO, USA
    Mayo Clin Proc 86:128-38. 2011
    ..We conducted a systematic review of English articles using MEDLINE and the Cochrane Controlled Trials Register (1970-2010) using the following search terms: cardiovascular disease, randomized trials, hypoglycemia, and insulin resistance...
  32. doi request reprint Review article: eplerenone: an underused medication?
    Mohammad Abuannadi
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, MO, USA
    J Cardiovasc Pharmacol Ther 15:318-25. 2010
    ..In conclusion, eplerenone is a medication that offers the cardiovascular therapeutic and prognostic benefits of aldosterone antagonism but with fewer side effects compared to spironolactone...
  33. doi request reprint Neutralizing the adverse prognosis of coronary artery calcium
    Salman K Bhatti
    Saint Luke s Mid America Heart Institute, Kansas City Department of Internal Medicine, University of Missouri Kansas City School of Medicine, Kansas City
    Mayo Clin Proc 88:806-12. 2013
    ..To report and compare the outcomes and survival of patients with abnormal computed tomography-derived coronary artery calcium (CT-CAC) scores undergoing aggressive medical treatment at a cardiac prevention clinic...
  34. doi request reprint Regadenoson pharmacologic stress for myocardial perfusion imaging: a three-way comparison between regadenoson administered at peak exercise, during walk recovery, or no-exercise
    Randall C Thompson
    Saint Luke s Mid America Heart Institute, 4330 Wornall Road, Suite 2000, Kansas City, MO 64111, USA
    J Nucl Cardiol 20:214-21; quiz 222-6. 2013
    ..The aim of this study was to compare the clinical response of ExPeak-Reg, ExRec-Reg, and Rest-Reg...
  35. pmc Potential adverse cardiovascular effects from excessive endurance exercise
    James H O'Keefe
    Mid America Heart Institute of Saint Luke s Hospital of Kansas City, MO, USA
    Mayo Clin Proc 87:587-95. 2012
    ....
  36. doi request reprint Erectile dysfunction as a coronary artery disease risk equivalent
    John H Lee
    Mid America Heart Institute, Kansas City, MO, USA
    J Nucl Cardiol 15:800-3. 2008
    ....
  37. ncbi request reprint L-carnitine for the treatment of acute myocardial infarction
    James J Dinicolantonio
    Mid America Heart Institute at Saint Luke s Hospital, Kansas City, MO
    Rev Cardiovasc Med 15:52-62. 2014
    ..This article summarizes the evidence pertinent to the therapeutic use of L-carnitine for AMI...
  38. ncbi request reprint Omega-3 polyunsaturated fatty acids for the prevention of cardiovascular disease: do formulation, dosage & comparator matter?
    James J Dinicolantonio
    Mid America Heart Institute, Saint Luke s Hospital, Kansas City, USA
    Mo Med 110:495-8. 2013
    ....
  39. ncbi request reprint Meta-analysis of effect of dipeptidyl peptidase-4 inhibitors on cardiovascular risk in type 2 diabetes mellitus
    Harshal R Patil
    Saint Luke s Mid America Heart Institute, Kansas City, Missouri University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    Am J Cardiol 110:826-33. 2012
    ..40 (0.18 to 0.88, p = 0.02). In conclusion, this meta-analysis provides evidence that DPP4 inhibitors are safe from a CV standpoint and may possibly decrease risk of adverse CV events...
  40. doi request reprint Omega-3 fatty acids: cardiovascular benefits, sources and sustainability
    John H Lee
    Mid America Heart Institute and University of Missouri Kansas City, 64111, USA
    Nat Rev Cardiol 6:753-8. 2009
    ..Sustainable sources of omega-3 fatty acids will need to be identified if long-term cardiovascular risk reduction is to be achieved at the population level...
  41. doi request reprint Statins as antiarrhythmics: a systematic review part I: effects on risk of atrial fibrillation
    Hussam Abuissa
    University of Missouri, Kansas City, Missouri, USA
    Clin Cardiol 32:544-8. 2009
    ..Recent studies have demonstrated that statins may possess antiarrhythmic properties in addition to their lipid-lowering effects...
  42. doi request reprint Prevalence of vitamin D deficiency in patients with acute myocardial infarction
    John H Lee
    Mid America Heart and Vascular Institute and University of Missouri Kansas City, Kansas City, MO, USA
    Am J Cardiol 107:1636-8. 2011
    ..2 vs 29.0 kg/m(2), p = 0.025) were also observed in 25(OH)D-deficient subjects. In conclusion, vitamin D deficiency is present in almost all patients with acute myocardial infarction in a multicenter United States cohort...
  43. ncbi request reprint Vitamin D deficiency an important, common, and easily treatable cardiovascular risk factor?
    John H Lee
    Mid America Heart Institute and University of Missouri, Kansas City, Missouri, USA
    J Am Coll Cardiol 52:1949-56. 2008
    ..In the meanwhile, monitoring serum 25-hydroxyvitamin D levels and correction of vitamin D deficiency is indicated for optimization of musculoskeletal and general health...
  44. ncbi request reprint Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: a meta-analysis of randomized clinical trials
    Hussam Abuissa
    Mid America Heart Institute, Cardiovascular Consultants, Kansas City, Missouri 64111, USA
    J Am Coll Cardiol 46:821-6. 2005
    ..We sought to investigate the role of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) in preventing the new onset of type 2 diabetes mellitus...
  45. doi request reprint Diagnostic and clinical benefit of combined coronary calcium and perfusion assessment in patients undergoing PET/CT myocardial perfusion stress imaging
    Kevin A Bybee
    University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    J Nucl Cardiol 17:188-96. 2010
    ..One advantage of MPI with a hybrid CT device is the ability to obtain same-setting measurement of the coronary artery calcium score (CACS)...
  46. doi request reprint Association of coronary artery calcification with hepatic steatosis in asymptomatic individuals
    Rajiv Chhabra
    Department of Gastroenterology and Hepatology, Saint Luke s Hospital of Kansas City, Kansas City, MO Liver Disease Management Center and Division of Gastroenterology, Department of Medicine, Saint Luke s Hospital, Kansas City, MO School of Medicine, Department of Medicine, University of Missouri Kansas City, Kansas City, MO
    Mayo Clin Proc 88:1259-65. 2013
    ..To determine the association of coronary artery calcification with hepatic steatosis in asymptomatic volunteers...
  47. ncbi request reprint Autonomic tone as a cardiovascular risk factor: the dangers of chronic fight or flight
    Brian M Curtis
    Mid America Heart Institute of Saint Luke s Hospital and the University of Missouri, Kansas City, USA
    Mayo Clin Proc 77:45-54. 2002
    ..Other interventions, such as exercise, improve cardiovascular outcomes partially by increasing vagal activity and attenuating sympathetic hyperactivity...
  48. pmc Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis
    James B Wetmore
    Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS, USA
    BMC Res Notes 4:542. 2011
    ..abstract:..
  49. doi request reprint Omega-3 fatty acids for cardioprotection
    John H Lee
    Mid America Heart Institute and University of Missouri Kansas City, 4330 Wornall Road, Kansas City, MO 64111, USA
    Mayo Clin Proc 83:324-32. 2008
    ..Blood DHA and EPA levels could one day be used to identify patients with deficient levels and to individualize therapeutic recommendations...
  50. ncbi request reprint Interscan variability of coronary artery calcium quantification using an electrocardiographically pulsed spiral computed tomographic protocol
    Kevin W Moser
    Cardiovascular Imaging Technologies, L L C, Kansas City, Missouri, USA
    Am J Cardiol 93:1153-5. 2004
    ..For Agatston scores <10, the interscan variability of such a protocol was significantly lower than that for a sequential acquisition protocol. At higher Agatston scores, the 2 protocols had similar variability characteristics...
  51. doi request reprint Statins as anti-arrhythmics: a systematic review part II: effects on risk of ventricular arrhythmias
    Hussam Abuissa
    University of Missouri, Kansas City, Missouri, USA
    Clin Cardiol 32:549-52. 2009
    ..Recent studies have demonstrated that statins may possess anti-arrhythmic properties in addition to their lipid-lowering effects...
  52. doi request reprint Evidence-based diuretic therapy for improving cardiovascular prognosis in systemic hypertension
    Firas J Al Badarin
    Mid America Heart and Vascular Institute, Saint Luke s Hospital and University of Missouri Kansas City, Kansas City, Missouri, USA
    Am J Cardiol 107:1178-84. 2011
    ....
  53. ncbi request reprint Strategies to prevent type 2 diabetes
    Hussam Abuissa
    Mid America Heart Institute, Cardiovascular Consultants, Kansas City, MO 64111, USA
    Curr Med Res Opin 21:1107-14. 2005
    ....
  54. ncbi request reprint Optimal aspirin dose in acute coronary syndromes: an emerging consensus
    James J Dinicolantonio
    Saint Luke s Mid America Heart Institute, Kansas City, MO, USA
    Future Cardiol 10:291-300. 2014
    ..Despite this fact, current evidence suggests that aspirin doses of 75-100 mg/day may offer the optimal benefit:risk ratio in acute coronary syndrome patients...
  55. doi request reprint Meta-analysis comparing carvedilol versus metoprolol for the prevention of postoperative atrial fibrillation following coronary artery bypass grafting
    James J Dinicolantonio
    Department of Preventive Cardiology, Mid America Heart Institute at Saint Luke s Hospital, University of Missouri Kansas City, Kansas City, Missouri Electronic address
    Am J Cardiol 113:565-9. 2014
    ..50, 95% confidence interval 0.32 to 0.80). In conclusion, compared with metoprolol, carvedilol significantly reduces the incidence of postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting. ..
  56. ncbi request reprint Red yeast rice for dysipidemia
    Shariq Shamim
    Mid America Heart Institute, Saint Luke s Hospital, Kansas City, USA
    Mo Med 110:349-54. 2013
    ..However, many red yeast rice formulations are non-standardized and unregulated food supplements, and there is a need for further research and regulation of production...
  57. ncbi request reprint Psychosocial stress and cardiovascular disease: how to heal a broken heart
    James H O'Keefe
    Mid America Heart Institute, Cardiovascular Consultants, Kansas City, MO, USA
    Compr Ther 30:37-43. 2004
    ..Various factors, including depression, social isolation, hostility and anxiety increase cardiovascular risk, whereas social support, altruism, faith and optimism reduce risk...
  58. ncbi request reprint Behavioral cardiology: recognizing and addressing the profound impact of psychosocial stress on cardiovascular health
    Sajal Das
    Mid America Heart Institute, Kansas City, MO 64111, USA
    Curr Atheroscler Rep 8:111-8. 2006
    ..Simple screening questions are available to reliably indicate a patient at risk for psychosocial stress-related health problems...
  59. ncbi request reprint Clinical factors associated with left ventricular ejection fraction disparity in patients with left ventricular dysfunction undergoing multimodality imaging
    Adnan Khalid
    Saint Luke s Mid America Heart Institute, Kansas City, Missouri, USA
    Mo Med 109:489-92. 2012
    ..These clinical variables included atrial fibrillation, left ventricular hypertrophy, severe mitral regurgitation and paced rhythm...
  60. doi request reprint Review of cardiometabolic risk factors among current professional football and professional baseball players
    John H Helzberg
    Saint Luke s Hospital of Kansas City, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    Phys Sportsmed 38:77-83. 2010
    ..However, caution should be used in the interpretation of increased cardiovascular disease risk, as it does not necessarily translate into early increased mortality...
  61. ncbi request reprint Assessment of and physician response to glycemic control in diabetic patients presenting with an acute coronary syndrome
    Darcy L Green Conaway
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, MO 64111, USA
    Am Heart J 152:1022-7. 2006
    ..The frequency with which physicians assess diabetic patients' glycemic control during an ACS hospitalization is not known and may represent an opportunity for quality improvement...
  62. doi request reprint Cardiac physical diagnosis in the digital age: an important but increasingly neglected skill (from stethoscopes to microchips)
    Robert D Conn
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, Missouri, USA
    Am J Cardiol 104:590-5. 2009
    ..In conclusion, even in the digital age, the physical examination remains uniquely relevant to patient care, particularly when focused on the physiologic status of the cardiac patent...
  63. ncbi request reprint Cuppa joe: friend or foe? Effects of chronic coffee consumption on cardiovascular and brain health
    Harshal Patil
    Mid America Heart Institute, Saint Luke s Hospital, Kansas City, USA
    Mo Med 108:431-8. 2011
    ....
  64. doi request reprint A longer course of varenicline therapy improves smoking cessation rates
    John H Lee
    Mid America Heart Institute and University of Missouri Kansas City, USA
    Prev Cardiol 11:210-4. 2008
    ..In conclusion, a meta-analysis of randomized controlled trials suggests that longer duration of varenicline therapy improves long-term abstinence rates...
  65. doi request reprint Not all angiotensin-converting enzyme inhibitors are equal: focus on ramipril and perindopril
    James J Dinicolantonio
    Wegmans Pharmacy, Ithaca, NY, USA
    Postgrad Med 125:154-68. 2013
    ..Ramipril has an impressive track record of improving cardiovascular outcomes, too, and should be considered a preferred agent among the ACE inhibitor class. ..
  66. ncbi request reprint Frequency of undiagnosed diabetes mellitus in patients with acute coronary syndrome
    Darcy Green Conaway
    Mid America Heart Institute of Saint Luke s Hospital, University of Missouri, Kansas City, Missouri, USA
    Am J Cardiol 96:363-5. 2005
    ..A total of 57% of patients who had acute coronary syndrome had abnormal glucose metabolism; approximately 66% of those who met criteria for new diabetes were not diagnosed or treated as such by the physicians who managed them...
  67. ncbi request reprint Neckties for physicians: Yes? No? Maybe?
    Mohammad Abuannadi
    Mid America Heart Institute University of Missouri Kansas City, USA
    Mo Med 107:366-7. 2010
    ..Both pathogenic and non-pathogenic bacteria commonly colonize neckties and avoiding neckties is a simple measure that may prove helpful in our fight against nosocomial infections...
  68. ncbi request reprint Improving in-hospital mortality in the setting of an increasing risk profile among patients undergoing catheter-based reperfusion for an acute myocardial infarction without cardiogenic shock
    Steven P Marso
    Mid America Heart Institute, St Luke s Hospital, Kansas City, Missouri 64111, USA
    J Invasive Cardiol 15:711-6. 2003
    ..Therefore, we sought to identify significant predictors of in-hospital mortality, to determine the changing profile of patient demographics and to identify the mortality trend over time...
  69. ncbi request reprint Treatment of heart failure in patients with diabetes: clinical update
    David S H Bell
    Division of Endocrinology and Metabolism, The University of Alabama at Birmingham, School of Medicine, USA
    Ethn Dis 12:S1-12-8. 2002
    ..There is evidence that glycemic control is also important in improving clinical outcomes. The adverse effects of beta-blockade on carbohydrate and lipid metabolism and vasoconstriction may be circumvented by the use of carvedilol...
  70. ncbi request reprint Advantages of a third-generation beta-blocker in patients with diabetes mellitus
    David S H Bell
    Department of Medicine, University of Alabama at Birmingham Medical School, Birmingham, Alabama 35294, USA
    Am J Cardiol 93:49B-52B. 2004
    ..However, carvedilol, a nonselective beta-blocker with vasodilating and insulin-sensitizing properties, can largely circumvent these problems and is the ideal beta-blocker for the patient with diabetes...
  71. ncbi request reprint The effect of carvedilol on mortality risk in heart failure patients with diabetes: results of a meta-analysis
    David S H Bell
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Alabama Medical School, Birmingham, Alabama 35294, USA
    Curr Med Res Opin 22:287-96. 2006
    ..However, some trial results indicate that carvedilol, which blocks beta1-, beta2-, and alpha1-receptors and is a potent antioxidant, may produce at least comparable effects in both patient groups...
  72. ncbi request reprint Lipoprotein effects of different thiazolidinediones in clinical practice
    Fernando Ovalle
    Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham School of, Medicine, Birmingham, Alabama, USA
    Endocr Pract 8:406-10. 2002
    ..To investigate and compare the effects of troglitazone and rosiglitazone on plasma lipoproteins in patients with type 2 diabetes mellitus and dyslipidemia...
  73. ncbi request reprint Lowering blood pressure with beta-blockers in combination with other renin-angiotensin system blockers in patients with hypertension and type 2 diabetes: results from the GEMINI Trial
    Jackson T Wright
    Department of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
    J Clin Hypertens (Greenwich) 9:842-9. 2007
    ..The use of carvedilol compared with metoprolol did not effect glycemic control...
  74. ncbi request reprint Differential effects of beta-blockers on albuminuria in patients with type 2 diabetes
    George L Bakris
    Rush University Medical Center, Chicago, IL 60612, USA
    Hypertension 46:1309-15. 2005
    ..These differences cannot be explained by effects on blood pressure or alpha1-antagonism but may relate to antioxidant properties of carvedilol...
  75. pmc Advances in diabetes for the millennium: the heart and diabetes
    David S H Bell
    University of Alabama School of Medicine, Birmingham, USA
    MedGenMed 6:7. 2004
    ..Antidiabetic agents that target insulin resistance may be more cardioprotective than those that primarily augment insulin secretion...
  76. ncbi request reprint Optimizing treatment of diabetes and cardiovascular disease with combined alpha,beta-blockade
    David S H Bell
    Division of Endocrinology, Department of Medicine, University of Alabama Medical School, Birmingham, AL 35294, USA
    Curr Med Res Opin 21:1191-200. 2005
    ..Despite this benefit of beta-blockers, physicians have been reluctant to use them in patients with diabetes, in whom they are even more effective, because of the negative effects on carbohydrate and lipid metabolism...
  77. ncbi request reprint Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial
    George L Bakris
    Department of Preventive Medicine, Rush University Medical Center, Chicago, Ill, USA
    JAMA 292:2227-36. 2004
    ..Beta-blockers have been shown to decrease cardiovascular risk in patients with hypertension and type 2 diabetes mellitus (DM); however, some components of the metabolic syndrome are worsened by some beta-blockers...
  78. ncbi request reprint Statin neuropathy masquerading as diabetic autoimmune polyneuropathy
    Tom Brooks Vaughan
    Diabetes Care 28:2082. 2005
  79. ncbi request reprint Heart failure in the diabetic patient
    David S H Bell
    University of Alabama Medical School, Birmingham, AL, USA
    Cardiol Clin 25:523-38; vi. 2007
    ..Also reviewed are the therapies that are available for the treatment of diabetic HF and whether intensifying the use of these therapies might improve the worsened clinical outcomes for the patient who has diabetes...
  80. ncbi request reprint A comparison of agents used to manage type 2 diabetes mellitus: need for reappraisal of traditional approaches
    David S H Bell
    School of Medicine, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    Treat Endocrinol 3:67-76. 2004
    ..Furthermore, early use of an insulin-sensitizing agent either alone or incombination is expected to improve both acute and long-term outcomes in patients with type 2 diabetes...
  81. ncbi request reprint Postprandial dysmetabolism: the missing link between diabetes and cardiovascular events?
    David S H Bell
    Southside Endocrinology, Birmingham, Alabama 35205, USA
    Endocr Pract 14:112-24. 2008
    ..To investigate the association of postprandial dysmetabolism, ie, hyperglycemia, and hyperlipidemia with myocardial disease in diabetic, glucose-intolerant, and glucose-tolerant patients...
  82. ncbi request reprint Why I initiate therapy with two insulin sensitizers in patients with type 2 diabetes
    David S H Bell
    Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA
    Endocr Pract 9:98-101. 2003
  83. pmc Do sulfonylurea drugs increase the risk of cardiac events?
    David S H Bell
    University of Alabama at Birmingham, Birmingham, Ala, USA
    CMAJ 174:185-6. 2006
  84. ncbi request reprint Practical considerations and guidelines for dosing sulfonylureas as monotherapy or combination therapy
    David S H Bell
    University of Alabama Medical School, Faculty Office Towers, 510 20th Street South, Room 702, Birmingham, AL 35294, USA
    Clin Ther 26:1714-27. 2004
    ....
  85. ncbi request reprint Stockpiling of ovarian follicles and the response to rosiglitazone
    Tom Brooks Vaughan
    Diabetes Care 28:2333-4. 2005
  86. ncbi request reprint Heart failure: the frequent, forgotten, and often fatal complication of diabetes
    David S H Bell
    Department of Medicine, University of Alabama at Birmingham, USA
    Diabetes Care 26:2433-41. 2003
    ..Prophylactic utilization of ACE inhibitors and beta-blockers to avoid, rather than await, the need to treat HF should be considered in high-risk diabetic patients...
  87. ncbi request reprint Constructing an algorithm for managing type 2 diabetes. Focus on role of the thiazolidinediones
    Kathleen L Wyne
    Division of Endocrinology and Metabolism, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 8857, USA
    Postgrad Med . 2003
    ..Notably, decreasing insulin resistance also may reduce the incidence of adverse atherosclerotic consequences...
  88. ncbi request reprint Beneficial effects resulting from thiazolidinediones for treatment of type 2 diabetes mellitus
    David S H Bell
    University of Alabama at Birmingham, School of Medicine, Department of Medicine, Birmingham, USA
    Postgrad Med . 2003
    ..TZDs can be used safely in renally impaired patients with diabetes, and hepatotoxicity has not been a problem with second-generation TZDs, making these agents both safe and effective in the treatment of type 2 diabetes...
  89. ncbi request reprint Current status of diabetes treatment
    David S H Bell
    Department of Medicine, University of Alabama at Birmingham, 35294, USA
    South Med J 95:24-9. 2002
  90. ncbi request reprint Hyperinsulinemic hypoglycemia precipitated by weight loss
    Maria S Prelipcean
    University of Alabama Medical School, Birmingham, AL, USA
    South Med J 98:726-8. 2005
    ..To describe a case of hyperinsulinemic hypoglycemia precipitated by weight loss...
  91. ncbi request reprint Long-term efficacy of triple oral therapy for type 2 diabetes mellitus
    David S H Bell
    Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA
    Endocr Pract 8:271-5. 2002
    ..To report the status of 35 patients with type 2 diabetes mellitus approximately 3 years after the initiation of triple oral antidiabetic therapy--with a sulfonylurea, metformin, and a thiazolidinedione...
  92. ncbi request reprint A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia: response to Goldberg et al
    David S H Bell
    Diabetes Care 28:2983-4; author reply 2985-6. 2005
  93. ncbi request reprint Chronic complications of diabetes
    David S H Bell
    Department of Medicine, University of Alabama at Birmingham, 35294, USA
    South Med J 95:30-4. 2002
  94. ncbi request reprint The effectiveness of beta-blockers after myocardial infarction in patients with type 2 diabetes
    David S H Bell
    Diabetes Care 29:483; author reply 483-4. 2006
  95. doi request reprint Letter by Bell and O'keefe regarding article, "Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease"
    David S H Bell
    Circulation 118:e156; author reply e157. 2008
  96. ncbi request reprint Treatment of infertility in the polycystic ovary syndrome
    David S H Bell
    N Engl J Med 356:1999-2000; author reply 2000-1. 2007
  97. ncbi request reprint Insulin as initial therapy for type 2 diabetes is not in the patient's best interest
    David S H Bell
    University of Alabama School of Medicine, Birmingham, Alabama 35294, USA
    Endocr Pract 10:208-12. 2004
  98. ncbi request reprint Triple oral therapy for type 2 diabetes
    David S H Bell
    Diabetes Res Clin Pract 78:313-5. 2007
  99. ncbi request reprint Effect of rosiglitazone versus insulin on the pancreatic beta-cell function of subjects with type 2 diabetes
    Fernando Ovalle
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, The University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    Diabetes Care 27:2585-9. 2004
    ..To confirm our previous observations, we designed and performed a prospective, randomized, and controlled study...
  100. ncbi request reprint Insulin resistance and thrombogenesis: recent insights and therapeutic implications
    Hisham A Baalbaki
    Heart Health Center PC, Florence, Alabama 35631, USA
    Endocr Pract 13:679-86. 2007
    ..To review the relationship between insulin resistance and thrombogenesis, especially in the context of obesity, diabetes, and cardiovascular disease, and to discuss therapeutic implications...
  101. ncbi request reprint Insulin therapy in diabetes mellitus: how can the currently available injectable insulins be most prudently and efficaciously utilised?
    David S H Bell
    University of Alabama at Birmingham Medical School, Birmingham, Alabama, USA
    Drugs 67:1813-27. 2007
    ..In addition, maximisation of glycaemic control will result in prevention, delay of onset or amelioration of both the microvascular and perhaps the macrovascular complications of diabetes...