Research Topics
| Paul S ChanSummaryAffiliation: Mid America Heart Institute Country: USA Publications
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Detail Information
Publications
Long-term outcomes in elderly survivors of in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
N Engl J Med 368:1019-26. 2013..We determined rates of long-term survival and readmission among survivors of in-hospital cardiac arrest and examined whether these outcomes differed according to demographic characteristics and neurologic status at discharge...
Hospital-wide code rates and mortality before and after implementation of a rapid response teamPaul S Chan
Division of Cardiology, Mid America Heart Institute and University of Missouri, Kansas City, MO 64111, USA
JAMA 300:2506-13. 2008..Because a primary action of rapid response teams is to transfer patients to the ICU, their ability to reduce hospital-wide code rates and mortality remains unknown...
Racial differences in survival after in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, Fifth Floor, 4401 Wornall Rd, Kansas City, MO 64111, USA
JAMA 302:1195-201. 2009..Racial differences in survival have not been previously studied after in-hospital cardiac arrest, an event for which access to care is not likely to influence treatment...
Hospital variation in time to defibrillation after in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, Kansas City, Missouri 64111, USA
Arch Intern Med 169:1265-73. 2009..Delays to defibrillation are associated with worse survival after in-hospital cardiac arrest, but the degree to which hospitals vary in defibrillation response times and hospital predictors of delays remain unknown...
Racial and gender trends in the use of implantable cardioverter-defibrillators among Medicare beneficiaries between 1997 and 2003Paul S Chan
Department of Cardiovascular Research, Mid America Heart Institute, University of Missouri Kansas City, Kansas City, MO 64111, USA
Congest Heart Fail 15:51-7. 2009..After adjustment with multivariable regression models, differences in utilization rates between whites and men widened compared with blacks and women between 1997 and 2003, a period when indications for ICD therapy have expanded...
Echocardiographic dyssynchrony and health status outcomes from cardiac resynchronization therapy: insights from the PROSPECT trialPaul S Chan
Mid America Heart Institute, Kansas City, Missouri 64111, USA
JACC Cardiovasc Imaging 3:451-60. 2010..This study sought to assess the prognostic utility of echocardiographic dyssynchrony for health status improvement after cardiac resynchronization therapy (CRT)...
Delayed time to defibrillation after in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
N Engl J Med 358:9-17. 2008..However, empirical data on the prevalence of delayed defibrillation in the United States and its effect on survival are limited...
Automated external defibrillators and survival after in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, 4401 Wornall Rd, Fifth Floor, Kansas City, MO 64111, USA
JAMA 304:2129-36. 2010..Automated external defibrillators (AEDs) improve survival from out-of-hospital cardiac arrests, but data on their effectiveness in hospitalized patients are limited...
Concordance of physician ratings with the appropriate use criteria for coronary revascularizationPaul S Chan
Saint Luke s Mid America Heart Institute, Kansas City, Missouri 64111, USA
J Am Coll Cardiol 57:1546-53. 2011..The objective of this study was to compare the consistency in appropriate use criteria (AUC) ratings among a broad range of practicing cardiologists and the AUC Technical Panel...
Cardiac performance measure compliance in outpatients: the American College of Cardiology and National Cardiovascular Data Registry's PINNACLE (Practice Innovation And Clinical Excellence) programPaul S Chan
Mid America Heart Institute, Kansas City, Missouri 64111, USA
J Am Coll Cardiol 56:8-14. 2010....
Appropriateness of percutaneous coronary interventionPaul S Chan
Saint Luke s Mid America Heart and Vascular Institute, 4401 Wornall Rd, Fifth Floor, Kansas City, MO 64111, USA
JAMA 306:53-61. 2011..Despite the widespread use of percutaneous coronary intervention (PCI), the appropriateness of these procedures in contemporary practice is unknown...
Rapid Response Teams: A Systematic Review and Meta-analysisPaul S Chan
Department of Internal Medicine, Mid America Heart Institute at St Luke s Hospital, University of Missouri Kansas City, MO 64111, USA
Arch Intern Med 170:18-26. 2010..We conducted a meta-analysis to assess the effect of RRTs on reducing cardiopulmonary arrest and hospital mortality rates...
Impact of age and medical comorbidity on the effectiveness of implantable cardioverter-defibrillators for primary preventionPaul S Chan
Mid America Heart Institute and University of Missouri, Kansas City, MO 64111, USA
Circ Cardiovasc Qual Outcomes 2:16-24. 2009....
A validated prediction tool for initial survivors of in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, Kansas City, Missouri 64111, USA
Arch Intern Med 172:947-53. 2012..Accurate estimation of favorable neurological survival after in-hospital cardiac arrest could provide critical information for physicians, patients, and families...
Diagnostic blood loss from phlebotomy and hospital-acquired anemia during acute myocardial infarctionAdam C Salisbury
Department of Internal Medicine, Division of Cardiovascular Disease, Saint Luke s Mid America Heart and Vascular Institute, Kansas City, MO 64111, USA
Arch Intern Med 171:1646-53. 2011..The extent to which diagnostic phlebotomy, a modifiable process of care, contributes to HAA is unknown...
Fragmented QRS and mortality risk in patients with left ventricular dysfunctionAamir Cheema
Mid America Heart Institute and the University of Missouri, Kansas City, MO, USA
Circ Arrhythm Electrophysiol 3:339-44. 2010..Whether fQRS improves patient selection for primary prevention patients eligible for implantable cardioverter-defibrillator (ICD) therapy remains unknown...
Red blood cell indices and development of hospital-acquired anemia during acute myocardial infarctionAdam C Salisbury
Saint Luke s Mid America Heart and Vascular Institute, Kansas City, Missouri, USA
Am J Cardiol 109:1104-10. 2012..34, 95% confidence interval 1.08 to 1.65) were independently more likely to develop moderate-severe HAA. In conclusion, increased RDW and low MCV were independent predictors of moderate-severe HAA...
Trends in survival after in-hospital cardiac arrestSaket Girotra
University of Iowa Hospitals and Clinics, Department of Internal Medicine, Division of Cardiovascular Diseases, 200 Hawkins Dr, Suite 4430 RCP, Iowa City, IA 52242, USA
N Engl J Med 367:1912-20. 2012..Despite advances in resuscitation care in recent years, it is not clear whether survival and neurologic function after in-hospital cardiac arrest have improved over time...
Hospital-acquired anemia and in-hospital mortality in patients with acute myocardial infarctionAdam C Salisbury
Saint Luke s Mid Asmerica Heart and Vascular Institute, Kansas City, MO 64111, USA
Am Heart J 162:300-309.e3. 2011..The relationship between HAA and adverse in-hospital outcomes may be particularly relevant to hospitals' efforts to implement prevention programs, but the association between HAA and in-hospital mortality is unclear...
Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status (TRIUMPH): design and rationale of a prospective multicenter registrySuzanne V Arnold
Saint Luke s Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, USA
Circ Cardiovasc Qual Outcomes 4:467-76. 2011....
Association of somatic and cognitive depressive symptoms and biomarkers in acute myocardial infarction: insights from the translational research investigating underlying disparities in acute myocardial infarction patients' health status registryKim G Smolderen
Saint Luke s Mid America Heart and Vascular Institute, 4401 Wornall Road, Kansas City, MO 64111, USA
Biol Psychiatry 71:22-9. 2012....
Patient health status and costs in heart failure: insights from the eplerenone post-acute myocardial infarction heart failure efficacy and survival study (EPHESUS)Paul S Chan
St Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
Circulation 119:398-407. 2009..We assessed whether health status assessment with the Kansas City Cardiomyopathy Questionnaire (KCCQ) predicts future costs in stable heart failure outpatients with left ventricular dysfunction after myocardial infarction...
Predictors of omega-3 index in patients with acute myocardial infarctionAdam C Salisbury
Department of Cardiovascular Diseases, Saint Luke s Mid America Heart and Vascular Institute, Kansas City, MO 64111, USA
Mayo Clin Proc 86:626-32. 2011....
Effectiveness of implantable cardioverter-defibrillators in patients with ischemic heart disease and left ventricular dysfunctionPaul S Chan
Division of Cardiology, University of Michigan, Ann Arbor, USA
Arch Intern Med 166:2228-33. 2006..To investigate the generalizabilty of this mortality reduction, we examined the effectiveness of ICDs in clinical practice...
Statin use in outpatients with obstructive coronary artery diseaseSuzanne V Arnold
MHA, St Luke s Mid America Heart Institute, 4401 Wornall Rd, Kansas City, MO 64111, USA
Circulation 124:2405-10. 2011..We sought to determine the extent to which patients with obstructive CAD in routine outpatient care are treated with statins, nonstatins, or no lipid-lowering therapy...
Carotid artery stenting of a contralateral occlusion and in-hospital outcomes: results from the CARE (Carotid Artery Revascularization and Endarterectomy) registryNestor Mercado
Saint Luke s Mid America Heart Institute, University of Missouri Kansas City, 4401 Wornall Road, Kansas City, MO 64111, USA
JACC Cardiovasc Interv 6:59-64. 2013..The authors sought to study the characteristics and outcomes of patients with contralateral carotid artery occlusions (CCOs) undergoing elective carotid artery stenting (CAS)...
Mortality reduction by implantable cardioverter-defibrillators in high-risk patients with heart failure, ischemic heart disease, and new-onset ventricular arrhythmia: an effectiveness studyPaul S Chan
Division of Cardiology, University of Michigan School of Medicine, USA
J Am Coll Cardiol 45:1474-81. 2005..To investigate the generalizability of the reduction in mortality posed by implantable cardioverter-defibrillators, we examined the effectiveness of defibrillators as applied in routine medical practice...
Do Beta-blockers impact microvolt T-wave alternans testing in patients at risk for ventricular arrhythmias? A meta-analysisPaul S Chan
Mid America Heart Institute, Kansas City, MO 64111, USA
J Cardiovasc Electrophysiol 21:1009-14. 2010....
Treatment differences by health insurance among outpatients with coronary artery disease: insights from the national cardiovascular data registryKim G Smolderen
Saint Luke s Mid America Heart Institute, Kansas City, Missouri 64111, USA
J Am Coll Cardiol 61:1069-75. 2013..This study examined the association between insurance status and physicians' adherence with providing evidence-based treatments for coronary artery disease (CAD)...
Survival benefit with drug-eluting stents in observational studies: fact or artifact?Lakshmi Venkitachalam
Saint Luke s Mid America Heart Institute, University of Missouri Kansas City School of Medicine, 4401 Wornall Road, Kansas City, MO 64111, USA
Circ Cardiovasc Qual Outcomes 4:587-94. 2011....
Prognostic implication of redefining indeterminate microvolt T-wave alternans studies as abnormal or normalPaul S Chan
Division of Cardiology, University of Michigan, Ann Arbor, MI, USA
Am Heart J 153:523-9. 2007..The objective of this study was to assess if patients have differences in survival prognosis based on the reasons for an indeterminate MTWA result...
Usefulness of microvolt T-wave alternans to predict outcomes in patients with ischemic cardiomyopathy beyond one yearPaul S Chan
Mid America Heart Institute and University of Missouri, Kansas City, Missouri, USA
Am J Cardiol 102:280-4. 2008..Although these findings need further validation, they suggest that rescreening with MTWA may not need to be performed more frequently than once every 2 years...
Practice-level variation in warfarin use among outpatients with atrial fibrillation (from the NCDR PINNACLE program)Paul S Chan
Mid America Heart Institute, Kansas City, Missouri, USA
Am J Cardiol 108:1136-40. 2011..Our findings suggest important opportunities for practice-level improvement in stroke prevention for outpatients with AF and define a benchmark treatment rate before the introduction of newer anticoagulant agents...
Economic impact of angina after an acute coronary syndrome: insights from the MERLIN-TIMI 36 trialSuzanne V Arnold
Saint Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
Circ Cardiovasc Qual Outcomes 2:344-53. 2009..Angina in patients with coronary artery disease is associated with worse quality of life; however, the relationship between angina frequency and resource utilization is unknown...
Cost-effectiveness of targeting patients undergoing percutaneous coronary intervention for therapy with bivalirudin versus heparin monotherapy according to predicted risk of bleedingAmit P Amin
Saint Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
Circ Cardiovasc Qual Outcomes 3:358-65. 2010....
Health literacy and outcomes among patients with heart failurePamela N Peterson
Division of Cardiology, Denver Health Medical Center, Mail Code 0960, 777 Bannock St, Denver, CO 80204, USA
JAMA 305:1695-701. 2011..Little is known about the effects of low health literacy among patients with heart failure, a condition that requires self-management and frequent interactions with the health care system...
Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysisJames B Wetmore
Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS, USA
BMC Res Notes 4:542. 2011..abstract:..
Patterns and predictors of fast food consumption after acute myocardial infarctionAdam C Salisbury
Saint Luke s Mid America Heart and Vascular Institute, Kansas City, Missouri, USA
Am J Cardiol 107:1105-10. 2011..Novel interventions that go beyond traditional dietary counseling may be needed to address continued fast food consumption after AMI in these patients...
Are changes in carotid intima-media thickness related to risk of nonfatal myocardial infarction? A critical review and meta-regression analysisZachary D Goldberger
Department of Internal Medicine, Division of Cardiology, University of Michigan Health System, Ann Arbor, MI, USA
Am Heart J 160:701-14. 2010..However, it remains unclear whether changes in CIMT that result from these therapies correlate with nonfatal myocardial infarction (MI)...
Cost-effectiveness of radiofrequency catheter ablation for atrial fibrillationPaul S Chan
Division of Cardiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
J Am Coll Cardiol 47:2513-20. 2006..We sought to compare the cost-effectiveness of left atrial catheter ablation (LACA), amiodarone, and rate control therapy in the management of atrial fibrillation (AF)...
Vasodilator therapy in patients with aortic insufficiency: a systematic reviewAli Mahajerin
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109 0366, USA
Am Heart J 153:454-61. 2007..The use of vasodilators to improve long-term outcomes in asymptomatic patients with chronic aortic insufficiency (AI) is controversial...
Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery diseasePaul S Chan
University of Michigan Department of Internal Medicine, Ann Arbor, MI, USA
Circulation 115:2398-409. 2007..However, the actual benefit and cost-effectiveness of high-dose statin therapy are unknown...
Microvolt T-wave alternans: where do we go from here?Paul S Chan
J Am Coll Cardiol 47:1736; author reply 1736-7. 2006
Prognostic utility of microvolt T-wave alternans in risk stratification of patients with ischemic cardiomyopathyTheodore Chow
The Lindner Clinical Trial Center at the Christ Hospital and the Ohio Heart and Vascular Center, Cincinnati, Ohio, USA
J Am Coll Cardiol 47:1820-7. 2006..08 [1.18 to 3.66]; p = 0.01). CONCLUSIONS: Microvolt T-wave alternans is a strong and independent predictor of all-cause and arrhythmic mortality in patients with ischemic cardiomyopathy...
