Chengfeng Yang

Summary

Affiliation: Michigan State University
Country: USA

Publications

  1. Zhao Y, Tan Y, Strynar M, Perez G, Haslam S, Yang C. Perfluorooctanoic acid effects on ovaries mediate its inhibition of peripubertal mammary gland development in Balb/c and C57Bl/6 mice. Reprod Toxicol. 2012;33:563-576 pubmed publisher
    ..These results indicate that PFOA effects on ovaries mediate its inhibition of mammary gland development in Balb/c and C57Bl/6 mice and that PPARĪ± expression is a contributing factor. ..
  2. Humphries B, Wang Z, Oom A, Fisher T, Tan D, Cui Y, et al. MicroRNA-200b targets protein kinase C? and suppresses triple-negative breast cancer metastasis. Carcinogenesis. 2014;35:2254-63 pubmed publisher
    ..Our findings suggest that miR-200b and PKC? may serve as promising therapeutic targets for metastatic TNBC. ..
  3. Li Z, Liu X, Wang L, Wang Y, DU C, Xu S, et al. The role of PGC-1? and MRP1 in lead-induced mitochondrial toxicity in testicular Sertoli cells. Toxicology. 2016;355-356:39-48 pubmed publisher
    ..Together, the findings from this study suggest that PGC-1? and MRP1 plays important roles in protecting TM4 cells against lead-induced mitochondrial toxicity, providing a better understanding of lead-induced mitochondrial toxicity. ..
  4. Wang Z, Humphries B, Xiao H, Jiang Y, Yang C. MicroRNA-200b suppresses arsenic-transformed cell migration by targeting protein kinase C? and Wnt5b-protein kinase C? positive feedback loop and inhibiting Rac1 activation. J Biol Chem. 2014;289:18373-86 pubmed publisher
    ..Together, these findings indicate that miR-200b suppresses arsenic-transformed cell migration by targeting PKC? and Wnt5b-PKC? positive feedback loop and subsequently inhibiting Rac1 activation. ..
  5. Humphries B, Wang Z, Yang C. The role of microRNAs in metal carcinogen-induced cell malignant transformation and tumorigenesis. Food Chem Toxicol. 2016;98:58-65 pubmed publisher
    ..This review aims to discuss recent studies showing that miRNAs play important roles in metal carcinogen-induced cell malignant transformation and tumorigenesis. Some thoughts for future further studies in this field are also presented. ..