Kurt Williams

Summary

Affiliation: Michigan State University
Country: USA

Publications

  1. doi request reprint Gammaherpesviruses and pulmonary fibrosis: evidence from humans, horses, and rodents
    K J Williams
    Department of Pathobiology and Diagnostic Investigation, G380 Veterinary Medical Center, College of Veterinary Medicine, 784 Wilson Rd, Michigan State University, East Lansing, MI 48824, USA Email
    Vet Pathol 51:372-84. 2014
  2. ncbi request reprint Pulmonary heat shock protein expression after exposure to a metabolically activated Clara cell toxicant: relationship to protein adduct formation
    Kurt J Williams
    Department of Veterinary Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Toxicol Appl Pharmacol 192:107-18. 2003
  3. ncbi request reprint Coronary arteriosclerosis with myocardial atrophy in a 13-year-old dog
    K J Williams
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, 210 Food Safety and Toxicology Building, Michigan State University, East Lansing, MI 48824, USA
    Vet Pathol 40:695-7. 2003
  4. ncbi request reprint Identification of spontaneous feline idiopathic pulmonary fibrosis: morphology and ultrastructural evidence for a type II pneumocyte defect
    Kurt Williams
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA
    Chest 125:2278-88. 2004
  5. doi request reprint Regional pulmonary veno-occlusion: a newly identified lesion of equine exercise-induced pulmonary hemorrhage
    K J Williams
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Pathol 45:316-26. 2008
  6. ncbi request reprint Equine multinodular pulmonary fibrosis: a newly recognized herpesvirus-associated fibrotic lung disease
    K J Williams
    College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Pathol 44:849-62. 2007
  7. ncbi request reprint Regional distribution of collagen and haemosiderin in the lungs of horses with exercise-induced pulmonary haemorrhage
    F J Derksen
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan 48824, USA
    Equine Vet J 41:586-91. 2009
  8. ncbi request reprint Pulmonary response to airway instillation of autologous blood in horses
    F J Derksen
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, Michigan 48824, USA
    Equine Vet J 39:334-9. 2007
  9. ncbi request reprint Exercise-induced pulmonary hemorrhage in horses: the role of pulmonary veins
    FREDERIK DERKSEN
    Michigan State University, USA
    Compend Contin Educ Vet 33:E6. 2011
  10. ncbi request reprint Histological evaluation of the equine larynx after unilateral laser-assisted ventriculocordectomy
    P Robinson
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, Michigan 48824, USA
    Equine Vet J 39:222-5. 2007

Collaborators

Detail Information

Publications23

  1. doi request reprint Gammaherpesviruses and pulmonary fibrosis: evidence from humans, horses, and rodents
    K J Williams
    Department of Pathobiology and Diagnostic Investigation, G380 Veterinary Medical Center, College of Veterinary Medicine, 784 Wilson Rd, Michigan State University, East Lansing, MI 48824, USA Email
    Vet Pathol 51:372-84. 2014
    ..The experimental data are considered in the context of the pathogenesis of naturally occurring pulmonary fibrosis in humans and horses. ..
  2. ncbi request reprint Pulmonary heat shock protein expression after exposure to a metabolically activated Clara cell toxicant: relationship to protein adduct formation
    Kurt J Williams
    Department of Veterinary Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Toxicol Appl Pharmacol 192:107-18. 2003
    ....
  3. ncbi request reprint Coronary arteriosclerosis with myocardial atrophy in a 13-year-old dog
    K J Williams
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, 210 Food Safety and Toxicology Building, Michigan State University, East Lansing, MI 48824, USA
    Vet Pathol 40:695-7. 2003
    ..These vascular lesions likely lead to insufficient perfusion of the affected myocardium and gradual loss of myofibers without the acute necrosis and fibrosis characteristic of infarction...
  4. ncbi request reprint Identification of spontaneous feline idiopathic pulmonary fibrosis: morphology and ultrastructural evidence for a type II pneumocyte defect
    Kurt Williams
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA
    Chest 125:2278-88. 2004
    ....
  5. doi request reprint Regional pulmonary veno-occlusion: a newly identified lesion of equine exercise-induced pulmonary hemorrhage
    K J Williams
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Pathol 45:316-26. 2008
    ....
  6. ncbi request reprint Equine multinodular pulmonary fibrosis: a newly recognized herpesvirus-associated fibrotic lung disease
    K J Williams
    College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Pathol 44:849-62. 2007
    ..Further, we propose that this newly described disease develops in association with infection by the equine gamma-herpesvirus, EHV-5...
  7. ncbi request reprint Regional distribution of collagen and haemosiderin in the lungs of horses with exercise-induced pulmonary haemorrhage
    F J Derksen
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan 48824, USA
    Equine Vet J 41:586-91. 2009
    ..The current study quantified site-specific changes in vein walls, collagen and haemosiderin accumulation, and pleural vascular profiles in the lungs of horses suffering EIPH...
  8. ncbi request reprint Pulmonary response to airway instillation of autologous blood in horses
    F J Derksen
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, Michigan 48824, USA
    Equine Vet J 39:334-9. 2007
    ..Associated pulmonary lesions include alveolar and airway wall fibrosis, which may enhance the severity of EIPH. Further work is required to understand the pulmonary response to blood in the equine airways...
  9. ncbi request reprint Exercise-induced pulmonary hemorrhage in horses: the role of pulmonary veins
    FREDERIK DERKSEN
    Michigan State University, USA
    Compend Contin Educ Vet 33:E6. 2011
    ..During exercise, venous occlusion increases regional pulmonary capillary pressure, likely causing capillary rupture and resulting in bleeding...
  10. ncbi request reprint Histological evaluation of the equine larynx after unilateral laser-assisted ventriculocordectomy
    P Robinson
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, Michigan 48824, USA
    Equine Vet J 39:222-5. 2007
    ..However, removal of the vocal fold and ventricle takes considerable laser energy and could cause collateral tissue damage, including injury to the adjacent laryngeal cartilages...
  11. doi request reprint Multinodular pulmonary fibrosis in five horses
    David M Wong
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Am Vet Med Assoc 232:898-905. 2008
    ..5 horses were evaluated because of decreased appetite, weight loss, fever, cough, tachypnea, and respiratory distress...
  12. pmc Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT
    Naoki Kiyosawa
    Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA
    BMC Genomics 9:487. 2008
    ....
  13. ncbi request reprint o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver
    Naoki Kiyosawa
    Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Toxicol Sci 101:350-63. 2008
    ..Based on the species-specific differences in CAR regulation, the extrapolation of rodent DDT hepatocarcinogenicity to humans warrants further investigation...
  14. ncbi request reprint Diarrhea and hyperammonemia in a horse with progressive neurologic signs
    Julia E Stickle
    Diagnostic Center for Population and Animal Health, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA
    Vet Clin Pathol 35:250-3. 2006
    ..Intestinal bacteria as a source of hyperammonemia in the absence of hepatic disease has been linked rarely to positive culture results for clostridial organisms...
  15. pmc Induction of tolerance to naphthalene in Clara cells is dependent on a stable phenotypic adaptation favoring maintenance of the glutathione pool
    Jay A A West
    Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, California, USA
    Am J Pathol 160:1115-27. 2002
    ....
  16. ncbi request reprint An experimental model of allergic asthma in cats sensitized to house dust mite or bermuda grass allergen
    Carol R Norris Reinero
    Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, California, USA
    Int Arch Allergy Immunol 135:117-31. 2004
    ....
  17. pmc Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice
    Cora J Fong
    Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA
    BMC Genomics 8:151. 2007
    ..These results were systematically compared to the effects elicited by the potent estrogen receptor ligand 17alpha-ethynylestradiol (EE) to identify pathways similarly and uniquely modified by each compound...
  18. ncbi request reprint Consequences of abrupt glutathione depletion in murine Clara cells: ultrastructural and biochemical investigations into the role of glutathione loss in naphthalene cytotoxicity
    Andrew J Phimister
    Department of Molecular Biosciences, University of California, Davis, CA 95616, USA
    J Pharmacol Exp Ther 314:506-13. 2005
    ..This suggests that glutathione depletion may be responsible for some aspects of naphthalene cytotoxicity, but it is not sufficient to cause cell death without further stresses...
  19. ncbi request reprint Identification and characterization of an idiopathic pulmonary fibrosis-like condition in cats
    Leah A Cohn
    Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO 65211, USA
    J Vet Intern Med 18:632-41. 2004
    ..Cats with histologic changes compatible with UIP had signs that mimicked many of the clinical findings of human IPF, and treatment response was similarly unrewarding...
  20. ncbi request reprint Inhibition of estrogen-mediated uterine gene expression responses by dioxin
    Darrell R Boverhof
    Michigan State University, Department of Biochemistry and Molecular Biology, 224 Biochemistry Building, Wilson Road, East Lansing, MI 48824 1319, USA
    Mol Pharmacol 73:82-93. 2008
    ..These inhibited responses correlate with the observed histological alterations and may contribute to the antiuterotrophic effects of TCDD...
  21. ncbi request reprint Imaging diagnosis--Feline idiopathic pulmonary fibrosis
    Scott A Secrest
    Cheat Lake Animal Hospital, Morgantown, WV, USA
    Vet Radiol Ultrasound 49:47-50. 2008
  22. ncbi request reprint Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/8/34 in the absence and presence of Delta9-tetrahydrocannabinol
    John P Buchweitz
    Department of Pharmacology and Toxicology, and Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824 1317, USA
    J Leukoc Biol 83:785-96. 2008
    ..Collectively, the immune and airway epithelial cell responses to PR8 challenge in Delta(9)-THC-treated CB(1)-/-/CB(2)-/- and wild-type mice indicated the involvement of CB(1)/CB(2) receptor-dependent and -independent mechanisms...
  23. ncbi request reprint Modulation of airway responses to influenza A/PR/8/34 by Delta9-tetrahydrocannabinol in C57BL/6 mice
    John P Buchweitz
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan 48824 1317, USA
    J Pharmacol Exp Ther 323:675-83. 2007
    ..Collectively, these results suggest that Delta(9)-THC treatment increased viral load, as assessed by H1 mRNA levels, through a decrease in recruitment of macrophages and lymphocytes, particularly CD4(+) and CD8(+) T cells, to the lung...