ALEX A PEREZ-RIVERA

Summary

Affiliation: Michigan State University
Country: USA

Publications

  1. ncbi request reprint Increased reactivity of murine mesenteric veins to adrenergic agonists: functional evidence supporting increased alpha1-adrenoceptor reserve in veins compared with arteries
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan 48824, USA
    J Pharmacol Exp Ther 308:350-7. 2004
  2. ncbi request reprint Vascular reactivity of mesenteric arteries and veins to endothelin-1 in a murine model of high blood pressure
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, B 440 Life Sciences Building, East Lansing, MI 48824, USA
    Vascul Pharmacol 43:1-10. 2005
  3. ncbi request reprint Alpha-1B adrenoceptors mediate neurogenic constriction in mesenteric arteries of normotensive and DOCA-salt hypertensive mice
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, B 328 Life Sciences Building, East Lansing, MI 48824, USA
    Auton Neurosci 121:64-73. 2005
  4. pmc Differential contributions of alpha-1 and alpha-2 adrenoceptors to vasoconstriction in mesenteric arteries and veins of normal and hypertensive mice
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, USA
    Vascul Pharmacol 46:373-82. 2007

Research Grants

  1. Mechanisms of altered venous tone in hypertension
    ALEX PEREZ RIVERA; Fiscal Year: 2005

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Increased reactivity of murine mesenteric veins to adrenergic agonists: functional evidence supporting increased alpha1-adrenoceptor reserve in veins compared with arteries
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan 48824, USA
    J Pharmacol Exp Ther 308:350-7. 2004
    ..These data suggest that mesenteric veins express more alpha1-adrenoceptors than arteries, accounting for greater reactivity and resistance to desensitization compared with arteries...
  2. ncbi request reprint Vascular reactivity of mesenteric arteries and veins to endothelin-1 in a murine model of high blood pressure
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, B 440 Life Sciences Building, East Lansing, MI 48824, USA
    Vascul Pharmacol 43:1-10. 2005
    ..There was a prominent role for ET-mediated nitric oxide release in DOCA-salt but not SHAM arteries. In summary, these studies showed a differential regulation of ET-1 contractile mechanisms between murine mesenteric arteries and veins...
  3. ncbi request reprint Alpha-1B adrenoceptors mediate neurogenic constriction in mesenteric arteries of normotensive and DOCA-salt hypertensive mice
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, B 328 Life Sciences Building, East Lansing, MI 48824, USA
    Auton Neurosci 121:64-73. 2005
    ..Nerve-released NE acts primarily at alpha1B-and to a lesser extent at alpha1A-ARs in SHAM arteries whereas NE mediates neurogenic constrictions in DOCA-salt arteries by acting at alpha1B-ARs...
  4. pmc Differential contributions of alpha-1 and alpha-2 adrenoceptors to vasoconstriction in mesenteric arteries and veins of normal and hypertensive mice
    ALEX A PEREZ-RIVERA
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, USA
    Vascul Pharmacol 46:373-82. 2007
    ..This contribution of alpha(2)-ARs may account for the greater sensitivity of veins compared to arteries to the contractile effects of NE...

Research Grants1

  1. Mechanisms of altered venous tone in hypertension
    ALEX PEREZ RIVERA; Fiscal Year: 2005
    ..Answers to these questions will provide a basic understanding of venous function that could lead to better pharmacological approaches not only for hypertension treatment but also for any disease in which there is a vein dysfunction. ..