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Impact of epistasis and pleiotropy on evolutionary adaptationBjørn Ostman
Keck Graduate Institute of Applied Life Sciences, Claremont, CA 91711, USA
Proc Biol Sci 279:247-56. 2012..Our findings imply that the synergism between loci that interact epistatically is crucial for evolving genetic modules with high fitness, while too much ruggedness stalls the adaptive process...
