Research Topics
Genomes and GenesSpecies | Joel T NiggSummaryAffiliation: Michigan State University Country: USA Publications
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Publications
Attentional versus motor inhibition in adults with attention-deficit/hyperactivity disorderLaurie A Carr
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Neuropsychology 20:430-41. 2006..In the AB task, ADHD groups committed more errors but showed no convincing evidence of an abnormal blink. These results demonstrate clear effects on motoric inhibition but not attentional inhibition in adults with ADHD...- Neuropsychological executive functioning in children at elevated risk for alcoholism: findings in early adolescenceJoel T Nigg
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
J Abnorm Psychol 113:302-14. 2004..Results suggest that executive deficits are not part of the highest risk, antisocial pathway to alcoholism but that some executive function weaknesses may contribute to a secondary risk pathway... - An integrative theory of attention-deficit/ hyperactivity disorder based on the cognitive and affective neurosciencesJoel T Nigg
Department of Psychology, Michigan State University, East Lansing 48824 1116, USA
Dev Psychopathol 17:785-806. 2005..In turn, such decrement could lead to many of the phenotypic cognitive and neuropsychological features seen in children with ADHD... - Poor response inhibition as a predictor of problem drinking and illicit drug use in adolescents at risk for alcoholism and other substance use disordersJoel T Nigg
Department of Psychology, Michigan State University, East Lansing, MI 48824 116, USA
J Am Acad Child Adolesc Psychiatry 45:468-75. 2006..To evaluate the predictive power of executive functions, in particular, response inhibition, in relation to alcohol-related problems and illicit drug use in adolescence... - Temperament and developmental psychopathologyJoel T Nigg
Department of Psychology, Michigan State University, East Lansing, MI 48823 1116, USA
J Child Psychol Psychiatry 47:395-422. 2006..Anxiety disorders appear to result from the confluence of high negative emotionality and low effortful control. Hypotheses for future research are presented and limitations discussed... - Disinhibition and borderline personality disorderJoel T Nigg
Department of Psychology, Michigan State University, East Lansing, MI 48823 1116, USA
Dev Psychopathol 17:1129-49. 2005..We conclude by hypothesizing discrete developmental routes to BPD, based on different mechanism breakdowns, which would be amenable to empirical investigation at the cognitive or trait level of analysis... - Neuropsychologic theory and findings in attention-deficit/hyperactivity disorder: the state of the field and salient challenges for the coming decadeJoel T Nigg
Psychology Department, Michigan State University, East Lansing, Michigan 48824 1116, USA
Biol Psychiatry 57:1424-35. 2005..The next era must articulate multipathway, multilevel developmental accounts of ADHD that incorporate neuropsychologic effects... - Prenatal smoking exposure, low birth weight, and disruptive behavior disordersJoel T Nigg
Department of Psychology, Michifan State University, 115 Psychology Building, East Lansing, MI 48824 1116, USA
J Am Acad Child Adolesc Psychiatry 46:362-9. 2007..A key question concerns whether etiological contributors are shared across the broad range of disruptive psychopathology or are partially or largely distinct... - Causal heterogeneity in attention-deficit/hyperactivity disorder: do we need neuropsychologically impaired subtypes?Joel T Nigg
Department of Psychology, Michigan State University, East Lansing, Michigan 48824, USA
Biol Psychiatry 57:1224-30. 2005.... - Evaluating the endophenotype model of ADHD neuropsychological deficit: results for parents and siblings of children with ADHD combined and inattentive subtypesJoel T Nigg
Department of Psychology, 115 C Psychology Building, Michigan State University, East Lansing, MI 48824 1116, USA
J Abnorm Psychol 113:614-25. 2004..The authors conclude that a neurogenetic model of ADHD etiology is supportable only for a subset of executive functions and that neuropsychological heterogeneity warrants more examination in ADHD... - Executive functions and ADHD in adults: evidence for selective effects on ADHD symptom domainsJoel T Nigg
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
J Abnorm Psychol 114:706-17. 2005..Results were not accounted for by IQ, age, gender, education level, or comorbid disorders. Findings are discussed in terms of developmental and dual-process models of ADHD leading into adulthood... - Inhibitory processes in adults with persistent childhood onset ADHDJoel T Nigg
Department of Psychology, Michigan State University, East Lansing 48824 1117, USA
J Consult Clin Psychol 70:153-7. 2002.... - Big five dimensions and ADHD symptoms: links between personality traits and clinical symptomsJoel T Nigg
Department of Psychology, Michigan State University, East Lansing 48824 1117, USA
J Pers Soc Psychol 83:451-69. 2002..Results were replicated with self-reports and observer reports of personality in community and clinical samples. Findings support theoretical connections between personality traits and ADHD symptoms... 
Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive controlJoel T Nigg
Department of Psychology, Michigan State University, East Lansing, Lansing, MI 48824 1116, USA
Biol Psychiatry 63:325-31. 2008..We examine this relationship in children from a community sample exposed to average background levels of lead who have a diagnosis of ADHD that is established by clinical criteria...- Response inhibition and disruptive behaviors: toward a multiprocess conception of etiological heterogeneity for ADHD combined type and conduct disorder early-onset typeJoel T Nigg
Department of Psychology, Michigan State University, East Lansing, MI 48824 1117, USA
Ann N Y Acad Sci 1008:170-82. 2003..Examination of the correlates of behavioral inhibition in the subgroups with these inhibitory deficits may prove fruitful in clarifying the diverse routes to disruptive psychopathology in children... - Genotype and neuropsychological response inhibition as resilience promoters for attention-deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder under conditions of psychosocial adversityJoel Nigg
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Dev Psychopathol 19:767-86. 2007..Results illustrate potential neurobiological protective factors related to development of prefrontal cortex that may enable children to avoid developing ADHD and CD in the presence of psychosocial adversity... - Temperament and attention deficit hyperactivity disorder: the development of a multiple pathway modelJoel T Nigg
Psychology Department, Michigan State University, East Lansing 48824 1117, USA
J Clin Child Adolesc Psychol 33:42-53. 2004..We conclude with a theorized multiple process developmental model outlining alternate pathways to ADHD that warrant empirical investigation to better resolve etiological heterogeneity in ADHD... - Childhood and adolescent resiliency, regulation, and executive functioning in relation to adolescent problems and competence in a high-risk sampleMichelle M Martel
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Dev Psychopathol 19:541-63. 2007..Results are discussed in relation to recent trait models of regulation and the scaffolded development of competence and problems in childhood and adolescence... - External validation of bifactor model of ADHD: explaining heterogeneity in psychiatric comorbidity, cognitive control, and personality trait profiles within DSM-IV ADHDMichelle M Martel
Psychology Department, University of New Orleans, 2005 Geology and Psychology Building, 2000 Lakeshore Drive, New Orleans, LA 70148, USA
J Abnorm Child Psychol 39:1111-23. 2011..It is concluded that the bifactor model provides better explanation of heterogeneity within ADHD than DSM-IV ADHD symptom counts or subtypes... 
Personality mediation of genetic effects on Attention-Deficit/Hyperactivity DisorderMichelle M Martel
Psychology Department, University of New Orleans, 2005 Geology and Psychology Building, New Orleans, LA 70148, USA
J Abnorm Child Psychol 38:633-43. 2010..High neuroticism and low conscientiousness may be useful as early markers for children at risk for ADHD...- Behavioral control and resiliency in the onset of alcohol and illicit drug use: a prospective study from preschool to adolescenceMaria M Wong
Department of Psychology, Idaho State University, Pocatello, ID 83209 8112, USA
Child Dev 77:1016-33. 2006..32, SD=0.89). Children with slower rates of increase in behavioral control were more likely to use alcohol and other drugs in adolescence. Children with higher initial levels of resiliency were less likely to begin using alcohol... - Family psychiatric history evidence on the nosological relations of DSM-IV ADHD combined and inattentive subtypes: new data and meta-analysisJulie Ann Stawicki
Michigan State University, USA
J Child Psychol Psychiatry 47:935-45. 2006..We briefly suggest neuropsychological models that would account for this state of affairs and suggest future research to refine the nosology with these findings in mind... - Normative Symbol Digit Modalities Test performance in a community-based sampleLaura K Sheridan
Department of Psychology, Michigan State University, East Lansing, MI 48823, USA
Arch Clin Neuropsychol 21:23-8. 2006..In a multivariate model, these four variables did not impact test performance. These results support the utilization of the SDMT as a robust screening test for adult neuropsychological impairment... - Temperament pathways to childhood disruptive behavior and adolescent substance abuse: testing a cascade modelMichelle M Martel
Department of Psychology, University of New Orleans, 2005 Geology and Psychology Building, 2000 Lakeshore Drive, New Orleans, LA 70148, USA
J Abnorm Child Psychol 37:363-73. 2009..Some, but not all, temperament traits in childhood were related to adolescent substance abuse; these effects were mediated via inattentive/hyperactive and disruptive behaviors... - The adrenergic receptor alpha-2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHDIrwin D Waldman
Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
Cogn Affect Behav Neurosci 6:18-30. 2006..Implications of the results for evaluating the validity and utility of putative endophenotype measures and for finding candidate gene effects on ADHD are discussed... - Processing speed weakness in children and adolescents with non-hyperactive but inattentive ADHD (ADD)Timothy L Goth-Owens
Psychology Department, Michigan State University, East Lansing, MI 48824, USA
Child Neuropsychol 16:577-91. 2010..This subgroup may represent a distinct inattentive condition characterized by poor cognitive interference control and slow processing or output speed... - The dopamine receptor D4 gene (DRD4) moderates family environmental effects on ADHDMichelle M Martel
Psychology Department, University of New Orleans, 2000 Lakeshore Drive 2005 Geology and Psychology Building, New Orleans, LA 70148, USA
J Abnorm Child Psychol 39:1-10. 2011..DRD4 genotypes may interact with these proximal family environmental risk factors by increasing the individual's responsivity to environmental contingencies... - Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic reviewErik G Willcutt
Department of Psychology, University of Colorado, Boulder, Colorado 80309, USA
Biol Psychiatry 57:1336-46. 2005..Difficulties with EF appear to be one important component of the complex neuropsychology of ADHD... - Family adversity in DSM-IV ADHD combined and inattentive subtypes and associated disruptive behavior problemsCarla A Counts
Department of Psychology, Florida State University, Tallahassee, USA
J Am Acad Child Adolesc Psychiatry 44:690-8. 2005..CONCLUSIONS: Family adversity is related to ADHD combined type in children and may be related specifically to ADHD symptoms in addition to conduct disorder symptoms... - Child ADHD and personality/temperament traits of reactive and effortful control, resiliency, and emotionalityMichelle M Martel
Michigan State University, Michigan, USA
J Child Psychol Psychiatry 47:1175-83. 2006..We investigated this in terms of key personality/temperament traits of Reactive and Effortful Control, Resiliency, and Emotionality... - The structure of childhood disruptive behaviorsMichelle M Martel
Department of Psychology, University of New Orleans, New Orleans, LA 70148, USA
Psychol Assess 22:816-26. 2010..It is concluded that a bifactor model of childhood disruptive behaviors is superior to existing models and may help explain common patterns of comorbidity between ADHD and ODD... - Gene x environment interactions for ADHD: synergistic effect of 5HTTLPR genotype and youth appraisals of inter-parental conflictMolly Nikolas
Department of Psychology, Michigan State University, East Lansing, Michigan, USA
Behav Brain Funct 6:23. 2010.... - Childhood sleep problems, response inhibition, and alcohol and drug outcomes in adolescence and young adulthoodMaria M Wong
Department of Psychology, Idaho State University, Pocatello, Idaho 83209 8112, USA
Alcohol Clin Exp Res 34:1033-44. 2010..We also tested whether adolescent sleep problems and poor response inhibition mediated the relationship between childhood sleep problems and substance (alcohol and drug) outcomes in young adulthood... - Factor structure of the Children's Perception of Interparental Conflict Scale for studies of youths with externalizing behavior problemsJoel T Nigg
Department of Psychology, Michigan State University, USA
Psychol Assess 21:450-6. 2009..The authors concluded that the item-based 4-factor solution to the CPIC is preferable to the 9-factor or 3-factor formulation... - Cognitive control and attentional selection in adolescents with ADHD versus ADDLaurie Carr
Department of Psychology, Michigan State University, USA
J Clin Child Adolesc Psychol 39:726-40. 2010..ADHD-combined showed greater weakness in response inhibition, as manifest in the antisaccade task. Combining tasks yielded an interaction differentiating group performance on the two tasks... - How do trait dimensions map onto ADHD symptom domains?Michelle M Martel
Psychology Department, University of New Orleans, New Orleans, LA, USA
J Abnorm Child Psychol 37:337-48. 2009..Personality traits appear to map onto ADHD symptoms in a meaningful manner consistent with a dual-process model of temperament and ADHD... - Revisiting the latent structure of ADHD: is there a 'g' factor?Michelle M Martel
Psychology Department, University of New Orleans, USA
J Child Psychol Psychiatry 51:905-14. 2010..Yet formal testing of models that would accommodate such assumptions using modern methods (e.g., second-order factor and bifactor models) has been largely lacking... - A person-centered personality approach to heterogeneity in attention-deficit/hyperactivity disorder (ADHD)Michelle M Martel
Psychology Department, University of New Orleans, New Orleans, LA 70148, USA
J Abnorm Psychol 119:186-96. 2010..A person-centered personality approach may be one promising way to capture homogeneous subgroups within the ADHD population... - Sex differences in the pathway from low birth weight to inattention/hyperactivityMichelle M Martel
Department of Psychology, Michigan State University, 43 Psychology Building, East Lansing, MI 48823 1116, USA
J Abnorm Child Psychol 35:87-96. 2007..Sex differences in the associated features of attention symptoms may reflect partially distinct etiological pathways... - Deficient attention is hard to find: applying the perceptual load model of selective attention to attention deficit hyperactivity disorder subtypesCynthia L Huang-Pollock
Department of Psychology, Pennsylvania State University, State College, University Park, PA 16802, USA
J Child Psychol Psychiatry 46:1211-8. 2005..Whether selective attention is a primary deficit in childhood Attention Deficit Hyperactivity Disorder (ADHD) remains in active debate... - Cognitive inhibition and working memory in attention-deficit/hyperactivity disorderPaul E Engelhardt
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
J Abnorm Psychol 117:591-605. 2008..The results challenge a unitary inhibition problem in ADHD and suggest inhibition problems do not extend to cognitive suppression in this age range... - Neuropsychological executive functions and DSM-IV ADHD subtypesJoel T Nigg
Department of Psychology, Michigan State University, East Lansing 48824-1117, USA
J Am Acad Child Adolesc Psychiatry 41:59-66. 2002..In the case of boys, the two subtypes may be distinguished by the specificity of motor inhibition deficits to ADHD-C... - Single dissociation findings of ADHD deficits in vigilance but not anterior or posterior attention systemsCynthia L Huang-Pollock
Department of Psychology, Pennsylvania State University, University Park, PA 16802, USA
Neuropsychology 20:420-9. 2006..However, consistent with previous meta-analytic work, there was no evidence for anterior or posterior system orienting dysfunctions in either subtype... - Masculinized finger-length ratios of boys, but not girls, are associated with attention-deficit/hyperactivity disorderMichelle M Martel
Department of Psychology, Michigan State University, East Lansing 48823 1116, USA
Behav Neurosci 122:273-81. 2008..It is concluded that prenatal, organizational effects of gonadal hormones may play a role in the development of ADHD and contribute to explaining sex differences in the prevalence rates of this childhood disorder... - Axis I and II comorbidity in adults with ADHDTorri W Miller
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
J Abnorm Psychol 116:519-28. 2007..Fourth, ADHD incrementally accounted for clinician-rated global assessment of functioning scores above and beyond comorbid conditions or symptoms on either Axis I or Axis II. Results further inform nosology of ADHD in adults... - Executive function in adolescents with ADHDMichelle Martel
Department of Psychology, Michigan State University, East Laning, 48824 1116, USA
J Am Acad Child Adolesc Psychiatry 46:1437-44. 2007..The aim of this study was to clarify executive function weakness in attention-deficit/hyperactivity disorder (ADHD) during adolescence and determine the specificity of executive function weakness to ADHD symptom domains... - Potential hormonal mechanisms of attention-deficit/hyperactivity disorder and major depressive disorder: a new perspectiveMichelle M Martel
Psychology Department, University of New Orleans, LA 70148, USA
Horm Behav 55:465-79. 2009..Hypotheses from these theories are evaluated based on the current available literature, and limitations of, and future directions for, this literature are discussed... - Executive functions and adaptive functioning in young adult attention-deficit/hyperactivity disorderGillian M Stavro
Department of Psychology, Michigan State University, East Lansing, Michigan 48824 1116, USA
J Int Neuropsychol Soc 13:324-34. 2007.... - Diversity in pathways to common childhood disruptive behavior disordersMichelle M Martel
Psychology Department, University of New Orleans, 2000 Lakeshore Drive, 2005 Geology and Psychology Building, New Orleans, LA, 70148, USA
J Abnorm Child Psychol 40:1223-36. 2012..Thus, ODD and ADHD appear to demonstrate somewhat distinct correlational associations between etiological factors and mechanisms consistent with pathway models using a multiple-level-of-analysis approach... - Familial psychiatric disorders in child DSM-IV ADHD: moderation by child genderJulieann Stawicki
Department of Psychology, Michigan State University, 4700 E Hagadorn Road, Suite 110, East Lansing, MI 48824, USA
Ann N Y Acad Sci 1008:293-6. 2003..Excess parent psychopathology was observed for parents of boys--primarily due to psychopathology in fathers--score potential gender differences in development of ADHD... - Current issues in the diagnosis of attention deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorderPaul J Frick
Department of Psychology, University of New Orleans, New Orleans, Louisiana 70148, USA
Annu Rev Clin Psychol 8:77-107. 2012..Finally, for CD, enhancing the current subtypes related to age of onset and integrating callous-unemotional traits into the diagnostic criteria are identified as key issues for improving classification... - Development of selective attention: perceptual load influences early versus late attentional selection in children and adultsCynthia L Huang-Pollock
Department of Psychology, Michigan State University, East Lansing 48824 1117, USA
Dev Psychol 38:363-75. 2002..Overall, children initiated early selection at lower loads to compensate for immature anterior-system interference control processes... - Emotion regulation via the autonomic nervous system in children with attention-deficit/hyperactivity disorder (ADHD)Erica D Musser
Psychology Department, University of Oregon, 1227 University of Oregon, Eugene, OR 97403, USA
J Abnorm Child Psychol 39:841-52. 2011..No group differences in sympathetic activity (PEP) were observed. It is concluded ADHD in childhood is associated with abnormal parasympathetic mechanisms involved in emotion regulation... - Searching for the attention deficit in attention deficit hyperactivity disorder: the case of visuospatial orientingCynthia L Huang-Pollock
Psychology Department, Michigan State University, East Lansing, MI 48824 1117, USA
Clin Psychol Rev 23:801-30. 2003.... - Attention deficit hyperactivity disorder in African American children: what can be concluded from the past ten years?Torri W Miller
Michigan State University, Psychology Building, East Lansing, MI 48824, USA
Clin Psychol Rev 29:77-86. 2009..Findings highlight the need for more investigation and awareness of relevant cultural issues to inform a culturally competent approach to assessment, diagnosis, and treatment of ADHD in African Americans... - SNP discovery and haplotype analysis in the segmentally duplicated DRD5 coding regionDonna J E Housley
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, USA
Ann Hum Genet 73:274-82. 2009..The simple and relatively inexpensive method presented herein allows for convenient analysis of sequence variation in DRD5 and can be easily adapted to other duplicated genomic regions in order to obtain good quality sequence data... - Parenting practices and attention-deficit/hyperactivity disorder: new findings suggest partial specificity of effectsBrandi Ellis
135 Psychology Building, Michigan State University, East Lansing, MI 48824 1116, USA
J Am Acad Child Adolesc Psychiatry 48:146-54. 2009..Examine the relations of attention-deficit/hyperactivity disorder (ADHD) diagnosis and symptom domains with parenting practices... - ADHD, lead exposure and prevention: how much lead or how much evidence is needed?Joel T Nigg
Expert Rev Neurother 8:519-21. 2008 - Affective circuitry and risk for alcoholism in late adolescence: differences in frontostriatal responses between vulnerable and resilient children of alcoholic parentsMary M Heitzeg
Department of Psychiatry, The University of Michigan, Ann Arbor, Michigan 48109 0720, USA
Alcohol Clin Exp Res 32:414-26. 2008.... - Smoking is associated with neurocognitive deficits in alcoholismJennifer M Glass
Department of Psychiatry, University of Michigan, Addiction Research Center, 2025 Traverwood, Suite A, Ann Arbor, 48105 2194, USA
Drug Alcohol Depend 82:119-26. 2006.... - Inattention/hyperactivity and aggression from early childhood to adolescence: heterogeneity of trajectories and differential influence of family environment characteristicsJennifer M Jester
University of Michigan, Department of Psychiatry, Addiction Research Center, 400 E Eisenhower Parkway, Suite 2A, Ann Arbor, MI 48108, USA
Dev Psychopathol 17:99-125. 2005..The implications of these findings for the development of inattention/hyperactivity and for the development of risk for the emergence of substance use disorders are discussed... - Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD?Alysa E Doyle
Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Child Psychol Psychiatry 46:774-803. 2005..Thus far, potential endophenotypes for ADHD have not been systematically studied... - Predicting risky drinking outcomes longitudinally: what kind of advance notice can we get?Robert A Zucker
Department of Psychiatry, University of Michigan Addiction Research Center, Ann Arbor, Michigan 48105, USA
Alcohol Clin Exp Res 30:243-52. 2006..Finally, Robert Zucker examines the degree to which the core symposium questions are answered and comments on next step research and clinical practice changes that are called for by these findings... - New potential leads in the biology and treatment of attention deficit-hyperactivity disorderB J Casey
Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, New York 10021, USA
Curr Opin Neurol 20:119-24. 2007..This review highlights recent neuroimaging and genetic studies of attention deficit-hyperactivity disorder that may inform biologically targeted interventions and treatments... - Effects of sex hormones on associative learning in spontaneously hypertensive ratsDavid J Bucci
Department of Psychological and Brain Sciences, Dartmouth College, 6207 Moore Hall, Hanover, NH 03755, USA
Physiol Behav 93:651-7. 2008..To the extent that SHR serves as a model of ADHD in humans, the influence of steroids on associative learning may play a role in the expression of ADHD-like behaviors...
Research Grants
- Hormones in Sex-different Developmental PsychopathologyJoel Nigg; Fiscal Year: 2007....