R E Lenski

Summary

Affiliation: Michigan State University
Country: USA

Publications

  1. pmc Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7 using IS elements as molecular markers
    Dominique Schneider
    Laboratoire Plasticité et Expression des Génomes Microbiens, CNRS FRE2383, Universite Joseph Fourier, Grenoble, Fance
    BMC Microbiol 2:18. 2002
  2. ncbi request reprint Bacterial evolution and the cost of antibiotic resistance
    R E Lenski
    Center for Microbial Ecology, Michigan State University 48824, USA
    Int Microbiol 1:265-70. 1998
  3. ncbi request reprint Genome complexity, robustness and genetic interactions in digital organisms
    R E Lenski
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 400:661-4. 1999
  4. ncbi request reprint Punctuated evolution caused by selection of rare beneficial mutations
    S F Elena
    Center for Microbial Ecology, Michigan State University, East Lansing, 48824, USA
    Science 272:1802-4. 1996
  5. pmc Long-term experimental evolution in Escherichia coli. IV. Targets of selection and the specificity of adaptation
    M Travisano
    Center for Microbial Ecology, Michigan State University, East Lansing 48824 1325, USA
    Genetics 143:15-26. 1996
  6. pmc Genome-wide mutational diversity in an evolving population of Escherichia coli
    J E Barrick
    Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA
    Cold Spring Harb Symp Quant Biol 74:119-29. 2009
  7. ncbi request reprint The population genetics of ecological specialization in evolving Escherichia coli populations
    V S Cooper
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 407:736-9. 2000
  8. pmc Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B
    V S Cooper
    Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824, USA
    J Bacteriol 183:2834-41. 2001
  9. ncbi request reprint Test of synergistic interactions among deleterious mutations in bacteria
    S F Elena
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 390:395-8. 1997
  10. pmc Pervasive compensatory adaptation in Escherichia coli
    F B Moore
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Proc Biol Sci 267:515-22. 2000

Detail Information

Publications18

  1. pmc Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7 using IS elements as molecular markers
    Dominique Schneider
    Laboratoire Plasticité et Expression des Génomes Microbiens, CNRS FRE2383, Universite Joseph Fourier, Grenoble, Fance
    BMC Microbiol 2:18. 2002
    ..Here, we map most of the IS elements in E. coli B and compare their locations with the published genomes of K-12 and O157:H7...
  2. ncbi request reprint Bacterial evolution and the cost of antibiotic resistance
    R E Lenski
    Center for Microbial Ecology, Michigan State University 48824, USA
    Int Microbiol 1:265-70. 1998
    ..As a consequence, it becomes increasingly difficult to eliminate resistant genotypes simply by suspending the use of antibiotics...
  3. ncbi request reprint Genome complexity, robustness and genetic interactions in digital organisms
    R E Lenski
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 400:661-4. 1999
    ..Frequent interactions among mutations have also been seen in bacteria, fungi and fruitflies. Our findings support the view that interactions are a general feature of genetic systems...
  4. ncbi request reprint Punctuated evolution caused by selection of rare beneficial mutations
    S F Elena
    Center for Microbial Ecology, Michigan State University, East Lansing, 48824, USA
    Science 272:1802-4. 1996
    ..This experiment shows that the most elementary processes in population genetics can give rise to punctuated evolution dynamics...
  5. pmc Long-term experimental evolution in Escherichia coli. IV. Targets of selection and the specificity of adaptation
    M Travisano
    Center for Microbial Ecology, Michigan State University, East Lansing 48824 1325, USA
    Genetics 143:15-26. 1996
    ....
  6. pmc Genome-wide mutational diversity in an evolving population of Escherichia coli
    J E Barrick
    Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA
    Cold Spring Harb Symp Quant Biol 74:119-29. 2009
    ..Still finer-resolution details of the structure of genetic variation and how it changes over time in microbial evolution experiments will enable new applications and quantitative tests of population genetic theory...
  7. ncbi request reprint The population genetics of ecological specialization in evolving Escherichia coli populations
    V S Cooper
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 407:736-9. 2000
    ..Thus, antagonistic pleiotropy appears more important than mutation accumulation for the decay of unused catabolic functions in these populations...
  8. pmc Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B
    V S Cooper
    Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824, USA
    J Bacteriol 183:2834-41. 2001
    ....
  9. ncbi request reprint Test of synergistic interactions among deleterious mutations in bacteria
    S F Elena
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 390:395-8. 1997
    ..Several pairs exhibit significant interactions for fitness, but they are antagonistic as often as they are synergistic. These results do not support the mutational deterministic hypothesis for the evolution of sex...
  10. pmc Pervasive compensatory adaptation in Escherichia coli
    F B Moore
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Proc Biol Sci 267:515-22. 2000
    ..coil genome which demands further study from both genetic and physiological perspectives...
  11. ncbi request reprint The fate of competing beneficial mutations in an asexual population
    P J Gerrish
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Genetica 102:127-44. 1998
    ..Based on (2) and (3), we were able to estimate the beneficial mutation rate and the distribution of mutational effects from changes in mean fitness in an evolving E. coli population...
  12. ncbi request reprint Diminishing returns from mutation supply rate in asexual populations
    J A Arjan
    Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824, USA
    Science 283:404-6. 1999
    ..These experiments also demonstrate a "speed limit" on adaptive evolution in asexual populations, one that is independent of the mutation supply rate...
  13. ncbi request reprint Evolution of thermal dependence of growth rate of Escherichia coli populations during 20,000 generations in a constant environment
    V S Cooper
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Evolution 55:889-96. 2001
    ..Antagonistic pleiotropy therefore is more likely to be responsible for the evolution of thermal specialization observed in maximum growth rate...
  14. ncbi request reprint Developmental cheating in the social bacterium Myxococcus xanthus
    G J Velicer
    Department of Biochemistry, Michigan State University, East Lansing 48824, USA
    Nature 404:598-601. 2000
    ..The ease of finding anti-social behaviours suggests that cheaters may be common in natural populations of M. xanthus...
  15. pmc Parallel and divergent genotypic evolution in experimental populations of Ralstonia sp
    C H Nakatsu
    NSF Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824, USA
    J Bacteriol 180:4325-31. 1998
    ..The common and uncommon genetic changes observed show that both parallel and divergent genotypic evolution occurred in replicate populations of this bacterium...
  16. pmc Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli
    S K Remold
    Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824, USA
    Proc Natl Acad Sci U S A 98:11388-93. 2001
    ..More generally, our findings demonstrate that GxE interactions can be quite common, even for genotypes that differ by only one mutation and in environments differing by only a single factor...
  17. ncbi request reprint Rapid phenotypic change and diversification of a soil bacterium during 1000 generations of experimental evolution
    M S Riley
    Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824, USA
    Microbiology 147:995-1006. 2001
    ..This diversity may represent a set of equally probable adaptive solutions to the selective environment; it may also arise from the chance fixation of non-adaptive mutations that hitchhiked with a more limited set of beneficial mutations...
  18. doi request reprint Historical and contingent factors affect re-evolution of a complex feature lost during mass extinction in communities of digital organisms
    G Yedid
    Ecology, Evolutionary Biology, and Behaviour Program, Michigan State University, East Lansing, MI, USA
    J Evol Biol 21:1335-57. 2008
    ..Our results demonstrate that stochastic, historical, genomic and ecological factors can lead to constraints on further adaptation, and facilitate or hinder re-evolution of a complex feature...