Research Topics
| K L KlumpSummaryAffiliation: Michigan State University Country: USA Publications
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Publications
Differential heritability of eating attitudes and behaviors in prepubertal versus pubertal twinsKelly L Klump
Department of Psychology, Michigan State University, 129 Psychology Research Building, East Lansing, MI 48824, USA
Int J Eat Disord 33:287-92. 2003..Differential heritability of eating pathology in prepubertal, pubertal, and 17-year-old twins was examined using a population-based twin sample...- Obsessions and compulsions in anorexia nervosa subtypesKatherine A Halmi
New York Presbyterian Hospital Westchester Division, Weill Medical College of Cornell University, 21 Bloomingdale Road, White Plains, NY 10605, USA
Int J Eat Disord 33:308-19. 2003..We examined the type and frequency of characteristic OCD obsessions and compulsions in a large sample of AN patients... - Personality in men with eating disordersD Blake Woodside
Program for Eating Disorders, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
J Psychosom Res 57:273-8. 2004..This study compares personality variables of men with eating disorders to women with eating disorders... 
Linkage analysis of anorexia and bulimia nervosa cohorts using selected behavioral phenotypes as quantitative traits or covariatesSilviu-Alin Bacanu
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213-2593, USA
Am J Med Genet B Neuropsychiatr Genet 139:61-8. 2005..3); for covariate-based linkage analysis, five suggestive signals (for BMI at 4q13.1, for CM at 11p11.2 and 17q25.1, and for OBF at 17q25.1 and 15q26.2). Overlap between the two cohorts was minimal for substantial linkage signals...- The Minnesota Eating Behavior Survey: a brief measure of disordered eating attitudes and behaviorsKristin M von Ranson
Department of Psychology, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4
Eat Behav 6:373-92. 2005..This questionnaire has promise as a screening and assessment measure for eating disturbance in cross-sectional and longitudinal research involving individuals of a wide range of ages... 
Binge eating proneness emerges during puberty in female rats: a longitudinal studyKelly L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
J Abnorm Psychol 120:948-55. 2011..These findings provide strong confirming evidence for the importance of biological risk factors in developmental trajectories of binge eating risk across adolescence...- The effects of puberty on genetic risk for disordered eating: evidence for a sex differenceK L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Psychol Med 42:627-37. 2012..The current study was the first to examine this possibility in a sample of 1006 male and female twins from the Michigan State University Twin Registry... - Genetic and environmental influences on disordered eating: An adoption studyKelly L Klump
Department of Psychology, Michigan State University, East Lansing, 48824 1116, USA
J Abnorm Psychol 118:797-805. 2009..Shared environmental factors did not contribute significantly to any disordered eating symptom. Our findings bolster those from twin studies and provide critical evidence of significant genetic effects on disordered eating symptoms... - A review and primer of molecular genetic studies of anorexia nervosaKelly L Klump
Department of Psychology, Michigan State University, East Lansing, Michigan 48824, USA
Int J Eat Disord 37:S43-8; discussion S87-9. 2005..Nonetheless, future molecular genetic research would benefit from larger and more sustained investigations of candidate genes in homogeneous phenotypes... - Preliminary evidence that gonadal hormones organize and activate disordered eatingKelly L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Psychol Med 36:539-46. 2006..This preliminary set of studies examined these effects by investigating relationships between eating disorder symptoms, prenatal testosterone exposure, and adult levels of estrogen in women... - Personality characteristics of women before and after recovery from an eating disorderKelly L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Psychol Med 34:1407-18. 2004..This study compares personality characteristics among women who are ill with eating disorders, recovered from eating disorders, and those without eating or other Axis I disorder pathology... - Ovarian hormones and binge eating: exploring associations in community samplesK L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Psychol Med 38:1749-57. 2008..However, no study has examined these relationships in a non-clinical sample, despite the need for these data for designing risk-factor studies... - The Michigan State University Twin Registry (MSUTR): genetic, environmental and neurobiological influences on behavior across developmentKelly L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Twin Res Hum Genet 9:971-7. 2006..To date, we have collected data on over 1000 twins, with additional data collections underway. This article provides an overview of the newly developed MSUTR and describes current and future research directions... - Puberty moderates genetic influences on disordered eatingKelly L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Psychol Med 37:627-34. 2007..The purpose of the present study therefore was to directly examine this possibility by investigating whether pubertal development moderates genetic influences on disordered eating... - Changes in genetic and environmental influences on disordered eating across adolescence: a longitudinal twin studyKelly L Klump
Department of Psychology, Michigan State University, 107B Psychology Building, East Lansing, MI 48824 1116, USA
Arch Gen Psychiatry 64:1409-15. 2007..Previous research suggests substantial increases in genetic effects on disordered eating across adolescence. Unfortunately, these studies were cross-sectional and focused primarily on early (age 11 years) vs late (age 17 years) adolescence... - Age differences in genetic and environmental influences on weight and shape concernsKelly L Klump
Department of Psychology, Michigan State University, East Lansing, Michigan 48824 1116, USA
Int J Eat Disord 43:679-88. 2010..The goal of this study was to investigate these age differences in preadolescent, adolescent, young adult, and mid-adult twins... - Genetic relationships between personality and eating attitudes and behaviorsKelly L Klump
Department of Psychology, Michigan State University, East Lansing 48824, USA
J Abnorm Psychol 111:380-9. 2002..MPQ personality characteristics may represent only some of several genetic risk factors for eating pathology... - Preliminary evidence that estradiol moderates genetic influences on disordered eating attitudes and behaviors during pubertyK L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Psychol Med 40:1745-53. 2010..The aim of this pilot study was to examine whether estradiol levels moderate genetic influences on disordered eating during puberty... - Does environment matter? A review of nonshared environment and eating disordersKelly L Klump
Department of Psychology, Michigan State University, East Lansing, Michigan 48824, USA
Int J Eat Disord 31:118-35. 2002..We review studies highlighting the importance of nonshared factors for the development of eating disorders and suggest areas for future research... - The effects of ovariectomy on binge eating proneness in adult female ratsKelly L Klump
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Horm Behav 59:585-93. 2011..g., organizational hormone effects or hormone-independent effects) determine the expression of binge eating phenotypes... - Puberty and the genetic diathesis of disordered eating attitudes and behaviorsKristen M Culbert
Department of Psychology, Michigan State University, East Lansing, 48824 1116, USA
J Abnorm Psychol 118:788-96. 2009..Findings highlight the potentially important role of puberty in the genetic diathesis of disordered eating attitudes and behaviors and the need to use early indicators of pubertal status in studies of developmental effects... - The death(s) of close friends and family moderate genetic influences on symptoms of major depressive disorder in adolescentsS Gheyara
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Psychol Med 41:721-9. 2011..However, it is unclear whether these results persist when controlling for the possibility of confounding active gene-environment correlations (rGE)... - A longitudinal investigation of the relationship between disordered eating attitudes and behaviors and parent-child conflict: a monozygotic twin differences designAlexia Spanos
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
J Abnorm Psychol 119:293-9. 2010..Findings suggest differences in parent-child conflict between genetically identical twins may be a consequence of, rather than a risk factor for, differences in disordered eating... - The road less traveled: Associations between externalizing behaviors and eating pathologyJennifer D Slane
Department of Psychology, Michigan State University, East Lansing, Michigan, USA
Int J Eat Disord 43:149-60. 2010..The current study investigated sex differences in associations between internalizing and externalizing symptoms and disordered eating... - Genetic and environmental influences on 2D:4D finger length ratios: a study of monozygotic and dizygotic male and female twinsKyle L Gobrogge
Department of Psychology, Florida State University, Tallahassee, FL, USA
Arch Sex Behav 37:112-8. 2008..Findings suggest greater similarity between 2D:4D ratios in MZ relative to DZ twins that can be accounted for by genetic and nonshared environmental factors... - Shared transmission of eating disorders and anxiety disordersPamela K Keel
Department of Psychology, University of Iowa, Iowa City, Iowa 55242, USA
Int J Eat Disord 38:99-105. 2005..Using twins from the population-based Minnesota Twin Family Study (MTFS), we examined comorbidity and shared transmission between eating pathology and these disorders... - Do weight and shape concerns exhibit genetic effects? Investigating discrepant findingsAlexia Spanos
Department of Psychology, Michigan State University, East Lansing, MI, USA
Int J Eat Disord 43:29-34. 2010..The present study sought to resolve these discrepancies by examining the heritability of both types of weight and shape concerns in a young adult twin sample... - Prenatal hormone exposure and risk for eating disorders: a comparison of opposite-sex and same-sex twinsKristen M Culbert
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
Arch Gen Psychiatry 65:329-36. 2008..Prenatal testosterone exposure is a promising candidate, since it masculinizes behavior in animals and humans via its permanent effects on the central nervous system... - Negative affect as a mediator of the relationship between weight-based teasing and binge eating in adolescent girlsJessica L Suisman
Department of Psychology, Michigan State University, East Lansing, MI, USA
Eat Behav 9:493-6. 2008..Results suggest that increases in negative affect are one way in which weight-based teasing leads to binge eating in girls. Future studies should examine additional mediators and assess possible clinical applications of these findings... - Genes, personality, and attachment in adults: a multivariate behavioral genetic analysisM Brent Donnellan
Department of Psychology, Michigan State University, East Lansing, MI 48823, USA
Pers Soc Psychol Bull 34:3-16. 2008.... - Predictors of alcohol problems in college women: the role of depressive symptoms, disordered eating, and family history of alcoholismZaje A T Harrell
Department of Psychology, Michigan State University, Department of Psychology, Psychology Building 134B, East Lansing, MI 48824 1116, United States
Addict Behav 34:252-7. 2009..However, there was a significant interaction between disordered eating and FHA; disordered eating was associated with alcohol problems in those with a positive FHA. The implications for high-risk subgroups of college women are discussed... - The etiological moderation of aggressive and nonaggressive antisocial behavior by ageS Alexandra Burt
Department of Psychology, Michigan State University, East Lansing, MI 48824, United States of America
Twin Res Hum Genet 12:343-50. 2009.... - The influence of gender and puberty on the heritability of disordered eating symptomsKristen M Culbert
Department of Psychology, Michigan State University, 43 Psychology Building, East Lansing, MI 48824 1116, USA
Curr Top Behav Neurosci 6:177-85. 2011..Although much more research is needed to elucidate specific mechanisms, gonadal hormones may be promising candidates for understanding sex and developmental effects and the ways in which genes exert their influence on disordered eating... - An association of early puberty with disordered eating and anxiety in a population of undergraduate women and menJulia L Zehr
Neuroscience Program, Michigan State University, East Lansing, MI 48824 1116, USA
Horm Behav 52:427-35. 2007..The fact that early puberty was associated with increased eating and anxiety symptoms in both sexes suggests that puberty may influence these symptoms through both biological and psychosocial mechanisms... - The evolving genetic foundations of eating disordersK L Klump
Department of Psychology, Michigan State University, East Lansing, Michigan, USA
Psychiatr Clin North Am 24:215-25. 2001..These studies likely will provide invaluable information regarding the appropriate phenotypes to be included in genetic studies and the genes with the most influence on the development of these disorders... - Impulsivity as an underlying factor in the relationship between disordered eating and sexual behaviorKristen M Culbert
Department of Psychology, Michigan State University, East Lansing, Michigan 48824-1116, USA
Int J Eat Disord 38:361-6. 2005..CONCLUSION: Compensatory behaviors and increased sexual activity likely represent risky behaviors that are influenced by impulsivity levels... - The possible influence of impulsivity and dietary restraint on associations between serotonin genes and binge eatingSarah E Racine
Department of Psychology, Michigan State University, 107B Psychology Building, East Lansing, Michigan 48824 1116, USA
J Psychiatr Res 43:1278-86. 2009.... - Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sampleK L Klump
Department of Psychology, Michigan State University, East Lansing, USA
Psychol Med 31:737-40. 2001..CONCLUSIONS: Findings support previous research indicating significant genetic and non-shared environmental influences on AN syndromes... - Are eating disorders culture-bound syndromes? Implications for conceptualizing their etiologyPamela K Keel
Department of Psychology, Harvard University, USA
Psychol Bull 129:747-69. 2003..Thus, heritability estimates for BN may show greater variability cross-culturally than heritability estimates for AN, and the genetic bases of these disorders may be associated with differential pathoplasticity... - Personality traits in women with anorexia nervosa: evidence for a treatment-seeking bias?Patrick S Perkins
Department of Psychology, Michigan State University, East Lansing, Michigan 48824, USA
Int J Eat Disord 37:32-7. 2005..The current study used a population-based sample to compare the personality characteristics of women with AN who sought treatment versus those who did not... - Stigmatization of eating disorders: a controlled study of the effects of the television show StarvedShawn N Katterman
Department of Psychology, Drexel University, Philadelphia, Pennsylvania, USA
Eat Disord 18:153-64. 2010..Future research should examine prolonged exposure and other potential sources of these negative attitudes... - Factor structure of the Children's Perception of Interparental Conflict Scale for studies of youths with externalizing behavior problemsJoel T Nigg
Department of Psychology, Michigan State University, USA
Psychol Assess 21:450-6. 2009..The authors concluded that the item-based 4-factor solution to the CPIC is preferable to the 9-factor or 3-factor formulation... - Season of birth and disordered eating in female college studentsMelissa A Munn
Department of Psychology, Michigan State University, East Lansing, Michigan 48824, USA
Int J Eat Disord 34:343-8. 2003..DISCUSSION: The lack of significant differences across birth periods suggests that season of birth effects may not generalize to general disordered eating characteristics in nonclinical samples... - Symptom fluctuation in eating disorders: correlates of diagnostic crossoverFederica Tozzi
Department of Psychiatry, CB 7160, University of North Carolina at Chapel Hill, Neurosciences Hospital, Chapel Hill, NC 27599-7160l, USA
Am J Psychiatry 162:732-40. 2005..These results indicate that personality and family characteristics may influence the course of eating disorders and may be informative for planning interventions... - Symptom profile of major depressive disorder in women with eating disordersFernando Fernandez Aranda
Department of Psychiatry, University Hospital of Bellvitge, Barcelona, Spain
Aust N Z J Psychiatry 41:24-31. 2007..The temporal relation between EDs and MDD onset was analyzed to determine differences in the course and nature of MDD when experienced prior to versus after the onset of the ED... - Linkage analysis of anorexia nervosa incorporating behavioral covariatesBernie Devlin
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213 2593, USA
Hum Mol Genet 11:689-96. 2002..50, P = 0.00035). By comparing our results to those implemented using more standard linkage methods, we find the covariates convey substantial information for the linkage analysis... - Alcohol use disorder comorbidity in eating disorders: a multicenter studyCynthia M Bulik
Department of Psychiatry, University of North Carolina at Chapel Hill, 27599 7160, USA
J Clin Psychiatry 65:1000-6. 2004..Our aim was to explore the nature of the co-morbid relation between AUDs and eating disorders in a large and phenotypically well-characterized group of individuals... - Genetic analysis of bulimia nervosa: methods and sample descriptionWalter H Kaye
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Int J Eat Disord 35:556-70. 2004..The current study presents the clinical characteristics of this sample as well as a description of the study methodology... - Selection of eating-disorder phenotypes for linkage analysisCynthia M Bulik
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Med Genet B Neuropsychiatr Genet 139:81-7. 2005..Linkage results appear in a subsequent report. Our report lays out a systematic roadmap for utilizing a rich set of phenotypes for genetic analyses, including the selection of linkage methods paired to those phenotypes... - The relation among perfectionism, obsessive-compulsive personality disorder and obsessive-compulsive disorder in individuals with eating disordersKatherine A Halmi
New York Presbyterian Hospital-Westchester Division, Weill Medical College of Cornell University, White Plains, New York, USA
Int J Eat Disord 38:371-4. 2005..The pairing of perfectionism with OCPD may be a relevant core behavioral feature underlying vulnerability to ED... - Genetic epidemiology, endophenotypes, and eating disorder classificationCynthia M Bulik
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
Int J Eat Disord 40:S52-60. 2007..To explore how genetic epidemiology has informed the identification of endophenotypes and how endophenotypes may inform future classification of eating disorders... - Patterns of menstrual disturbance in eating disordersAndréa Poyastro Pinheiro
Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
Int J Eat Disord 40:424-34. 2007..To describe menstrual disturbance in eating disorders (ED)... - Relationships between features associated with vomiting in purging-type eating disordersLauren Reba
Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina 27599-7160, USA
Int J Eat Disord 38:287-94. 2005..Specifically targeting treatment to decrease duration of exposure to this dangerous symptom continues to be an important clinical objective... - Suicide attempts in anorexia nervosaCynthia M Bulik
Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
Psychosom Med 70:378-83. 2008..To explore prevalence and patterns of suicidal attempts in persons with anorexia nervosa (AN)... - Smoking in eating disordersDoris Anzengruber
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7160, USA
Eat Behav 7:291-9. 2006..Given the high prevalence, the impact of ongoing smoking on maintenance of eating disorders symptoms is worthy of both clinical and research attention... - Features associated with excessive exercise in women with eating disordersHemal Shroff
Department of Psychiatry, University of North Carolina, Chapel Hill, NC 27599-7160, and Center for Eating Disorders at Sheppard and Enoch Pratt Hospital, Towson, MD, USA
Int J Eat Disord 39:454-61. 2006..CONCLUSION: Excessive exercise may be associated particularly with the purging subtype of AN as well as with a constellation of anxious/obsessional temperament and personality characteristics among women with eating disorders... - Temporal patterns of recovery across eating disorder subtypesAnn Von Holle
Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
Aust N Z J Psychiatry 42:108-17. 2008..To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN)... - Features associated with diet pill use in individuals with eating disordersLauren Reba-Harrelson
Department of Psychiatry, University of North Carolina at Chapel Hill, NC, United States
Eat Behav 9:73-81. 2008..In the eating disorder population, vigilant screening for diet pill use should be routine clinical practice... - Features associated with laxative abuse in individuals with eating disordersFederica Tozzi
Department of Psychiatry, University of North Carolina at Chapel Hill, 1st floor Neurosciences Hospital, CB #7160, Chapel Hill, North Carolina 27599-7160, USA
Psychosom Med 68:470-7. 2006..CONCLUSIONS: The function of laxative abuse may differ across individuals with eating disorders, alternatively serving as a method of purging and a form of self-harm... - Significant linkage on chromosome 10p in families with bulimia nervosaCynthia M Bulik
Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
Am J Hum Genet 72:200-7. 2003..92 and 3.39, meet the widely accepted criterion for genomewide significance. Another region on 14q meets the criterion for genomewide suggestive linkage, with MLSs of 1.97 (full sample) and 1.75 (subset) at 62 centimorgans from p-ter... - Homosexual mating preferences from an evolutionary perspective: sexual selection theory revisitedKyle L Gobrogge
Program in Neuroscience and Department of Psychology, Florida State University, Tallahassee, FL, USA
Arch Sex Behav 36:717-23. 2007..In addition, they highlight the importance of examining relationship type in evolutionary studies of mating preferences, as men's partner preferences show important differences depending upon the type of relationship sought...
Research Grants
- A twin study of ovarian hormones and disordered eatingKelly Klump; Fiscal Year: 2009..Greater insight into neurobiological mechanisms will narrow the search for candidate genes and contribute to improved treatment and prevention of these disorders. ..
- Familial Transmission of Eating Pathology & Sex HormonesKelly Klump; Fiscal Year: 2002..abstract_text> ..
- Genetic and Environmental Risk for Eating DisordersKelly Klump; Fiscal Year: 2003..Findings from this study will significantly increase understanding of developmental risk factors for eating disorders and potentially inform intervention and prevention efforts aimed at their amelioration. ..
- A twin study of ovarian hormones and disordered eatingKelly Klump; Fiscal Year: 2009..Greater insight into neurobiological mechanisms will narrow the search for candidate genes and contribute to improved treatment and prevention of these disorders. ..
- A twin study of ovarian hormones and disordered eatingKelly L Klump; Fiscal Year: 2010..Greater insight into neurobiological mechanisms will narrow the search for candidate genes and contribute to improved treatment and prevention of these disorders. ..
- The Effects of Estradiol on Genetic Risk for Disordered Eating During PubertyKelly L Klump; Fiscal Year: 2010..Greater insight into neurobiological factors that contribute to these genetic effects will narrow the search for candidate genes and ultimately contribute to improved treatment and prevention of these disorders. ..