Research Topics
Species | M KiupelSummaryAffiliation: Michigan State University Country: USA Publications
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Detail Information
Publications
Proposal of a 2-tier histologic grading system for canine cutaneous mast cell tumors to more accurately predict biological behaviorM Kiupel
Michigan State University, Department of Pathobiology and Diagnostic Investigation, Diagnostic Center for Population and Animal Health, 4125 Beaumont Road, Lansing, MI 48910, USA
Vet Pathol 48:147-55. 2011..The median survival time was less than 4 months for high-grade MCTs but more than 2 years for low-grade MCTs...
Mycoplasmosis in ferretsMatti Kiupel
Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI 48910, USA
Emerg Infect Dis 18:1763-70. 2012..molare and M. lagogenitalium. These findings indicate a causal association between the novel Mycoplasma species and the newly recognized pulmonary disease...
Defining the "core microbiome" of the microbial communities in the tonsils of healthy pigsBeth A Lowe
Department of Microbiology and Molecular Genetics and the Center for Microbial Pathogenesis, Michigan State University, East Lansing, MI, USA
BMC Microbiol 12:20. 2012....
Diagnostic sensitivity and specificity of in situ hybridization and immunohistochemistry for Eastern equine encephalitis virus and West Nile virus in formalin-fixed, paraffin-embedded brain tissue of horsesKate E Pennick
Diagnostic Center for Population and Animal Health, College of Veterinary Medicine, Michigan State University, Lansing, MI 48910, USA
J Vet Diagn Invest 24:333-8. 2012..Both IHC and ISH are highly specific and sensitive diagnostic methods to detect EEEV in equine FFPE brain tissues, although neither appear effective for the diagnosis of WNV in equine neurologic cases...
Evaluation of prognostic markers for canine mast cell tumors treated with vinblastine and prednisoneJoshua D Webster
Comparative Medicine and Integrative Biology Program, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA
BMC Vet Res 4:32. 2008..Disease-free intervals (DFI) and overall survival times (OS) of dogs with similar pretreatment prognostic indices postoperatively treated with chemotherapy were compared to dogs treated with surgery alone...
Sensitivity and specificity of monoclonal and polyclonal immunohistochemical staining for West Nile virus in various organs from American crows (Corvus brachyrhynchos)Rebecca C Smedley
Diagnostic Center for Population and Animal Health and Department of Pathobiology and Diagnostic Investigation, MI, USA
BMC Infect Dis 7:49. 2007....
Evaluation of the kinase domain of c-KIT in canine cutaneous mast cell tumorsJoshua D Webster
Comparative Medicine and Integrative Biology Program, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA
BMC Cancer 6:85. 2006..However, some canine MCTs have aberrant KIT localization but lack ITD c-KIT mutations, suggesting that other mutations or other factors may be responsible for aberrant KIT localization in these tumors...
Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11Emmalena Gregory-Bryson
Comparative Medicine and Integrative Biology Program, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA
BMC Cancer 10:559. 2010....
West Nile virus infection in Eastern fox squirrels (Sciurus niger)M Kiupel
Diagnostic Center for Population and Animal Health, Michigan State University, G300 VMC, East Lansing, MI 48824, USA
Vet Pathol 40:703-7. 2003..The kidneys of all three squirrels stained positive with immunohistochemistry for WNV, whereas the brain and heart were positive in only one animal. Two of the three squirrels were positive for WNV by RT-PCR...
The use of KIT and tryptase expression patterns as prognostic tools for canine cutaneous mast cell tumorsJ D Webster
Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing 48824, USA
Vet Pathol 41:371-7. 2004..On the basis of these results, we propose a new prognostic classification of canine cutaneous MCTs, according to their KIT-staining pattern, that can be used for the routine prognostic evaluation of canine cutaneous MCTs...
Impact of tumour depth, tumour location and multiple synchronous masses on the prognosis of canine cutaneous mast cell tumoursM Kiupel
Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI 48910, USA
J Vet Med A Physiol Pathol Clin Med 52:280-6. 2005..However, these findings were not confirmed by multivariable analysis. Tumour depth was of no prognostic significance for dogs with cutaneous MCTs...
Diagnostic algorithm to differentiate lymphoma from inflammation in feline small intestinal biopsy samplesM Kiupel
Department of Pathobiology and Diagnostic Investigation, Diagnostic Center for Population and Animal Health, Michigan State University, 4125 Beaumont Road, Lansing, MI 48910, USA
Vet Pathol 48:212-22. 2011....
Nested case-control study of feline calicivirus viruria, oral carriage, and serum neutralizing antibodies in cats with idiopathic cystitisJ Larson
Department of Small Animal Clinical SciencesCollege of Veterinary Medicine, Michigan State University Veterinary Teaching Hospital, East Lansing, MI, USA
J Vet Intern Med 25:199-205. 2011..The epidemiology of feline calicivirus (FCV) infection in cats with idiopathic cystitis (FIC) has not been investigated by contemporary molecular biologic methods...
Cellular proliferation in canine cutaneous mast cell tumors: associations with c-KIT and its role in prognosticationJ D Webster
Comparative Medicine and Integrative Biology Program, Michigan State University, Lansing, MI 48910, USA
Vet Pathol 44:298-308. 2007....
Clinical and pathologic features of West Nile virus infection in native North American owls (Family strigidae)S D Fitzgerald
Diagnostic Center for Population and Animal Health and Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
Avian Dis 47:602-10. 2003..This report is the first detailed description of the pathology of West Nile virus infection in Strigiformes and indicates that this bird family is susceptible to natural infection with West Nile virus...
Expression of the embryonic transcription factor Oct4 in canine neoplasms: a potential marker for stem cell subpopulations in neoplasiaJ D Webster
Comparative Medicine and Integrative Biology Program, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA
Vet Pathol 44:893-900. 2007....
Immunohistochemical detection of retinoid receptors in tumors from 30 dogs diagnosed with cutaneous lymphomaC H de Mello Souza
College of Veterinary Medicine, Veterinary Medical Teaching Hospital, University of Missouri Columbia, Columbia, MO, USA
J Vet Intern Med 24:1112-7. 2010..The expression of subtypes varies depending on the disease process. This study intended to detect the pattern of retinoid receptor expression in cutaneous lymphomas in dogs...
Detection of group C rotavirus in juvenile ferrets (Mustela putorius furo) with diarrhea by reverse transcription polymerase chain reaction: sequencing and analysis of the complete coding region of the VP6 geneA G Wise
Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI 48910, USA
Vet Pathol 46:985-91. 2009..Ferret Rota C-MSU virus was found to be most closely related to Shintoku group C rotavirus. This is the first definitive identification of a group C rotavirus in ferrets, based upon RT-PCR, sequencing, and genetic analysis...
Outbreak of neonatal diarrhea in farmed mink kits (Mustella vison) associated with enterotoxigenic Staphylococcus delphiniD G Sledge
PhD, DACVP, 152 A Diagnostic Center for Population and Animal Health, 4125 Beaumont Road, Lansing, MI 48910 8107, USA
Vet Pathol 47:751-7. 2010....
Recommended guidelines for the conduct and evaluation of prognostic studies in veterinary oncologyJ D Webster
Molecular Pathology Unit, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Vet Pathol 48:7-18. 2011..As mentioned, these guidelines were developed through an initiative of the American College of Veterinary Pathologists' Oncology Committee, and they have been reviewed and endorsed by the World Small Animal Veterinary Association...
Prognostic markers for canine melanocytic neoplasms: a comparative review of the literature and goals for future investigationR C Smedley
Diagnostic Center for Population and Animal Health, Michigan State University, East Lansing, Michigan, USA
Vet Pathol 48:54-72. 2011..This article represents an initiative of the American College of Veterinary Pathologists' Oncology Committee and has been reviewed and endorsed by the World Small Animal Veterinary Association...
Immunohistochemical diagnosis of canine oral amelanotic melanocytic neoplasmsR C Smedley
Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, Michigan, USA
Vet Pathol 48:32-40. 2011..The likelihood of correctly diagnosing canine oral amelanotic melanocytic neoplasms was dramatically higher when biopsy samples contained ample overlying and adjacent epithelium...
Malignant lymphoma in african lions (panthera leo)T M Harrison
4125 Beaumont Road 152A, Lansing, MI, USA
Vet Pathol 47:952-7. 2010..Neither FeLV nor FIV, important causes of malignant lymphoma in domestic cats, seems to be significant in the pathogenesis of malignant lymphoma in African lions...
Somatotroph pituitary tumors in budgerigars (Melopsittacus undulatus)I M Langohr
Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
Vet Pathol 49:503-7. 2012..The common occurrence and early onset may suggest a genetic predisposition of budgerigars to develop somatotroph pituitary tumors with a high incidence of local invasion and with metastatic potential...
Peliod hepatocellular carcinoma in a domesticated ferret (Mustela putorius furo)Y Jones
Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, USA
J Vet Diagn Invest 18:228-31. 2006..Bilateral, adrenocortical hyperplasia also was evident. Speculation about a possible association between the variant of hepatocellular neoplasia diagnosed in this animal and its adrenal pathologic changes was done...
Multipotential osteosarcoma with various mesenchymal differentiations in a young dogM J Hoenerhoff
Department of Pathobiology and Diagnostic Investigation, Diagnostic Center for Population and Animal Health, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48823, USA
Vet Pathol 41:264-8. 2004..In addition, the wide range of mesenchymal tissue differentiation of this neoplasm was unusual, and to the authors' knowledge, an osteosarcoma with this degree of multiple differentiation has not been previously reported in the dog...
Multicentric squamous cell carcinoma in situ associated with papillomavirus in a ferretA Rodrigues
Texas A and M University, VTPB MS 4467, College of Veterinary Medicine, College Station, TX 77845 4467, USA
Vet Pathol 47:964-8. 2010..To the authors' knowledge, this is the first report of a ferret multicentric squamous cell carcinoma in situ associated with papillomavirus...
Cutaneous lymphomas in European pet rabbits (Oryctolagus cuniculus)J M Ritter
Diagnostic Center for Population and Animal Health and Department of Pathobiology and Diagnostic Investigation, Michigan State University, 4125 Beaumont Road, Lansing, MI 48910, USA
Vet Pathol 49:846-51. 2012..Further investigation into genetic and extrinsic factors associated with the development of these tumors is warranted...
Fatal herpesvirus encephalitis in a reticulated giraffe (Giraffa camelopardalis reticulata)M J Hoenerhoff
Diagnostic Center for Population and Animal Health, Michigan State University, 4125 Beaumont Road, Lansing, MI 49170, USA
Vet Pathol 43:769-72. 2006..This raises concerns for cross-species transmission of EHV-1 when housing equids together with other species in zoologic collections...
Gastric neuroendocrine carcinomas in bearded dragons (Pogona vitticeps)J M Ritter
Diagnostic Center for Population and Animal Health, Department of Pathobiology and Diagnostic Investigation, Michigan State University, Lansing, MI 48910, USA
Vet Pathol 46:1109-16. 2009....
Concurrent gastrinoma and somatostatinoma in a 10-year-old Portuguese water dogM Hoenerhoff
Department of Pathobiology and Diagnostic Investigations, Diagnostic Center for Population and Animal Health, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48823, USA
J Comp Pathol 130:313-8. 2004..Immunohistochemistry is necessary to confirm the diagnosis of a pancreatic islet cell gastrinoma...
An outbreak of fowl cholera in ring-necked pheasants (Phasianus colchicus)P Einum
College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
Avian Dis 47:777-80. 2003..Pasteurlla multocida serotype 3/4 was isolated from liver and spleen. In this paper, we report an outbreak of acute fowl cholera in ring-necked pheasants...
Choroid plexus papilloma in a Scottish highland cowM J Hoenerhoff
Diagnostic Center for Population and Animal Health, Department of Pathobiology and Diagnostic Investigation, Michigan State University College of Veterinary Medicine, Lansing, MI 48910, USA
J Comp Pathol 135:146-9. 2006..Neither cilia nor basal bodies were identified. The gross, microscopical, immunohistochemical and ultrastructural findings were consistent with those of a choroid plexus papilloma...
Classification of canine urinary bladder urothelial tumours based on the World Health Organization/International Society of Urological Pathology consensus classificationD J Patrick
MPI Research, Mattawan, Michigan 49071, USA
J Comp Pathol 135:190-9. 2006..This paper presents the salient features of the new WHO and ISUP consensus classification and provides illustrations of the various tumour types that were directly applicable to the dog...
Transcription factor GATA-4 is a marker of anaplasia in adrenocortical neoplasms of the domestic ferret (Mustela putorius furo)R A Peterson
Department of Pediatrics, Box 8208, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA
Vet Pathol 41:446-9. 2004..We conclude that GATA-4 can function as a marker of anaplasia in ferret adrenocortical tumors...
Uveal spindle cell tumor of blue-eyed dogs: an immunohistochemical studyM K Zarfoss
Department of Pathobiological Sciences, University of Wisconsin Madison, Madison, WI 53706, USA
Vet Pathol 44:276-84. 2007..The relationship between spindle cell tumors of the anterior uvea of dogs, altered neural crest, blue iris color, and ultraviolet radiation has not yet been fully elucidated...
Primary hyperaldosteronism in a dog with concurrent lymphomaK D Johnson
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO, USA
J Vet Med A Physiol Pathol Clin Med 53:467-70. 2006..Hyperaldosteronism is a rarely reported endocrinopathy in the dog. This report describes a case in which immunohistochemistry was utilized to confirm the diagnosis of an aldosterone-secreting tumour...
Clinicopathologic features of a systemic coronavirus-associated disease resembling feline infectious peritonitis in the domestic ferret (Mustela putorius)M M Garner
Northwest ZooPath, 654 W Main, Monroe, WA 98296, USA
Vet Pathol 45:236-46. 2008..Partial sequencing of the coronavirus spike gene obtained from frozen tissue indicates that the virus is related to ferret enteric coronavirus...
Hyalinizing pancreatic adenocarcinoma in six dogsM M Dennis
Veterinary Diagnostic Laboratory, Animal Population Health Institute, Colorado State University, Fort Collins, CO, USA
Vet Pathol 45:475-83. 2008..Studies that associate exocrine pancreatic carcinoma grade and histologic subtype with prognostic outcomes in the dog are warranted such that appropriate therapy can be elected...
