Gregg Howe

Summary

Affiliation: Michigan State University
Country: USA

Publications

  1. pmc Cytochrome P450-dependent metabolism of oxylipins in tomato. Cloning and expression of allene oxide synthase and fatty acid hydroperoxide lyase
    G A Howe
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing 48824, USA
    Plant Physiol 123:711-24. 2000
  2. ncbi request reprint Plant immunity to insect herbivores
    Gregg A Howe
    Department of Energy Plant Research Laboratory and Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Annu Rev Plant Biol 59:41-66. 2008
  3. ncbi request reprint Oxylipin metabolism in response to stress
    Gregg A Howe
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Curr Opin Plant Biol 5:230-6. 2002
  4. pmc The tomato suppressor of prosystemin-mediated responses2 gene encodes a fatty acid desaturase required for the biosynthesis of jasmonic acid and the production of a systemic wound signal for defense gene expression
    Chuanyou Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 15:1646-61. 2003
  5. pmc Resistance of cultivated tomato to cell content-feeding herbivores is regulated by the octadecanoid-signaling pathway
    Chuanyou Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 130:494-503. 2002
  6. pmc Jasmonate-inducible plant enzymes degrade essential amino acids in the herbivore midgut
    Hui Chen
    Department of Energy Plant Research Laboratory, Michigan Proteome Consortium, Michigan State University, East Lansing, MI 48824, USA
    Proc Natl Acad Sci U S A 102:19237-42. 2005
  7. pmc A critical role of two positively charged amino acids in the Jas motif of Arabidopsis JAZ proteins in mediating coronatine- and jasmonoyl isoleucine-dependent interactions with the COI1 F-box protein
    Maeli Melotto
    Department of Energy, Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Plant J 55:979-88. 2008
  8. pmc Top hits in contemporary JAZ: an update on jasmonate signaling
    Hoo Sun Chung
    DOE Plant Research Laboratory, Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 1312, USA
    Phytochemistry 70:1547-59. 2009
  9. pmc Functional diversification of acyl-coenzyme A oxidases in jasmonic acid biosynthesis and action
    Anthony L Schilmiller
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 143:812-24. 2007
  10. ncbi request reprint Identification of a peroxisomal acyl-activating enzyme involved in the biosynthesis of jasmonic acid in Arabidopsis
    Abraham J K Koo
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    J Biol Chem 281:33511-20. 2006

Research Grants

  1. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg A Howe; Fiscal Year: 2010
  2. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg Howe; Fiscal Year: 2009
  3. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg Howe; Fiscal Year: 2007
  4. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg Howe; Fiscal Year: 2002
  5. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg A Howe; Fiscal Year: 2010

Collaborators

Detail Information

Publications35

  1. pmc Cytochrome P450-dependent metabolism of oxylipins in tomato. Cloning and expression of allene oxide synthase and fatty acid hydroperoxide lyase
    G A Howe
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing 48824, USA
    Plant Physiol 123:711-24. 2000
    ..These results demonstrate that tomato uses genetically distinct signaling pathways for the regulation of different classes of wound responsive genes...
  2. ncbi request reprint Plant immunity to insect herbivores
    Gregg A Howe
    Department of Energy Plant Research Laboratory and Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Annu Rev Plant Biol 59:41-66. 2008
    ....
  3. ncbi request reprint Oxylipin metabolism in response to stress
    Gregg A Howe
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Curr Opin Plant Biol 5:230-6. 2002
    ..Increasing evidence indicates that the collective biological importance of oxylipins in plants is comparable to that of the eicosanoid family of lipid mediators in animals...
  4. pmc The tomato suppressor of prosystemin-mediated responses2 gene encodes a fatty acid desaturase required for the biosynthesis of jasmonic acid and the production of a systemic wound signal for defense gene expression
    Chuanyou Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 15:1646-61. 2003
    ....
  5. pmc Resistance of cultivated tomato to cell content-feeding herbivores is regulated by the octadecanoid-signaling pathway
    Chuanyou Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 130:494-503. 2002
    ..Tight linkage of Def-1 to a T-DNA insertion harboring the maize (Zea mays) Dissociation transposable element suggests a strategy for directed transposon tagging of the gene...
  6. pmc Jasmonate-inducible plant enzymes degrade essential amino acids in the herbivore midgut
    Hui Chen
    Department of Energy Plant Research Laboratory, Michigan Proteome Consortium, Michigan State University, East Lansing, MI 48824, USA
    Proc Natl Acad Sci U S A 102:19237-42. 2005
    ....
  7. pmc A critical role of two positively charged amino acids in the Jas motif of Arabidopsis JAZ proteins in mediating coronatine- and jasmonoyl isoleucine-dependent interactions with the COI1 F-box protein
    Maeli Melotto
    Department of Energy, Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Plant J 55:979-88. 2008
    ....
  8. pmc Top hits in contemporary JAZ: an update on jasmonate signaling
    Hoo Sun Chung
    DOE Plant Research Laboratory, Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 1312, USA
    Phytochemistry 70:1547-59. 2009
    ..Functional diversification of JAZ proteins by alternative splicing, together with the ability of JAZ proteins to homo- and heterodimerize, provide mechanisms to enhance combinatorial diversity and versatility in gene regulation by JA...
  9. pmc Functional diversification of acyl-coenzyme A oxidases in jasmonic acid biosynthesis and action
    Anthony L Schilmiller
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 143:812-24. 2007
    ..brassicicola challenge. Thus, different types of biotic stress may induce JA synthesis via distinct enzymatic routes...
  10. ncbi request reprint Identification of a peroxisomal acyl-activating enzyme involved in the biosynthesis of jasmonic acid in Arabidopsis
    Abraham J K Koo
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    J Biol Chem 281:33511-20. 2006
    ..The results also demonstrate the utility of co-expression analysis for identification of factors that contribute to jasmonate homeostasis...
  11. ncbi request reprint Systemic signaling in the wound response
    Anthony L Schilmiller
    Department of Energy Plant Research Laboratory and Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA
    Curr Opin Plant Biol 8:369-77. 2005
    ..Recent studies in tomato suggest that the peptide signal systemin promotes long-distance defense responses by amplifying jasmonate production in vascular tissues...
  12. pmc Role of beta-oxidation in jasmonate biosynthesis and systemic wound signaling in tomato
    Chuanyou Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 17:971-86. 2005
    ..These findings support a role for peroxisomes in the production of lipid-based signaling molecules that promote systemic defense responses...
  13. ncbi request reprint Regulation of plant arginase by wounding, jasmonate, and the phytotoxin coronatine
    Hui Chen
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    J Biol Chem 279:45998-6007. 2004
    ..These results highlight striking similarities in the regulation of arginase in plants and animals and suggest that stress-induced arginase may perform similar roles in diverse biological systems...
  14. pmc The tomato homolog of CORONATINE-INSENSITIVE1 is required for the maternal control of seed maturation, jasmonate-signaled defense responses, and glandular trichome development
    Lei Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 16:126-43. 2004
    ..These findings indicate that the JA/COI1 signaling pathway regulates distinct developmental processes in different plants and suggest a role for JA in the promotion of glandular trichome-based defenses...
  15. ncbi request reprint Identification of a jasmonate-regulated allene oxide synthase that metabolizes 9-hydroperoxides of linoleic and linolenic acids
    Aya Itoh
    Department of Energy Plant Research Laboratory and Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824 1312, USA
    J Biol Chem 277:46051-8. 2002
    ..These findings suggest that LeAOS3 plays a role in the metabolism of 9-lipoxygenase-derived hydroperoxides in roots, and that this branch of oxylipin biosynthesis is regulated by the jasmonate signaling cascade...
  16. ncbi request reprint Virulence systems of Pseudomonas syringae pv. tomato promote bacterial speck disease in tomato by targeting the jasmonate signaling pathway
    Youfu Zhao
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Plant J 36:485-99. 2003
    ....
  17. ncbi request reprint The tomato mutant spr1 is defective in systemin perception and the production of a systemic wound signal for defense gene expression
    Gyu In Lee
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Plant J 33:567-76. 2003
    ..It was also demonstrated that spr1 plants are not affected in the local or systemic expression of a subset of rapidly induced wound-response genes, indicating the existence of a systemin-independent pathway for wound signaling...
  18. pmc COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine
    Leron Katsir
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Proc Natl Acad Sci U S A 105:7100-5. 2008
    ..These findings demonstrate that COI1 is a critical component of the JA receptor and that COR exerts its virulence effects by functioning as a potent agonist of this receptor system...
  19. pmc Jasmonate signaling: a conserved mechanism of hormone sensing
    Leron Katsir
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Curr Opin Plant Biol 11:428-35. 2008
    ....
  20. pmc A critical role for the TIFY motif in repression of jasmonate signaling by a stabilized splice variant of the JASMONATE ZIM-domain protein JAZ10 in Arabidopsis
    Hoo Sun Chung
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 21:131-45. 2009
    ..The ability of JAZ10.4 to interact with MYC2 is consistent with a model in which a JAZ10.4-containing protein complex directly represses the activity of transcription factors that promote expression of JA response genes...
  21. doi request reprint A rapid wound signal activates the systemic synthesis of bioactive jasmonates in Arabidopsis
    Abraham J K Koo
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant J 59:974-86. 2009
    ..These results are consistent with a model in which a rapidly transmitted wound signal triggers the systemic synthesis of JA, which, upon conversion to JA-Ile, activates the expression of early response genes by the SCF(COI1)/JAZ pathway...
  22. pmc The wound hormone jasmonate
    Abraham J K Koo
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, United States
    Phytochemistry 70:1571-80. 2009
    ..These results provide a framework for understanding how plants recognize and respond to tissue injury...
  23. pmc Distinct roles for jasmonate synthesis and action in the systemic wound response of tomato
    Lei Li
    Department of Energy Plant Research Laboratory and Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA
    Proc Natl Acad Sci U S A 99:6416-21. 2002
    ..These findings suggest that JA, or a related compound derived from the octadecanoid pathway, may act as a transmissible wound signal...
  24. pmc Regulation and function of Arabidopsis JASMONATE ZIM-domain genes in response to wounding and herbivory
    Hoo Sun Chung
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Plant Physiol 146:952-64. 2008
    ..Our results also indicate that the timing of JA-induced transcription in response to wounding is more rapid than previously realized...
  25. pmc Distortion of trichome morphology by the hairless mutation of tomato affects leaf surface chemistry
    Jin Ho Kang
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    J Exp Bot 61:1053-64. 2010
    ....
  26. ncbi request reprint Constitutive activation of the jasmonate signaling pathway enhances the production of secondary metabolites in tomato
    Hui Chen
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, 48824, USA
    FEBS Lett 580:2540-6. 2006
    ....
  27. ncbi request reprint Loss of function of COBRA, a determinant of oriented cell expansion, invokes cellular defence responses in Arabidopsis thaliana
    Jae Heung Ko
    Department of Forestry, Michigan State University, East Lansing, MI 48824, USA
    J Exp Bot 57:2923-36. 2006
    ..These results provide potential clues to the mechanisms by which plant cells initially perceive biotic stress at the cell surface...
  28. pmc Stability of plant defense proteins in the gut of insect herbivores
    Hui Chen
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 143:1954-67. 2007
    ..We conclude that proteomic analysis of frass from insect herbivores provides a robust experimental approach to identify hyperstable plant proteins that serve important roles in defense...
  29. pmc Tomato MAPKs LeMPK1, LeMPK2, and LeMPK3 function in the systemin-mediated defense response against herbivorous insects
    Pramod Kaitheri Kandoth
    Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA
    Proc Natl Acad Sci U S A 104:12205-10. 2007
    ..Here we show that cosilencing of MPK1 and MPK2 compromised prosystemin-mediated resistance to Manduca sexta (Lepidoptera) herbivory, demonstrating that MPK1 and MPK2 are also required for successful defenses against herbivorous insects...
  30. pmc New weapons and a rapid response against insect attack
    John Browse
    Institute of Biological Chemistry, Washington State University, Pullman, WA 99164 6340, USA
    Plant Physiol 146:832-8. 2008
  31. ncbi request reprint Characterization and cDNA-microarray expression analysis of 12-oxophytodienoate reductases reveals differential roles for octadecanoid biosynthesis in the local versus the systemic wound response
    Jochen Strassner
    Plant Biochemistry and Physiology Group, Institute of Plant Sciences, ETH Zurich, Universitatstrasse 2, CH 8092 Zurich, Switzerland
    Plant J 32:585-601. 2002
    ..The transcriptional activation of the octadecanoid pathway and the accumulation of JA to high levels are, thus not required for the activation of defense gene expression in systemic tissues...
  32. ncbi request reprint Obituary: Clarence A. "Bud" Ryan (1931-2007)
    Edward E Ted Farmer
    Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland
    Phytochemistry 69:1454-6. 2008
  33. ncbi request reprint Characterization of novel imidazole derivative, JM-8686, a potent inhibitor of allene oxide synthase
    Keimei Oh
    Department of Biotechnology, Faculty of Bio resource Sciences, Akita Prefectural University, Akita 010 0195, Japan
    FEBS Lett 580:5791-6. 2006
    ..6+/-0.2 microM, suggesting that JM-8686 binds to the prosthetic heme iron of AOS. Comparison of the inhibitory potency of the compound against HPL (CYP74B) from tomato revealed that JM-8686 was a highly selective inhibitor for AOS...
  34. ncbi request reprint JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling
    Bryan Thines
    Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 6340, USA
    Nature 448:661-5. 2007
    ....
  35. ncbi request reprint Structure determination and analysis of acyl-CoA oxidase (ACX1) from tomato
    Rachel A Powers
    Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA
    Acta Crystallogr D Biol Crystallogr 62:683-6. 2006
    ..Although the tertiary structure of LeACX1 is essentially similar to the previously determined structures of ACX enzymes, the packing within the unit cells is distinctly different...

Research Grants13

  1. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg A Howe; Fiscal Year: 2010
    ....
  2. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg Howe; Fiscal Year: 2009
    ....
  3. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg Howe; Fiscal Year: 2007
    ..abstract_text> ..
  4. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg Howe; Fiscal Year: 2002
    ....
  5. REGULATION OF DEFENSE SIGNALING IN TOMATO
    Gregg A Howe; Fiscal Year: 2010
    ....