Norman G Hord

Summary

Affiliation: Michigan State University
Country: USA

Publications

  1. ncbi Dietary nitrates, nitrites, and cardiovascular disease
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Curr Atheroscler Rep 13:484-92. 2011
  2. ncbi Eukaryotic-microbiota crosstalk: potential mechanisms for health benefits of prebiotics and probiotics
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan 48824, USA
    Annu Rev Nutr 28:215-31. 2008
  3. ncbi Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells
    Jenifer I Fenton
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Int J Cancer 122:2437-45. 2008
  4. ncbi Food sources of nitrates and nitrites: the physiologic context for potential health benefits
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Am J Clin Nutr 90:1-10. 2009
  5. ncbi Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activation
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute Bethesda, MD, USA
    Carcinogenesis 28:455-64. 2007
  6. ncbi Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7361, USA
    Carcinogenesis 27:1507-15. 2006
  7. ncbi Stage matters: choosing relevant model systems to address hypotheses in diet and cancer chemoprevention research
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7361, USA
    Carcinogenesis 27:893-902. 2006
  8. ncbi Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, National Cancer Institute, Division of Cancer Prevention, 6130 Executive Boulevard, MSC 7361, Bethesda, MD 20892 7361, USA
    Cancer Epidemiol Biomarkers Prev 14:1646-52. 2005
  9. ncbi Nitrate and nitrite content of human, formula, bovine, and soy milks: implications for dietary nitrite and nitrate recommendations
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Breastfeed Med 6:393-9. 2011
  10. ncbi Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype
    Jenifer I Fenton
    Department of Food Science and Human Nutrition, Michigan State University, 2110 Anthony Hall East Lansing, MI 48824, USA
    Carcinogenesis 23:1065-70. 2002

Research Grants

  1. Flavonoid Modulation of Epithelial Migration and Signal*
    NORMAN HORD; Fiscal Year: 2004

Collaborators

Detail Information

Publications15

  1. ncbi Dietary nitrates, nitrites, and cardiovascular disease
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Curr Atheroscler Rep 13:484-92. 2011
    ..This review includes a call for regulatory bodies to consider all available data on the beneficial physiologic roles of nitrate and nitrite in order to derive rational bases for dietary recommendations...
  2. ncbi Eukaryotic-microbiota crosstalk: potential mechanisms for health benefits of prebiotics and probiotics
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan 48824, USA
    Annu Rev Nutr 28:215-31. 2008
    ....
  3. ncbi Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells
    Jenifer I Fenton
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Int J Cancer 122:2437-45. 2008
    ..These data may have broad implications for diet and lifestyle strategies for the prevention and treatment of obesity-associated cancers...
  4. ncbi Food sources of nitrates and nitrites: the physiologic context for potential health benefits
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Am J Clin Nutr 90:1-10. 2009
    ..The strength of the evidence linking the consumption of nitrate- and nitrite-containing plant foods to beneficial health effects supports the consideration of these compounds as nutrients...
  5. ncbi Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activation
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute Bethesda, MD, USA
    Carcinogenesis 28:455-64. 2007
    ..These data provide a rational basis for leptin-induced cross-talk between preneoplastic epithelial cells and immune cells that may influence the promotional phase of carcinogenesis...
  6. ncbi Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7361, USA
    Carcinogenesis 27:1507-15. 2006
    ..The elucidation of the leptin-initiated mechanism of preneoplastic cell proliferation establishes a biologically plausible link between the adipocyte-specific cytokine leptin and obesity-associated colon cancer...
  7. ncbi Stage matters: choosing relevant model systems to address hypotheses in diet and cancer chemoprevention research
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7361, USA
    Carcinogenesis 27:893-902. 2006
    ..The utilization of cell culture systems modeling early, middle and late stages of tumorigenesis will yield important insights into mechanisms by which dietary components impact cancer progression...
  8. ncbi Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines
    Jenifer I Fenton
    Cancer Prevention Fellowship Program, National Cancer Institute, Division of Cancer Prevention, 6130 Executive Boulevard, MSC 7361, Bethesda, MD 20892 7361, USA
    Cancer Epidemiol Biomarkers Prev 14:1646-52. 2005
    ..These data provide the first evidence that leptin may interact with IGFs to promote survival and expansion of colonic epithelial cells that were Apc deficient (ApcMin/+) but not those expressing wild-type Apc (Apc+/+)...
  9. ncbi Nitrate and nitrite content of human, formula, bovine, and soy milks: implications for dietary nitrite and nitrate recommendations
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
    Breastfeed Med 6:393-9. 2011
    ..Human milk is known to confer significant nutritional and immunological benefits for the infant. Consumption of formula, cow's, and soy milk may be used as alternatives to human milk for infants...
  10. ncbi Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype
    Jenifer I Fenton
    Department of Food Science and Human Nutrition, Michigan State University, 2110 Anthony Hall East Lansing, MI 48824, USA
    Carcinogenesis 23:1065-70. 2002
    ..The data suggest a potential mechanism by which curcumin may induce cells heterozygous for Apc to overcome defective cell migration, a phenotype associated with cell differentiation and apoptosis...
  11. ncbi Context is everything: Mining the normal and preneoplastic microenvironment for insights into the diet and cancer risk conundrum
    Norman G Hord
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA
    Mol Nutr Food Res 51:100-6. 2007
    ....
  12. ncbi Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion
    Jenifer I Fenton
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan, USA
    Mol Carcinog 47:9-21. 2008
    ..These data establish a biologically plausible mechanistic link between the elevated levels of growth factors and the increased risk of colon cancer associated with obesity...
  13. ncbi The role of dietary factors in cancer prevention: beyond fruits and vegetables
    Mark T Williams
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan 48824, USA
    Nutr Clin Pract 20:451-9. 2005
    ..The preparation and enjoyment of meals in a convivial atmosphere is a vital component of lifestyles to prevent chronic diseases such as cancer and certain cardiovascular diseases...
  14. ncbi Flavonoids promote cell migration in nontumorigenic colon epithelial cells differing in Apc genotype: implications of matrix metalloproteinase activity
    Jenifer I Fenton
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA
    Nutr Cancer 48:182-8. 2004
    ..Induction of the migratory phenotype by flavonoids in these models of preneoplastic epithelial cells suggests a novel mechanism for colon cancer prevention...
  15. ncbi Nutritional "omics" technologies for elucidating the role(s) of bioactive food components in colon cancer prevention
    Cindy D Davis
    Nutritional Sciences Research Group, NCI National Institutes of Health, Rockville, MD 20892 7328, USA
    J Nutr 135:2694-7. 2005
    ....

Research Grants1

  1. Flavonoid Modulation of Epithelial Migration and Signal*
    NORMAN HORD; Fiscal Year: 2004
    ..Ultimately, this research will provide critical information necessary for specific and rational dietary recommendations to decrease colon cancer risk in humans. ..