Research Topics
Species | JENIFER IMIG FENTONSummaryAffiliation: Michigan State University Country: USA Publications
Research Grants
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Detail Information
Publications
DHA-enriched fish oil targets B cell lipid microdomains and enhances ex vivo and in vivo B cell functionEric A Gurzell
1 Michigan State University, 208B G M Trout Bldg, East Lansing, MI 48824 1224, USA
J Leukoc Biol 93:463-70. 2013..These results support the hypothesis and an emerging concept that fish oil enhances B cell function in vivo...
Curcumin and docosahexaenoic acid block insulin-induced colon carcinoma cell proliferationJenifer I Fenton
Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
Prostaglandins Leukot Essent Fatty Acids 88:219-26. 2013..Insulin stimulated MAPK and MEK phosphorylation was inhibited by DHA and curcumin in MC38 cancer cells. Here we show that curcumin and DHA can block insulin-induced colon cancer cell proliferation in vitro via a MEK mediated mechanism...
Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell linesJenifer I Fenton
Cancer Prevention Fellowship Program, National Cancer Institute, Division of Cancer Prevention, 6130 Executive Boulevard, MSC 7361, Bethesda, MD 20892 7361, USA
Cancer Epidemiol Biomarkers Prev 14:1646-52. 2005..These data provide the first evidence that leptin may interact with IGFs to promote survival and expansion of colonic epithelial cells that were Apc deficient (ApcMin/+) but not those expressing wild-type Apc (Apc+/+)...
Stage matters: choosing relevant model systems to address hypotheses in diet and cancer chemoprevention researchJenifer I Fenton
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7361, USA
Carcinogenesis 27:893-902. 2006..The utilization of cell culture systems modeling early, middle and late stages of tumorigenesis will yield important insights into mechanisms by which dietary components impact cancer progression...
Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell lineJenifer I Fenton
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7361, USA
Carcinogenesis 27:1507-15. 2006..The elucidation of the leptin-initiated mechanism of preneoplastic cell proliferation establishes a biologically plausible link between the adipocyte-specific cytokine leptin and obesity-associated colon cancer...
Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activationJenifer I Fenton
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute Bethesda, MD, USA
Carcinogenesis 28:455-64. 2007..These data provide a rational basis for leptin-induced cross-talk between preneoplastic epithelial cells and immune cells that may influence the promotional phase of carcinogenesis...
Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cellsJenifer I Fenton
Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA
Int J Cancer 122:2437-45. 2008..These data may have broad implications for diet and lifestyle strategies for the prevention and treatment of obesity-associated cancers...
Diet-induced adiposity alters the serum profile of inflammation in C57BL/6N mice as measured by antibody arrayJ I Fenton
Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA
Diabetes Obes Metab 11:343-54. 2009..The demonstration of differential adipokine, cytokine and chemokine protein profile in control, lean and DIO mice may have implications for immune responsiveness and risk of disease...
Got black swimming dots in your cell culture? Identification of Achromobacter as a novel cell culture contaminantJennifer Sue Gray
Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA
Biologicals 38:273-7. 2010..The contaminating Achromobacter was eventually eliminated, without permanently harming the eukaryotic cells, using a combination of the antibiotics ciprofloxacin and piperacillin...
Research Grants
- role of adipokines in colon epithelial cell homeostasisJENIFER FENTON; Fiscal Year: 2007....
