Alison K Bauer

Summary

Affiliation: Michigan State University
Country: USA

Publications

  1. doi Review paper: the role of inflammation in mouse pulmonary neoplasia
    A K Bauer
    Department of Pathobiology and Diagnostic Investigation, Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824 USA
    Vet Pathol 46:369-90. 2009
  2. pmc Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, USA
    Mol Cancer 8:107. 2009
  3. pmc Identification of novel susceptibility genes in ozone-induced inflammation in mice
    A K Bauer
    Dept of Pathobiology and Diagnostic Investigation Center for Integrative Toxicology B43 Food Safety and Toxicology Bldg, Michigan State University, East Lansing, MI 48824, USA
    Eur Respir J 36:428-37. 2010
  4. pmc Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America
    PLoS ONE 6:e26590. 2011
  5. pmc Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Environ Health Perspect 119:1091-7. 2011
  6. pmc Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner
    Elizabeth A Rondini
    Department of Pathobiology and Diagnostic Investigation and Center for Integrative Toxicology, Michigan State University, East Lansing, MI, 48824, USA
    Part Fibre Toxicol 7:9. 2010
  7. doi Genetic mechanisms of susceptibility to ozone-induced lung disease
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Ann N Y Acad Sci 1203:113-9. 2010

Detail Information

Publications7

  1. doi Review paper: the role of inflammation in mouse pulmonary neoplasia
    A K Bauer
    Department of Pathobiology and Diagnostic Investigation, Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824 USA
    Vet Pathol 46:369-90. 2009
    ..Identification of molecular mechanisms that govern the association between inflammation and pulmonary neoplasia could provide novel preventive, diagnostic, and therapeutic strategies for a disease in which few biomarkers currently exist...
  2. pmc Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, USA
    Mol Cancer 8:107. 2009
    ..This study was designed to identify TLR4-mediated gene expression pathways that may be used as prognostic indicators of susceptibility to lung tumorigenesis in mice and provide insight into the mechanism...
  3. pmc Identification of novel susceptibility genes in ozone-induced inflammation in mice
    A K Bauer
    Dept of Pathobiology and Diagnostic Investigation Center for Integrative Toxicology B43 Food Safety and Toxicology Bldg, Michigan State University, East Lansing, MI 48824, USA
    Eur Respir J 36:428-37. 2010
    ..This integrative genetic analysis of Inf2 led to identification of novel O(3) susceptibility genes that may provide important, new therapeutic targets in susceptible individuals...
  4. pmc Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America
    PLoS ONE 6:e26590. 2011
    ..Our results were consistent with the concept that Nrf2 over-activation is an adaptive response of cancer conferring resistance to anti-cancer drugs and promoting malignancy...
  5. pmc Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Environ Health Perspect 119:1091-7. 2011
    ..Toll-like receptor 4 (TLR4) is involved in ozone (O3)-induced pulmonary hyperpermeability and inflammation, although the downstream signaling events are unknown...
  6. pmc Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner
    Elizabeth A Rondini
    Department of Pathobiology and Diagnostic Investigation and Center for Integrative Toxicology, Michigan State University, East Lansing, MI, 48824, USA
    Part Fibre Toxicol 7:9. 2010
    ....
  7. doi Genetic mechanisms of susceptibility to ozone-induced lung disease
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Ann N Y Acad Sci 1203:113-9. 2010
    ..Combined investigations across cell models, inbred mice, and humans have provided, and will continue to provide, important insight to understanding genetic factors that contribute to differential susceptibility to oxidants...

Research Grants2

  1. The role of toll-like receptor 4 in O3-induced lung inflammation and injury.
    Alison Bauer; Fiscal Year: 2007
    ..These novel pathways may provide preventive strategies for those individuals susceptible to O3. ..