Research Topics
Genomes and Genes
Species | Kathy J HelzlsouerSummaryAffiliation: Mercy Medical Center Country: USA Publications
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Detail Information
Publications
Dr. George W. Comstock--a primary care practitioner of public healthKathy J Helzlsouer
Prevention and Research Center, Mercy Medical Center, Baltimore, MD 21202, USA
Am J Epidemiol 168:816-8. 2008
Shedding light on serum vitamin d concentrations and the risk of rarer cancersKathy J Helzlsouer
The Prevention and Research Center, 227 St Paul Place, Baltimore, Maryland 21202, USA
Anticancer Agents Med Chem 13:65-9. 2013..Additionally, controversy persists concerning a potential increased risk of pancreatic cancer associated with serum 25OHD levels > 100 nmol/L due to conflicting results reported by two large prospective pooling projects...
C-reactive protein levels and subsequent cancer outcomes: results from a prospective cohort studyKathy J Helzlsouer
Prevention and Research Center, Mercy Medical Center, 6th Floor, 227 St Paul Place, Baltimore, MD 21202, USA
Eur J Cancer 42:704-7. 2006..However, the potential benefits of anti-inflammatory chemopreventive agents must be weighed against their adverse effects before widespread use is recommended...
The ongoing legacy--the George W. Comstock Center for Public Health Research and PreventionKathy J Helzlsouer
Prevention and Research Center, Mercy Medical Center, Baltimore, MD 21202, USA
Am J Epidemiol 168:673-5. 2008
Overview of the Cohort Consortium Vitamin D Pooling Project of Rarer CancersKathy J Helzlsouer
Mercy Medical Center, Baltimore, MD 21202, USA
Am J Epidemiol 172:4-9. 2010..The results of this study have application for the planning and conduct of intervention trials, especially in determining potential risks...
A prospective study of aromatase inhibitor therapy, vitamin D, C-reactive protein and musculoskeletal symptomsKathy J Helzlsouer
The Prevention and Research Center, The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 St Paul Place, 6th Floor, Baltimore, MD 21202, USA
Breast Cancer Res Treat 131:277-85. 2012..AI-associated symptoms were not associated with 25(OH)D or CRP concentrations...
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancerKonstantinos K Tsilidis
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
Cancer Causes Control 20:1739-51. 2009..Odds ratios (OR) and 95% confidence intervals (95% CI) were estimated using conditional logistic regression...
Circulating 25-hydroxyvitamin D and the risk of rarer cancers: Design and methods of the Cohort Consortium Vitamin D Pooling Project of Rarer CancersLisa Gallicchio
Mercy Medical Center, Baltimore, Maryland 21202, USA
Am J Epidemiol 172:10-20. 2010..This consortium approach permits estimation of the association between 25(OH)D and several rarer cancers with high accuracy and precision across a wide range of 25(OH)D concentrations...
Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort studyLisa Gallicchio
The Prevention and Research Center, The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, Baltimore, Maryland 21202, USA
BMC Med Genet 10:103. 2009..We also examined the associations between the SNPs and body mass index (BMI) and change in BMI over time...
Single nucleotide polymorphisms in inflammation-related genes and mortality in a community-based cohort in Washington County, MarylandLisa Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine, Mercy Medical Center, Baltimore, MD 21202, USA
Am J Epidemiol 167:807-13. 2008..The authors' findings from this community-based prospective cohort study suggest that the selected SNPs are not associated with overall or cause-specific death, although CRP genotypes may be associated with systemic inflammation...
Body mass, polymorphisms in obesity-related genes, and the risk of developing breast cancer among women with benign breast diseaseLisa Gallicchio
Prevention and Research Center, The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 St Paul Place, Baltimore, MD 21202, USA
Cancer Detect Prev 31:95-101. 2007....
Active cigarette smoking, household passive smoke exposure, and the risk of developing pancreatic cancerLisa Gallicchio
Department of Epidemiology, Room E6132, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA
Prev Med 42:200-5. 2006..Our results also indicate that household passive smoke exposure is not associated with pancreatic cancer risk, although our risk estimates lacked precision...
Prediagnostic circulating follicle stimulating hormone concentrations and ovarian cancer riskMeghan A McSorley
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Int J Cancer 125:674-9. 2009..These findings contradict the hypothesized role of FSH as a risk factor in ovarian carcinogenesis...
A prospective cohort study of bladder cancer risk in relation to active cigarette smoking and household exposure to secondhand cigarette smokeAnthony J Alberg
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Am J Epidemiol 165:660-6. 2007..9, 95% CL: 0.4, 2.3). This study further solidifies the evidence that active smoking is causally associated with bladder cancer. Additional studies are needed to determine whether passive smoking is a risk factor for bladder cancer...
Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE IIMing Hsi Wang
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Prostate 69:874-85. 2009..Chronic intra-prostatic inflammation and obesity are thought to influence prostate carcinogenesis. Thus, variants in genes in these pathways could be associated with prostate cancer risk...
Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based populationHan Yao Huang
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
BMC Genet 8:7. 2007..The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF...
N-acetyltransferase 2 (NAT2) genotypes, cigarette smoking, and the risk of breast cancerAnthony J Alberg
Department of Epidemiology, Room E6132B, The Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Cancer Detect Prev 28:187-93. 2004..The results for smoking were consistent with an inactivation role for NAT2 in breast cancer...
Metabolic syndrome components and colorectal adenoma in the CLUE II cohortKonstantinos K Tsilidis
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Cancer Causes Control 21:1-10. 2010..Thus, we evaluated the association between markers of the metabolic syndrome with colorectal adenoma development in a nested case-control study...
A prospective study of the associations between treated diabetes and cancer outcomesHsin Chieh Yeh
Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Diabetes Care 35:113-8. 2012....
Flame-broiled food, NAT2 acetylator phenotype, and breast cancer risk among women with benign breast diseaseLisa Gallicchio
Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21202, USA
Breast Cancer Res Treat 99:229-33. 2006..The variation of the association by acetylation phenotype, as determined by the genotypes of selected N-acetyltransferase 2 (NAT2) enzymes, was also examined...
Mismatch repair polymorphisms and the risk of colorectal cancerSonja I Berndt
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Int J Cancer 120:1548-54. 2007..No association was observed with the MSH6 and MLH1 polymorphisms overall. This study suggests that common polymorphisms in the mismatch repair gene, MSH3, may increase the risk of colorectal cancer, especially proximal colon cancer...
C-reactive protein concentrations and subsequent ovarian cancer riskMeghan A McSorley
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21202, USA, and Academic Oncology Unit, Guy s Hospital, London, United Kingdom
Obstet Gynecol 109:933-41. 2007..To estimate the association between prediagnostic levels of C-reactive protein (CRP), a marker of chronic systemic inflammation, and subsequent development of ovarian cancer...
Genetic variation in the nucleotide excision repair pathway and colorectal cancer riskSonja I Berndt
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Cancer Epidemiol Biomarkers Prev 15:2263-9. 2006..00003). Our study suggests that genetic polymorphisms in the NER genes, ERCC6 and XPC, may be associated with an increased risk of colorectal cancer...
No association between pre-diagnostic plasma C-reactive protein concentration and subsequent prostate cancerElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Prostate 59:393-400. 2004..We evaluated the association of pre-diagnostic plasma concentration of C-reactive protein, a sensitive, but non-specific indicator of inflammation, with subsequent risk of prostate cancer...
C-reactive protein and colorectal adenoma in the CLUE II cohortKonstantinos K Tsilidis
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Cancer Causes Control 19:559-67. 2008..Thus, we evaluated the association between plasma C-reactive protein concentration and development of colorectal adenoma in a nested case-control study...
Polymorphisms in estrogen-metabolizing and estrogen receptor genes and the risk of developing breast cancer among a cohort of women with benign breast diseaseLisa Gallicchio
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
BMC Cancer 6:173. 2006....
Alcohol dehydrogenase genetic polymorphisms, low-to-moderate alcohol consumption, and risk of breast cancerKala Visvanathan
Department of Epidemiology, The Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Alcohol Clin Exp Res 31:467-76. 2007..Because alcohol is a known risk factor for breast cancer, we evaluated the joint association of genetic variants in ADH and alcohol consumption in relation to breast cancer...
C-reactive protein and colorectal cancer risk: a systematic review of prospective studiesKonstantinos K Tsilidis
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Int J Cancer 123:1133-40. 2008..More work is needed to understand the extent to which circulating high-sensitivity C-reactive protein or other blood inflammatory markers are related to colonic inflammation...
Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancerHan Yao Huang
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 2223, USA
Am J Epidemiol 157:335-44. 2003..Findings do not replicate previous reports of a protective association between lycopene and prostate cancer, but they suggest potential chemopreventive effects of gamma-tocopherol on prostate cancer...
Cruciferous vegetable intake and lung cancer risk: a nested case-control study matched on cigarette smokingTram Kim Lam
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:2534-40. 2010..Cruciferous vegetables may reduce lung cancer risk. The association between intake of cruciferous vegetables and lung cancer risk was investigated in the CLUE II study, a community-based cohort established in 1989...
Fruit, vegetable, and antioxidant intake and all-cause, cancer, and cardiovascular disease mortality in a community-dwelling population in Washington County, MarylandJeanine M Genkinger
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Am J Epidemiol 160:1223-33. 2004..These findings support the general health recommendation to consume multiple servings of fruits and vegetables (5-9/day)...
Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratoriesDana E M Rollison
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Int J Cancer 113:769-74. 2005..Results for masked quality control tissues were concordant between laboratories. Nucleotide sequences for JCV, BKV and SV40 are rarely present in a large series of adult and pediatric brain tumors...
Circulating 25-hydroxyvitamin D and risk of kidney cancer: Cohort Consortium Vitamin D Pooling Project of Rarer CancersLisa Gallicchio
Mercy Medical Center, Baltimore, Maryland 21202, USA
Am J Epidemiol 172:47-57. 2010..The findings from this consortium-based study do not support the hypothesis that vitamin D is inversely associated with the risk of kidney cancer overall or with renal cell carcinoma specifically...
Smoking and risk of fatal prostate cancer in a prospective U.S. studySabine Rohrmann
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Urology 69:721-5. 2007..To examine the association of cigarette smoking with subsequent fatal prostate cancer...
Association between C-peptide concentration and prostate cancer incidence in the CLUE II cohort studyGabriel Y Lai
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Cancer Prev Res (Phila) 3:1334-41. 2010..However, we cannot rule out detection bias that might result if men with higher C-peptide have lower prostate-specific antigen irrespective of whether prostate cancer is present or not...
Non-cancer adverse health conditions and perceived health and function among cancer survivors participating in a community-based cohort study in Washington County, MarylandLisa Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 St Paul Place, Baltimore, MD 21202, USA
J Cancer Surviv 2:12-9. 2008....
Changes in bone biomarker concentrations and musculoskeletal symptoms among breast cancer patients initiating aromatase inhibitor therapy and women without a history of cancerLisa Gallicchio
The Prevention and Research Center The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, Baltimore, MD 21202, USA
J Bone Miner Res 27:1959-66. 2012..Breast cancer patients initiating AI therapy should be assessed and monitored for fracture risk using known clinical risk factors, including bone density, and managed appropriately...
Association of vasectomy and prostate cancer among men in a Maryland cohortSabine Rohrmann
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, 615 N. Wolfe St, Room E6138, Baltimore, MD 21205, USA
Cancer Causes Control 16:1189-94. 2005..63; 95% CI 1.40-4.94) than in men who were younger at vasectomy. CONCLUSIONS: The results from this prospective study suggest a positive association between vasectomy and prostate cancer, especially low-grade disease...
Nonsteroidal anti-inflammatory drugs and the risk of developing breast cancer in a population-based prospective cohort study in Washington County, MDLisa Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine, Mercy Medical Center, Baltimore, MD 21202, USA
Int J Cancer 121:211-15. 2007..Overall, findings from this study indicate that NSAID use is associated with a decrease in breast cancer risk and that the reduction in risk is similar for ER-positive and ER-negative tumors...
C-reactive protein and the risk of incident colorectal cancerThomas P Erlinger
Department of Medicine, Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
JAMA 291:585-90. 2004..Inflammation may play a role in the pathogenesis of colorectal cancer; however, epidemiological evidence supporting this hypothesis in average-risk persons is sparse...
Nonsteroidal antiinflammatory drugs, cyclooxygenase polymorphisms, and the risk of developing breast carcinoma among women with benign breast diseaseLisa Gallicchio
Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21202, USA
Cancer 106:1443-52. 2006....
Fatigue in breast cancer survivors: the impact of a mind-body medicine interventionSusan E Appling
Mercy Medical Center, Baltimore, MD, USA
Oncol Nurs Forum 39:278-86. 2012..To evaluate a mind-body medicine (MBM) program for its impact on persistent fatigue following breast cancer treatment...
Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapyLisa Gallicchio
The Prevention and Research Center, The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 St Paul Place, 6th Floor, Baltimore, MD 21202, USA
Breast Cancer Res Treat 130:569-77. 2011..Findings from this study suggest that higher DHEAS concentrations are associated with less AI-associated pain and should be further investigated...
Association between plasma total cholesterol concentration and incident prostate cancer in the CLUE II cohortAlison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Cancer Causes Control 21:61-8. 2010..Our study supports two prior ones suggesting that cholesterol influences risk of high-grade prostate cancer, and indirectly supports the hypothesis that cholesterol-lowering is a mechanism by which statins are protective...
A community-based study of cigarette smoking behavior in relation to variation in three genes involved in dopamine metabolism: Catechol-O-methyltransferase (COMT), dopamine beta-hydroxylase (DBH) and monoamine oxidase-A (MAO-A)Meredith S Shiels
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
Prev Med 47:116-22. 2008..The association between common polymorphisms of these genes and smoking behavior was assessed among 10,059 Caucasian volunteers in Washington County, MD in 1989...
Active and passive cigarette smoking and the risk of cervical neoplasiaCornelia L Trimble
Department of Obstetrics and Gynecology, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Obstet Gynecol 105:174-81. 2005..The results of this long-term, prospective cohort study corroborate the association between active cigarette smoking and cervical neoplasia and provide evidence that passive smoking is a risk factor for cervical neoplasia...
Genetic polymorphisms of peroxisome proliferator-activated receptors and the risk of cardiovascular morbidity and mortality in a community-based cohort in washington county, MarylandL Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 Street Paul Place, 6th Floor, Baltimore, MD 21202, USA
PPAR Res 2008:276581. 2008..Future studies should be conducted to confirm these findings and to explore the associations in populations with greater racial and ethnic diversity...
A population-based study of DNA repair gene variants in relation to non-melanoma skin cancer as a marker of a cancer-prone phenotypeIngo Ruczinski
Department of Biostatistics, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
Carcinogenesis 33:1692-8. 2012..A promising lead is genetic variants in TDG, important not only in base excision repair but also in regulating the epigenome and gene expression, which may contribute to the NMSC-associated increase in overall cancer risk...
Association of markers of insulin and glucose control with subsequent colorectal cancer riskSharon H Saydah
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Cancer Epidemiol Biomarkers Prev 12:412-8. 2003....
The relationship between gender, social support, and health-related quality of life in a community-based study in Washington County, MarylandLisa Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine Mercy Medical Center, Baltimore, MD 21202, USA
Qual Life Res 16:777-86. 2007..The purpose of this study was to determine the factors associated with HRQOL, especially levels of social support, and variation by gender...
WBC count and the risk of cancer mortality in a national sample of U.S. adults: results from the Second National Health and Nutrition Examination Survey mortality studyThomas P Erlinger
Department of Medicine, Johns Hopkins Medical University School of Medicine, Baltimore, MD 21201, USA
Cancer Epidemiol Biomarkers Prev 13:1052-6. 2004..Additional studies are needed to determine whether circulating levels of inflammatory markers are associated with increased risk of incident cancer...
Meat and dairy consumption and subsequent risk of prostate cancer in a US cohort studySabine Rohrmann
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Rm E 6138, Baltimore, MD 21205, USA
Cancer Causes Control 18:41-50. 2007..To evaluate the association of meat and dairy food consumption with subsequent risk of prostate cancer...
Nicotine replacement therapy use among a cohort of smokersAnthony J Alberg
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Addict Dis 24:101-13. 2005..Nicotine replacement therapy (NRT) has been shown to assist smokers to stop smoking in randomized trials, but little is known about its use in the general population...
Prospective study of carotenoids, tocopherols, and retinoid concentrations and the risk of breast cancerReiko Sato
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Cancer Epidemiol Biomarkers Prev 11:451-7. 2002..There was generally a protective association for other micronutrients in both cohorts, although none reached statistical significance. The results suggest that carotenoids may protect against the development of breast cancer...
Active recruitment increased enrollment in a hereditary cancer registryTara M Friebel
Mid-Atlantic Cancer Genetics Network, Department of Pathology, Johns Hopkins University School of Medicine, Park SB202, 600 N. Wolfe St, Baltimore, MD 21287, USA
J Clin Epidemiol 57:1172-6. 2004..6% to 67.4%). CONCLUSION: Allocating research staff specifically for recruitment and personal contact with potential participants is effective in achieving increased enrollment into a national hereditary cancer research registry...
Prediagnostic toenail cadmium and zinc and subsequent prostate cancer riskElizabeth A Platz
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Prostate 52:288-96. 2002..We evaluated the association between prediagnostic toenail cadmium and zinc concentrations and risk of prostate cancer in a cohort in which the primary route of exposure to cadmium and zinc is the diet...
The built environment and obesityMia A Papas
Departmentof Pediatrics, School of Medicine, University of Maryland, 737 West Lombard Street, Baltimore, MD 21201, USA
Epidemiol Rev 29:129-43. 2007....
A new model ELISA, based on two monoclonal antibodies, for quantification of fatty acid synthaseYoung Y Wang
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
J Immunoassay Immunochem 23:279-92. 2002..In summary, this monoclonal-monoclonal FAS-ELISA is sensitive, accurate, and precise in quantification of fatty acid synthase and has potential as a complementary tool in testing clinical samples...
The importance of cytologic intrarater and interrater reproducibility: the case of ductal lavageKala Visvanathan
Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 15:2553-6. 2006..27 +/- 0.09. Fair to moderate intrarater and interrater agreement of DL cytology was observed. Low intrarater and interrater cytologic consistency may compromise the interpretation of clinical studies of DL...
Association among an ornithine decarboxylase polymorphism, androgen receptor gene (CAG) repeat length and prostate cancer riskKala Visvanathan
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
J Urol 171:652-5. 2004..A nested case-control study was done to examine the association between this ODC genotype and prostate cancer risk, and whether it varies by AR gene CAG repeat length and smoking...
Serum antibodies to JC virus, BK virus, simian virus 40, and the risk of incident adult astrocytic brain tumorsDana E M Rollison
Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Cancer Epidemiol Biomarkers Prev 12:460-3. 2003..00 for SV40 (95% CI, 0.30-3.32). Given the high prevalence of JCV and BKV infections and the millions who were potentially exposed to SV40 through contaminated polio vaccines, future studies should attempt to replicate these findings...
Insulin-like growth factor 1 and musculoskeletal pain among breast cancer patients on aromatase inhibitor therapy and women without a history of cancerLisa Gallicchio
The Prevention and Research Center, The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 St Paul Place, 6th Floor, Baltimore, MD, 21202, USA
J Cancer Res Clin Oncol 139:837-43. 2013..Thus, the goal of this study was to examine whether changes in the insulin-like growth factor (IGF) axis were associated with pain among women initiating AI therapy or a comparison group of women without a history of cancer...
Female sexual function and pelvic floor disordersVictoria L Handa
Department of Gynecology and Obstetrics, Johns Hopkins University, Baltimore, Maryland, USA
Obstet Gynecol 111:1045-52. 2008..To investigate the hypothesis that pelvic floor disorders are associated with female sexual problems, independently of other related factors...
Managing the impact of posttreatment fatigue on the family: breast cancer survivors share their experiencesJulianne S Oktay
School of Social Work, University of Maryland, Baltimore, MD 21201, USA
Fam Syst Health 29:127-37. 2011....
Influence of geographic location in modeling blood pesticide levels in a community surrounding a U.S. Environmental protection agency superfund siteShannon H Gaffney
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 113:1712-6. 2005..Spatial information may enable researchers to detect a potential exposure pattern that may not be revealed with only nonspatial variables...
Premenopausal levels of circulating insulin-like growth factor I and the risk of postmenopausal breast cancerDana E Rollison
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Room E 6142, Baltimore, MD 21205, USA
Int J Cancer 118:1279-84. 2006..Age-stratification should be undertaken in larger investigations of IGF-I levels as predictors of postmenopausal breast cancer...
Utilization of BRCA1/2 genetic testing in the clinical setting: report from a single institutionSoo Chin Lee
Department of Oncology, Johns Hopkins Medical Institution, Baltimore, MD 21205, USA
Cancer 94:1876-85. 2002..Clinical testing for BRCA1/2 has been available since 1996. Interest in testing in the research and hypothetical situations has been consistently high, but there have been limited reports on its clinical utilization...
C47T polymorphism in manganese superoxide dismutase (MnSOD), antioxidant intake and survivalJeanine M Genkinger
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, MA, United States
Mech Ageing Dev 127:371-7. 2006..A C47T transition in the MnSOD gene may affect the enzyme's distribution to the mitochondrion, a site of high oxidative stress. We examined the association between this polymorphism and survival...
Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenomaSonja I Berndt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Cancer Res 67:1395-404. 2007..51; 95% CI, 0.33-0.78, P = 0.002 for PARP1 A284A). This study suggests that polymorphisms in APEX1, XRCC1, and PARP1 may be associated with advanced colorectal adenoma...
Processed meat consumption and adult gliomas in a Maryland cohortDana E M Rollison
Cancer Causes Control 15:99-100. 2004
A comparison between real-time polymerase chain reaction and hybrid capture 2 for human papillomavirus DNA quantitationPatti E Gravitt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 12:477-84. 2003..The nonrandom distribution of multiple infections by case-control status and the apparent differential effect of viral load by genotype warrant caution when using HC 2 measurements to infer viral load associations with SIL and cancer...
Markers of past infection with simian virus 40 (SV40) and risk of incident non-Hodgkin lymphoma in a Maryland cohortDana E Rollison
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA
Cancer Epidemiol Biomarkers Prev 14:1448-52. 2005..8% of cases and 1.6% of controls (OR, 1.51; 95% CI, 0.41-5.52). Our findings suggest that past infection with SV40 is not associated with an increased risk of developing NHL...
Contralateral prophylactic mastectomy: quantifying benefits and weighing the harmsKathy J Helzlsouer
J Clin Oncol 23:4251-3. 2005
Good news about oral contraceptivesNancy E Davidson
N Engl J Med 346:2078-9. 2002
Personal hair dye use and cancer: a systematic literature review and evaluation of exposure assessment in studies published since 1992Dana E Rollison
Division of Cancer Prevention and Control, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
J Toxicol Environ Health B Crit Rev 9:413-39. 2006..Replication of these findings is needed to determine whether the reported associations are real or spurious...
Historical comparison of perfluorooctanesulfonate, perfluorooctanoate, and other fluorochemicals in human bloodGeary W Olsen
Medical Department, 3M Company, Mail Stop 220 6W 08, St Paul, MN 55144, USA
Environ Health Perspect 113:539-45. 2005..Comparison with other regional data collected in 2001 did not suggest a continued increase in concentrations since 1989...
Methods for identifying long-term adverse effects of treatment in patients with eye diseases: the Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort StudyJohn H Kempen
Center for Preventive Ophthalmology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Ophthalmic Epidemiol 15:47-55. 2008....
Prediagnostic circulating antibodies to JC and BK human polyomaviruses and risk of non-Hodgkin lymphomaDana E Rollison
H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
Cancer Epidemiol Biomarkers Prev 15:543-50. 2006....
Nonmelanoma skin cancer and risk for subsequent malignancyJiping Chen
Division of Cancer Prevention, National Cancer Institute, Rockville, MD, USA
J Natl Cancer Inst 100:1215-22. 2008..Individuals with a personal history of nonmelanoma skin cancer (NMSC) may have an increased risk of subsequent noncutaneous malignancies. To test this hypothesis, we carried out a community-based, prospective cohort study...
