Debora Williams-HermanSummaryAffiliation: Merck Research Laboratories Country: USA Publications
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Efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes: a 54-week studyDebora Williams-Herman
Merck Research Laboratories, Rahway, NJ 07065, USA
Curr Med Res Opin 25:569-83. 2009..To assess the 54-week efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes and inadequate glycemic control (HbA(1c) 7.5-11%) on diet and exercise...
Safety and tolerability of sitagliptin in clinical studies: a pooled analysis of data from 10,246 patients with type 2 diabetesDebora Williams-Herman
Merck Research Laboratories, Rahway, NJ USA
BMC Endocr Disord 10:7. 2010..The purpose of the present analysis is to update the safety and tolerability assessment of sitagliptin by pooling data from 19 double-blind clinical studies...
Effect of initial combination therapy with sitagliptin and metformin on β-cell function in patients with type 2 diabetesD Williams-Herman
Department of Clinical Research, Merck Sharp and Dohme Corp, Rahway, NJ 07065, USA
Diabetes Obes Metab 14:67-76. 2012..To examine the effect of sitagliptin and metformin, alone and in combination, on modelled parameters of β-cell function in patients with type 2 diabetes...
Lower risk of hypoglycemia with sitagliptin compared to glipizide when either is added to metformin therapy: a pre-specified analysis adjusting for the most recently measured HbA(1c) valueKarl J Krobot
Merck Sharp and Dohme Corp, Whitehouse Station, NJ, USA
Curr Med Res Opin 28:1281-7. 2012..Glycemic efficacy and patient characteristics may influence hypoglycemic events. The present analysis evaluated the risk of hypoglycemia with sitagliptin or glipizide after adjusting for the most recently measured HbA(1c) value...
Efficacy and tolerability of sitagliptin monotherapy in elderly patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trialNir Barzilai
Merck Research Laboratories, Rahway, NJ 07065 0900, USA
Curr Med Res Opin 27:1049-58. 2011..Type 2 diabetes in the elderly is an important and insufficiently studied public health problem. This study evaluated sitagliptin monotherapy in patients with type 2 diabetes aged ≥ 65 years...
