James W Watters

Summary

Affiliation: Merck Research Laboratories
Country: USA

Publications

  1. pmc Multiplexed measurements of gene signatures in different analytes using the Nanostring nCounter Assay System
    Vladislav A Malkov
    Rosetta Inpharmatics, LLC, 401 Terry Ave N, Seattle, WA 98109, USA
    BMC Res Notes 2:80. 2009
  2. pmc EMT is the dominant program in human colon cancer
    Andre Loboda
    Merck, Sharp and Dohme, West Point, PA 19486, USA
    BMC Med Genomics 4:9. 2011
  3. pmc A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors
    Andrey Loboda
    Department of Molecular Profiling and Research Informatics, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    BMC Med Genomics 3:26. 2010
  4. pmc Comparative expression pathway analysis of human and canine mammary tumors
    Paolo Uva
    IRBM P Angeletti, Merck MRL Rome, Pomezia, Italy
    BMC Genomics 10:135. 2009
  5. doi request reprint De novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model
    James W Watters
    Department of Molecular Profiling, Merck Research Laboratories, North Wales, Pennsylvania 19454, USA
    Cancer Res 69:8949-57. 2009

Collaborators

  • Andrey Loboda
  • Andre Loboda
  • Hongyue Dai
  • Vladislav A Malkov
  • Paolo Uva
  • Pearl S Huang
  • Rob A E M Tollenaar
  • Michael V Nebozhyn
  • Laura van't Veer
  • David B Jackson
  • Peter Martin Shaw
  • Deepak Agrawal
  • Carolyne A Buser
  • Timothy J Yeatman
  • Michael Chastain
  • Theresa Zhang
  • Kumiko Nagashima
  • Michael Nebozhyn
  • Rich Klinghoffer
  • Bethany Lynch
  • Brian Roberts
  • Cloud Paweletz
  • Jason Frazier
  • Brian Haines
  • WILLIAM ARTHUR
  • Melissa Chenard
  • Pearl Huang
  • Jannik Andersen
  • Igor Feldman
  • Valentina Viti
  • Gary Geiss
  • Francesca Abramo
  • Gennaro Ciliberto
  • John Castle
  • Laura Marconato
  • Amit Kulkarni
  • Thomas Fare
  • Giuseppe Mesiti
  • Armin Lahm
  • Kyle A Serikawa
  • Valentina Zappulli
  • Luigi Aurisicchio
  • Nicola La Monica
  • Fabio Palombo
  • Afshin Mashadi Hossein
  • Noel Balantac
  • Emanuele De Rinaldis

Detail Information

Publications5

  1. pmc Multiplexed measurements of gene signatures in different analytes using the Nanostring nCounter Assay System
    Vladislav A Malkov
    Rosetta Inpharmatics, LLC, 401 Terry Ave N, Seattle, WA 98109, USA
    BMC Res Notes 2:80. 2009
    ..34-0.41 in log2 scale) for FF total RNA samples. CONCLUSION: The nCounter Analysis System generated robust data for multi-gene expression signatures across three different sample preparation conditions...
  2. pmc EMT is the dominant program in human colon cancer
    Andre Loboda
    Merck, Sharp and Dohme, West Point, PA 19486, USA
    BMC Med Genomics 4:9. 2011
    ..Colon cancer has been classically described by clinicopathologic features that permit the prediction of outcome only after surgical resection and staging...
  3. pmc A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors
    Andrey Loboda
    Department of Molecular Profiling and Research Informatics, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    BMC Med Genomics 3:26. 2010
    ..Therefore, optimal methods for measuring Ras pathway activation are critical. The main focus of our work was to develop a gene expression signature that is predictive of RAS pathway dependence...
  4. pmc Comparative expression pathway analysis of human and canine mammary tumors
    Paolo Uva
    IRBM P Angeletti, Merck MRL Rome, Pomezia, Italy
    BMC Genomics 10:135. 2009
    ....
  5. doi request reprint De novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model
    James W Watters
    Department of Molecular Profiling, Merck Research Laboratories, North Wales, Pennsylvania 19454, USA
    Cancer Res 69:8949-57. 2009
    ....