I Ming Wang

Summary

Affiliation: Merck Research Laboratories
Country: USA

Publications

  1. pmc Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers
    I Ming Wang
    Informatics and Analysis, Merck Research Laboratories, Merck and Co, Inc, West Point, PA 19486, USA
    Mol Syst Biol 8:594. 2012
  2. doi Systems biology approach for new target and biomarker identification
    I Ming Wang
    Informatics and Analysis, Merck Research Laboratory, West Point, PA 19486, USA
    Curr Top Microbiol Immunol 363:169-99. 2013
  3. pmc Transcriptional profiling of vaccine-induced immune responses in humans and non-human primates
    I Ming Wang
    Merck Research Laboratories, West Point, Pennsylvania, USA
    Microb Biotechnol 5:177-87. 2012
  4. pmc Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene
    Jimmy Fourtounis
    Department of Respiratory and Immunology, Merck Research Laboratories, Boston, Massachusetts 02115, USA
    Respir Res 13:92. 2012
  5. doi Transcriptome profiling and network analysis of genetically hypertensive mice identifies potential pharmacological targets of hypertension
    Oscar Puig
    Department of Molecular Profiling Research Informatics, Merck Research Laboratories, Rahway, New Jersey 07065, USA
    Physiol Genomics 42:24-32. 2010
  6. doi Genomic and systems approaches to translational biomarker discovery in immunological diseases
    Kenzie D Macisaac
    Informatics and Analysis, Merck and Co Inc, 33 Avenue Louis Pasteur, Boston, MA 02115, USA
    Drug Discov Today 19:133-9. 2014

Detail Information

Publications6

  1. pmc Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers
    I Ming Wang
    Informatics and Analysis, Merck Research Laboratories, Merck and Co, Inc, West Point, PA 19486, USA
    Mol Syst Biol 8:594. 2012
    ..The identification of this inflammatome signature, its network architecture, and key drivers not only highlights the shared etiology but also pinpoints potential targets for intervention of various common diseases...
  2. doi Systems biology approach for new target and biomarker identification
    I Ming Wang
    Informatics and Analysis, Merck Research Laboratory, West Point, PA 19486, USA
    Curr Top Microbiol Immunol 363:169-99. 2013
    ....
  3. pmc Transcriptional profiling of vaccine-induced immune responses in humans and non-human primates
    I Ming Wang
    Merck Research Laboratories, West Point, Pennsylvania, USA
    Microb Biotechnol 5:177-87. 2012
    ..This review aims to give an overview of the current literature on immunoprofiling studies in humans and also presents some of our own data on profiling of licensed and experimental vaccines in non-human primates...
  4. pmc Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene
    Jimmy Fourtounis
    Department of Respiratory and Immunology, Merck Research Laboratories, Boston, Massachusetts 02115, USA
    Respir Res 13:92. 2012
    ..To better understand the role the NRF2 pathway has on respiratory disease we have taken a novel approach to define NRF2 dependent gene expression in a relevant lung system...
  5. doi Transcriptome profiling and network analysis of genetically hypertensive mice identifies potential pharmacological targets of hypertension
    Oscar Puig
    Department of Molecular Profiling Research Informatics, Merck Research Laboratories, Rahway, New Jersey 07065, USA
    Physiol Genomics 42:24-32. 2010
    ..The integration of data from gene expression profiling and genetics networks is a valuable approach to identify novel potential targets for the pharmacological treatment of hypertension...
  6. doi Genomic and systems approaches to translational biomarker discovery in immunological diseases
    Kenzie D Macisaac
    Informatics and Analysis, Merck and Co Inc, 33 Avenue Louis Pasteur, Boston, MA 02115, USA
    Drug Discov Today 19:133-9. 2014
    ....