Affiliation: Merck Research Laboratories
- Effect of morphine and pregabalin compared with diphenhydramine hydrochloride and placebo on hyperalgesia and allodynia induced by intradermal capsaicin in healthy male subjectsHao Wang
Department of Experimental Medicine, Merck Research Laboratories, North Wales, PA 19454 2505, USA
J Pain 9:1088-95. 2008..This platform may provide a means to rapidly assess new analgesics and enhance dose selection and decision-making during clinical development...
- Impact of responder definition on the enriched enrollment randomized withdrawal trial design for establishing proof of concept in neuropathic painDavid J Hewitt
Merck Research Laboratories, White house Station, NJ 19454, USA
Pain 152:514-21. 2011....
- Identification and characterization of 4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an orally bioavailable, brain penetrant NR2B selective N-methyl-D-aspartate receptor antagonistNigel J Liverton
Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
J Med Chem 50:807-19. 2007..Compound 20j demonstrated efficacy in in vivo rodent models of antinociception, allodynia, and Parkinson's disease...