Hao Wang

Summary

Affiliation: Merck Research Laboratories
Country: USA

Publications

  1. ncbi Effect of morphine and pregabalin compared with diphenhydramine hydrochloride and placebo on hyperalgesia and allodynia induced by intradermal capsaicin in healthy male subjects
    Hao Wang
    Department of Experimental Medicine, Merck Research Laboratories, North Wales, PA 19454 2505, USA
    J Pain 9:1088-95. 2008
  2. ncbi Impact of responder definition on the enriched enrollment randomized withdrawal trial design for establishing proof of concept in neuropathic pain
    David J Hewitt
    Merck Research Laboratories, White house Station, NJ 19454, USA
    Pain 152:514-21. 2011
  3. ncbi Identification and characterization of 4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an orally bioavailable, brain penetrant NR2B selective N-methyl-D-aspartate receptor antagonist
    Nigel J Liverton
    Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    J Med Chem 50:807-19. 2007

Detail Information

Publications3

  1. ncbi Effect of morphine and pregabalin compared with diphenhydramine hydrochloride and placebo on hyperalgesia and allodynia induced by intradermal capsaicin in healthy male subjects
    Hao Wang
    Department of Experimental Medicine, Merck Research Laboratories, North Wales, PA 19454 2505, USA
    J Pain 9:1088-95. 2008
    ..This platform may provide a means to rapidly assess new analgesics and enhance dose selection and decision-making during clinical development...
  2. ncbi Impact of responder definition on the enriched enrollment randomized withdrawal trial design for establishing proof of concept in neuropathic pain
    David J Hewitt
    Merck Research Laboratories, White house Station, NJ 19454, USA
    Pain 152:514-21. 2011
    ....
  3. ncbi Identification and characterization of 4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an orally bioavailable, brain penetrant NR2B selective N-methyl-D-aspartate receptor antagonist
    Nigel J Liverton
    Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    J Med Chem 50:807-19. 2007
    ..Compound 20j demonstrated efficacy in in vivo rodent models of antinociception, allodynia, and Parkinson's disease...