Katie J Turner

Summary

Affiliation: Merck Research Laboratories
Country: USA

Publications

  1. ncbi request reprint Altered gene expression during rat Wolffian duct development in response to in utero exposure to the antiandrogen linuron
    Katie J Turner
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709 2137, USA
    Toxicol Sci 74:114-28. 2003
  2. ncbi request reprint Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat
    Christopher J Bowman
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 74:393-406. 2003
  3. ncbi request reprint Altered gene expression during rat Wolffian duct development following di(n-butyl) phthalate exposure
    Christopher J Bowman
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 86:161-74. 2005
  4. ncbi request reprint Preliminary investigation of changes in the sexually dimorphic nucleus of the rat medial preoptic area following prenatal exposure to fenitrothion
    Melanie F Struve
    CIIT Centers for Health Research, The Hamner Institutes for Health Sciences, Research Triangle Park, NC 27709 2137, USA
    J Appl Toxicol 27:631-6. 2007
  5. ncbi request reprint Assessment of developmental toxicity of vorinostat, a histone deacetylase inhibitor, in Sprague-Dawley rats and Dutch Belted rabbits
    L David Wise
    Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    Birth Defects Res B Dev Reprod Toxicol 80:57-68. 2007
  6. ncbi request reprint Effects of in utero exposure to the organophosphate insecticide fenitrothion on androgen-dependent reproductive development in the Crl:CD(SD)BR rat
    Katie J Turner
    CIIT Centers for Health Research, P O Box 12137, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 68:174-83. 2002
  7. ncbi request reprint Inhibin B as a potential biomarker of testicular toxicity
    Jane Stewart
    Reproductive Toxicology, AstraZeneca Pharmaceuticals, Alderley Park, Macclesfield, Cheshire, UK
    Cancer Biomark 1:75-91. 2005

Detail Information

Publications7

  1. ncbi request reprint Altered gene expression during rat Wolffian duct development in response to in utero exposure to the antiandrogen linuron
    Katie J Turner
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709 2137, USA
    Toxicol Sci 74:114-28. 2003
    ..The EGF, Notch, IGF-1, BMP4, and FGF signaling pathways may be involved in normal testosterone-mediated development of the Wolffian duct...
  2. ncbi request reprint Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat
    Christopher J Bowman
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 74:393-406. 2003
    ..In summary, prenatal exposure to finasteride specifically inhibited DHT-mediated development with little to no change in T-mediated development...
  3. ncbi request reprint Altered gene expression during rat Wolffian duct development following di(n-butyl) phthalate exposure
    Christopher J Bowman
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 86:161-74. 2005
    ....
  4. ncbi request reprint Preliminary investigation of changes in the sexually dimorphic nucleus of the rat medial preoptic area following prenatal exposure to fenitrothion
    Melanie F Struve
    CIIT Centers for Health Research, The Hamner Institutes for Health Sciences, Research Triangle Park, NC 27709 2137, USA
    J Appl Toxicol 27:631-6. 2007
    ..These SDN-POA volume changes contrast with those seen with flutamide, another potent anti-androgen, and suggest that fenitrothion may have mixed endocrine effects on the developing brain...
  5. ncbi request reprint Assessment of developmental toxicity of vorinostat, a histone deacetylase inhibitor, in Sprague-Dawley rats and Dutch Belted rabbits
    L David Wise
    Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    Birth Defects Res B Dev Reprod Toxicol 80:57-68. 2007
    ..Range-finding studies established oral dose levels of 5, 15, or 50 mg/kg/day and 20, 50, or 150 mg/kg/day in rats and rabbits, respectively...
  6. ncbi request reprint Effects of in utero exposure to the organophosphate insecticide fenitrothion on androgen-dependent reproductive development in the Crl:CD(SD)BR rat
    Katie J Turner
    CIIT Centers for Health Research, P O Box 12137, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 68:174-83. 2002
    ..Based on observed fetotoxicity at 20 mg/kg/day, the lowest observed adverse effect level (LOAEL) for developmental effects can be lowered from 25 to 20 mg/kg/day...
  7. ncbi request reprint Inhibin B as a potential biomarker of testicular toxicity
    Jane Stewart
    Reproductive Toxicology, AstraZeneca Pharmaceuticals, Alderley Park, Macclesfield, Cheshire, UK
    Cancer Biomark 1:75-91. 2005
    ..An international, intercompany project has been initiated to evaluate the overall suitability and limitations of inhibin B as a biomarker of testicular toxicity...