Affiliation: Merck Research Laboratories
- Progranulin is a chemoattractant for microglia and stimulates their endocytic activityFiona Pickford
Department of Neuroscience Drug Discovery, Merck Research Laboratories, Boston, Massachusetts 02115, USA
Am J Pathol 178:284-95. 2011..These data demonstrate that progranulin acts as a chemoattractant in the brain to recruit or activate microglia and can increase endocytosis of extracellular peptides such as amyloid β...