Gregory P Geba

Summary

Affiliation: Merck Research Laboratories
Country: USA

Publications

  1. ncbi request reprint Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee: a randomized trial
    Gregory P Geba
    Merck and Co Inc, US Human Health, PO Box 4, West Point, PA 19486 0004, USA
    JAMA 287:64-71. 2002
  2. ncbi request reprint Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials
    Wendy P Battisti
    Merck and Co, Inc, West Point, Pennsylvania 19486, USA
    J Pain 5:511-20. 2004
  3. ncbi request reprint The analgesic efficacy of etoricoxib compared with oxycodone/acetaminophen in an acute postoperative pain model: a randomized, double-blind clinical trial
    David J Chang
    Merck and Co Inc, West Point, PA, USA
    Anesth Analg 99:807-15, table of contents. 2004
  4. ncbi request reprint Comparison of rofecoxib and a multidose oxycodone/ acetaminophen regimen for the treatment of acute pain following oral surgery: a randomized controlled trial
    David J Chang
    Merck and Co, Inc, West Point, PA 19486 0004, USA
    Curr Med Res Opin 20:939-49. 2004
  5. ncbi request reprint Comparison of the analgesic efficacy of rofecoxib and enteric-coated diclofenac sodium in the treatment of postoperative dental pain: a randomized, placebo-controlled clinical trial
    David J Chang
    Merck and Co, Inc, West Point, Pennsylvania, 19486 0004, USA
    Clin Ther 24:490-503. 2002
  6. ncbi request reprint Treatment of patients with osteoarthritis with rofecoxib compared with nabumetone
    Arthur L Weaver
    University of Nebraska Medical Center, Omaha, Nebraska, USA
    J Clin Rheumatol 12:17-25. 2006
  7. ncbi request reprint Efficacy of rofecoxib, celecoxib, and acetaminophen in patients with osteoarthritis of the knee. A combined analysis of the VACT studies
    Thomas J Schnitzer
    Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Rheumatol 32:1093-105. 2005
  8. ncbi request reprint The time to onset and overall analgesic efficacy of rofecoxib 50 mg: a meta-analysis of 13 randomized clinical trials
    Paul J Desjardins
    SCIREX Corporation, Austin, TX, USA
    Clin J Pain 21:241-50. 2005
  9. ncbi request reprint Treatment of chronic low back pain with etoricoxib, a new cyclo-oxygenase-2 selective inhibitor: improvement in pain and disability--a randomized, placebo-controlled, 3-month trial
    Charles A Birbara
    University of Massachusetts School of Medicine, Worcester, MA, USA
    J Pain 4:307-15. 2003
  10. ncbi request reprint Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: a randomized, controlled trial
    Jeffrey R Lisse
    University of Arizona, Tuscon, USA
    Ann Intern Med 139:539-46. 2003

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee: a randomized trial
    Gregory P Geba
    Merck and Co Inc, US Human Health, PO Box 4, West Point, PA 19486 0004, USA
    JAMA 287:64-71. 2002
    ..Osteoarthritis (OA) is often treated with nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen, or specific inhibitors of cyclooxygenase 2 (COX-2)...
  2. ncbi request reprint Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials
    Wendy P Battisti
    Merck and Co, Inc, West Point, Pennsylvania 19486, USA
    J Pain 5:511-20. 2004
    ..5 mg (P = .01) compared with nabumetone. Rofecoxib treatment, with its faster onset of OA efficacy and lower rates of related discontinuations, might provide efficacy advantages in the treatment of OA pain...
  3. ncbi request reprint The analgesic efficacy of etoricoxib compared with oxycodone/acetaminophen in an acute postoperative pain model: a randomized, double-blind clinical trial
    David J Chang
    Merck and Co Inc, West Point, PA, USA
    Anesth Analg 99:807-15, table of contents. 2004
    ..In conclusion, etoricoxib 120 mg provided superior overall efficacy compared with oxycodone/acetaminophen 10/650 mg and was associated with significantly fewer AEs...
  4. ncbi request reprint Comparison of rofecoxib and a multidose oxycodone/ acetaminophen regimen for the treatment of acute pain following oral surgery: a randomized controlled trial
    David J Chang
    Merck and Co, Inc, West Point, PA 19486 0004, USA
    Curr Med Res Opin 20:939-49. 2004
    ..Onset of analgesic effect, peak analgesic single dose of oxycodone/acetaminophen. effect, and duration of analgesic effect were also evaluated. Adverse experiences were recorded...
  5. ncbi request reprint Comparison of the analgesic efficacy of rofecoxib and enteric-coated diclofenac sodium in the treatment of postoperative dental pain: a randomized, placebo-controlled clinical trial
    David J Chang
    Merck and Co, Inc, West Point, Pennsylvania, 19486 0004, USA
    Clin Ther 24:490-503. 2002
    ....
  6. ncbi request reprint Treatment of patients with osteoarthritis with rofecoxib compared with nabumetone
    Arthur L Weaver
    University of Nebraska Medical Center, Omaha, Nebraska, USA
    J Clin Rheumatol 12:17-25. 2006
    ..Rofecoxib and nabumetone were developed to provide gastrointestinal benefits over traditional nonsteroidal antiinflammatory drugs (NSAIDs). However, there is limited comparative information relating to these 2 drugs...
  7. ncbi request reprint Efficacy of rofecoxib, celecoxib, and acetaminophen in patients with osteoarthritis of the knee. A combined analysis of the VACT studies
    Thomas J Schnitzer
    Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Rheumatol 32:1093-105. 2005
    ..5 mg (n=259), or rofecoxib 25 mg (n=527) in a double blind trial [Vioxx, Acetaminophen, Celecoxib Trial (VACT2)]. Results were also pooled with the similarly designed VACT1 trial...
  8. ncbi request reprint The time to onset and overall analgesic efficacy of rofecoxib 50 mg: a meta-analysis of 13 randomized clinical trials
    Paul J Desjardins
    SCIREX Corporation, Austin, TX, USA
    Clin J Pain 21:241-50. 2005
    ..To determine the time to onset of analgesia of rofecoxib based on a patient-level meta-analysis of randomized, placebo-controlled, postoperative oral surgery pain studies...
  9. ncbi request reprint Treatment of chronic low back pain with etoricoxib, a new cyclo-oxygenase-2 selective inhibitor: improvement in pain and disability--a randomized, placebo-controlled, 3-month trial
    Charles A Birbara
    University of Massachusetts School of Medicine, Worcester, MA, USA
    J Pain 4:307-15. 2003
    ..Etoricoxib given once daily provided significant relief of symptoms, and disability associated with chronic LBP that was observed 1 week after initiating therapy, was maximal at 4 weeks, and was maintained over 3 months...
  10. ncbi request reprint Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: a randomized, controlled trial
    Jeffrey R Lisse
    University of Arizona, Tuscon, USA
    Ann Intern Med 139:539-46. 2003
    ..Unlike NSAIDs, rofecoxib targets only the COX-2 isoform...
  11. ncbi request reprint Efficacy and safety of rofecoxib 12.5 mg versus nabumetone 1,000 mg in patients with osteoarthritis of the knee: a randomized controlled trial
    Alan J Kivitz
    Altoona Center for Clinical Research, Duncansville, Pennsylvania, USA
    J Am Geriatr Soc 52:666-74. 2004
    ..To evaluate the use of starting doses of rofecoxib and nabumetone in patients with osteoarthritis (OA) of the knee...
  12. ncbi request reprint Efficacy and safety profile of treatment with etoricoxib 120 mg once daily compared with indomethacin 50 mg three times daily in acute gout: a randomized controlled trial
    Bernard R Rubin
    University of North Texas, Fort Worth, TX, USA
    Arthritis Rheum 50:598-606. 2004
    ..To evaluate the efficacy and safety of etoricoxib and indomethacin in the treatment of patients with acute gout...
  13. ncbi request reprint Cyclooxygenase 2 activity modulates the severity of murine Lyme arthritis
    Juan Anguita
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    FEMS Immunol Med Microbiol 34:187-91. 2002
    ..burgdorferi-specific antibody or cytokine responses. Cox-2 activity is therefore associated with the genesis of infectious arthritis caused by B. burgdorferi...
  14. ncbi request reprint Effect of omalizumab on the need for rescue systemic corticosteroid treatment in patients with moderate-to-severe persistent IgE-mediated allergic asthma: a pooled analysis
    William W Busse
    University of Wisconsin, Madison, WI, USA
    Curr Med Res Opin 23:2379-86. 2007
    ..We investigated the effect of omalizumab on asthma outcomes in a retrospective pooled analysis of data from phase III clinical trials in patients (>or= 12 years) with moderate-to-severe persistent IgE-mediated allergic asthma...
  15. doi request reprint Response of older patients with IgE-mediated asthma to omalizumab: a pooled analysis
    Robert J Maykut
    Novartis Pharmaceuticals Corporation, US Clinical Development and Medical Affairs, East Hanover, New Jersey 07936, USA
    J Asthma 45:173-81. 2008
    ....