T P Bonnert

Summary

Affiliation: Merck Research Laboratories
Country: USA

Publications

  1. ncbi The cloning and characterization of human MyD88: a member of an IL-1 receptor related family
    T P Bonnert
    Immunex Corporation, Seattle, WA 98101, USA
    FEBS Lett 402:81-4. 1997
  2. ncbi Cloning of a putative ligand for the T1/ST2 receptor
    M A Gayle
    Immunex Corporation, Seattle, Washington 98101, USA
    J Biol Chem 271:5784-9. 1996
  3. ncbi IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP
    P Parnet
    Immunex Corporation, Seattle, Washington 98101, USA
    J Biol Chem 271:3967-70. 1996
  4. ncbi T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family
    J L Mitcham
    Immunex Corporation, Seattle, Washington 98101, USA
    J Biol Chem 271:5777-83. 1996
  5. ncbi Overexpression of the GABA(A) receptor epsilon subunit results in insensitivity to anaesthetics
    S A Thompson
    Merck Sharp and Dohme Research Laboratories, Terlings Park, Harlow CM20 2QR, UK
    Neuropharmacology 43:662-8. 2002
  6. ncbi Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors
    N Brown
    Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR, UK
    Br J Pharmacol 136:965-74. 2002
  7. ncbi theta, a novel gamma-aminobutyric acid type A receptor subunit
    T P Bonnert
    Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Eastwick Road, Harlow, Essex CM20 2QR, England, UK
    Proc Natl Acad Sci U S A 96:9891-6. 1999
  8. ncbi Molecular and functional diversity of the expanding GABA-A receptor gene family
    P J Whiting
    Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Harlow, Essex, England, UK
    Ann N Y Acad Sci 868:645-53. 1999
  9. ncbi Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
    L M Camargo
    Merck Research Labs, Merck and Co, Boston, MA 02115, USA
    Mol Psychiatry 12:74-86. 2007
  10. ncbi Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties [corrected; erratum to be published]
    P J Whiting
    Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Harlow, Essex CM20 2QR, United Kingdom
    J Neurosci 17:5027-37. 1997

Collaborators

Detail Information

Publications10

  1. ncbi The cloning and characterization of human MyD88: a member of an IL-1 receptor related family
    T P Bonnert
    Immunex Corporation, Seattle, WA 98101, USA
    FEBS Lett 402:81-4. 1997
    ..Human MyD88 cDNA is encoded by 5 exons, and maps to chromosome 3p21.3-p22 by fluorescence in situ hybridization (FISH). Overexpression of the death domain region leads to transcriptional activation of the IL-8 promoter...
  2. ncbi Cloning of a putative ligand for the T1/ST2 receptor
    M A Gayle
    Immunex Corporation, Seattle, Washington 98101, USA
    J Biol Chem 271:5784-9. 1996
    ..In searching for a ligand for T1/ST2, we have cloned a cell surface protein to which it binds. This protein is unable to initiate signal transduction by the T1/ST2 receptor in several in vitro assays...
  3. ncbi IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP
    P Parnet
    Immunex Corporation, Seattle, Washington 98101, USA
    J Biol Chem 271:3967-70. 1996
    ....
  4. ncbi T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family
    J L Mitcham
    Immunex Corporation, Seattle, Washington 98101, USA
    J Biol Chem 271:5777-83. 1996
    ..All three assays were positive in response to the T1/ST2 chimera, while the MyD88 and rsc786 chimeras failed to respond. These data indicate that the sequence homology between IL-1RI and T1/ST2 indicates a functional homology as well...
  5. ncbi Overexpression of the GABA(A) receptor epsilon subunit results in insensitivity to anaesthetics
    S A Thompson
    Merck Sharp and Dohme Research Laboratories, Terlings Park, Harlow CM20 2QR, UK
    Neuropharmacology 43:662-8. 2002
    ....
  6. ncbi Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors
    N Brown
    Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR, UK
    Br J Pharmacol 136:965-74. 2002
    ..With its restricted distribution within the brain and unique pharmacology this receptor may play an important role in the action of neurosteroids and anaesthetics. British Journal of Pharmacology (2002) 136, 965-974..
  7. ncbi theta, a novel gamma-aminobutyric acid type A receptor subunit
    T P Bonnert
    Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Eastwick Road, Harlow, Essex CM20 2QR, England, UK
    Proc Natl Acad Sci U S A 96:9891-6. 1999
    ..This subunit has a unique distribution, with studies so far suggesting significant expression within monoaminergic neurons of both human and monkey brain...
  8. ncbi Molecular and functional diversity of the expanding GABA-A receptor gene family
    P J Whiting
    Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Harlow, Essex, England, UK
    Ann N Y Acad Sci 868:645-53. 1999
    ..The structure, function, and distribution of theta-containing receptors, and receptors containing the recently reported epsilon subunit, are described...
  9. ncbi Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
    L M Camargo
    Merck Research Labs, Merck and Co, Boston, MA 02115, USA
    Mol Psychiatry 12:74-86. 2007
    ....
  10. ncbi Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties [corrected; erratum to be published]
    P J Whiting
    Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Harlow, Essex CM20 2QR, United Kingdom
    J Neurosci 17:5027-37. 1997
    ....