JENNIFER ZALLEN

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. pmc Deciphering the genetic code of morphogenesis using functional genomics
    Athea Vichas
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
    J Biol 8:76. 2009
  2. pmc Multicellular dynamics during epithelial elongation
    Jennifer A Zallen
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Semin Cell Dev Biol 19:263-70. 2008
  3. pmc Morphogenesis in Kyoto: a confluence of cell and developmental biology
    Jennifer A Zallen
    Howard Hughes Medical Institute and the Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Mol Biol Cell 21:845-7. 2010
  4. ncbi request reprint Planar polarity and tissue morphogenesis
    Jennifer A Zallen
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
    Cell 129:1051-63. 2007
  5. ncbi request reprint Multicellular rosette formation links planar cell polarity to tissue morphogenesis
    J Todd Blankenship
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10021, USA
    Dev Cell 11:459-70. 2006
  6. pmc Junctional trafficking and epithelial morphogenesis
    Frederik Wirtz-Peitz
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Curr Opin Genet Dev 19:350-6. 2009
  7. pmc Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation
    Sérgio de Matos Simões
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
    Dev Cell 19:377-88. 2010
  8. ncbi request reprint The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identity
    J Todd Blankenship
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10021, USA
    J Cell Sci 120:3099-110. 2007
  9. ncbi request reprint Epithelial organization: may the force be with you
    Rodrigo Fernandez-Gonzalez
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10065, USA
    Curr Biol 18:R163-5. 2008
  10. pmc Myosin II dynamics are regulated by tension in intercalating cells
    Rodrigo Fernandez-Gonzalez
    Howard Hughes Medical Institute, Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065 USA
    Dev Cell 17:736-43. 2009

Research Grants

  1. Molecular control of tissue morphogenesis
    Jennifer A Zallen; Fiscal Year: 2010
  2. Molecular control of tissue morphogenesis
    JENNIFER ZALLEN; Fiscal Year: 2007
  3. Molecular control of tissue morphogenesis
    JENNIFER ZALLEN; Fiscal Year: 2009

Collaborators

  • Alpha S Yap
  • Suzanne Eaton
  • J Todd Blankenship
  • Rodrigo Fernandez-Gonzalez
  • Sérgio de Matos Simões
  • Frederik Wirtz-Peitz
  • Athea Vichas
  • Rachel E Dawes-Hoang
  • Masako Tamada
  • Dene L Farrell
  • Ori Weitz
  • Jens Christian Röper
  • Eric F Wieschaus

Detail Information

Publications15

  1. pmc Deciphering the genetic code of morphogenesis using functional genomics
    Athea Vichas
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
    J Biol 8:76. 2009
    ..A recent study in BMC Biology combines gene expression profiling, bioinformatics and functional analysis to identify genes that shape the Drosophila embryo...
  2. pmc Multicellular dynamics during epithelial elongation
    Jennifer A Zallen
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Semin Cell Dev Biol 19:263-70. 2008
    ..Quantitative analysis of cell behavior in living embryos reveals unexpected cell population dynamics that include the formation of multicellular rosette structures as well as local neighbor exchange...
  3. pmc Morphogenesis in Kyoto: a confluence of cell and developmental biology
    Jennifer A Zallen
    Howard Hughes Medical Institute and the Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Mol Biol Cell 21:845-7. 2010
    ..A recent meeting in Kyoto on "Building the Body Plan: How Cell Adhesion, Signaling, and Cytoskeletal Regulation Shape Morphogenesis" highlighted recent advances in tackling this challenging problem...
  4. ncbi request reprint Planar polarity and tissue morphogenesis
    Jennifer A Zallen
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
    Cell 129:1051-63. 2007
    ....
  5. ncbi request reprint Multicellular rosette formation links planar cell polarity to tissue morphogenesis
    J Todd Blankenship
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10021, USA
    Dev Cell 11:459-70. 2006
    ..We propose that the generation of higher-order rosette structures links local cell interactions to global tissue reorganization during morphogenesis...
  6. pmc Junctional trafficking and epithelial morphogenesis
    Frederik Wirtz-Peitz
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Curr Opin Genet Dev 19:350-6. 2009
    ..Here we describe recent progress in understanding the roles of the vesicle transport machinery in regulating cell adhesion and junctional dynamics during epithelial morphogenesis in vivo...
  7. pmc Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation
    Sérgio de Matos Simões
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
    Dev Cell 19:377-88. 2010
    ..These results demonstrate that Rho-kinase plays an instructive role in planar polarity by targeting Baz/Par-3 and myosin II to complementary cortical domains...
  8. ncbi request reprint The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identity
    J Todd Blankenship
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10021, USA
    J Cell Sci 120:3099-110. 2007
    ..These results suggest that epithelial polarity in the Drosophila embryo is actively maintained by exocyst-dependent apical localization of the Crumbs transmembrane protein...
  9. ncbi request reprint Epithelial organization: may the force be with you
    Rodrigo Fernandez-Gonzalez
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10065, USA
    Curr Biol 18:R163-5. 2008
    ..A recent study in Drosophila combines physical modeling with experimental measurements and mechanical perturbations to shed light on the processes that influence cell patterns in vivo...
  10. pmc Myosin II dynamics are regulated by tension in intercalating cells
    Rodrigo Fernandez-Gonzalez
    Howard Hughes Medical Institute, Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065 USA
    Dev Cell 17:736-43. 2009
    ..These results demonstrate that myosin II dynamics are regulated by tension in a positive feedback loop that leads to multicellular actomyosin cable formation and efficient tissue elongation...
  11. ncbi request reprint Cell mechanics and feedback regulation of actomyosin networks
    Rodrigo Fernandez-Gonzalez
    Howard Hughes Medical Institute and the Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
    Sci Signal 2:pe78. 2009
    ..New evidence from Drosophila demonstrates that these forces are spatially organized by a combination of biochemical and mechanical signals that provide dynamic feedback in a complex cellular environment...
  12. ncbi request reprint Patterned gene expression directs bipolar planar polarity in Drosophila
    Jennifer A Zallen
    Department of Molecular Biology, Princeton University, Lewis Thomas Lab, Washington Road, Princeton, NJ 08544, USA
    Dev Cell 6:343-55. 2004
    ..These results indicate that spatial patterns of gene expression coordinate planar polarity across a multicellular population through the localized distribution of proteins required for cell movement...
  13. pmc SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila
    Jennifer A Zallen
    Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
    J Cell Biol 156:689-701. 2002
    ....
  14. ncbi request reprint Bringing classical embryology to C elegans gastrulation
    Rachel E Dawes-Hoang
    Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA
    Dev Cell 4:6-8. 2003
    ..The resulting detailed analysis of cell behavior will ultimately extend to broader issues, such as, whether morphogenesis can be described as the sum of single-cell events or if unique phenomena emerge at the multicellular level...

Research Grants4

  1. Molecular control of tissue morphogenesis
    Jennifer A Zallen; Fiscal Year: 2010
    ....
  2. Molecular control of tissue morphogenesis
    JENNIFER ZALLEN; Fiscal Year: 2007
    ....
  3. Molecular control of tissue morphogenesis
    JENNIFER ZALLEN; Fiscal Year: 2009
    ....