Research Topics
Genomes and GenesSpecies | JENNIFER ZALLENSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
Research Grants
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Detail Information
Publications
Deciphering the genetic code of morphogenesis using functional genomicsAthea Vichas
Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
J Biol 8:76. 2009..A recent study in BMC Biology combines gene expression profiling, bioinformatics and functional analysis to identify genes that shape the Drosophila embryo...- Multicellular dynamics during epithelial elongationJennifer A Zallen
Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
Semin Cell Dev Biol 19:263-70. 2008..Quantitative analysis of cell behavior in living embryos reveals unexpected cell population dynamics that include the formation of multicellular rosette structures as well as local neighbor exchange... - Morphogenesis in Kyoto: a confluence of cell and developmental biologyJennifer A Zallen
Howard Hughes Medical Institute and the Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
Mol Biol Cell 21:845-7. 2010..A recent meeting in Kyoto on "Building the Body Plan: How Cell Adhesion, Signaling, and Cytoskeletal Regulation Shape Morphogenesis" highlighted recent advances in tackling this challenging problem... 
Planar polarity and tissue morphogenesisJennifer A Zallen
Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
Cell 129:1051-63. 2007....- Multicellular rosette formation links planar cell polarity to tissue morphogenesisJ Todd Blankenship
Developmental Biology Program, Sloan Kettering Institute, New York, New York 10021, USA
Dev Cell 11:459-70. 2006..We propose that the generation of higher-order rosette structures links local cell interactions to global tissue reorganization during morphogenesis... - Junctional trafficking and epithelial morphogenesisFrederik Wirtz-Peitz
Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
Curr Opin Genet Dev 19:350-6. 2009..Here we describe recent progress in understanding the roles of the vesicle transport machinery in regulating cell adhesion and junctional dynamics during epithelial morphogenesis in vivo... - Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongationSérgio de Matos Simões
Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
Dev Cell 19:377-88. 2010..These results demonstrate that Rho-kinase plays an instructive role in planar polarity by targeting Baz/Par-3 and myosin II to complementary cortical domains... - The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identityJ Todd Blankenship
Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10021, USA
J Cell Sci 120:3099-110. 2007..These results suggest that epithelial polarity in the Drosophila embryo is actively maintained by exocyst-dependent apical localization of the Crumbs transmembrane protein... 
Epithelial organization: may the force be with youRodrigo Fernandez-Gonzalez
Developmental Biology Program, Sloan Kettering Institute, New York, New York 10065, USA
Curr Biol 18:R163-5. 2008..A recent study in Drosophila combines physical modeling with experimental measurements and mechanical perturbations to shed light on the processes that influence cell patterns in vivo...- Myosin II dynamics are regulated by tension in intercalating cellsRodrigo Fernandez-Gonzalez
Howard Hughes Medical Institute, Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065 USA
Dev Cell 17:736-43. 2009..These results demonstrate that myosin II dynamics are regulated by tension in a positive feedback loop that leads to multicellular actomyosin cable formation and efficient tissue elongation... - Cell mechanics and feedback regulation of actomyosin networksRodrigo Fernandez-Gonzalez
Howard Hughes Medical Institute and the Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
Sci Signal 2:pe78. 2009..New evidence from Drosophila demonstrates that these forces are spatially organized by a combination of biochemical and mechanical signals that provide dynamic feedback in a complex cellular environment... - Patterned gene expression directs bipolar planar polarity in DrosophilaJennifer A Zallen
Department of Molecular Biology, Princeton University, Lewis Thomas Lab, Washington Road, Princeton, NJ 08544, USA
Dev Cell 6:343-55. 2004..These results indicate that spatial patterns of gene expression coordinate planar polarity across a multicellular population through the localized distribution of proteins required for cell movement... - SCAR is a primary regulator of Arp2/3-dependent morphological events in DrosophilaJennifer A Zallen
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
J Cell Biol 156:689-701. 2002.... - Bringing classical embryology to C elegans gastrulationRachel E Dawes-Hoang
Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA
Dev Cell 4:6-8. 2003..The resulting detailed analysis of cell behavior will ultimately extend to broader issues, such as, whether morphogenesis can be described as the sum of single-cell events or if unique phenomena emerge at the multicellular level...
Research Grants
- Molecular control of tissue morphogenesisJENNIFER ZALLEN; Fiscal Year: 2007....
- Molecular control of tissue morphogenesisJennifer A Zallen; Fiscal Year: 2010....