Thomas Wiesner

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. doi request reprint [Morphological and genetic aspects of Spitz tumors]
    T Wiesner
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 415 E 68th Street, 10065, New York, NY, USA
    Pathologe 36:37-43, 45. 2015
  2. pmc Germline mutations in BAP1 predispose to melanocytic tumors
    Thomas Wiesner
    Department of Dermatology, Medical University of Graz, Graz, Austria
    Nat Genet 43:1018-21. 2011
  3. doi request reprint Clinical and pathologic findings of Spitz nevi and atypical Spitz tumors with ALK fusions
    Klaus J Busam
    Department of Pathology Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY Dermatopathologie Friedrichshafen, Friedrichshafen, Germany Department of Dermatology, Medical University Graz, Graz, Austria
    Am J Surg Pathol 38:925-33. 2014
  4. pmc A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression
    Thomas Wiesner
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 36:818-30. 2012
  5. doi request reprint Combined BRAF(V600E)-positive melanocytic lesions with large epithelioid cells lacking BAP1 expression and conventional nevomelanocytes
    Klaus J Busam
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 37:193-9. 2013
  6. doi request reprint Multiple epithelioid Spitz nevi or tumors with loss of BAP1 expression: a clue to a hereditary tumor syndrome
    Klaus J Busam
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
    JAMA Dermatol 149:335-9. 2013
  7. doi request reprint Tumours associated with BAP1 mutations
    Rajmohan Murali
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Pathology 45:116-26. 2013
  8. doi request reprint Clinicopathologic features of early lesions of primary cutaneous follicle center lymphoma, diffuse type: implications for early diagnosis and treatment
    Andrea Gulia
    Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria
    J Am Acad Dermatol 65:991-1000. 2011
  9. doi request reprint Clinicopathologic and molecular features in cutaneous extranodal natural killer-/T-cell lymphoma, nasal type, with aggressive and indolent course
    Isabella Fried
    Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria
    J Am Acad Dermatol 70:716-23. 2014
  10. doi request reprint Cutaneous manifestations of blastic plasmacytoid dendritic cell neoplasm-morphologic and phenotypic variability in a series of 33 patients
    Carlo Cota
    Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria
    Am J Surg Pathol 34:75-87. 2010

Collaborators

Detail Information

Publications15

  1. doi request reprint [Morphological and genetic aspects of Spitz tumors]
    T Wiesner
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 415 E 68th Street, 10065, New York, NY, USA
    Pathologe 36:37-43, 45. 2015
    ..Spitzoid melanocytic neoplasms (i.e. Spitz nevi, atypical Spitz tumors and spitzoid melanoma) are a clinical, histopathological and molecular genetic heterogeneous group of melanocytic skin tumors...
  2. pmc Germline mutations in BAP1 predispose to melanocytic tumors
    Thomas Wiesner
    Department of Dermatology, Medical University of Graz, Graz, Austria
    Nat Genet 43:1018-21. 2011
    ..These findings suggest that loss of BAP1 is associated with a clinically and morphologically distinct type of melanocytic neoplasm...
  3. doi request reprint Clinical and pathologic findings of Spitz nevi and atypical Spitz tumors with ALK fusions
    Klaus J Busam
    Department of Pathology Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY Dermatopathologie Friedrichshafen, Friedrichshafen, Germany Department of Dermatology, Medical University Graz, Graz, Austria
    Am J Surg Pathol 38:925-33. 2014
    ....
  4. pmc A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression
    Thomas Wiesner
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 36:818-30. 2012
    ..Future studies are necessary to determine whether this subset has a predictable clinical behavior...
  5. doi request reprint Combined BRAF(V600E)-positive melanocytic lesions with large epithelioid cells lacking BAP1 expression and conventional nevomelanocytes
    Klaus J Busam
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 37:193-9. 2013
    ..The lesions described herein may represent a peculiar combined melanocytic nevus variant. However, longer follow-up and more studies are needed to determine the biological potential of the BAP1-negative melanocyte proliferations...
  6. doi request reprint Multiple epithelioid Spitz nevi or tumors with loss of BAP1 expression: a clue to a hereditary tumor syndrome
    Klaus J Busam
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
    JAMA Dermatol 149:335-9. 2013
    ..The large melanocytes are immunohistochemically characterized by loss of nuclear labeling for BAP1...
  7. doi request reprint Tumours associated with BAP1 mutations
    Rajmohan Murali
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Pathology 45:116-26. 2013
    ....
  8. doi request reprint Clinicopathologic features of early lesions of primary cutaneous follicle center lymphoma, diffuse type: implications for early diagnosis and treatment
    Andrea Gulia
    Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria
    J Am Acad Dermatol 65:991-1000. 2011
    ..Data on early lesions of primary cutaneous follicle center lymphoma (PCFCL), diffuse type are very limited...
  9. doi request reprint Clinicopathologic and molecular features in cutaneous extranodal natural killer-/T-cell lymphoma, nasal type, with aggressive and indolent course
    Isabella Fried
    Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria
    J Am Acad Dermatol 70:716-23. 2014
    ..Extranodal natural killer-/T-cell lymphoma, nasal type (ENKTCL-NT) is a highly aggressive lymphoma and prognosis is usually poor. The genetic background of primary cutaneous cases is poorly understood...
  10. doi request reprint Cutaneous manifestations of blastic plasmacytoid dendritic cell neoplasm-morphologic and phenotypic variability in a series of 33 patients
    Carlo Cota
    Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria
    Am J Surg Pathol 34:75-87. 2010
    ..These atypical variants should be recognized to make an early diagnosis and to manage properly patients with this aggressive hematological disorder...
  11. pmc Ambiguous melanocytic tumors with loss of 3p21
    Iwei Yeh
    Departments of Dermatology Pathology, University of California, San Francisco Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
    Am J Surg Pathol 38:1088-95. 2014
    ..We describe BAP1 loss in a blue nevus-like melanoma and further expand the histopathologic spectrum of spitzoid melanocytic neoplasms with BAP1 loss. ..
  12. doi request reprint Alterations of the cell-cycle inhibitors p27(KIP1) and p16(INK4a) are frequent in blastic plasmacytoid dendritic cell neoplasms
    Thomas Wiesner
    Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria
    J Invest Dermatol 130:1152-7. 2010
    ..The elucidation of the affected pathways may guide the development of new treatments specifically designed for this aggressive disease entity...
  13. doi request reprint Lupus erythematosus with exclusive involvement of the acrosyringia
    Isabella Fried
    Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Austria
    J Cutan Pathol 37:91-3. 2010
    ..The histopathologic features represent a pitfall in the diagnosis and can be correctly interpreted only upon correlation with clinical data...
  14. pmc Kinase fusions are frequent in Spitz tumours and spitzoid melanomas
    Thomas Wiesner
    1 Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 415 E 68th Street, New York, New York 10065, USA 2 Department of Dermatology and Venereology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria 3
    Nat Commun 5:3116. 2014
    ..In summary, kinase fusions account for the majority of oncogenic aberrations in spitzoid neoplasms and may serve as therapeutic targets for metastatic spitzoid melanomas. ..
  15. doi request reprint Two-dimensional visualization of multicolor FISH-generated data as a helpful tool for the analysis and understanding of cytogenetic and chromosomal alterations in melanocytic lesions
    Katrin Kerl
    Department of Dermatology, Zurich University Hospital, Zurich, Switzerland
    Am J Dermatopathol 35:151-8. 2013
    ..These two graphic tools provide information additional to the currently used numerical algorithms and thus facilitate the recognition and compensation of inherent errors that occur with the numerical method...