Martin R Weiser

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi Clinical examination following preoperative chemoradiation for rectal cancer is not a reliable surrogate end point
    Jose G Guillem
    Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Room C 1077, New York, NY 10021, USA
    J Clin Oncol 23:3475-9. 2005
  2. ncbi Predictive clinicopathologic factors for limited response of T3 rectal cancer to combined modality therapy
    Anne Y Lin
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Colorectal Dis 23:243-9. 2008
  3. ncbi Pathologic stage is most prognostic of disease-free survival in locally advanced rectal cancer patients after preoperative chemoradiation
    Hak Mien Quah
    Department of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer 113:57-64. 2008
  4. ncbi Effects of obesity in rectal cancer surgery
    Hueylan Chern
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Am Coll Surg 211:55-60. 2010
  5. ncbi Immunohistochemical staining for DNA mismatch repair proteins in intestinal tract carcinoma: how reliable are biopsy samples?
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 35:447-54. 2011
  6. ncbi Sphincter preservation in low rectal cancer is facilitated by preoperative chemoradiation and intersphincteric dissection
    Martin R Weiser
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg 249:236-42. 2009
  7. ncbi Predicting survival after curative colectomy for cancer: individualizing colon cancer staging
    Martin R Weiser
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Clin Oncol 29:4796-802. 2011
  8. ncbi Individualized prediction of colon cancer recurrence using a nomogram
    Martin R Weiser
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    J Clin Oncol 26:380-5. 2008
  9. ncbi Surgical salvage of recurrent rectal cancer after transanal excision
    Martin R Weiser
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 48:1169-75. 2005
  10. ncbi Squamous-cell carcinoma of the anal canal: predictors of treatment outcome
    Ramin Roohipour
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 51:147-53. 2008

Detail Information

Publications74

  1. ncbi Clinical examination following preoperative chemoradiation for rectal cancer is not a reliable surrogate end point
    Jose G Guillem
    Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Room C 1077, New York, NY 10021, USA
    J Clin Oncol 23:3475-9. 2005
    ..However, because the accuracy of this approach has not been established, we conducted a prospective analysis to determine the operating surgeon's ability to assess response using DRE...
  2. ncbi Predictive clinicopathologic factors for limited response of T3 rectal cancer to combined modality therapy
    Anne Y Lin
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Colorectal Dis 23:243-9. 2008
    ..The aim of this study was to identify pretreatment factors associated with poor tumor response to neoadjuvant chemoradiation...
  3. ncbi Pathologic stage is most prognostic of disease-free survival in locally advanced rectal cancer patients after preoperative chemoradiation
    Hak Mien Quah
    Department of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer 113:57-64. 2008
    ....
  4. ncbi Effects of obesity in rectal cancer surgery
    Hueylan Chern
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Am Coll Surg 211:55-60. 2010
    ..In this study, we evaluate whether higher body mass index (BMI) compromises surgical resection in patients with locally advanced, mid-to-low rectal cancer after neoadjuvant therapy, adversely affecting long-term oncologic outcomes...
  5. ncbi Immunohistochemical staining for DNA mismatch repair proteins in intestinal tract carcinoma: how reliable are biopsy samples?
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 35:447-54. 2011
    ..However, whether biopsy samples can be reliably used for mismatch repair protein detection remains to be determined...
  6. ncbi Sphincter preservation in low rectal cancer is facilitated by preoperative chemoradiation and intersphincteric dissection
    Martin R Weiser
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg 249:236-42. 2009
    ....
  7. ncbi Predicting survival after curative colectomy for cancer: individualizing colon cancer staging
    Martin R Weiser
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Clin Oncol 29:4796-802. 2011
    ..The purpose of this study was to extend the seventh edition of the AJCC staging system for colon cancer to incorporate additional information available from tumor registries, thereby improving prognostic accuracy...
  8. ncbi Individualized prediction of colon cancer recurrence using a nomogram
    Martin R Weiser
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    J Clin Oncol 26:380-5. 2008
    ..Although easy to implement, there remains significant heterogeneity within each stage grouping. In the era of multimodality treatment, a more refined tool is needed to predict recurrence...
  9. ncbi Surgical salvage of recurrent rectal cancer after transanal excision
    Martin R Weiser
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 48:1169-75. 2005
    ..This study examines surgical salvage of locally recurrent rectal cancer following transanal excision of early tumors...
  10. ncbi Squamous-cell carcinoma of the anal canal: predictors of treatment outcome
    Ramin Roohipour
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 51:147-53. 2008
    ..The incidence of anal canal squamous-cell carcinoma is increasing. Limited data exist on predictors of treatment failure. This study was designed to identify predictors for relapse/persistence after first-line therapy...
  11. ncbi Identification of patients with high-risk stage II colon cancer for adjuvant therapy
    Hak Mien Quah
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Dis Colon Rectum 51:503-7. 2008
    ..The purpose of this study was to assess the prognostic significance of commonly reported clinicopathologic features of Stage II colon cancer to identify high-risk patients...
  12. ncbi Evaluation of ¹⁸F-FDG-PET for early detection of suboptimal response of rectal cancer to preoperative chemoradiotherapy: a prospective analysis
    Tobias Leibold
    Department of Surgery Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:2783-9. 2011
    ..We prospectively evaluated tumor response with (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) early in the course of preoperative CRT...
  13. ncbi Squamous-cell carcinoma of the rectum: a rare but curable tumor
    Caio S R Nahas
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Dis Colon Rectum 50:1393-400. 2007
    ..This study was designed to evaluate one institution's experience with treatment outcomes for rectal squamous-cell carcinoma...
  14. ncbi Carcinoid of the rectum risk stratification (CaRRs): a strategy for preoperative outcome assessment
    Bridget N Fahy
    Department of Surgery, Division of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Ann Surg Oncol 14:1735-43. 2007
    ..Predicting rectal carcinoid behavior based exclusively on tumor size is imprecise. We sought to identify factors associated with outcome and incorporate them into a pre-operative risk stratification scheme...
  15. ncbi Rate of residual disease after complete endoscopic resection of malignant colonic polyp
    Jean M Butte
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Dis Colon Rectum 55:122-7. 2012
    ..Following polypectomy, colectomy is performed selectively to ensure complete clearance of neoplasia...
  16. ncbi Complications after preoperative combined modality therapy and radical resection of locally advanced rectal cancer: a 14-year experience from a specialty service
    David B Chessin
    Colorectal Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
    J Am Coll Surg 200:876-82; discussion 882-4. 2005
    ....
  17. ncbi A predictive model for lymph node yield in colon cancer resection specimens
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Ann Surg 253:318-22. 2011
    ..To develop a predictive model of lymph node yield in a series of colon cancer resection specimens with detailed anatomic and surgical technique data...
  18. ncbi Challenging the feasibility and clinical significance of current guidelines on lymph node examination in rectal cancer in the era of neoadjuvant therapy
    Anand Govindarajan
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Clin Oncol 29:4568-73. 2011
    ..We sought to examine the feasibility and clinical significance of current guidelines on nodal assessment in patients with rectal cancer (RC) treated with neoadjuvant radiation...
  19. ncbi Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix
    Laura H Tang
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 32:1429-43. 2008
    ..Surgical management with right hemicolectomy is recommended after appendectomy for most cases, particularly those with an adenocarcinoma component (groups B and C)...
  20. ncbi Can differences in bowel function after surgery for rectal cancer be identified by the European Organization for Research and Treatment of Cancer quality of life instrument?
    Heather B Neuman
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, New York 10021, USA
    Ann Surg Oncol 14:1727-34. 2007
    ....
  21. ncbi MET activation mediates resistance to lapatinib inhibition of HER2-amplified gastric cancer cells
    Chin Tung Chen
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Mol Cancer Ther 11:660-9. 2012
    ..Development of inhibitors targeting multiple receptors or common downstream signaling proteins merits further investigation...
  22. ncbi Pulmonary recurrence predominates after combined modality therapy for rectal cancer: an original retrospective study
    Peirong Ding
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:111-6. 2012
    ..To characterize patterns of recurrence in locally advanced rectal cancer treated with combined modality therapy (CMT): neoadjuvant chemoradiation + total mesorectal excision + adjuvant chemotherapy...
  23. ncbi Recurrence rates and prognostic factors in ypN0 rectal cancer after neoadjuvant chemoradiation and total mesorectal excision
    Anand Govindarajan
    Department of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:3666-72. 2011
    ..Patients with pathologically node-negative tumors have an improved prognosis, but recurrence patterns and independent prognostic factors in these patients have been incompletely characterized...
  24. ncbi Synchronous hepatic metastases from colon cancer: changing treatment strategies and results of surgical intervention
    Bridget N Fahy
    Department of Surgery, The Methodist Hospital, Houston, TX 77030, USA
    Ann Surg Oncol 16:361-70. 2009
    ..A multidisciplinary treatment approach which combines both medical and surgical modalities may be associated with improved survival...
  25. ncbi Long-term survival after transanal excision of T1 rectal cancer
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Dis Colon Rectum 52:577-82. 2009
    ..However, the impact of transanal excision on cancer mortality has not been adequately studied. The purpose of this study was to compare oncologic outcomes of transanal excision with those of radical resection...
  26. ncbi Clinical and pathologic factors that predict lymph node yield from surgical specimens in colorectal cancer: a population-based study
    Joanne F Chou
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer 116:2560-70. 2010
    ..However, heterogeneity in LN harvest exists. The objective of this study was to investigate the clinicopathologic factors that influence LN yield...
  27. ncbi Significance of acellular mucin pools in rectal carcinoma after neoadjuvant chemoradiotherapy
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 35:127-34. 2011
    ....
  28. ncbi Limitations of early rectal cancer nodal staging may explain failure after local excision
    Ron G Landmann
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Dis Colon Rectum 50:1520-5. 2007
    ..The limitations of endorectal ultrasound in accurately staging nodal disease in early rectal lesions may, in part, explain the relatively high recurrence rates seen after local excision...
  29. ncbi Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer
    Jose G Guillem
    Department of Surgery Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg 241:829-36; discussion 836-8. 2005
    ....
  30. ncbi Feasibility of ex vivo FDG PET of the colon
    Marc J Gollub
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10023, USA
    Radiology 252:232-9. 2009
    ....
  31. ncbi Treatment for patients with rectal cancer and a clinical complete response to neoadjuvant therapy: a decision analysis
    Heather B Neuman
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Dis Colon Rectum 52:863-71. 2009
    ..Therefore, the objective was to develop a decision-analytic model to evaluate the relative benefits of surgery vs. observation in rectal cancer patients who achieve clinical complete response after neoadjuvant chemoradiation...
  32. ncbi Sacral resection for recurrent rectal cancer: analysis of morbidity and treatment results
    Genevieve B Melton
    Division of Colorectal Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 49:1099-107. 2006
    ..This procedure has a low cure rate but may provide local disease control with acceptable morbidity...
  33. ncbi T1 adenocarcinoma of the rectum: transanal excision or radical surgery?
    David J Bentrem
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Surg 242:472-7; discussion 477-9. 2005
    ..We performed a retrospective evaluation of patients with T1 rectal cancers treated by either transanal excision or radical resection at our institution to assess patient selection, cancer recurrence, and survival...
  34. ncbi Operative salvage for locoregional recurrent colon cancer after curative resection: an analysis of 100 cases
    Wilbur B Bowne
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 48:897-909. 2005
    ..Complete resection is critical to long-term survival and is associated with a single site of recurrence, perianastomotic disease, low presalvage carcinembryonic antigen level, and absence of distant disease...
  35. ncbi Whole-mount pathologic analysis of rectal cancer following neoadjuvant therapy: implications of margin status on long-term oncologic outcome
    James J Mezhir
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:274-9. 2012
    ..We set out to determine the long-term oncologic impact of resection margins in patients with locally advanced rectal cancer using a comprehensive pathologic whole-mount section analysis...
  36. ncbi Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition
    Thomas Bachleitner-Hofmann
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Clin Cancer Res 17:122-33. 2011
    ..MET, a tyrosine kinase that is constitutively active in tumor cells with MET oncogene amplification, has recently been identified as another HSP-90 client...
  37. ncbi The role of abdominoperineal resection as surgical therapy for anorectal melanoma
    Jen Jen Yeh
    Memorial-Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Surg 244:1012-7. 2006
    ..Therefore, LE of the primary tumor is recommended when technically feasible. The presence of PNI is an important prognostic factor and should be considered in future clinical trials...
  38. ncbi MET expression and amplification in patients with localized gastric cancer
    Yelena Y Janjigian
    Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Medical College of Cornell University, New York, NY 10065, USA
    Cancer Epidemiol Biomarkers Prev 20:1021-7. 2011
    ..MET, the receptor for hepatocyte growth factor, has been proposed as a therapeutic target in gastric cancer. This study assessed the incidence of MET expression and gene amplification in tumors of Western patients with gastric cancer...
  39. ncbi Positron emission tomography detection of distant metastatic or synchronous disease in patients with locally advanced rectal cancer receiving preoperative chemoradiation
    Caio S R Nahas
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 15:704-11. 2008
    ....
  40. ncbi Oncologic outcomes of salvage surgery for epidermoid carcinoma of the anus initially managed with combined modality therapy
    Robert P Akbari
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
    Dis Colon Rectum 47:1136-44. 2004
    ..persistence) after chemoradiation (when salvage is potentially curative), absence of nodal disease at salvage, and negative margins. Salvage inguinal lymph node dissection after failed chemoradiation therapy also is potentially curative...
  41. ncbi Patterns of morphologic alteration in residual rectal carcinoma following preoperative chemoradiation and their association with long-term outcome
    Jinru Shia
    Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Am J Surg Pathol 28:215-23. 2004
    ..Our results demonstrate distinct morphologic features in treated rectal carcinomas that are prognostically relevant...
  42. ncbi Folate receptor-α expression in resectable hepatic colorectal cancer metastases: patterns and significance
    Michael D'Angelica
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 24:1221-8. 2011
    ..The prognostic value of FRα expression and the utility of FRα-targeted therapies in stage-IV colorectal cancer patients deserve further exploration...
  43. ncbi Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 33:1639-45. 2009
    ..Such a cost-effective approach carries significant implication, as immunohistochemistry is being widely used as first-line screening for HNPCC...
  44. ncbi HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells
    Thomas Bachleitner-Hofmann
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Mol Cancer Ther 7:3499-508. 2008
    ....
  45. ncbi Is nonsmall cell type high-grade neuroendocrine carcinoma of the tubular gastrointestinal tract a distinct disease entity?
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:719-31. 2008
    ..These tumors are clinically aggressive. Prospective studies using defined diagnostic criteria are needed to determine their biologic characteristics and optimal management...
  46. ncbi Nodal staging score: a tool to assess adequate staging of node-negative colon cancer
    Mithat Gonen
    Memorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, 1275 York Ave, Box 44, New York, NY 10065, USA
    J Clin Oncol 27:6166-71. 2009
    ..We sought to refine this definition by quantifying the likelihood that a pathologically node-negative patient has, indeed, no positive nodes...
  47. ncbi Quality of life and symptom control after stent placement or surgical palliation of malignant colorectal obstruction
    Satish Nagula
    Department of Medicine, Gastroenterology, and Nutrition Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Am Coll Surg 210:45-53. 2010
    ..Self-expanding metal stents have emerged as an alternative for palliation of malignant LBO. However, there are few long-term studies documenting the effect of surgical palliation or colonic stents on symptoms or quality of life (QoL)...
  48. ncbi Early postoperative intraperitoneal chemotherapy following cytoreductive surgery for appendiceal mucinous neoplasms with isolated peritoneal metastasis
    Patrick L Wagner
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Dis Colon Rectum 55:407-15. 2012
    ..At our institution, patients undergoing complete cytoreduction in this setting typically receive multiple cycles of early postoperative intraperitoneal chemotherapy...
  49. ncbi Novel xenograft model expressing human hepatocyte growth factor shows ligand-dependent growth of c-Met-expressing tumors
    Todd D Francone
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Mol Cancer Ther 6:1460-6. 2007
    ..This novel xenograft model is ideal for investigating c-Met/HGF-dependent human tumor progression and for evaluating c-Met targeted therapy...
  50. ncbi HGF rescues colorectal cancer cells from EGFR inhibition via MET activation
    David Liska
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Clin Cancer Res 17:472-82. 2011
    ..Here, we investigate hepatocyte growth factor (HGF)-dependent mesenchymal-epithelial transition factor (MET) activation as a mediator of cetuximab resistance through signal diversification in CRC cell lines...
  51. ncbi c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases
    Zhao Shi Zeng
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Cancer Lett 265:258-69. 2008
    ..c-Met gene amplification is linked to metastatic progression, and is a viable target for a significant subset of advanced CRC...
  52. ncbi Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy
    James D Smith
    Departments of Surgery Radiation Oncology Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY
    Ann Surg 256:965-72. 2012
    ....
  53. ncbi Patterns of failure in patients with early onset (synchronous) resectable liver metastases from rectal cancer
    Jean M Butte
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
    Cancer 118:5414-23. 2012
    ..In this study, the authors examined recurrence patterns and survival after resection of SLMRC...
  54. ncbi Carcinoid of the rectum risk stratification (CaRRS): a strategy for preoperative outcome assessment
    Bridget N Fahy
    Department of Surgery, Division of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Ann Surg Oncol 14:396-404. 2007
    ..Predicting rectal carcinoid behavior exclusively on the basis of tumor size is imprecise. We sought to identify factors associated with outcome and incorporate them into a preoperative risk stratification scheme...
  55. ncbi The development of a validated instrument to evaluate bowel function after sphincter-preserving surgery for rectal cancer
    Larissa K Temple
    Department of Surgery, Division of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 48:1353-65. 2005
    ..Therefore, the purpose of this study was to develop an instrument to evaluate bowel function after sphincter-preserving surgery...
  56. ncbi Differential expression of alpha-methylacyl-coenzyme A racemase in colorectal carcinoma bears clinical and pathologic significance
    Anne Lin
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Hum Pathol 38:850-6. 2007
    ..Further investigation on interaction between AMACR and other known colorectal cancer development pathways may provide new insights on colorectal carcinogenesis...
  57. ncbi Response to Neoadjuvant Therapy in Patients With Early Age-of-Onset Rectal Cancer
    Emily Steinhagen
    1 Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 2 Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 3 Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York
    Dis Colon Rectum 56:58-63. 2013
    ..The response to neoadjuvant treatment in patients ≤50 years of age is not known. Factors affecting the response to neoadjuvant therapy in this age group have not been evaluated...
  58. ncbi Prospective immunohistochemical analysis of primary colorectal cancers for loss of mismatch repair protein expression
    Steven A Lee-Kong
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Clin Colorectal Cancer 9:255-9. 2010
    ..We examined the value of routine immunohistochemistry (IHC) for MMR proteins in patients with colorectal cancer (CRC) undergoing resection at a single institution...
  59. ncbi Contemporary imaging for colorectal cancer
    Carl R Schmidt
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Surg Oncol Clin N Am 16:369-88. 2007
    ..Postoperative imaging enhances identification of recurrent disease that might be amenable to salvage surgery...
  60. ncbi Randomized clinical trials in rectal and anal cancers
    Jason Park
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Surg Oncol Clin N Am 19:205-23. 2010
    ..The article discusses the major RCTs and relevant findings that have impacted clinical management most and includes most but not all RCTs on therapy for rectal cancer published during this period...
  61. ncbi Factors associated with sphincter-preserving surgery for rectal cancer at national comprehensive cancer network centers
    Larissa K Temple
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 250:260-7. 2009
    ..To determine rate and predictors of sphincter-preserving surgery (SPS) for rectal cancer patients treated at specialty institutions...
  62. ncbi Increased endocrine cells in treated rectal adenocarcinomas: a possible reflection of endocrine differentiation in tumor cells induced by chemotherapy and radiotherapy
    Jinru Shia
    Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Am J Surg Pathol 26:863-72. 2002
    ..The possible mechanism for the increased endocrine cells in treated rectal adenocarcinomas may be related to induction of endocrine differentiation in tumor cells by cytotoxic insult...
  63. ncbi Immunohistochemical expression of folate receptor alpha in colorectal carcinoma: patterns and biological significance
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Hum Pathol 39:498-505. 2008
    ..The significance of such an association as well as the prognostic value of FRalpha expression deserves further exploration...
  64. ncbi Accuracy of endorectal ultrasound for measurement of the closest predicted radial mesorectal margin for rectal cancer
    P Terry Phang
    St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    Dis Colon Rectum 55:59-64. 2012
    ..Endorectal ultrasound is also used to assess the clinical stage of the cancer that will determine the recommendation for neoadjuvant chemoradiation, but it has not been used to assess the closest predicted radial margin...
  65. ncbi Immunoblot analysis of c-Met expression in human colorectal cancer: overexpression is associated with advanced stage cancer
    Zhaoshi Zeng
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Exp Metastasis 21:409-17. 2004
    ..C-Met protein is expressed at levels significantly higher than adjacent mucosa in most primary adenocarcinomas of the colon. Our results support an important role for c-Met in human CRC progression and metastasis...
  66. ncbi Prevalence of perianal intraepithelial neoplasia in HIV-infected patients referred for high-resolution anoscopy
    Caio S R Nahas
    Colorectal Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
    Dis Colon Rectum 49:1581-6. 2006
    ..Our data suggest that anal canal neoplasia often is accompanied by perianal disease and illustrates the need for biopsy of any suspicious perianal lesions...
  67. ncbi Whither TNM?
    Mithat Gonen
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Semin Oncol 37:27-30. 2010
    ..We recommend that parsimony should be considered to counterbalance the instinct to increase the number of categories in future revisions of staging systems such as TNM...
  68. ncbi Response of stage IV anal mucosal melanoma to chemotherapy
    Jen Jen Yeh
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
    Lancet Oncol 6:438-9. 2005
  69. ncbi Combined CT colonography and 18F-FDG PET of colon polyps: potential technique for selective detection of cancer and precancerous lesions
    Marc J Gollub
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Rm C276F, New York, NY 10021, USA
    AJR Am J Roentgenol 188:130-8. 2007
    ..The purpose of this study was to determine the feasibility of imaging the colon with fused CT colonography (CTC) and 18F-FDG PET and to correlate the findings with the histologic features of polyps...
  70. ncbi L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition
    Cristina R Antonescu
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Int J Cancer 121:257-64. 2007
    ..These results suggest that a subset of anal melanomas show activating KIT mutations, which are susceptible for therapy with specific kinase inhibitors...
  71. ncbi An update on laparoscopic resection for rectal cancer
    David Row
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Cancer Control 17:16-24. 2010
    ..The available literature focusing on laparoscopic resection for rectal cancer has been predominantly retrospective in nature, with a limited number of prospective studies...
  72. ncbi Randomized clinical trials in colon cancer
    Heather B Neuman
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, H1206, New York, NY 10065, USA
    Surg Oncol Clin N Am 19:183-204. 2010
    ..We review those randomized controlled trials that have most impacted the clinical management of patients with colon cancer in 2009...
  73. ncbi Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome
    Udai S Kammula
    Surgery Branch, National Cancer Institute, Bethesda, MD, USA
    Cancer Lett 248:219-28. 2007
    ..We hypothesize that over-expression of the c-Met receptor and its ligand, hepatocyte growth factor (HGF) in the tumor microenvironment is associated with tumor progression and metastases...
  74. ncbi Lymph node metastasis in T1 adenocarcinoma of the colon and rectum
    Satoshi Okabe
    Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan
    J Gastrointest Surg 8:1032-9; discussion 1039-40. 2004
    ..In early colorectal cancers, tumor morphology is the strongest clinical predictor of metastatic behavior...