Liang Wang

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi request reprint Assessment of biologic aggressiveness of prostate cancer: correlation of MR signal intensity with Gleason grade after radical prostatectomy
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Rm C 278, New York, NY 10021, USA
    Radiology 246:168-76. 2008
  2. doi request reprint Post-processing of dynamic gadolinium-enhanced magnetic resonance imaging exams of the liver: explanation and potential clinical applications for color-coded qualitative and quantitative analysis
    L Wang
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Acta Radiol 49:6-18. 2008
  3. ncbi request reprint Prediction of seminal vesicle invasion in prostate cancer: incremental value of adding endorectal MR imaging to the Kattan nomogram
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 242:182-8. 2007
  4. ncbi request reprint Prediction of organ-confined prostate cancer: incremental value of MR imaging and MR spectroscopic imaging to staging nomograms
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 238:597-603. 2006
  5. ncbi request reprint Prostate cancer: incremental value of endorectal MR imaging findings for prediction of extracapsular extension
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Radiology 232:133-9. 2004
  6. pmc An exploratory study of endorectal magnetic resonance imaging and spectroscopy of the prostate as preoperative predictive biomarkers of biochemical relapse after radical prostatectomy
    Kristen L Zakian
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Urol 184:2320-7. 2010
  7. ncbi request reprint Incremental value of multiplanar cross-referencing for prostate cancer staging with endorectal MRI
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Rm C 278, New York, NY 10021, USA
    AJR Am J Roentgenol 188:99-104. 2007
  8. ncbi request reprint Combined endorectal and phased-array MRI in the prediction of pelvic lymph node metastasis in prostate cancer
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Rm C 278, New York, NY 10021, USA
    AJR Am J Roentgenol 186:743-8. 2006
  9. ncbi request reprint Prostate cancer: detection of extracapsular extension by genitourinary and general body radiologists at MR imaging
    Michael Mullerad
    Department of Urology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Radiology 232:140-6. 2004
  10. ncbi request reprint Shape-constraint region growing for delineation of hepatic metastases on contrast-enhanced computed tomograph scans
    Binsheng Zhao
    Department of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Invest Radiol 41:753-62. 2006

Detail Information

Publications61

  1. ncbi request reprint Assessment of biologic aggressiveness of prostate cancer: correlation of MR signal intensity with Gleason grade after radical prostatectomy
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Rm C 278, New York, NY 10021, USA
    Radiology 246:168-76. 2008
    ....
  2. doi request reprint Post-processing of dynamic gadolinium-enhanced magnetic resonance imaging exams of the liver: explanation and potential clinical applications for color-coded qualitative and quantitative analysis
    L Wang
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Acta Radiol 49:6-18. 2008
    ..In addition, these tools may facilitate the diagnostic workup of disease for detection, characterization, staging, and monitoring of antitumor therapy, and hold incremental value to the widely used tumor response criteria...
  3. ncbi request reprint Prediction of seminal vesicle invasion in prostate cancer: incremental value of adding endorectal MR imaging to the Kattan nomogram
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 242:182-8. 2007
    ..To retrospectively determine whether endorectal magnetic resonance (MR) imaging findings contribute incremental value to the Kattan nomogram for predicting seminal vesicle invasion (SVI) in patients with prostate cancer...
  4. ncbi request reprint Prediction of organ-confined prostate cancer: incremental value of MR imaging and MR spectroscopic imaging to staging nomograms
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 238:597-603. 2006
    ..To assess retrospectively the incremental value of endorectal coil magnetic resonance (MR) imaging and combined endorectal MR imaging-MR spectroscopic imaging to the staging nomograms for predicting organ-confined prostate cancer (OCPC)...
  5. ncbi request reprint Prostate cancer: incremental value of endorectal MR imaging findings for prediction of extracapsular extension
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Radiology 232:133-9. 2004
    ..To assess the incremental value of endorectal magnetic resonance (MR) imaging findings in addition to clinical variables for prediction of extracapsular extension (ECE) in patients with prostate cancer...
  6. pmc An exploratory study of endorectal magnetic resonance imaging and spectroscopy of the prostate as preoperative predictive biomarkers of biochemical relapse after radical prostatectomy
    Kristen L Zakian
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Urol 184:2320-7. 2010
    ..We determined whether pretreatment endorectal magnetic resonance imaging/magnetic resonance spectroscopic imaging predicts biochemical recurrence after radical prostatectomy...
  7. ncbi request reprint Incremental value of multiplanar cross-referencing for prostate cancer staging with endorectal MRI
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Rm C 278, New York, NY 10021, USA
    AJR Am J Roentgenol 188:99-104. 2007
    ..The purpose of this study was to assess whether use of the PACS cross-referencing tool in 3D MRI improves tumor staging of prostate cancer when pathologic findings are used as the reference standard...
  8. ncbi request reprint Combined endorectal and phased-array MRI in the prediction of pelvic lymph node metastasis in prostate cancer
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Rm C 278, New York, NY 10021, USA
    AJR Am J Roentgenol 186:743-8. 2006
    ....
  9. ncbi request reprint Prostate cancer: detection of extracapsular extension by genitourinary and general body radiologists at MR imaging
    Michael Mullerad
    Department of Urology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Radiology 232:140-6. 2004
    ..To determine whether predictive value of endorectal magnetic resonance (MR) imaging findings in detection of prostate cancer extracapsular extension (ECE) is significantly affected by the reader's subspecialty experience...
  10. ncbi request reprint Shape-constraint region growing for delineation of hepatic metastases on contrast-enhanced computed tomograph scans
    Binsheng Zhao
    Department of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Invest Radiol 41:753-62. 2006
    ....
  11. ncbi request reprint Significance of peritumoral vascularity on CT in evaluation of renal cortical tumor
    Jingbo Zhang
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Comput Assist Tomogr 31:717-23. 2007
    ..To investigate whether the presence and degree of peritumoral vascularity may provide any diagnostic information regarding the histological subtypes of renal tumors...
  12. pmc Predicting post-external beam radiation therapy PSA relapse of prostate cancer using pretreatment MRI
    Michael H Fuchsjäger
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Int J Radiat Oncol Biol Phys 78:743-50. 2010
    ..To investigate whether pretreatment endorectal magnetic resonance imaging (MRI) findings can predict biochemical relapse in patients with clinically localized prostate cancer treated with external beam radiation therapy (EBRT)...
  13. doi request reprint Are histopathological features of prostate cancer lesions associated with identification of extracapsular extension on magnetic resonance imaging?
    Liang Wang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    BJU Int 106:1303-8. 2010
    ..To assess the effect of histopathological lesion characteristics on the sensitivity of magnetic resonance imaging (MRI) for per-lesion identification of extracapsular extension (ECE) of prostate cancer...
  14. ncbi request reprint Solid renal cortical tumors: differentiation with CT
    Jingbo Zhang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Room C278D, New York, NY 10021, USA
    Radiology 244:494-504. 2007
    ..To retrospectively determine if solid renal cortical tumors can be differentiated on computed tomographic (CT) images on the basis of their morphologic features and enhancement patterns...
  15. doi request reprint Renal masses: characterization with diffusion-weighted MR imaging--a preliminary experience
    Jingbo Zhang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, RM C278D, New York, NY 10021, USA
    Radiology 247:458-64. 2008
    ..To retrospectively assess the usefulness of apparent diffusion coefficients (ADCs) for characterizing renal masses (ie, viable solid tumors, necrotic or cystic tumor areas, and benign cysts)...
  16. ncbi request reprint Marker-controlled watershed for lymphoma segmentation in sequential CT images
    Jiayong Yan
    Medical Physics Department, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Med Phys 33:2452-60. 2006
    ..7 and 3.7 mm. Preliminary results have shown the potential of this computer algorithm to allow reliable segmentation and quantification of lymphomas on sequential CT images...
  17. ncbi request reprint The role of preoperative endorectal magnetic resonance imaging in the decision regarding whether to preserve or resect neurovascular bundles during radical retropubic prostatectomy
    Hedvig Hricak
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 100:2655-63. 2004
    ..In the current study, the authors determined the incremental value of endorectal magnetic resonance imaging (eMRI) in making this decision...
  18. pmc Perihepatic lymph node assessment in patients undergoing partial hepatectomy for malignancy
    Stephen R Grobmyer
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Surg 244:260-4. 2006
    ..To assess the value of preoperative imaging studies and the intraoperative assessment of perihepatic lymph nodes in patients undergoing partial hepatectomy for malignancy...
  19. ncbi request reprint Liver segmentation for CT images using GVF snake
    Fan Liu
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Med Phys 32:3699-706. 2005
    ..The difference ratio, which is defined as the percentage ratio of mismatching volume between the computer and the radiologist's results, ranged from 2.9% to 7.6% with a median value of 5.3%...
  20. doi request reprint Magnetic resonance imaging in the prediction of biochemical recurrence of prostate cancer after radical prostatectomy
    Michael H Fuchsjäger
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    BJU Int 104:315-20. 2009
    ..To investigate whether magnetic resonance imaging (MRI) findings, when converted into a scoring system, can predict the biochemical recurrence of prostate cancer after radical prostatectomy (RP)...
  21. doi request reprint Distribution of renal tumor growth rates determined by using serial volumetric CT measurements
    Jingbo Zhang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 250:137-44. 2009
    ..To retrospectively determine the distribution of growth rates across different sizes and subtypes of renal cortical tumors by assessing tumor volume and maximum tumor diameter at serial volumetric computed tomographic (CT) examinations...
  22. pmc Focal treatment or observation of prostate cancer: pretreatment accuracy of transrectal ultrasound biopsy and T2-weighted MRI
    Lucas Nogueira
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Urology 75:472-7. 2010
    ....
  23. ncbi request reprint Response assessment classification in patients with advanced renal cell carcinoma treated on clinical trials
    Lawrence H Schwartz
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 98:1611-9. 2003
    ....
  24. ncbi request reprint Pulmonary metastases: effect of CT section thickness on measurement--initial experience
    Binsheng Zhao
    Department of Radiology and Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 234:934-9. 2005
    ..To assess the effect of commonly used computed tomographic (CT) section thicknesses on metastatic tumor measurements calculated with unidimensional, bidimensional, area, and volumetric methods...
  25. ncbi request reprint Discriminative analysis of early Alzheimer's disease based on two intrinsically anti-correlated networks with resting-state fMRI
    Kun Wang
    National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100080, China
    Med Image Comput Comput Assist Interv 9:340-7. 2006
    ..Our proposed model outperformed the other one significantly, and this implied that the two intrinsically anti-correlated networks may be a more susceptible part of the whole brain network in the early stage of AD...
  26. ncbi request reprint [Correlation of invasion, metastasis, and prognosis in low and middle rectal cancer]
    Wei jie He
    Department of General Surgery, Suzhou University Hospital, Suzhou 215006, P R China
    Ai Zheng 21:1222-5. 2002
    ..Based on these variables, a new classification system has been recommended. This study was designed to evaluate prognostic significance and risk factors of neoplasm in low and middle rectal cancer...
  27. ncbi request reprint Learning and matching of dynamic shape manifolds for human action recognition
    Liang Wang
    Monash University, Melbourne, Victoria, 3800, Australia
    IEEE Trans Image Process 16:1646-61. 2007
    ..g., partial occlusion, low-quality videos, changes in viewpoints, scales, and clothes; within-class variations caused by different subjects with different physical build; styles of motion; etc...
  28. ncbi request reprint BRDF invariant stereo using light transport constancy
    Liang Wang
    Department of Computer Science, University of Louisville, Louisville, KY 40507, USA
    IEEE Trans Pattern Anal Mach Intell 29:1616-26. 2007
    ..Importantly, the new constraint can be used to provide BRDF invariance to any existing stereo method whenever appropriate lighting variation is available...
  29. ncbi request reprint Altered functional connectivity in early Alzheimer's disease: a resting-state fMRI study
    Kun Wang
    National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, People s Republic of China
    Hum Brain Mapp 28:967-78. 2007
    ..In addition, the results also suggest that AD may disturb the correlation/anti-correlation effect in the two intrinsically anti-correlated networks...
  30. ncbi request reprint Improvement of the dissolution rate of nitrendipine using a new pulse combustion drying method
    Liang Wang
    Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, P R China
    Chem Pharm Bull (Tokyo) 55:1119-25. 2007
    ..Pulse combustion drying with low drying costs and high thermal efficiency is a promising method for the preparation of SD particles with improved properties without using organic solvent...
  31. ncbi request reprint Fine mapping of familial prostate cancer families narrows the interval for a susceptibility locus on chromosome 22q12.3 to 1.36 Mb
    Bo Johanneson
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Hum Genet 123:65-75. 2008
    ..Combining these results with data from the earlier ICPCG study reduces the three-recombination interval at 22q12.3 to approximately 1.36 Mb...
  32. ncbi request reprint Highly methylated genes in colorectal neoplasia: implications for screening
    Hongzhi Zou
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:2686-96. 2007
    ..Comethylation of these genes is common, and pursuit of complementary markers for methylation-negative neoplasms is a rational strategy to optimize screening sensitivity...
  33. pmc Analysis of the RNASEL gene in familial and sporadic prostate cancer
    Liang Wang
    Department of Laboratory Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Am J Hum Genet 71:116-23. 2002
    ..82; P=.03), as well as in the subset analyses. These results suggest that polymorphic changes within the RNASEL gene may be associated with increased risk of familial but not sporadic PC...
  34. pmc Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer
    Julius Gudmundsson
    deCODE Genetics, 101 Reykjavik, Iceland
    Nat Genet 40:281-3. 2008
    ..23 and 1.15; P = 3.9 x 10(-13) and 7.7 x 10(-9), respectively). The 2p15 variant shows a significantly stronger association with more aggressive, rather than less aggressive, forms of the disease...
  35. doi request reprint Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: a review of resting-state fMRI studies
    Yong Liu
    National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China
    Neuropsychologia 46:1648-56. 2008
    ..Finally, we summarize the main results and some prospects for future work...
  36. doi request reprint Default mode network as revealed with multiple methods for resting-state functional MRI analysis
    Xiang Yu Long
    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China
    J Neurosci Methods 171:349-55. 2008
    ..Moreover, the current results provided evidences that the brain areas within the two anti-correlated networks are highly integrated at both the intra- and inter-regional level...
  37. ncbi request reprint Induction of specific cytolytic T lymphocytes using fusions of hepatocellular carcinoma (HCC) patient-derived dendritic cells and allogeneic HCC cell line
    Xiao Yu Yin
    Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510080, China
    Hepatogastroenterology 55:155-9. 2008
    ..To assess the ability of hepatocellular carcinoma (HCC) patient-derived dendritic cells (DCs) fused with allogeneic HCC cell line to activate autologous lymphocytes to generate specific cytotoxic T lymphocytes (CTL) in vitro...
  38. doi request reprint Expression of CD40 and growth-inhibitory activity of CD40 ligand in colon cancer ex vivo
    Yugang Wu
    Department of Surgery, The First People Hospital of Changzhou and The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213000, China
    Cell Immunol 253:102-9. 2008
    ..In addition, rshCD40L induced apoptosis of the CD40(+) colon cancer cell lines. Theses results suggest that CD40 present in colon cancer, and rshCD40L may be of clinical use to inhibit human colon cancer growth...
  39. ncbi request reprint Regulation of interleukin-6-mediated PI3K activation and neuroendocrine differentiation by androgen signaling in prostate cancer LNCaP cells
    Shaozhen Xie
    George H Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester, Rochester, New York 14642, USA
    Prostate 60:61-7. 2004
    ..In this study, we investigate how androgen plays a role in IL-6-mediated NE differentiation in LNCaP cell line...
  40. pmc Mitochondrial genetic polymorphisms do not predict survival in patients with pancreatic cancer
    Thorvardur R Halfdanarson
    Department of Internal Medicine, Division of Hematology, Oncology and Blood and Marrow Transplantation, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    Cancer Epidemiol Biomarkers Prev 17:2512-3. 2008
    ..After adjusting for covariates and multiple comparisons, no association between any of the mitochondrial single nucleotide polymorphisms or haplogroups and survival was observed...
  41. ncbi request reprint Superresolution along extended depth of focus with binary-phase filters for the Gaussian beam
    Linbo Liu
    Graduate Programme in Bioengineering, National University of Singapore, Singapore
    J Opt Soc Am A Opt Image Sci Vis 25:2095-101. 2008
    ..Optimal filter designs are proposed for either high-resolution or ultra-large-DOF applications followed by experimental verifications...
  42. ncbi request reprint Evaluation of genetic variations in the androgen and estrogen metabolic pathways as risk factors for sporadic and familial prostate cancer
    Julie M Cunningham
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:969-78. 2007
    ..Given that the point estimates for the odds ratio for each of these polymorphisms are <2.0, much larger sample sizes will be required for confirmation...
  43. ncbi request reprint [Expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor in prostate cancer and its significance]
    Liang Wang
    Department of Urology, Chengdu Command General Hospital, Chengdu, Sichuan 610083, China
    Zhonghua Nan Ke Xue 12:57-9. 2006
    ..Objective: To study the expression of hypoxia-inducible factor 1 alpha (HIF-1 alpha) and vascular endothelial growth factor (VEGF) in prostate cancer (PCa) and its biological significance...
  44. ncbi request reprint [Expressions of Axin and beta-catenin in non-small cell lung cancer]
    Hong Tao Xu
    Department of Pathology, College of Basic Medical Science, China Medical University, Shenyang 110001, China
    Zhonghua Bing Li Xue Za Zhi 34:519-23. 2005
    ..To investigate the protein expression of Axin and beta-catenin, the exon 3 mutation status of beta-catenin and their clinicopathological correlations in non-small cell lung cancer (NSCLC)...
  45. ncbi request reprint Perfusion MR imaging and proton MR spectroscopy in a case of dysembryoplastic neuroepithelial tumor
    Liang Wang
    Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China
    Chin Med J (Engl) 118:1134-6. 2005
  46. ncbi request reprint [Expression of p120ctn and its significance in non-small cell lung cancer]
    Cheng Yao Xie
    Department of Pathology, College of Basic Medical Science, China Medical University, Shenyang 110001, China
    Zhonghua Bing Li Xue Za Zhi 34:206-10. 2005
    ..To investigate the expression of p120(ctn) in non-small cell lung cancer (NSCLC) and its correlation with the clinical and pathologic parameters...
  47. ncbi request reprint Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells
    Lin Yang
    George Whipple Laboratory for Cancer Research, Department of Pathology, The Cancer Center, University of Rochester, Rochester, New York 14642, USA
    J Biol Chem 280:33558-65. 2005
    ..Together, our data provide the first model to explain how PI3K/Akt and AR can cooperate to control LNCaP cell growth and death under normal conditions...
  48. ncbi request reprint The impact of price regulation on the launch delay of new drugs--evidence from twenty-five major markets in the 1990s
    Patricia M Danzon
    Health Care Systems Department, The Wharton School, University of Pennsylvania, Philadelphia, 19104 6218, USA
    Health Econ 14:269-92. 2005
    ..Controlling for expected price and volume, country effects for the likely parallel export countries are significantly negative...
  49. ncbi request reprint Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells
    Liang Wang
    George Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester Medical Center, New York 14642, USA
    J Biol Chem 279:32444-52. 2004
    ..Together, our data demonstrated that GSK3 beta may function as a repressor to suppress AR-mediated transactivation and cell growth, which may provide a new strategy to modulate the AR-mediated prostate cancer growth...
  50. pmc Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells
    Liang Wang
    George H Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester Medical Center, Rochester, New York 14642, USA
    Mol Cell Biol 24:2202-13. 2004
    ..Together, our data provide the first linkage between androgen-AR signals and radiation-induced responses. Further studies of the influence of hRad9 on prostate cancer growth may provide potential new therapeutic approaches...
  51. ncbi request reprint No association of germline alteration of MSR1 with prostate cancer risk
    Liang Wang
    Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, 920 Hilton Building, Mayo Clinic and Foundation, Rochester, Minnesota, USA
    Nat Genet 35:128-9. 2003
    ..Our results do not support MSR1 as a risk factor for prostate cancer...
  52. ncbi request reprint Abnormal beta-catenin and reduced axin expression are associated with poor differentiation and progression in non-small cell lung cancer
    Hong Tao Xu
    Department of Pathology, College of Basic Medical Sciences, China Medical University, Shenyang, China
    Am J Clin Pathol 125:534-41. 2006
    ..Reduced axin expression, but not mutation in exon 3, might be an important explanation for the abnormal beta-catenin expression in NSCLC...
  53. ncbi request reprint Higher frequency of diploidy in young-onset microsatellite-stable colorectal cancer
    Lisa A Boardman
    Department of Gastroenterology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Cancer Res 13:2323-8. 2007
    ..The clinicopathologic features of MSS CIN- CRC are not well delineated. We assessed the relationship between age and chromosomal instability (CIN) status as measured by ploidy and allelic imbalance in a series of MSS tumors...
  54. ncbi request reprint Two common chromosome 8q24 variants are associated with increased risk for prostate cancer
    Liang Wang
    Departments of Laboratory Medicine and Pathology, Health Sciences Research, and Urology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Cancer Res 67:2944-50. 2007
    ..00005). These results further confirm the importance of these two polymorphic variants (rs1447295 and DG8S737) as risk factors for PC. However, the mechanism explaining this increased risk has not yet been established...
  55. ncbi request reprint Androgen receptor (AR) NH2- and COOH-terminal interactions result in the differential influences on the AR-mediated transactivation and cell growth
    Cheng Lung Hsu
    The George H Whipple Laboratory for Cancer Research, Department of Pathology, and the Cancer Center, University of Rochester Medical Center, Rochester, New York 14642, USA
    Mol Endocrinol 19:350-61. 2005
    ..Therefore, drugs designed by targeting AR N-C interaction as a therapeutic intervention for prostate cancer treatment may face unpredictable in vivo effects...
  56. ncbi request reprint Regional coherence changes in the early stages of Alzheimer's disease: a combined structural and resting-state functional MRI study
    Yong He
    National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100080, PR China
    Neuroimage 35:488-500. 2007
    ..Finally, our study indicated that regional brain atrophy could be an important consideration in functional imaging studies of neurodegenerative diseases...
  57. pmc Mutations in CHEK2 associated with prostate cancer risk
    Xiangyang Dong
    Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic Mayo Medical School, Rochester, MN 55905, USA
    Am J Hum Genet 72:270-80. 2003
    ..Overall, our data suggest that mutations in CHEK2 may contribute to prostate cancer risk and that the DNA-damage-signaling pathway may play an important role in the development of prostate cancer...
  58. ncbi request reprint Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells
    Lin Yang
    George Whipple Lab for Cancer Research, Department of Pathology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Biochem Biophys Res Commun 305:462-9. 2003
    ..Together, our results indicate that the balance of these various pathways may then determine the overall effect of IL-6 on AR transactivation...
  59. ncbi request reprint Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk
    Xianshu Wang
    Department of Laboratory Medicine, Mayo Clinic Mayo Clinical Medical College, Rochester, Minnesota 55905, USA
    Cancer Res 66:10302-7. 2006
    ....
  60. ncbi request reprint Dendritic cell as therapeutic vaccines against tumors and its role in therapy for hepatocellular carcinoma
    Kang Sun
    Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, China
    Cell Mol Immunol 3:197-203. 2006
    ..DC-based tumor vaccines have become a novel immunoadjuvant therapy for HCC...
  61. ncbi request reprint Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer
    Yueh Chiang Hu
    George Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester, Rochester, New York 14642, USA
    J Biol Chem 279:33438-46. 2004
    ....