L Wang

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi request reprint A patient-specific Monte Carlo dose-calculation method for photon beams
    L Wang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Med Phys 25:867-78. 1998
  2. ncbi request reprint The epidemiology of Her-2/neu and P53 in breast cancer
    J L Bernstein
    Mount Sinai School of Medicine, Department of Community Medicine, New York, Nueva York 10029, USA
    Salud Publica Mex 41:S114-23. 1999
  3. pmc An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors
    D Chitale
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Oncogene 28:2773-83. 2009
  4. ncbi request reprint Measuring tumor response and shape change on CT: esophageal cancer as a paradigm
    L H Schwartz
    Department of Radiology, Biostatistics and Epidemiology and Medicine, Memorial Sloan Kettering Cancer Center, New York, 10021, USA
    Ann Oncol 17:1018-23. 2006
  5. ncbi request reprint Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
    Y Jing
    Department of Medicine, Division of Medical Oncology, Mount Sinai School of Medicine, New York, NY 10029 6547, USA
    Blood 97:264-9. 2001
  6. doi request reprint Post-processing of dynamic gadolinium-enhanced magnetic resonance imaging exams of the liver: explanation and potential clinical applications for color-coded qualitative and quantitative analysis
    L Wang
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Acta Radiol 49:6-18. 2008
  7. ncbi request reprint Dosimetric evaluation of MRI-based treatment planning for prostate cancer
    L Chen
    Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Phys Med Biol 49:5157-70. 2004
  8. ncbi request reprint Study of hepatic function matching between Banna minipig inbred and humans
    L Zhang
    Lab of Transplant Engineering and Immunology, West China Hospital, Sichuan University, People s Republic of China
    Transplant Proc 36:2492-4. 2004
  9. ncbi request reprint Randomized clinical trial of the effects of abdominal drainage after elective hepatectomy using the crushing clamp method
    H C Sun
    Liver Cancer Institute and Zhong Shan Hospital, Fudan University, Shanghai 200032, China
    Br J Surg 93:422-6. 2006
  10. ncbi request reprint Discordant genetic changes in ovarian and endometrial endometrioid carcinomas: a potential pitfall in molecular diagnosis
    K H Chang
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4095, USA
    Int J Gynecol Cancer 16:178-82. 2006

Detail Information

Publications66

  1. ncbi request reprint A patient-specific Monte Carlo dose-calculation method for photon beams
    L Wang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Med Phys 25:867-78. 1998
    ..375 cm, was less than 14 h on a 175-MHz computer with a standard deviation of 1.5% in the high-dose region...
  2. ncbi request reprint The epidemiology of Her-2/neu and P53 in breast cancer
    J L Bernstein
    Mount Sinai School of Medicine, Department of Community Medicine, New York, Nueva York 10029, USA
    Salud Publica Mex 41:S114-23. 1999
    ..We conclude that more research is needed to understand the complex relationships between genetic alterations and etiologic risk factors for breast cancer...
  3. pmc An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors
    D Chitale
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Oncogene 28:2773-83. 2009
    ....
  4. ncbi request reprint Measuring tumor response and shape change on CT: esophageal cancer as a paradigm
    L H Schwartz
    Department of Radiology, Biostatistics and Epidemiology and Medicine, Memorial Sloan Kettering Cancer Center, New York, 10021, USA
    Ann Oncol 17:1018-23. 2006
    ..We evaluated the impact of Response Evaluation Criteria in Solid Tumors (RECIST), World Health Organization (WHO) criteria and tumor shape on response assessment in patients with metastatic esophageal cancer...
  5. ncbi request reprint Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
    Y Jing
    Department of Medicine, Division of Medical Oncology, Mount Sinai School of Medicine, New York, NY 10029 6547, USA
    Blood 97:264-9. 2001
    ..Although in vitro data do not always translate to in vivo response, toxicity and potential drug antagonism may be diminished by decreasing the concentration of As(2)O(3) when given at the same time with therapeutic levels of tRA...
  6. doi request reprint Post-processing of dynamic gadolinium-enhanced magnetic resonance imaging exams of the liver: explanation and potential clinical applications for color-coded qualitative and quantitative analysis
    L Wang
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Acta Radiol 49:6-18. 2008
    ..In addition, these tools may facilitate the diagnostic workup of disease for detection, characterization, staging, and monitoring of antitumor therapy, and hold incremental value to the widely used tumor response criteria...
  7. ncbi request reprint Dosimetric evaluation of MRI-based treatment planning for prostate cancer
    L Chen
    Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Phys Med Biol 49:5157-70. 2004
    ..The difference in the target dose between CT- and MRI-based plans using homogeneous geometry was within 2.5%. Our results suggest that MRI-based treatment planning is suitable for radiotherapy of prostate cancer...
  8. ncbi request reprint Study of hepatic function matching between Banna minipig inbred and humans
    L Zhang
    Lab of Transplant Engineering and Immunology, West China Hospital, Sichuan University, People s Republic of China
    Transplant Proc 36:2492-4. 2004
    ..BMI livers may have stronger functions compared with those of humans. No incompatibility was identified in hepatic function between BMI and humans...
  9. ncbi request reprint Randomized clinical trial of the effects of abdominal drainage after elective hepatectomy using the crushing clamp method
    H C Sun
    Liver Cancer Institute and Zhong Shan Hospital, Fudan University, Shanghai 200032, China
    Br J Surg 93:422-6. 2006
    ..Abdominal drainage is a standard procedure after hepatectomy, but this practice has been challenged recently...
  10. ncbi request reprint Discordant genetic changes in ovarian and endometrial endometrioid carcinomas: a potential pitfall in molecular diagnosis
    K H Chang
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4095, USA
    Int J Gynecol Cancer 16:178-82. 2006
    ..Because of these discordant genetic changes, great caution should be taken when distinguishing between primary and metastatic tumors on the basis of microsatellite markers...
  11. ncbi request reprint Endovascular graft exclusion for abdominal aortic aneurysms: 3D contrast-enhanced MR angiography
    Q Liu
    Department of Radiology, Changhai Hospital, Second Military Medical University, 174 Changhai Rd, Shanghai 200433, China
    Abdom Imaging 31:347-60. 2006
  12. ncbi request reprint HTPAP gene on chromosome 8p is a candidate metastasis suppressor for human hepatocellular carcinoma
    X Wu
    Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Oncogene 25:1832-40. 2006
    ..These suggested that HTPAP is a novel metastatic suppressor gene for HCC. The mechanism of the effect of HTPAP on HCC metastasis is not clear yet and deserves further investigation...
  13. ncbi request reprint Geographic distribution, virologic and clinical characteristics of hepatitis B virus genotypes in China
    G Zeng
    Hepatology Unit and Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
    J Viral Hepat 12:609-17. 2005
    ..HBV DNA recombination over the surface and precore/core genes increases the diversity of HBV strains and may have diagnostic and clinical implications...
  14. ncbi request reprint A method for repositioning of stereotactic brain patients with the aid of real-time CT image guidance
    K Paskalev
    Department of Radiation Oncology Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Phys Med Biol 50:N201-7. 2005
    ..05 mm, and they were not statistically significant. The random errors (one standard deviation) were from 0.35 mm (lateral) to 0.58 mm (vertical). The average value of the combined 3D difference was 0.75 mm...
  15. ncbi request reprint Preclinical detection of Alzheimer's disease: hippocampal shape and volume predict dementia onset in the elderly
    J G Csernansky
    Department of Psychiatry, Alzheimer s Disease Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 25:783-92. 2005
    ..These results suggest that inward deformation of the left hippocampal surface in a zone corresponding to the CA1 subfield is an early predictor of the onset of DAT in nondemented elderly subjects...
  16. ncbi request reprint CFD simulation of aggregation and breakage processes in laminar Taylor-Couette flow
    L Wang
    Department of Chemical Engineering, Iowa State University, 2114 Sweeney Hall, Ames, IA 50011 2230, USA
    J Colloid Interface Sci 282:380-96. 2005
    ....
  17. ncbi request reprint VEGF-induced phosphorylation of Bcl-2 influences B lineage leukemic cell response to apoptotic stimuli
    L Wang
    Department of Pediatrics, Robert C Byrd Health Sciences Center, School of Medicine, West Virginia University, Morgantown, WV 26506, USA
    Leukemia 19:344-53. 2005
    ..These observations suggest that optimal protection of leukemic cells by VEGF may require activation of a pathway that includes Bcl-2 phosphorylation...
  18. ncbi request reprint Morphological alteration and biological properties of hepatocytes not related to tumorigenesis following transfection with HCV core protein
    J Gu
    Department of Viral Immunology, Institute of Medical Biology, Chinese Academy of Medical Sciences, Kunming, China
    J Viral Hepat 12:20-6. 2005
    ..In conclusion, the hepatocytes transfected with the HCV core gene revealed that the core protein expressed induced pathological changes of degeneration, probably related indirectly to tumorigenicity...
  19. ncbi request reprint Stereotactic IMRT for prostate cancer: dosimetric impact of multileaf collimator leaf width in the treatment of prostate cancer with IMRT
    L Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 5:29-41. 2004
    ..78). In conclusion, the use of the mMLC for IMRT of the prostate resulted in significant improvement in the DVH parameters of the prostate and critical organs, which may improve the therapeutic ratio...
  20. pmc Economic burden of smoking in China, 2000
    H Y Sung
    Institute for Health and Aging, School of Nursing, University of California, San Francisco, California 94118, USA
    Tob Control 15:i5-11. 2006
    ..To assess the health-related economic burden attributable to smoking in China for persons aged 35 and older...
  21. ncbi request reprint Gene expression profile of transgenic mouse kidney reveals pathogenesis of hepatitis B virus associated nephropathy
    J Ren
    Key Laboratory of Medical Molecular Virology, Institute of Medical Microbiology, Shanghai Medical College, Fudan University, Shanghai, China
    J Med Virol 78:551-60. 2006
    ..Results indicate that expression of HBsAg and HBcAg in tubular epithelial cells of the kidney per se can up-regulate complement-mediated inflammatory gene pathways, in addition to immune complex formation...
  22. ncbi request reprint Expression of DPC4/Smad4 in non-small-cell lung carcinoma and its relationship with angiogenesis
    Z Ke
    Department of Pathology, Medical School of Sun Yat sen University, Guangzhou, Province, Guandong, China
    Neoplasma 55:323-9. 2008
    ..Our findings indicated that DPC4 might be an important biomarker for malignant transformation and be involved in preventing the tumor metastasis by inhibiting tumor angiogenesis...
  23. doi request reprint Myoepithelioma of the parotid gland: CT imaging findings
    S Wang
    Department of Radiology, Ninth People s Hospital, Medical School, Shanghai Jiao Tong University, Shanghai, People s Republic of China
    AJNR Am J Neuroradiol 29:1372-5. 2008
    ..Only a few case reports describing CT imaging features of ME have been published. The aim of this study was to describe and characterize the CT findings of MEs of the parotid gland...
  24. doi request reprint A compact linac for intensity modulated proton therapy based on a dielectric wall accelerator
    G J Caporaso
    Lawrence Livermore National Laboratory, Livermore, CA 94550, USA
    Phys Med 24:98-101. 2008
    ..The status of the developmental new technologies that make the compact system possible will be reviewed. These include, high gradient vacuum insulators, solid dielectric materials, SiC photoconductive switches and compact proton sources...
  25. ncbi request reprint Rituximab in combination with CHOP chemotherapy for the treatment of diffuse large B cell lymphoma in Chinese patients
    J M Li
    Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Second Medical University SSMU, Shanghai, China
    Ann Hematol 86:639-45. 2007
    ..Five patients with a history of chronic hepatitis B experienced a reactivation of viral hepatitis. The rituximab-CHOP combination was effective and well tolerated in Chinese patients with newly diagnosed DLBCL...
  26. ncbi request reprint Epitope mapping of series of monoclonal antibodies against the hepatocellular carcinoma-associated antigen HAb18G/CD147
    X M Ku
    Cell Engineering Research Center and Department of Cell Biology, State Key Laboratory of Cancer Biology, The Fourth Military Medical University, Xi an, China
    Scand J Immunol 65:435-43. 2007
    ..These key residues can be used as potential drug target in cancer therapy...
  27. ncbi request reprint Shape mapping of the hippocampus in young children with autism spectrum disorder
    S R Dager
    Department of Radiology, University of Washington, Seattle, WA 98105, USA
    AJNR Am J Neuroradiol 28:672-7. 2007
    ..We hypothesized the occurrence of characteristic hippocampal-shape alterations in young children with autistic spectrum disorder (ASD) who also exhibit deficits on neuropsychologic tests of medial temporal lobe (MTL) function...
  28. ncbi request reprint The pharmacogenetics research network: from SNP discovery to clinical drug response
    K M Giacomini
    Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, USA
    Clin Pharmacol Ther 81:328-45. 2007
    ..Seven major topics are included: informatics (PharmGKB), cardiovascular, pulmonary, addiction, cancer, transport, and metabolism...
  29. ncbi request reprint Population balance modeling of aggregation and breakage in turbulent Taylor-Couette flow
    M Soos
    Institute for Chemical and Bioengineering, Department of Chemistry and Applied Bioscience, ETH Zurich, 8093 Zurich, Switzerland
    J Colloid Interface Sci 307:433-46. 2007
    ..In order to correctly capture the right-hand side of the CSD (large aggregates) at the higher solid volume fraction, a modified aggregation rate prefactor was used in the population balance model...
  30. ncbi request reprint Silencing L-selectin expression by siRNA attenuated metastasis of murine lymphoid neoplasm cell P388D1 to peripheral lymph nodes
    Y Zuo
    Leukemia 21:180-3. 2007
  31. ncbi request reprint Rifampicin plus pyrazinamide versus isoniazid for treating latent tuberculosis infection: a meta-analysis
    X F Gao
    Chinese Evidence Based Medicine Centre, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
    Int J Tuberc Lung Dis 10:1080-90. 2006
    ..Six trials from Haiti, Mexico, the U.S.A., Brazil, Spain, Zambia and Hong Kong...
  32. ncbi request reprint Efficacy and safety of adeno-associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy
    T Vandendriessche
    Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, University of Leuven, Leuven, Belgium
    J Thromb Haemost 5:16-24. 2007
    ..Adeno-associated viral (AAV) and lentiviral vectors are promising vectors for gene therapy for hemophilia because they are devoid of viral genes and have the potential for long-term gene expression...
  33. ncbi request reprint Homoharringtonine in combination with cytarabine and aclarubicin resulted in high complete remission rate after the first induction therapy in patients with de novo acute myeloid leukemia
    J Jin
    Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang, PR China
    Leukemia 20:1361-7. 2006
    ..The toxicities associated with HAA regimen were acceptable, and the most common toxicity was infection. This study suggested that HAA regimen might be a well-tolerable, effective induction regimen in young adult patients with AML...
  34. ncbi request reprint Daily target localization for prostate patients based on 3D image correlation
    K Paskalev
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Phys Med Biol 49:931-9. 2004
    ..The impact of image noise on the performance of the algorithm has been tested. The results show that the algorithm accurately adjusts for target positional changes even with Gaussian noise levels as high as 20% inserted...
  35. pmc Treatment of colorectal and hepatocellular carcinomas by adenoviral mediated gene transfer of endostatin and angiostatin-like molecule in mice
    V Schmitz
    Division of Hepatology and Gene Therapy, Department of Medicine, Medical School, University of Navarra, Pamplona, Spain
    Gut 53:561-7. 2004
    ....
  36. ncbi request reprint Evidence for expression of a single distinct form of mammalian cysteine dioxygenase
    M H Stipanuk
    Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853 6301, USA
    Amino Acids 26:99-106. 2004
    ..e., 23.5 kDa based on mass spectrometry) monomer and that this active form is probably derived by post-translational modification of the 23 kDa gene product...
  37. ncbi request reprint Vgamma2Vdelta2 T-cell receptor-mediated recognition of aminobisphosphonates
    H Das
    Lymphocyte Biology Section, Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA
    Blood 98:1616-8. 2001
    ....
  38. ncbi request reprint Focal adhesion kinase affects the sensitivity of human hepatocellular carcinoma cell line SMMC-7721 to tumor necrosis factor-alpha/cycloheximide-induced apoptosis by regulating protein kinase B levels
    Y Fang
    Key Laboratory of Glycoconjugate Research, Ministry of Health, Department of Biochemistry, Shanghai Medical University, China
    Eur J Biochem 268:4513-9. 2001
    ..These results suggest that FAK can affect the sensitivity of SMMC-7721 cells to TNF-alpha/Chx-induced apoptosis in a biphasic manner by regulating PKB levels...
  39. ncbi request reprint hMLH1 and hMSH2 expression in human hepatocellular carcinoma
    L Wang
    Department of Laboratory Medicine and Pathology, Mayo Medical School, Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Int J Oncol 19:567-70. 2001
    ..None of the tumors showed MSI at the BAT26 locus. These findings suggest that defective MMR does not contribute significantly to hepatocellular carcinogenesis...
  40. ncbi request reprint Mouse histamine N-methyltransferase: cDNA cloning, expression, gene cloning and chromosomal localization
    L Wang
    Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Graduate School Mayo Clinic Mayo Foundation, Rochester, MN 55905 USA
    Inflamm Res 50:300-8. 2001
    ..We set out to clone a mouse liver HNMT cDNA and the mouse HNMT gene as steps toward characterizing molecular genetic mechanisms involved in the regulation of this important histamine-metabolizing enzyme...
  41. ncbi request reprint Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC type II mutations
    S Y Cai
    Liver Center, Yale University School of Medicine, New Haven, Connecticut 06520-8019, USA
    Am J Physiol Gastrointest Liver Physiol 281:G316-22. 2001
    ..These studies demonstrate that Bsep is a liver-specific ATP-dependent export pump that is highly conserved throughout evolution and provide insights into critical determinants for the function of this transporter in higher vertebrates...
  42. ncbi request reprint [[(18)F]N-(4'-fluorobenzyl)-4-(3-bromophenyl) acetamide for imaging the sigma receptor status of tumors: comparison with [(18)F]FDG, and [(125)I]IUDR
    R H Mach
    Department of Radiology-PET Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
    Nucl Med Biol 28:451-8. 2001
    ..However, additional studies will be needed to compare sigma(2)-selective imaging agents with [(18)F]FLT in order to determine which is the more appropriate imaging agent for measuring the proliferative status of breast tumors with PET...
  43. ncbi request reprint Allelic loss and gain, but not genomic instability, as the major somatic mutation in primary hepatocellular carcinoma
    G Wang
    National Laboratory for Oncogene and Related Genes, Shanghai Cancer Institute, Shanghai, China
    Genes Chromosomes Cancer 31:221-7. 2001
    ..Interestingly, microsatellite instability was rarely seen in our patients, in contrast to that observed in European HCC samples...
  44. ncbi request reprint Hypermethylation at 9q32-33 tumour suppressor region is age-related in normal urothelium and an early and frequent alteration in bladder cancer
    T Habuchi
    Department of Urology, Akita University School of Medicine, Akita, Japan
    Oncogene 20:531-7. 2001
    ..Methylator or methylation-resistant phenotype seems to be maintained during multifocal development or recurrence of most TCCs...
  45. ncbi request reprint Il-12 antagonism enhances apoptotic death of T cells within hepatic allografts from Flt3 ligand-treated donors and promotes graft acceptance
    W Li
    Thomas E. Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Immunol 166:5619-28. 2001
    ....
  46. ncbi request reprint Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation
    K Rose
    Centre for Genome Research and Centre for Neuroscience, University of Edinburgh, King s Buildings, Edinburgh EH9 3JQ, United Kingdom
    J Biol Chem 276:23937-44. 2001
    ..CYP7B is thus a major extrahepatic steroid and oxysterol hydroxylase and provides the predominant route for local metabolism of DHEA and related molecules in brain and other tissues...
  47. ncbi request reprint Bone anabolic effects of separate and combined therapy with growth hormone and parathyroid hormone on femoral neck in aged ovariectomized osteopenic rats
    L Wang
    Department of Physiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Mech Ageing Dev 122:89-104. 2001
    ..Combined therapy with GH+PTH was more effective in rebuilding cortical bone and cancellous bone than either therapy alone in the aged ovariectomized osteopenic rats, which is in line with our hypothesis...
  48. ncbi request reprint Increased insulin receptor substrate-1 and enhanced skeletal muscle insulin sensitivity in mice lacking CCAAT/enhancer-binding protein beta
    L Wang
    Department of Nutrition, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4935, USA
    J Biol Chem 275:14173-81. 2000
    ..These results demonstrate that C/EBPbeta deletion decreases plasma FFA levels and increases insulin signal transduction specifically in skeletal muscle, and both contribute to increased whole-body insulin sensitivity...
  49. ncbi request reprint Neurotensin receptor-1 mRNA analysis in normal pancreas and pancreatic disease
    L Wang
    Department of Visceral and Transplantation Surgery, University of Bern, Inselspital, Switzerland
    Clin Cancer Res 6:566-71. 2000
    ..However, its relatively high levels in CP excludes NTR-1 mRNA as a specific parameter for pancreatic cancer and for the differentiation of pancreatic cancer from CP...
  50. ncbi request reprint Telomerase activity and homozygous deletions of the p16 gene in liver metastases of colorectal carcinoma
    J Ma
    Department of Gastrointestinal and Pancreatic Surgery, First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China
    Chin Med J (Engl) 114:1068-72. 2001
    ..However, telomerase activation and homozygous deletions of the p16 gene might not be the initiating event in liver metastases of colorectal carcinoma...
  51. ncbi request reprint Separate and combined effects of growth hormone and parathyroid hormone on cortical bone osteopenia in ovariectomized aged rats
    M J Banu
    Department of Physiology, The University of Texas Health Science Center at San Antonio, 78229-3900, USA
    Aging (Milano) 13:282-92. 2001
    ..Growth hormone increased periosteal bone formation, while PTH stimulated endocortical bone formation and in combination GH+PTH produced complementary effects thereby reversing osteopenia...
  52. pmc Antibacterial effect of human V gamma 2V delta 2 T cells in vivo
    L Wang
    Lymphocyte Biology Section, Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Invest 108:1349-57. 2001
    ....
  53. ncbi request reprint [The diagnosis and treatment of isolated sphenoid sinus disease]
    N Zhang
    Department of Otolaryngology, West China Hospital of Sichuan University, Chengdu 610041
    Lin Chuang Er Bi Yan Hou Ke Za Zhi 15:489-90. 2001
    ..CONCLUSION: Nasal endoscopy and CT/MRI scan could provide a precise diagnosis for isolated sphenoid sinus disease and endoscopic surgery is valuable in its treatment...
  54. ncbi request reprint [A clinicopathological study of clear cell sarcoma of the kidney]
    L He
    Department of Pathology, Beijing Children's Hospital, Beijing 100045, China
    Zhonghua Bing Li Xue Za Zhi 30:422-5. 2001
    ..CONCLUSION: CCSK is a common renal neoplasm of childhood. CCSK may arise from renal mesenchymal cells and has the propensity to metastasize to the bone with poor clinical outcome...
  55. ncbi request reprint [Cox multivariate analysis of prognosis and proposal on a modified staging system of thymoma]
    J Li
    Department of Thoracic Surgical Oncology, Cancer Institute (Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
    Zhonghua Zhong Liu Za Zhi 23:500-2. 2001
    ..III b-extensive invasion into the nearby organs, and resection is impossible. Stage IV a-pleural or pericardial dissemination, IV b-lymphatic or hematogenous metastasis...
  56. ncbi request reprint [Diagnosis and surgical treatment of double primary lung cancer]
    Y Wang
    Department of Thoracic Surgery, Cancer Institute (Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
    Zhonghua Zhong Liu Za Zhi 23:428-30. 2001
    ..Conservative operation and incomplete lymph node dissection, being the chief reasons of poor outcome, should be stressed...
  57. ncbi request reprint [Second primary lung cancer in laryngeal cancer patients: report on 36 cases]
    Y Gao
    Cancer Institute (Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
    Zhonghua Zhong Liu Za Zhi 23:341-3. 2001
    ..The development of the second primary lung cancer is not related to the treatment of the initial laryngeal malignancies. Surgery plus external radiotherapy provides better results than surgery or radiotherapy alone...
  58. ncbi request reprint [Treatment of stage II non-Hodgkin's lymphoma: analysis of 268 patients]
    W Wang
    Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
    Zhonghua Zhong Liu Za Zhi 23:335-7. 2001
    ..CONCLUSION: For patients with stage II intermediate and high grade NHL, combination therapy of C + R + C is recommended. Radiation alone can only be used for patients with stage II low grade NHL...
  59. ncbi request reprint [Carcinoid of trachea and bronchus: a report of 20 cases]
    Y Wang
    Department of Thoracic Surgery, Cancer Institute (Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
    Zhonghua Zhong Liu Za Zhi 23:70-2. 2001
    ..CONCLUSION: Surgical resection of carcinoid is indicated not only for early cases, but also for patients in stage III a and III b. The age and pulmonary function of the patients are the chief factors determining the surgical approach...
  60. ncbi request reprint [A study on cyclooxygenase-2 protein expression in esophageal carcinoma and premalignant lesions]
    L Wang
    Department of Pathology, First Hospital of Harbin Medical University, Harbin 150001, China
    Zhonghua Zhong Liu Za Zhi 23:14-6. 2001
    ..CONCLUSION: The Cox-2 protein expression may be associated with the development of the esophageal adenocarcinomas but not esophageal squamous-cell carcinomas...
  61. ncbi request reprint [Influence of focal adhesion kinase (FAK) on the biological behaviors of human hepatocellular carcinoma cells]
    Y Fang
    Department of Biochemistry, Ministry of Public Health Key Laboratory of Glycoconjugate Research, Shanghai Medical University, Shanghai 200032, China
    Zhonghua Zhong Liu Za Zhi 23:125-7. 2001
    ..CONCLUSION: FAK is overexpressed in the human hepatocellular carcinoma cell line SMMC-7721. Reducing the FAK expression can partly reverse the malignant behaviors of the cell line...
  62. ncbi request reprint Autologous peripheral blood stem cell transplantation in the patients with hematologic malignancies and solid tumors
    X Ke
    Hematology Department, Third Hospital, Peking University School of Medicine, Beijing 100083, China
    Chin Med J (Engl) 114:196-9. 2001
    ....
  63. ncbi request reprint Endotoxin impairs biliary transport of sparfloxacin and its glucuronide in rats
    M Nadai
    Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tenpaku-ku, 468-8503, Nagoya, Japan
    Eur J Pharmacol 432:99-105. 2001
    ..These findings suggest that endotoxin decreases the biliary excretion of sparfloxacin and its glucuronide probably due to impairment of their hepatobiliary transport systems and renal handling...
  64. ncbi request reprint Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat
    J Lee
    Liver Center and Department of Medicine, Yale University School of Medicine, 1080 LMP, New Haven, CT 06520-8019, USA
    Gastroenterology 121:1473-84. 2001
    ..These responses may facilitate extrahepatic pathways for bile salt excretion during cholestasis...
  65. pmc Effect of endotoxin on P-glycoprotein-mediated biliary and renal excretion of rhodamine-123 in rats
    H Ando
    Department of Second Surgery, Nagoya University School of Medicine, Nagoya, Japan
    Antimicrob Agents Chemother 45:3462-7. 2001
    ..pneumoniae endotoxin dramatically decreases P-glycoprotein-mediated biliary and renal excretion of rhodamine-123 probably by decreasing the expression of Mdr1a, which is likely due to increased plasma TNF-alpha levels...
  66. pmc The role of the LDL receptor in apolipoprotein B secretion
    J Twisk
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Clin Invest 105:521-32. 2000
    ..These studies show that the LDL receptor alters the proportion of apoB that escapes co- or post-translational presecretory degradation and mediates the reuptake of newly secreted apoB-containing lipoprotein particles...