Research Topics
| Robert A VeselisSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
Memory: a guide for anaesthetistsRobert A Veselis
Department of Anesthesiology and Critical Core Medicine, Memorial Sloan Kettering Cancer Center, New York 10021, USA
Best Pract Res Clin Anaesthesiol 21:297-312. 2007..A synthesis of diverse knowledge is undertaken to identify potential mechanisms of amnesic drug effect, which will, of course, require further research to delineate...
Propofol and thiopental do not interfere with regional cerebral blood flow response at sedative concentrationsRobert A Veselis
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Anesthesiology 102:26-34. 2005..Anesthetics may affect the regional cerebral blood flow (rCBF) response associated with increased brain activity in humans. rCBF was measured as auditory stimulus rate was increased during propofol and thiopental administration...
Low-dose propofol-induced amnesia is not due to a failure of encoding: left inferior prefrontal cortex is still activeRobert A Veselis
Department of Anesthesiology Box 24, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
Anesthesiology 109:213-24. 2008..Propofol may produce amnesia by affecting encoding. The hypothesis that propofol weakens encoding was tested by measuring regional cerebral blood flow during verbal encoding...
Thiopental and propofol affect different regions of the brain at similar pharmacologic effectsRobert A Veselis
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Box 24, New York, NY 10021, USA
Anesth Analg 99:399-408, table of contents. 2004..At similar levels of drug effect, propofol and thiopental affect different regions of the brain. These differences may help to identify the loci of action for the nonsedative effects of propofol, such as amnesia...
Propofol and midazolam inhibit conscious memory processes very soon after encoding: an event-related potential study of familiarity and recollection in volunteersRobert A Veselis
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, New York, New York 10065, USA
Anesthesiology 110:295-312. 2009..Intravenous drugs active via gamma-aminobutyric acid receptors to produce memory impairment during conscious sedation. Memory function was assessed using event-related potentials (ERPs) while drug was present...
A neuroanatomical construct for the amnesic effects of propofolRobert A Veselis
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Anesthesiology 97:329-37. 2002..Drug-related changes in regional cerebral blood flow (rCBF) were located in comparison with rCBF increases during a simple word memory task...
Drug-induced amnesia is a separate phenomenon from sedation: electrophysiologic evidenceR A Veselis
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Anesthesiology 95:896-907. 2001..These drugs also produce profound changes in the auditory event-related potential (ERP). The ability of various ERP components to predict changes in sedation and memory produced by various drugs was tested...
Midazolam changes cerebral blood flow in discrete brain regions: an H2(15)O positron emission tomography studyR A Veselis
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center and Cornell University Medical College, New York, New York 10021, USA
Anesthesiology 87:1106-17. 1997..Changes in regional cerebral blood flow (rCBF) determined with H2(15)O positron emission tomographic imaging can identify neural circuits affected by centrally acting drugs...
The comparative amnestic effects of midazolam, propofol, thiopental, and fentanyl at equisedative concentrationsR A Veselis
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Anesthesiology 87:749-64. 1997..The authors evaluated the effects of midazolam, propofol, thiopental, and fentanyl on volunteer participants' memory for words and pictures at equisedative concentrations...
Visual P2-N2 complex and arousal at the time of encoding predict the time domain characteristics of amnesia for multiple intravenous anesthetic drugs in humansKane O Pryor
Department of Anesthesiology, Weill Cornell Medical College, New York, New York, USA
Anesthesiology 113:313-26. 2010..Fundamental questions remain in characterizing anesthetic amnesia and identifying affected system-level processes. The authors applied a mathematical model to evaluate time-domain components of anesthetic amnesia in human subjects...
Information loss over time defines the memory defect of propofol: a comparative response with thiopental and dexmedetomidineRobert A Veselis
Memorial Sloan-Kettering Cancer Center and Weill Medical College of Cornell University, 1275 York Avenue, New York, NY, USA
Anesthesiology 101:831-41. 2004..Sedation seems to impair the acquisition or encoding of material into long-term memory. Therefore, the putative targets of drug-induced amnesia by propofol are processes associated with retention of material in long-term memory...
Propofol-induced alpha rhythmVladimir A Feshchenko
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Neuropsychobiology 50:257-66. 2004..Baseline properties of the oscillatory system underlying the initial resting alpha-rhythm recover completely as drug concentration decays to negligible values...
Comparison of the EEG effects of midazolam, thiopental, and propofol: the role of underlying oscillatory systemsV A Feshchenko
Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Neuropsychobiology 35:211-20. 1997..The differences between the beta-rhythms induced by drug infusion and previously described 'sleep spindles' are discussed. We conclude that a quantitative analysis of beta-rhythms can differentiate the effects of these drugs on the EEG...
Enhanced visual memory effect for negative versus positive emotional content is potentiated at sub-anaesthetic concentrations of thiopentalK O Pryor
Department of Anesthesiology, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
Br J Anaesth 93:348-55. 2004..It is not known how gamma aminobutyric acid (GABA)ergic drugs affect the processes involved in memory modulation. This study investigates whether memory for negative emotional stimuli is more refractory to the effects of GABAergic drugs...
To sleep, perchance to decode?Robert A Veselis
Anesthesiology 105:1278-9; author reply 1279-80. 2006
