Research Topics
| E S VenkatramanSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
A permutation test to compare receiver operating characteristic curvesE S Venkatraman
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
Biometrics 56:1134-8. 2000..Here we extend the underlying concepts to develop a permutation test for continuous unpaired data, and we study its properties through simulations...
Properties of a nonparametric test for early comparison of treatments in clinical trials in the presence of surrogate endpointsE S Venkatraman
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biometrics 55:1171-6. 1999..Our research indicates that, in the absence of modeling assumptions, auxiliary information derived from surrogate endpoints can provide significant additional information only under special circumstances...
Late rectal toxicity after conformal radiotherapy of prostate cancer (I): multivariate analysis and dose-responseM W Skwarchuk
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA
Int J Radiat Oncol Biol Phys 47:103-13. 2000....
Analysis of biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer using dose-distribution variables and tumor control probability modelsS Levegrun
Department Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 47:1245-60. 2000..To investigate tumor control following three-dimensional conformal radiation therapy (3D-CRT) of prostate cancer and to identify dose-distribution variables that correlate with local control assessed through posttreatment prostate biopsies...
Fitting tumor control probability models to biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer: pitfalls in deducing radiobiologic parameters for tumors from clinical dataS Levegrun
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Int J Radiat Oncol Biol Phys 51:1064-80. 2001..We discuss differences in the radiobiologic parameters and dose-response curves and demonstrate pitfalls in interpreting the results...
Late rectal bleeding after conformal radiotherapy of prostate cancer. II. Volume effects and dose-volume histogramsA Jackson
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 49:685-98. 2001..The purpose of this study is to identify features of the cumulative dose-volume histogram (DVH) for the rectal wall that correlate with late rectal bleeding after 3D-CRT for prostate cancer...
Postimplantation dosimetric analysis of permanent transperineal prostate implantation: improved dose distributions with an intraoperative computer-optimized conformal planning techniqueM J Zelefsky
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 48:601-8. 2000..To compare the target coverage and dose to normal tissues after I-125 transperineal permanent implantation (TPI) of the prostate in 90 patients treated with one of three different transperineal techniques...
Important prognostic factors in patients with malignant pleural mesothelioma, managed surgicallyV W Rusch
Department of Surgery, and Biostatistics Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 68:1799-804. 1999..The factors influencing outcome after resection of malignant pleural mesothelioma (MPM) are controversial. This analysis of a prospective surgical database identifies important prognostic factors...
Outcome predictors for the increasing PSA state after definitive external-beam radiotherapy for prostate cancerMichael J Zelefsky
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
J Clin Oncol 23:826-31. 2005..To identify predictors of distant metastases (DM) among patients who develop an isolated prostate-specific antigen (PSA) relapse after definitive external-beam radiotherapy for clinically localized prostate cancer...
Identification of prognostic factors in advanced epithelial ovarian carcinomaD S Chi
Gynecology Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Gynecol Oncol 82:532-7. 2001....
High dose radiation delivered by intensity modulated conformal radiotherapy improves the outcome of localized prostate cancerM J Zelefsky
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
J Urol 166:876-81. 2001..Intensity modulated radiation therapy is associated with minimal rectal and bladder toxicity, and, hence, represents the treatment delivery approach with the most favorable risk-to-benefit ratio...
Properties of analysis methods that account for clustering in volume-outcome studies when the primary predictor is cluster sizeKatherine S Panageas
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Stat Med 26:2017-35. 2007..By contrast, the cluster weighted GEE method is inefficient...
Two-stage designs for gene-disease association studies with sample size constraintsJaya M Satagopan
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Biometrics 60:589-97. 2004....
Morbidity and mortality after neoadjuvant therapy for lung cancer: the risks of right pneumonectomyJ Martin
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 72:1149-54. 2001..However, right pneumonectomy is associated with a significantly increased risk and should be performed only in selected patients...
Optimal two-stage design for a series of pilot trials of new agentsT J Yao
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biometrics 54:1183-9. 1998..The reliability of the results is evaluated using the bootstrap...
High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patientsMichael J Zelefsky
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 53:1111-6. 2002..To report the acute and late toxicity and preliminary biochemical outcomes in 772 patients with clinically localized prostate cancer treated with high-dose intensity-modulated radiotherapy (IMRT)...
The ability of preoperative serum CA-125 to predict optimal primary tumor cytoreduction in stage III epithelial ovarian carcinomaD S Chi
Gynecology Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Gynecol Oncol 77:227-31. 2000..These patients may be candidates for initial laparoscopic evaluation to obtain a confirmatory tissue diagnosis and to determine resectability...
Two-stage designs for gene-disease association studiesJaya M Satagopan
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biometrics 58:163-70. 2002..This translates to screening all the markers on approximately one quarter of the required sample size in stage 1...
Circular binary segmentation for the analysis of array-based DNA copy number dataAdam B Olshen
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Biostatistics 5:557-72. 2004..The method is evaluated by simulation and is demonstrated on cell line data with known copy number alterations and on a breast cancer cell line data set...
A faster circular binary segmentation algorithm for the analysis of array CGH dataE S Venkatraman
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Bioinformatics 23:657-63. 2007..This makes the full permutation approach computationally prohibitive for the newer arrays that contain tens of thousands markers and highlights the need for a faster algorithm...
