Research Topics
| E S VenkatramanSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Normalization of serum testosterone levels in patients treated with neoadjuvant hormonal therapy and three-dimensional conformal radiotherapy for prostate cancerGilbert D A Padula
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 52:439-43. 2002..Lower baseline testosterone levels predict for a delay in testosterone normalization, and the persistence of symptoms related to androgen deprivation correlates with low testosterone levels...- Epidermal growth factor receptor signaling in adenocarcinomas with bronchioloalveolar componentsInderpal S Sarkaria
Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 85:216-23. 2008..This study assesses EGFR signaling in these tumors... - A faster circular binary segmentation algorithm for the analysis of array CGH dataE S Venkatraman
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Bioinformatics 23:657-63. 2007..This makes the full permutation approach computationally prohibitive for the newer arrays that contain tens of thousands markers and highlights the need for a faster algorithm... - Late rectal toxicity after conformal radiotherapy of prostate cancer (I): multivariate analysis and dose-responseM W Skwarchuk
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA
Int J Radiat Oncol Biol Phys 47:103-13. 2000.... - Analysis of biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer using dose-distribution variables and tumor control probability modelsS Levegrun
Department Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 47:1245-60. 2000..To investigate tumor control following three-dimensional conformal radiation therapy (3D-CRT) of prostate cancer and to identify dose-distribution variables that correlate with local control assessed through posttreatment prostate biopsies... - Fitting tumor control probability models to biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer: pitfalls in deducing radiobiologic parameters for tumors from clinical dataS Levegrun
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Int J Radiat Oncol Biol Phys 51:1064-80. 2001..We discuss differences in the radiobiologic parameters and dose-response curves and demonstrate pitfalls in interpreting the results... - Late rectal bleeding after conformal radiotherapy of prostate cancer. II. Volume effects and dose-volume histogramsA Jackson
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 49:685-98. 2001..The purpose of this study is to identify features of the cumulative dose-volume histogram (DVH) for the rectal wall that correlate with late rectal bleeding after 3D-CRT for prostate cancer... - Postimplantation dosimetric analysis of permanent transperineal prostate implantation: improved dose distributions with an intraoperative computer-optimized conformal planning techniqueM J Zelefsky
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 48:601-8. 2000..To compare the target coverage and dose to normal tissues after I-125 transperineal permanent implantation (TPI) of the prostate in 90 patients treated with one of three different transperineal techniques... - A permutation test to compare receiver operating characteristic curvesE S Venkatraman
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
Biometrics 56:1134-8. 2000..Here we extend the underlying concepts to develop a permutation test for continuous unpaired data, and we study its properties through simulations... - Important prognostic factors in patients with malignant pleural mesothelioma, managed surgicallyV W Rusch
Department of Surgery, and Biostatistics Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 68:1799-804. 1999..The factors influencing outcome after resection of malignant pleural mesothelioma (MPM) are controversial. This analysis of a prospective surgical database identifies important prognostic factors... - Two-stage designs for gene-disease association studies with sample size constraintsJaya M Satagopan
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Biometrics 60:589-97. 2004.... - High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patientsMichael J Zelefsky
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 53:1111-6. 2002..To report the acute and late toxicity and preliminary biochemical outcomes in 772 patients with clinically localized prostate cancer treated with high-dose intensity-modulated radiotherapy (IMRT)... - Two-stage designs for gene-disease association studiesJaya M Satagopan
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biometrics 58:163-70. 2002..This translates to screening all the markers on approximately one quarter of the required sample size in stage 1... - Outcome predictors for the increasing PSA state after definitive external-beam radiotherapy for prostate cancerMichael J Zelefsky
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
J Clin Oncol 23:826-31. 2005..To identify predictors of distant metastases (DM) among patients who develop an isolated prostate-specific antigen (PSA) relapse after definitive external-beam radiotherapy for clinically localized prostate cancer... - Circular binary segmentation for the analysis of array-based DNA copy number dataAdam B Olshen
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Biostatistics 5:557-72. 2004..The method is evaluated by simulation and is demonstrated on cell line data with known copy number alterations and on a breast cancer cell line data set... - Optimal two-stage design for a series of pilot trials of new agentsT J Yao
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biometrics 54:1183-9. 1998..The reliability of the results is evaluated using the bootstrap... - Properties of a nonparametric test for early comparison of treatments in clinical trials in the presence of surrogate endpointsE S Venkatraman
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biometrics 55:1171-6. 1999..Our research indicates that, in the absence of modeling assumptions, auxiliary information derived from surrogate endpoints can provide significant additional information only under special circumstances... - Morbidity and mortality after neoadjuvant therapy for lung cancer: the risks of right pneumonectomyJ Martin
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 72:1149-54. 2001..However, right pneumonectomy is associated with a significantly increased risk and should be performed only in selected patients... - Identification of prognostic factors in advanced epithelial ovarian carcinomaD S Chi
Gynecology Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Gynecol Oncol 82:532-7. 2001.... - High dose radiation delivered by intensity modulated conformal radiotherapy improves the outcome of localized prostate cancerM J Zelefsky
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
J Urol 166:876-81. 2001..Intensity modulated radiation therapy is associated with minimal rectal and bladder toxicity, and, hence, represents the treatment delivery approach with the most favorable risk-to-benefit ratio... - Properties of analysis methods that account for clustering in volume-outcome studies when the primary predictor is cluster sizeKatherine S Panageas
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Stat Med 26:2017-35. 2007..By contrast, the cluster weighted GEE method is inefficient... - The ability of preoperative serum CA-125 to predict optimal primary tumor cytoreduction in stage III epithelial ovarian carcinomaD S Chi
Gynecology Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Gynecol Oncol 77:227-31. 2000..These patients may be candidates for initial laparoscopic evaluation to obtain a confirmatory tissue diagnosis and to determine resectability... - Identification of prognostic factors after positive second-look surgery in epithelial ovarian carcinomaWayne A McCreath
Department of Surgery, Gynecology Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, MRI-1026, New York, NY 10021, USA
Gynecol Oncol 102:8-14. 2006..No individual chemotherapy treatment imparted a survival advantage. Novel that therapeutic approaches are needed in this setting... - Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinibGregory J Riely
Thoracic Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Clin Cancer Res 12:839-44. 2006..We undertook this study to explore the relationship between EGFR mutation type and clinical variables, including treatment with gefitinib and erlotinib... - Guidelines and selection criteria for secondary cytoreductive surgery in patients with recurrent, platinum-sensitive epithelial ovarian carcinomaDennis S Chi
Gynecology Service, Department of Surgery Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Cancer 106:1933-9. 2006.... - Evaluation of postradiotherapy PSA patterns and correlation with 10-year disease free survival outcomes for prostate cancerMichael J Zelefsky
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 66:382-8. 2006.... - A comparison of intensity-modulated radiation therapy and concomitant boost radiotherapy in the setting of concurrent chemotherapy for locally advanced oropharyngeal carcinomaNancy Y Lee
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 66:966-74. 2006..intensity-modulated radiotherapy (IMRT) in the setting of concurrent chemotherapy (CT) for locally advanced oropharyngeal carcinoma... - Salvage re-irradiation for recurrent head and neck cancerNancy Lee
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 68:731-40. 2007..To present a retrospective review of treatment outcomes for recurrent head and neck (HN) cancer patients treated with re-irradiation (re-RT) at a single medical center... - The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancerFabio Maria Vecchio
Department of Pathology, Catholic University of the Sacred Heart, Rome, Italy
Int J Radiat Oncol Biol Phys 62:752-60. 2005.... 
High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesionsYoshiya Yamada
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 71:484-90. 2008..To report tumor control and toxicity for patients treated with image-guided intensity-modulated radiotherapy (RT) for spinal metastases with high-dose single-fraction RT...- Long-term results of combined-modality therapy in resectable non-small-cell lung cancerJocelyne Martin
Thoracic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 20:1989-95. 2002..Survival is significantly influenced by patient age, complete resection, pathologic stage, and pneumonectomy. These results can help guide standard clinical practice and emphasize the need for novel induction regimens... - Risk group dependence of dose-response for biopsy outcome after three-dimensional conformal radiation therapy of prostate cancerSabine Levegrun
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Radiother Oncol 63:11-26. 2002..We fit phenomenological tumor control probability (TCP) models to biopsy outcome after three-dimensional conformal radiation therapy (3D-CRT) of prostate cancer patients to quantify the local dose-response of prostate cancer... - Dose-volume factors contributing to the incidence of radiation pneumonitis in non-small-cell lung cancer patients treated with three-dimensional conformal radiation therapyEllen D Yorke
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 54:329-39. 2002.... - Clinical pattern and pathologic stage but not histologic features predict outcome for bronchioloalveolar carcinomaMichael I Ebright
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 74:1640-6; discussion 1646-7. 2002..The favorable survival of stage III/IV BAC indicates that the current staging system does not fully describe this disease in patients undergoing resection because of its distinct tumor behavior... - Predictors of biochemical outcome with salvage conformal radiotherapy after radical prostatectomy for prostate cancerMatthew S Katz
Departments of Radiation Oncology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 21:483-9. 2003..Salvage neoadjuvant androgen deprivation therapy may improve short-term biochemical control, but it requires further study... - Ten-year experience with laparoscopy on a gynecologic oncology service: analysis of risk factors for complications and conversion to laparotomyDennis S Chi
Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Am J Obstet Gynecol 191:1138-45. 2004..The purpose of this study was to analyze our initial 10-year experience with laparoscopy and to determine risk factors for complications and conversions to laparotomy for technical difficulty... - Breast cancer metastatic to abdomen and pelvis: role of surgical resectionRam Eitan
Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Gynecol Oncol 90:397-401. 2003..Surgical resection of metachronous metastatic breast cancer to the abdomen and pelvis may be an important component of the management of this disease and should be considered in candidate patients... - Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomasDuyKhanh Pham
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Clin Oncol 24:1700-4. 2006..Investigators have reported an association between EGFR mutations and the amount and duration of cigarette smoking, with the highest incidence of mutations seen in never smokers... - SCCRO expression correlates with invasive progression in bronchioloalveolar carcinomaInderpal S Sarkaria
Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 78:1734-41. 2004..We hypothesized that SCCRO expression would correlate with invasive tumor phenotypes and worse survival in BAC... - Mesorectal lymph node involvement and prognostic implications at total pelvic exenteration for gynecologic malignanciesSusannah M Mourton
Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, MRI-1026, New York, NY 10021, USA
Gynecol Oncol 100:533-6. 2006..Patients with positive mesorectal lymph nodes appear to have a worse outcome with a shorter time to recurrence of disease...