Affiliation: Memorial Sloan-Kettering Cancer Center
Thorek D, Watson P, Lee S, Ku A, Bournazos S, Braun K, et al
. Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis. Sci Transl Med. 2016;8:367ra167 pubmed
..Furthermore, cell-specific SATA uptake may have a broader use for molecularly guided diagnosis and therapy in other cancers. ..
Gerdtsson A, Poon J, Thorek D, Mucci L, Evans M, Scardino P, et al
. Anthropometric Measures at Multiple Times Throughout Life and Prostate Cancer Diagnosis, Metastasis, and Death. Eur Urol. 2015;68:1076-82 pubmed publisher
..Conversely, measurements at birth and adolescence are not associated with PCa prevalence or outcome. Increased weight and body mass index in adults is associated with a higher risk of prostate cancer metastasis and death. ..
Vilhelmsson Timmermand O, Santos E, Thorek D, Evans Axelsson S, Bjartell A, Lilja H, et al
. Radiolabeled antibodies in prostate cancer: a case study showing the effect of host immunity on antibody bio-distribution. Nucl Med Biol. 2015;42:375-80 pubmed publisher
..Investigators utilizing xenograft models need to assess not only radiolabeling strategies, but also the host immunological status. ..
McDevitt M, Thorek D, Hashimoto T, Gondo T, Veach D, Sharma S, et al
. Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer. Nat Commun. 2018;9:1629 pubmed publisher
..Imaging data in nonhuman primates support the possibility of utilizing hu11B6 in man. ..