MENG FU TSOU

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. pmc Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells
    Meng Fu Bryan Tsou
    Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Dev Cell 17:344-54. 2009
  2. pmc The conversion of centrioles to centrosomes: essential coupling of duplication with segregation
    Won Jing Wang
    Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Cell Biol 193:727-39. 2011
  3. pmc CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
    Won Jing Wang
    Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Nat Cell Biol 15:591-601. 2013

Research Grants

  1. The Control of Centriole Duplication and Degeneration
    Meng Fu Bryan Tsou; Fiscal Year: 2010

Collaborators

  • Won Jing Wang
  • Jeffrey D Amack
  • Mary G Goll
  • Rajesh Soni
  • Hwee Goon Tay
  • Geoffrey S Perumal
  • John M Asara
  • Frank P Macaluso
  • Kunihiro Uryu
  • Rajesh Kumar Soni

Detail Information

Publications3

  1. pmc Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells
    Meng Fu Bryan Tsou
    Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Dev Cell 17:344-54. 2009
    ..Our results indicate that Plk1 and separase act at different times during M phase to license centrosome duplication, reminiscent of their roles in removing cohesin from chromosomes...
  2. pmc The conversion of centrioles to centrosomes: essential coupling of duplication with segregation
    Won Jing Wang
    Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Cell Biol 193:727-39. 2011
    ..We thus uncovered a Plk1-dependent mechanism whereby duplication and segregation are coupled to maintain centriole homeostasis...
  3. pmc CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
    Won Jing Wang
    Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Nat Cell Biol 15:591-601. 2013
    ..CEP162 is thus an axoneme-recognition protein pre-tethered at centriole distal ends before ciliogenesis to promote and restrict transition zone formation specifically at the cilia base...

Research Grants2

  1. The Control of Centriole Duplication and Degeneration
    Meng Fu Bryan Tsou; Fiscal Year: 2010
    ..As a consequence, centrosome number is precisely regulated to ensure proper cell division. The goal of my research is to understand how the centrosome number is maintained during cell division and development. ..