Research Topics
| Larissa K TempleSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
Individualized prediction of colon cancer recurrence using a nomogramMartin R Weiser
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
J Clin Oncol 26:380-5. 2008..Although easy to implement, there remains significant heterogeneity within each stage grouping. In the era of multimodality treatment, a more refined tool is needed to predict recurrence...- Factors associated with sphincter-preserving surgery for rectal cancer at national comprehensive cancer network centersLarissa K Temple
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg 250:260-7. 2009..To determine rate and predictors of sphincter-preserving surgery (SPS) for rectal cancer patients treated at specialty institutions... 
The development of a validated instrument to evaluate bowel function after sphincter-preserving surgery for rectal cancerLarissa K Temple
Department of Surgery, Division of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Dis Colon Rectum 48:1353-65. 2005..Therefore, the purpose of this study was to develop an instrument to evaluate bowel function after sphincter-preserving surgery...- Effects of obesity in rectal cancer surgeryHueylan Chern
Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
J Am Coll Surg 211:55-60. 2010..In this study, we evaluate whether higher body mass index (BMI) compromises surgical resection in patients with locally advanced, mid-to-low rectal cancer after neoadjuvant therapy, adversely affecting long-term oncologic outcomes... - Identification of patients with high-risk stage II colon cancer for adjuvant therapyHak Mien Quah
Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Dis Colon Rectum 51:503-7. 2008..The purpose of this study was to assess the prognostic significance of commonly reported clinicopathologic features of Stage II colon cancer to identify high-risk patients... - Challenging the feasibility and clinical significance of current guidelines on lymph node examination in rectal cancer in the era of neoadjuvant therapyAnand Govindarajan
Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
J Clin Oncol 29:4568-73. 2011..We sought to examine the feasibility and clinical significance of current guidelines on nodal assessment in patients with rectal cancer (RC) treated with neoadjuvant radiation... - Squamous-cell carcinoma of the rectum: a rare but curable tumorCaio S R Nahas
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Dis Colon Rectum 50:1393-400. 2007..This study was designed to evaluate one institution's experience with treatment outcomes for rectal squamous-cell carcinoma... - Can differences in bowel function after surgery for rectal cancer be identified by the European Organization for Research and Treatment of Cancer quality of life instrument?Heather B Neuman
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, New York 10021, USA
Ann Surg Oncol 14:1727-34. 2007.... 
T1 adenocarcinoma of the rectum: transanal excision or radical surgery?David J Bentrem
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Ann Surg 242:472-7; discussion 477-9. 2005..We performed a retrospective evaluation of patients with T1 rectal cancers treated by either transanal excision or radical resection at our institution to assess patient selection, cancer recurrence, and survival...- Significance of acellular mucin pools in rectal carcinoma after neoadjuvant chemoradiotherapyJinru Shia
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Am J Surg Pathol 35:127-34. 2011.... - Surgical salvage of recurrent rectal cancer after transanal excisionMartin R Weiser
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Dis Colon Rectum 48:1169-75. 2005..This study examines surgical salvage of locally recurrent rectal cancer following transanal excision of early tumors... - A predictive model for lymph node yield in colon cancer resection specimensGarrett M Nash
Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Ann Surg 253:318-22. 2011..To develop a predictive model of lymph node yield in a series of colon cancer resection specimens with detailed anatomic and surgical technique data... - Treatment for patients with rectal cancer and a clinical complete response to neoadjuvant therapy: a decision analysisHeather B Neuman
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Dis Colon Rectum 52:863-71. 2009..Therefore, the objective was to develop a decision-analytic model to evaluate the relative benefits of surgery vs. observation in rectal cancer patients who achieve clinical complete response after neoadjuvant chemoradiation... - Sphincter preservation in low rectal cancer is facilitated by preoperative chemoradiation and intersphincteric dissectionMartin R Weiser
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Surg 249:236-42. 2009.... - Predictive clinicopathologic factors for limited response of T3 rectal cancer to combined modality therapyAnne Y Lin
Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Colorectal Dis 23:243-9. 2008..The aim of this study was to identify pretreatment factors associated with poor tumor response to neoadjuvant chemoradiation... - Long-term survival after transanal excision of T1 rectal cancerGarrett M Nash
Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Dis Colon Rectum 52:577-82. 2009..However, the impact of transanal excision on cancer mortality has not been adequately studied. The purpose of this study was to compare oncologic outcomes of transanal excision with those of radical resection... - Whole-mount pathologic analysis of rectal cancer following neoadjuvant therapy: implications of margin status on long-term oncologic outcomeJames J Mezhir
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg 256:274-9. 2012..We set out to determine the long-term oncologic impact of resection margins in patients with locally advanced rectal cancer using a comprehensive pathologic whole-mount section analysis... - Recurrence rates and prognostic factors in ypN0 rectal cancer after neoadjuvant chemoradiation and total mesorectal excisionAnand Govindarajan
Department of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 18:3666-72. 2011..Patients with pathologically node-negative tumors have an improved prognosis, but recurrence patterns and independent prognostic factors in these patients have been incompletely characterized... - Limitations of early rectal cancer nodal staging may explain failure after local excisionRon G Landmann
Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Dis Colon Rectum 50:1520-5. 2007..The limitations of endorectal ultrasound in accurately staging nodal disease in early rectal lesions may, in part, explain the relatively high recurrence rates seen after local excision... - Sacral resection for recurrent rectal cancer: analysis of morbidity and treatment resultsGenevieve B Melton
Division of Colorectal Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Dis Colon Rectum 49:1099-107. 2006..This procedure has a low cure rate but may provide local disease control with acceptable morbidity... - Pulmonary recurrence predominates after combined modality therapy for rectal cancer: an original retrospective studyPeirong Ding
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg 256:111-6. 2012..To characterize patterns of recurrence in locally advanced rectal cancer treated with combined modality therapy (CMT): neoadjuvant chemoradiation + total mesorectal excision + adjuvant chemotherapy... - Oncologic outcomes of salvage surgery for epidermoid carcinoma of the anus initially managed with combined modality therapyRobert P Akbari
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
Dis Colon Rectum 47:1136-44. 2004..persistence) after chemoradiation (when salvage is potentially curative), absence of nodal disease at salvage, and negative margins. Salvage inguinal lymph node dissection after failed chemoradiation therapy also is potentially curative... - Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panelJinru Shia
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Am J Surg Pathol 33:1639-45. 2009..Such a cost-effective approach carries significant implication, as immunohistochemistry is being widely used as first-line screening for HNPCC... - Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapyJames D Smith
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg 256:965-72. 2012.... - Positron emission tomography detection of distant metastatic or synchronous disease in patients with locally advanced rectal cancer receiving preoperative chemoradiationCaio S R Nahas
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 15:704-11. 2008.... - Response to neoadjuvant therapy in patients with early age-of-onset rectal cancerEmily Steinhagen
Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Dis Colon Rectum 56:58-63. 2013..The response to neoadjuvant treatment in patients ≤ 50 years of age is not known. Factors affecting the response to neoadjuvant therapy in this age group have not been evaluated... - Early postoperative intraperitoneal chemotherapy following cytoreductive surgery for appendiceal mucinous neoplasms with isolated peritoneal metastasisPatrick L Wagner
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Dis Colon Rectum 55:407-15. 2012..At our institution, patients undergoing complete cytoreduction in this setting typically receive multiple cycles of early postoperative intraperitoneal chemotherapy... - Prospective immunohistochemical analysis of primary colorectal cancers for loss of mismatch repair protein expressionSteven A Lee-Kong
Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Clin Colorectal Cancer 9:255-9. 2010..We examined the value of routine immunohistochemistry (IHC) for MMR proteins in patients with colorectal cancer (CRC) undergoing resection at a single institution... - Patterns of morphologic alteration in residual rectal carcinoma following preoperative chemoradiation and their association with long-term outcomeJinru Shia
Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Am J Surg Pathol 28:215-23. 2004..Our results demonstrate distinct morphologic features in treated rectal carcinomas that are prognostically relevant... - Anastomotic leak is not associated with oncologic outcome in patients undergoing low anterior resection for rectal cancerJames D Smith
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg 256:1034-8. 2012..To examine the association between anastomotic leak and oncologic outcome after anterior resection, stratifying for defunctioning stoma... - Is internet information adequate to facilitate surgical decision-making in familial adenomatous polyposis?Heather B Neuman
Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Room C 1079, New York, New York 10021, USA
Dis Colon Rectum 50:2135-41. 2007..Our objective was to examine internet information regarding prophylactic surgery for familial adenomatous polyposis to determine its adequacy in facilitating patient participation in surgical decision-making... - Prevalence of perianal intraepithelial neoplasia in HIV-infected patients referred for high-resolution anoscopyCaio S R Nahas
Colorectal Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
Dis Colon Rectum 49:1581-6. 2006..Our data suggest that anal canal neoplasia often is accompanied by perianal disease and illustrates the need for biopsy of any suspicious perianal lesions... - Accuracy of endorectal ultrasound for measurement of the closest predicted radial mesorectal margin for rectal cancerP Terry Phang
St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
Dis Colon Rectum 55:59-64. 2012..Endorectal ultrasound is also used to assess the clinical stage of the cancer that will determine the recommendation for neoadjuvant chemoradiation, but it has not been used to assess the closest predicted radial margin... - Rectal cancer patients' quality of life with a temporary stoma: shifting perspectivesHeather B Neuman
Department of Surgery, University of Wisconsin, Madison, Wisconsin, USA
Dis Colon Rectum 55:1117-24. 2012..Patients with rectal cancer who have a temporary ostomy report good quality of life despite identifying a number of stoma-related difficulties... - Anal versus rectal melanoma: does site of origin predict outcome?Danielle M Bello
1 Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 2 Department of Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, New York
Dis Colon Rectum 56:150-7. 2013..Anatomic site is a predictive factor in subtypes of cutaneous and mucosal melanoma... - Morbidity of rectosigmoid resection and primary anastomosis in patients undergoing primary cytoreductive surgery for advanced epithelial ovarian cancerSusannah M Mourton
Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, MRI-1026, New York, NY 10021, USA
Gynecol Oncol 99:608-14. 2005..Protective ileostomy is not always necessary and should be used selectively... - Is there a role for decision aids in cancer-related decisions?Heather B Neuman
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, United States
Crit Rev Oncol Hematol 62:240-50. 2007..Some studies suggest less decisional conflict and improved satisfaction with decision-making as a result. Whether use of a decision aid impacts the actual decisions made by patients, however, is less evident...