Joseph C Sun

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi NK cells and immune "memory"
    Joseph C Sun
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Immunol 186:1891-7. 2011
  2. ncbi Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155
    Carolyn L Zawislak
    Immunology Program and Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065 and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143
    Proc Natl Acad Sci U S A 110:6967-72. 2013
  3. ncbi Proinflammatory cytokine signaling required for the generation of natural killer cell memory
    Joseph C Sun
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Exp Med 209:947-54. 2012
  4. ncbi MicroRNA function in NK-cell biology
    Aimee M Beaulieu
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Immunol Rev 253:40-52. 2013
  5. ncbi Protein kinase C-θ clustering at immunological synapses amplifies effector responses in NK cells
    Ernesto Merino
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Immunol 189:4859-69. 2012
  6. ncbi Extrathymic development of murine T cells after bone marrow transplantation
    Amanda M Holland
    Department of Immunology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    J Clin Invest 122:4716-26. 2012
  7. ncbi NK cell development, homeostasis and function: parallels with CD8⁺ T cells
    Joseph C Sun
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Nat Rev Immunol 11:645-57. 2011

Collaborators

  • Lewis L Lanier
  • Jarrod A Dudakov
  • Xin Liu
  • Mark H Kaplan
  • Aimee M Beaulieu
  • Carolyn L Zawislak
  • Natalie A Bezman
  • Amanda M Holland
  • Ernesto Merino
  • David Canner
  • Mehrdad Matloubian
  • Jenny Karo
  • Alexander Y Rudensky
  • Jang Eun Lee
  • Gabriel B Loeb
  • Jessie Brill
  • Odette M Smith
  • Matthew A Firth
  • Jennifer J Tsai
  • Johannes L Zakrzewski
  • Natalie V Singer
  • Roshni Basu
  • Morgan Huse
  • Alan M Hanash
  • Thushara P Abeyweera
  • Mallory L West
  • Marcel R m van den Brink

Detail Information

Publications7

  1. ncbi NK cells and immune "memory"
    Joseph C Sun
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Immunol 186:1891-7. 2011
    ....
  2. ncbi Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155
    Carolyn L Zawislak
    Immunology Program and Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065 and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143
    Proc Natl Acad Sci U S A 110:6967-72. 2013
    ..NK cells constitutively expressing Noxa and SOCS1 exhibit profound defects in expansion during the response to MCMV infection, suggesting that their regulation by miR-155 promotes antiviral immunity...
  3. ncbi Proinflammatory cytokine signaling required for the generation of natural killer cell memory
    Joseph C Sun
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Exp Med 209:947-54. 2012
    ..Understanding the full contribution of inflammatory cytokine signaling to the NK cell response against viral infection will be of interest for the development of vaccines and therapeutics...
  4. ncbi MicroRNA function in NK-cell biology
    Aimee M Beaulieu
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Immunol Rev 253:40-52. 2013
    ..Furthermore, we discuss the impact of NK cells on the entire immune system during global and specific microRNA ablation in the settings of inflammation, infection, and immune dysregulation...
  5. ncbi Protein kinase C-θ clustering at immunological synapses amplifies effector responses in NK cells
    Ernesto Merino
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Immunol 189:4859-69. 2012
    ..Taken together, our results provide a cell biological basis for the role of PKCθ clustering during NK cell activation, and highlight the importance of subcellular compartmentalization for lymphocyte signal transduction...
  6. ncbi Extrathymic development of murine T cells after bone marrow transplantation
    Amanda M Holland
    Department of Immunology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    J Clin Invest 122:4716-26. 2012
    ..These findings demonstrate the potential of extrathymic T cell development for T cell reconstitution in patients with limited thymic function...
  7. ncbi NK cell development, homeostasis and function: parallels with CD8⁺ T cells
    Joseph C Sun
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Nat Rev Immunol 11:645-57. 2011
    ..In this Review, we highlight the many stages that an NK cell progresses through during its remarkable lifetime, discussing similarities and differences with its close relative, the cytotoxic CD8(+) T cell...